Digitale Bibliotheek
Sluiten Bladeren door artikelen uit een tijdschrift
     Tijdschrift beschrijving
       Alle jaargangen van het bijbehorende tijdschrift
         Alle afleveringen van het bijbehorende jaargang
                                       Alle artikelen van de bijbehorende aflevering
 
                             95 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Acriflavine and proflavine hemisulfate as potential antivirals by targeting Mpro Liang, Jing

129 C p.
artikel
2 Allyl phenyl selenides as H2O2 acceptors to develop ROS-responsive theranostic prodrugs Yang, Xue-Yan

129 C p.
artikel
3 Anti-inflammatory butanolides and lignanoids from the root of Machilus zuihoensis var. mushaensis Yang, Shuen-Shin

129 C p.
artikel
4 Anti-proliferative tirucallane triterpenoids from gum resin of Boswellia sacra Zhang, Bingyang

129 C p.
artikel
5 Assessing p-tolyloxy-1,3,4-oxadiazole acetamides as lipoxygenase inhibitors assisted by in vitro and in silico studies Bashir, Bushra

129 C p.
artikel
6 Biosynthesis, characterization and biomedical potential of Arthrospira indica SOSA-4 mediated SeNPs Afzal, Bushra

129 C p.
artikel
7 Callicarpnoids A–C, structurally intriguing ent-Clerodane diterpenoid dimers with cytotoxicity against MCF-7 and HCT-116 cell lines from Callicarpa arborea Roxb Cheng, Bin

129 C p.
artikel
8 Cationic RGD peptidomimetic nanoconjugates as effective tumor targeting gene delivery vectors with antimicrobial potential Ahmadi, Zeba

129 C p.
artikel
9 CC1007, a small molecular compound, suppresses multiple myeloma via upregulation of Nur77 Zhu, Shicong

129 C p.
artikel
10 Chemical synthesis of fluorinated and iodinated 17β-HSD3 inhibitors and evaluation for imaging prostate cancer tumors and tissue biodistribution Poirier, Donald

129 C p.
artikel
11 Construction of an in vivo NIR fluorescent probe for revealing the correlation between inflammation and mitochondrial hydrogen sulfide and viscosity Cui, Yali

129 C p.
artikel
12 Design and synthesis of N-(1-(6-(substituted phenyl)-pyridazin-3-yl)-piperidine-3-yl)-amine derivatives as JMJD6 inhibitors Qian, Yuqing

129 C p.
artikel
13 Design, synthesis and antitumor activity evaluation of novel indole acrylamide derivatives as IMPDH inhibitors Jia, Hong-Wei

129 C p.
artikel
14 Design, synthesis and biological evaluation of 2-aminopyridine derivatives as USP7 inhibitors Xu, Xiaoming

129 C p.
artikel
15 Design, synthesis and biological evaluation of dehydroabietic acid derivative as potent vasodilatory agents Wu, Dan

129 C p.
artikel
16 Design, synthesis, and biological evaluation of novel sulfamoylbenzamide derivatives as HBV capsid assembly modulators Wang, Shuo

129 C p.
artikel
17 Design, synthesis and biological evaluation of novel tumor hypoxia-activated EGFR tyrosine kinase inhibitors Jia, Tingting

129 C p.
artikel
18 Design, synthesis and biological evaluation of pyranocarbazole derivatives against Alzheimer’s disease, with antioxidant, neuroprotective and cognition enhancing properties Zang, Yingda

129 C p.
artikel
19 Design, synthesis, and in vitro evaluation of novel antifungal triazoles containing substituted 1,2,3-triazole-methoxyl side chains Xie, Fei

129 C p.
artikel
20 Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities Ahmed, Asmaa H.H.

129 C p.
artikel
21 Design, synthesis and pharmacological evaluation of 2-arylurea-1,3,5-triazine derivative (XIN-9): A novel potent dual PI3K/mTOR inhibitor for cancer therapy Sun, Xin

129 C p.
artikel
22 Design, synthesis, spectroscopic characterization, in vitro tyrosinase inhibition, antioxidant evaluation, in silico and kinetic studies of substituted indole-carbohydrazides Iraji, Aida

129 C p.
artikel
23 Development of a nitroreductase-dependent theranostic payload for antibody-drug conjugate Su, Zheng

129 C p.
artikel
24 Development of fluorescent dual-FRET probe for simultaneous detection of caspase-8 and caspase-9 activities and their relative quantification Porubský, Martin

129 C p.
artikel
25 Development of novel cyanopyridines as PIM-1 kinase inhibitors with potent anti-prostate cancer activity: Synthesis, biological evaluation, nanoparticles formulation and molecular dynamics simulation Ibrahim, Mona H.

129 C p.
artikel
26 Development of novel nitric oxide-releasing quinolinedione/furoxan hybrids as NQO1 inhibitors for intervention of drug-resistanthepatocellular cancer Zhang, Xiaoyan

129 C p.
artikel
27 Discovery of a potent EGFR and ALK dual mutation inhibitor containing N-(3-((4-((2-(cyclopropylsulfinyl)phenyl)amino)pyrimidin-2-yl)amino) phenyl)acrylamide scaffold Li, Wei

129 C p.
artikel
28 Discovery of bicyclic polyprenylated acylphloroglucinols from Hypericum himalaicum with glucose transporter 4 translocation activity Cheng, Haitao

129 C p.
artikel
29 Discovery of novel β-carboline-1,2,3-triazole hybrids as AChE/GSK-3β dual inhibitors for Alzheimer's disease treatment Liu, Wenjie

129 C p.
artikel
30 Discovery of novel dihydropyrazole-stilbene derivatives for ameliorating heart failure through modulation of p38/NF-κB signaling pathway Liu, Zhigang

129 C p.
artikel
31 Discovery of novel heterocyclic derivatives as potential glycogen phosphorylase inhibitors with a cardioprotective effect Yan, Zhiwei

129 C p.
artikel
32 Discovery of novel 1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors with hypouricemic effects Yang, Yajun

129 C p.
artikel
33 Discovery of 12β-oxygenated oleanolic acid alkyl esters as potent and selective FXR modulators exhibiting hyperglycemia amelioration in vivo Wang, Shaorong

129 C p.
artikel
34 Discovery of potent and selective dual cholinesterases and β-secretase inhibitors in pomegranate as a treatment for Alzheimer’s disease Yousof Ali, Md.

129 C p.
artikel
35 Discovery of selective HDAC6 inhibitors capped by flavonoid or flavonoid-analogous moieties as anti-cancer therapeutics simultaneously harboring anti-proliferative and immunomodulatory activities He, Ge

129 C p.
artikel
36 Discovery, optimization and evaluation of isothiazolo[5,4-b]pyridine derivatives as RIPK1 inhibitors with potent in vivo anti-SIRS activity Hao, Yongjin

129 C p.
artikel
37 Dual-modal polypeptide-containing contrast agents for magnetic resonance/fluorescence imaging Zheng, Si-Yao

129 C p.
artikel
38 Editorial Board
129 C p.
artikel
39 Ethyl-4-(aryl)-6-methyl-2-(oxo/thio)-3,4-dihydro-1H-pyrimidine-5-carboxylates: Silica supported bismuth(III)triflate catalyzed synthesis and antioxidant activity Gajjala, Raghavendra Reddy

129 C p.
artikel
40 Eucarbwenstols A–H, eight novel compounds from Eucalyptus robusta prevents MPC-5 injury via ROS modulation and regulation of mitochondrial membrane potential Chen, Ting

129 C p.
artikel
41 Exploring the anti-influenza virus activity of novel triptolide derivatives targeting nucleoproteins Jiang, Na

129 C p.
artikel
42 Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands Arifi, Silvia

129 C p.
artikel
43 Guaiane-type sesquiterpenoids with various ring skeletons from Daphne bholua uncovered by molecular networking and structural revisions of previously reported analogues Dong, Shu-Hui

129 C p.
artikel
44 HDAC/JAK dual target inhibitors of cancer-related targets: The success of nonclearable linked pharmacophore mode Zhao, Liyun

129 C p.
artikel
45 Hemicyanine-based pH-responsive probes for rapid hypoxia detection in cancer cells Wangngae, Sirilak

129 C p.
artikel
46 Human dihydrofolate reductase inhibition effect of 1-Phenylpyrazolo[3,4–d]pyrimidines: Synthesis, antitumor evaluation and molecular modeling study Salem, Ibrahim M.

129 C p.
artikel
47 Hydantoin based dual inhibitors of ALR2 and PARP-1: Design, synthesis, in-vitro and in-vivo evaluation Kumar, Manoj

129 C p.
artikel
48 Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC Minnelli, Cristina

129 C p.
artikel
49 Identification of thienopyrimidine glycinates as selective inhibitors for h-NTPDases Begum, Zahra

129 C p.
artikel
50 Isolation and synthesis of rocaglaol derivatives by inhibiting Wnt/β-catenin and MAPK signaling pathways against colorectal cancer Li, Yanan

129 C p.
artikel
51 1,2-Isoselenazol-3(2H)-one derivatives as NDM-1 inhibitors displaying synergistic antimicrobial effects with meropenem on NDM-1 producing clinical isolates Yue, Kairui

129 C p.
artikel
52 Issue TOC
129 C p.
artikel
53 Lactate dehydrogenase A inhibitors with a 2,8-dioxabicyclo[3.3.1]nonane scaffold: A contribution to molecular therapies for primary hyperoxalurias Alejo-Armijo, Alfonso

129 C p.
artikel
54 Mahanimbine isolated from Murraya koenigii inhibits P-glycoprotein involved in lung cancer chemoresistance Mondal, Priya

129 C p.
artikel
55 Mesenchymal stem cells-derived HIF-1α-overexpressed extracellular vesicles ameliorate hypoxia-induced pancreatic β cell apoptosis and senescence through activating YTHDF1-mediated protective autophagy Fang, Jiali

129 C p.
artikel
56 Mitochondria targeted dual-fluorescent probe for bio-imaging viscosity and F− with different fluorescence signals Dhiman, Sukhvinder

129 C p.
artikel
57 Natural carbazole alkaloid murrayafoline A displays potent anti-neuroinflammatory effect by directly targeting transcription factor Sp1 in LPS-induced microglial cells Li, Chao-Hua

129 C p.
artikel
58 Natural phenylethanoid glycosides diuretics derived from Lagopsis supina: Biological activity, mechanism, molecular docking, and structure-activity relationship Yang, Li

129 C p.
artikel
59 New anti-inflammatory and non-cytotoxic metabolites of methylstenbolone obtained by microbial transformation Aamer, Muhammad

129 C p.
artikel
60 New polyphenolic glycosides from the stems of Caesalpinia cucullata and their inhibitory effect on methicillin-resistant Staphylococcus aureus with different ways Jing, Wenhua

129 C p.
artikel
61 Nicotinonitrile-derived apoptotic inducers: Design, synthesis, X-ray crystal structure and Pim kinase inhibition Aboukhatwa, Shaimaa M.

129 C p.
artikel
62 Nitroreductase-induced bioorthogonal ligation for prodrug activation: A traceless strategy for cancer-specific imaging and therapy Hu, Liangkui

129 C p.
artikel
63 Novel chiral Schiff base Palladium(II), Nickel(II), Copper(II) and Iron(II) complexes: Synthesis, characterization, anticancer activity and molecular docking studies Basaran, Eyüp

129 C p.
artikel
64 Novel diaryl ether derivatives as InhA inhibitors: Design, synthesis and antimycobacterial activity Abdelaziz, Ola A.

129 C p.
artikel
65 Novel 1,3-diaryl pyrazole derivatives bearing methylsulfonyl moiety: Design, synthesis, molecular docking and dynamics, with dual activities as anti-inflammatory and anticancer agents through selectively targeting COX-2 Shaker, Ahmed M.M.

129 C p.
artikel
66 Novel 5,6-diphenyl-1,2,4-triazine-3-thiol derivatives as dual COX-2/5-LOX inhibitors devoid of cardiotoxicity Saraf, Poorvi

129 C p.
artikel
67 Novel spirooxindole based benzimidazole scaffold: In vitro, nanoformulation and in vivo studies on anticancer and antimetastatic activity of breast adenocarcinoma Barakat, Assem

129 C p.
artikel
68 Novel synthesis naringenin-benzyl piperazine derivatives prevent glioblastoma invasion by inhibiting the hypoxia-induced IL6/JAK2/STAT3 axis and activating caspase-dependent apoptosis Zaim, Ömer

129 C p.
artikel
69 Optimization of a cell surface vimentin binding peptoid to extract antagonist effect on lung cancer cells Zhang, Haowen

129 C p.
artikel
70 Peptide inhibitors of angiotensin-I converting enzyme based on angiotensin (1–7) with selectivity for the C-terminal domain da Silva, Rogerio L.

129 C p.
artikel
71 Photodynamic antitumor activity of Gallium(III) and Phosphorus(V) complexes of trimethoxyl A2B triaryl corrole Yang, Wu

129 C p.
artikel
72 Prospect of ULK1 modulators in targeting regulatory T cells Park, Youngjun

129 C p.
artikel
73 Pseudoamaolides A-O, anti-inflammatory triterpene spiroketal lactones from seeds of Pseudolarix amabilis Zhu, Yuxun

129 C p.
artikel
74 Rational development of an ESIPT-based fluorescent probe with large Stokes shift for imaging of hydrogen sulfide in live cells Du, Yuting

129 C p.
artikel
75 Recent advances in transition metal-catalyzed reactions of chloroquinoxalines: Applications in bioorganic chemistry Sujeevan Reddy, Gangireddy

129 C p.
artikel
76 Repurposing N-hydroxy thienopyrimidine-2,4-diones (HtPD) as inhibitors of human cytomegalovirus pUL89 endonuclease: Synthesis and biological characterization He, Tianyu

129 C p.
artikel
77 SAR study of oxidative DIMs analogs targeting the Nur77-mediated apoptotic pathway of cancer cells Chen, Xiaohui

129 C p.
artikel
78 SAR study on Novel truxillic acid monoester-Based inhibitors of fatty acid binding proteins as Next-Generation antinociceptive agents Wang, Hehe

129 C p.
artikel
79 Sesquiterpene lactones from Elephantopus scaber exhibit cytotoxic effects on glioma cells by targeting GSTP1 Yan, Qiu-Lin

129 C p.
artikel
80 Sonochemical synthesis and biological evaluation of isoquinolin-1(2H)-one/isoindolin-1-one derivatives: Discovery of a positive ago-allosteric modulator (PAAM) of 5HT2CR Sandeep Kumar, Jetta

129 C p.
artikel
81 Structure based design and synthesis of 3-(7-nitro-3-oxo-3,4-dihydroquinoxalin-2-yl)propanehydrazide derivatives as novel bacterial DNA-gyrase inhibitors: In-vitro, In-vivo, In-silico and SAR studies Saleh, Marwa A.

129 C p.
artikel
82 Structure-based screening and biological validation of the anti-thrombotic drug-dicoumarol as a novel and potent PPARγ-modulating ligand Ma, Lei

129 C p.
artikel
83 3-Substituted-2,3-Dihydrothiazole as a promising scaffold to design EGFR inhibitors El-Haggar, Radwan

129 C p.
artikel
84 Substituted phenethylamine-based β-lactam derivatives: Antimicrobial, anticancer, and β-lactamase inhibitory properties Yildirim, Merve

129 C p.
artikel
85 Synthesis and biological evaluation of novel dialkyl (4-amino-5H-chromeno[2,3-d]pyrimidin-5-yl)phosphonates Sreelakshmi, Poola

129 C p.
artikel
86 Synthesis and in vivo evaluation of new steviol derivatives that protect against cardiomyopathy by inhibiting ferroptosis Xu, Chao

129 C p.
artikel
87 Synthetic access to syn-functionalised chiral hydroxy pyrrolidines and pyrrolidones: Evaluation of α-glucosidase inhibition activity, docking studies and pharmacokinetics prediction Mhaldar, Shashank N.

129 C p.
artikel
88 Targeting neuronal calcium channels and GSK3β for Alzheimer’s disease with naturally-inspired Diels-Alder adducts Bisi, Alessandra

129 C p.
artikel
89 Targeting the kinetics mechanism of AMPA receptor inhibition by 2-oxo-3H-benzoxazole derivatives Qneibi, Mohammad

129 C p.
artikel
90 The Design, Structure–Activity, and kinetic studies of 3-Benzyl-5-oxa-1,2,3,4-Tetrahydro-2H-chromeno-(3,4-c)pyridin-8-yl sulfamates as Steroid sulfatase inhibitors Chang, Chiao-Nien

129 C p.
artikel
91 The multifaceted roles of peptides in “always-on” near-infrared fluorescent probes for tumor imaging Xu, Haiwei

129 C p.
artikel
92 Therapeutic potential of phospho-thiadiazole derivatives as anti-glioblastoma agents: synthesis, biological assessment and computational study Gholivand, Khodayar

129 C p.
artikel
93 Thiol-Michael addition based conjugate for glutathione activation and release Liu, Zhengkun

129 C p.
artikel
94 Versicotide G suppresses osteoclastogenesis and prevents osteolysis Zhang, He

129 C p.
artikel
95 Water-soluble dual lysosome/mitochondria-targeted fluorescent probe for detection of SO2 in water, food, herb, and live cells Dong, Zhenming

129 C p.
artikel
                             95 gevonden resultaten
 
 Koninklijke Bibliotheek - Nationale Bibliotheek van Nederland