|
| << vorige | volgende >> |
Tijdschrift beschrijving
Alle jaargangen van het bijbehorende tijdschrift
Alle afleveringen van het bijbehorende jaargang
Alle artikelen van de bijbehorende aflevering
Details van artikel 164 van 262 gevonden artikelen
| Titel: |
Manufacturing Drug Loaded Chitosan Microspheres by Spray Drying: Development, Characterization, and Potential Use in Dentistry |
| Auteur: |
Braga, Glaucia K. Oliveira, Wanderley P. |
| Verschenen in: |
Drying technology |
| Paginering: | Jaargang 25 (2007) nr. 2 pagina's 303-310 |
| Jaar: |
2007-02 |
| Inhoud: |
The aim of this work was to determine specifications for spray-drying manufacturing of sustained-release drug-loaded microparticles with potential application in dentistry. Chitosan was used as the microencapsulation polymer and ketoprofen as the model drug. A 1:1 chitosan/ketoprofen suspension was spray-dried under different operating conditions. The size distribution, morphology, total drug load, and release profile of the powders were characterized. In vitro release studies were performed with the powder samples entrapped in cellulose dialysis tubes. The microparticles produced had a narrow size distribution (mean diameter ranging from 2.11 to 3.27 µm), good sphericity, and a smooth surface. In vitro release studies showed a linear drug dissolution behavior. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 164 van 262 gevonden artikelen
| << vorige | volgende >> |