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                             95 results found
no title author magazine year volume issue page(s) type
1 Acriflavine and proflavine hemisulfate as potential antivirals by targeting Mpro Liang, Jing

129 C p.
article
2 Allyl phenyl selenides as H2O2 acceptors to develop ROS-responsive theranostic prodrugs Yang, Xue-Yan

129 C p.
article
3 Anti-inflammatory butanolides and lignanoids from the root of Machilus zuihoensis var. mushaensis Yang, Shuen-Shin

129 C p.
article
4 Anti-proliferative tirucallane triterpenoids from gum resin of Boswellia sacra Zhang, Bingyang

129 C p.
article
5 Assessing p-tolyloxy-1,3,4-oxadiazole acetamides as lipoxygenase inhibitors assisted by in vitro and in silico studies Bashir, Bushra

129 C p.
article
6 Biosynthesis, characterization and biomedical potential of Arthrospira indica SOSA-4 mediated SeNPs Afzal, Bushra

129 C p.
article
7 Callicarpnoids A–C, structurally intriguing ent-Clerodane diterpenoid dimers with cytotoxicity against MCF-7 and HCT-116 cell lines from Callicarpa arborea Roxb Cheng, Bin

129 C p.
article
8 Cationic RGD peptidomimetic nanoconjugates as effective tumor targeting gene delivery vectors with antimicrobial potential Ahmadi, Zeba

129 C p.
article
9 CC1007, a small molecular compound, suppresses multiple myeloma via upregulation of Nur77 Zhu, Shicong

129 C p.
article
10 Chemical synthesis of fluorinated and iodinated 17β-HSD3 inhibitors and evaluation for imaging prostate cancer tumors and tissue biodistribution Poirier, Donald

129 C p.
article
11 Construction of an in vivo NIR fluorescent probe for revealing the correlation between inflammation and mitochondrial hydrogen sulfide and viscosity Cui, Yali

129 C p.
article
12 Design and synthesis of N-(1-(6-(substituted phenyl)-pyridazin-3-yl)-piperidine-3-yl)-amine derivatives as JMJD6 inhibitors Qian, Yuqing

129 C p.
article
13 Design, synthesis and antitumor activity evaluation of novel indole acrylamide derivatives as IMPDH inhibitors Jia, Hong-Wei

129 C p.
article
14 Design, synthesis and biological evaluation of 2-aminopyridine derivatives as USP7 inhibitors Xu, Xiaoming

129 C p.
article
15 Design, synthesis and biological evaluation of dehydroabietic acid derivative as potent vasodilatory agents Wu, Dan

129 C p.
article
16 Design, synthesis, and biological evaluation of novel sulfamoylbenzamide derivatives as HBV capsid assembly modulators Wang, Shuo

129 C p.
article
17 Design, synthesis and biological evaluation of novel tumor hypoxia-activated EGFR tyrosine kinase inhibitors Jia, Tingting

129 C p.
article
18 Design, synthesis and biological evaluation of pyranocarbazole derivatives against Alzheimer’s disease, with antioxidant, neuroprotective and cognition enhancing properties Zang, Yingda

129 C p.
article
19 Design, synthesis, and in vitro evaluation of novel antifungal triazoles containing substituted 1,2,3-triazole-methoxyl side chains Xie, Fei

129 C p.
article
20 Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities Ahmed, Asmaa H.H.

129 C p.
article
21 Design, synthesis and pharmacological evaluation of 2-arylurea-1,3,5-triazine derivative (XIN-9): A novel potent dual PI3K/mTOR inhibitor for cancer therapy Sun, Xin

129 C p.
article
22 Design, synthesis, spectroscopic characterization, in vitro tyrosinase inhibition, antioxidant evaluation, in silico and kinetic studies of substituted indole-carbohydrazides Iraji, Aida

129 C p.
article
23 Development of a nitroreductase-dependent theranostic payload for antibody-drug conjugate Su, Zheng

129 C p.
article
24 Development of fluorescent dual-FRET probe for simultaneous detection of caspase-8 and caspase-9 activities and their relative quantification Porubský, Martin

129 C p.
article
25 Development of novel cyanopyridines as PIM-1 kinase inhibitors with potent anti-prostate cancer activity: Synthesis, biological evaluation, nanoparticles formulation and molecular dynamics simulation Ibrahim, Mona H.

129 C p.
article
26 Development of novel nitric oxide-releasing quinolinedione/furoxan hybrids as NQO1 inhibitors for intervention of drug-resistanthepatocellular cancer Zhang, Xiaoyan

129 C p.
article
27 Discovery of a potent EGFR and ALK dual mutation inhibitor containing N-(3-((4-((2-(cyclopropylsulfinyl)phenyl)amino)pyrimidin-2-yl)amino) phenyl)acrylamide scaffold Li, Wei

129 C p.
article
28 Discovery of bicyclic polyprenylated acylphloroglucinols from Hypericum himalaicum with glucose transporter 4 translocation activity Cheng, Haitao

129 C p.
article
29 Discovery of novel β-carboline-1,2,3-triazole hybrids as AChE/GSK-3β dual inhibitors for Alzheimer's disease treatment Liu, Wenjie

129 C p.
article
30 Discovery of novel dihydropyrazole-stilbene derivatives for ameliorating heart failure through modulation of p38/NF-κB signaling pathway Liu, Zhigang

129 C p.
article
31 Discovery of novel heterocyclic derivatives as potential glycogen phosphorylase inhibitors with a cardioprotective effect Yan, Zhiwei

129 C p.
article
32 Discovery of novel 1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors with hypouricemic effects Yang, Yajun

129 C p.
article
33 Discovery of 12β-oxygenated oleanolic acid alkyl esters as potent and selective FXR modulators exhibiting hyperglycemia amelioration in vivo Wang, Shaorong

129 C p.
article
34 Discovery of potent and selective dual cholinesterases and β-secretase inhibitors in pomegranate as a treatment for Alzheimer’s disease Yousof Ali, Md.

129 C p.
article
35 Discovery of selective HDAC6 inhibitors capped by flavonoid or flavonoid-analogous moieties as anti-cancer therapeutics simultaneously harboring anti-proliferative and immunomodulatory activities He, Ge

129 C p.
article
36 Discovery, optimization and evaluation of isothiazolo[5,4-b]pyridine derivatives as RIPK1 inhibitors with potent in vivo anti-SIRS activity Hao, Yongjin

129 C p.
article
37 Dual-modal polypeptide-containing contrast agents for magnetic resonance/fluorescence imaging Zheng, Si-Yao

129 C p.
article
38 Editorial Board
129 C p.
article
39 Ethyl-4-(aryl)-6-methyl-2-(oxo/thio)-3,4-dihydro-1H-pyrimidine-5-carboxylates: Silica supported bismuth(III)triflate catalyzed synthesis and antioxidant activity Gajjala, Raghavendra Reddy

129 C p.
article
40 Eucarbwenstols A–H, eight novel compounds from Eucalyptus robusta prevents MPC-5 injury via ROS modulation and regulation of mitochondrial membrane potential Chen, Ting

129 C p.
article
41 Exploring the anti-influenza virus activity of novel triptolide derivatives targeting nucleoproteins Jiang, Na

129 C p.
article
42 Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands Arifi, Silvia

129 C p.
article
43 Guaiane-type sesquiterpenoids with various ring skeletons from Daphne bholua uncovered by molecular networking and structural revisions of previously reported analogues Dong, Shu-Hui

129 C p.
article
44 HDAC/JAK dual target inhibitors of cancer-related targets: The success of nonclearable linked pharmacophore mode Zhao, Liyun

129 C p.
article
45 Hemicyanine-based pH-responsive probes for rapid hypoxia detection in cancer cells Wangngae, Sirilak

129 C p.
article
46 Human dihydrofolate reductase inhibition effect of 1-Phenylpyrazolo[3,4–d]pyrimidines: Synthesis, antitumor evaluation and molecular modeling study Salem, Ibrahim M.

129 C p.
article
47 Hydantoin based dual inhibitors of ALR2 and PARP-1: Design, synthesis, in-vitro and in-vivo evaluation Kumar, Manoj

129 C p.
article
48 Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC Minnelli, Cristina

129 C p.
article
49 Identification of thienopyrimidine glycinates as selective inhibitors for h-NTPDases Begum, Zahra

129 C p.
article
50 Isolation and synthesis of rocaglaol derivatives by inhibiting Wnt/β-catenin and MAPK signaling pathways against colorectal cancer Li, Yanan

129 C p.
article
51 1,2-Isoselenazol-3(2H)-one derivatives as NDM-1 inhibitors displaying synergistic antimicrobial effects with meropenem on NDM-1 producing clinical isolates Yue, Kairui

129 C p.
article
52 Issue TOC
129 C p.
article
53 Lactate dehydrogenase A inhibitors with a 2,8-dioxabicyclo[3.3.1]nonane scaffold: A contribution to molecular therapies for primary hyperoxalurias Alejo-Armijo, Alfonso

129 C p.
article
54 Mahanimbine isolated from Murraya koenigii inhibits P-glycoprotein involved in lung cancer chemoresistance Mondal, Priya

129 C p.
article
55 Mesenchymal stem cells-derived HIF-1α-overexpressed extracellular vesicles ameliorate hypoxia-induced pancreatic β cell apoptosis and senescence through activating YTHDF1-mediated protective autophagy Fang, Jiali

129 C p.
article
56 Mitochondria targeted dual-fluorescent probe for bio-imaging viscosity and F− with different fluorescence signals Dhiman, Sukhvinder

129 C p.
article
57 Natural carbazole alkaloid murrayafoline A displays potent anti-neuroinflammatory effect by directly targeting transcription factor Sp1 in LPS-induced microglial cells Li, Chao-Hua

129 C p.
article
58 Natural phenylethanoid glycosides diuretics derived from Lagopsis supina: Biological activity, mechanism, molecular docking, and structure-activity relationship Yang, Li

129 C p.
article
59 New anti-inflammatory and non-cytotoxic metabolites of methylstenbolone obtained by microbial transformation Aamer, Muhammad

129 C p.
article
60 New polyphenolic glycosides from the stems of Caesalpinia cucullata and their inhibitory effect on methicillin-resistant Staphylococcus aureus with different ways Jing, Wenhua

129 C p.
article
61 Nicotinonitrile-derived apoptotic inducers: Design, synthesis, X-ray crystal structure and Pim kinase inhibition Aboukhatwa, Shaimaa M.

129 C p.
article
62 Nitroreductase-induced bioorthogonal ligation for prodrug activation: A traceless strategy for cancer-specific imaging and therapy Hu, Liangkui

129 C p.
article
63 Novel chiral Schiff base Palladium(II), Nickel(II), Copper(II) and Iron(II) complexes: Synthesis, characterization, anticancer activity and molecular docking studies Basaran, Eyüp

129 C p.
article
64 Novel diaryl ether derivatives as InhA inhibitors: Design, synthesis and antimycobacterial activity Abdelaziz, Ola A.

129 C p.
article
65 Novel 1,3-diaryl pyrazole derivatives bearing methylsulfonyl moiety: Design, synthesis, molecular docking and dynamics, with dual activities as anti-inflammatory and anticancer agents through selectively targeting COX-2 Shaker, Ahmed M.M.

129 C p.
article
66 Novel 5,6-diphenyl-1,2,4-triazine-3-thiol derivatives as dual COX-2/5-LOX inhibitors devoid of cardiotoxicity Saraf, Poorvi

129 C p.
article
67 Novel spirooxindole based benzimidazole scaffold: In vitro, nanoformulation and in vivo studies on anticancer and antimetastatic activity of breast adenocarcinoma Barakat, Assem

129 C p.
article
68 Novel synthesis naringenin-benzyl piperazine derivatives prevent glioblastoma invasion by inhibiting the hypoxia-induced IL6/JAK2/STAT3 axis and activating caspase-dependent apoptosis Zaim, Ömer

129 C p.
article
69 Optimization of a cell surface vimentin binding peptoid to extract antagonist effect on lung cancer cells Zhang, Haowen

129 C p.
article
70 Peptide inhibitors of angiotensin-I converting enzyme based on angiotensin (1–7) with selectivity for the C-terminal domain da Silva, Rogerio L.

129 C p.
article
71 Photodynamic antitumor activity of Gallium(III) and Phosphorus(V) complexes of trimethoxyl A2B triaryl corrole Yang, Wu

129 C p.
article
72 Prospect of ULK1 modulators in targeting regulatory T cells Park, Youngjun

129 C p.
article
73 Pseudoamaolides A-O, anti-inflammatory triterpene spiroketal lactones from seeds of Pseudolarix amabilis Zhu, Yuxun

129 C p.
article
74 Rational development of an ESIPT-based fluorescent probe with large Stokes shift for imaging of hydrogen sulfide in live cells Du, Yuting

129 C p.
article
75 Recent advances in transition metal-catalyzed reactions of chloroquinoxalines: Applications in bioorganic chemistry Sujeevan Reddy, Gangireddy

129 C p.
article
76 Repurposing N-hydroxy thienopyrimidine-2,4-diones (HtPD) as inhibitors of human cytomegalovirus pUL89 endonuclease: Synthesis and biological characterization He, Tianyu

129 C p.
article
77 SAR study of oxidative DIMs analogs targeting the Nur77-mediated apoptotic pathway of cancer cells Chen, Xiaohui

129 C p.
article
78 SAR study on Novel truxillic acid monoester-Based inhibitors of fatty acid binding proteins as Next-Generation antinociceptive agents Wang, Hehe

129 C p.
article
79 Sesquiterpene lactones from Elephantopus scaber exhibit cytotoxic effects on glioma cells by targeting GSTP1 Yan, Qiu-Lin

129 C p.
article
80 Sonochemical synthesis and biological evaluation of isoquinolin-1(2H)-one/isoindolin-1-one derivatives: Discovery of a positive ago-allosteric modulator (PAAM) of 5HT2CR Sandeep Kumar, Jetta

129 C p.
article
81 Structure based design and synthesis of 3-(7-nitro-3-oxo-3,4-dihydroquinoxalin-2-yl)propanehydrazide derivatives as novel bacterial DNA-gyrase inhibitors: In-vitro, In-vivo, In-silico and SAR studies Saleh, Marwa A.

129 C p.
article
82 Structure-based screening and biological validation of the anti-thrombotic drug-dicoumarol as a novel and potent PPARγ-modulating ligand Ma, Lei

129 C p.
article
83 3-Substituted-2,3-Dihydrothiazole as a promising scaffold to design EGFR inhibitors El-Haggar, Radwan

129 C p.
article
84 Substituted phenethylamine-based β-lactam derivatives: Antimicrobial, anticancer, and β-lactamase inhibitory properties Yildirim, Merve

129 C p.
article
85 Synthesis and biological evaluation of novel dialkyl (4-amino-5H-chromeno[2,3-d]pyrimidin-5-yl)phosphonates Sreelakshmi, Poola

129 C p.
article
86 Synthesis and in vivo evaluation of new steviol derivatives that protect against cardiomyopathy by inhibiting ferroptosis Xu, Chao

129 C p.
article
87 Synthetic access to syn-functionalised chiral hydroxy pyrrolidines and pyrrolidones: Evaluation of α-glucosidase inhibition activity, docking studies and pharmacokinetics prediction Mhaldar, Shashank N.

129 C p.
article
88 Targeting neuronal calcium channels and GSK3β for Alzheimer’s disease with naturally-inspired Diels-Alder adducts Bisi, Alessandra

129 C p.
article
89 Targeting the kinetics mechanism of AMPA receptor inhibition by 2-oxo-3H-benzoxazole derivatives Qneibi, Mohammad

129 C p.
article
90 The Design, Structure–Activity, and kinetic studies of 3-Benzyl-5-oxa-1,2,3,4-Tetrahydro-2H-chromeno-(3,4-c)pyridin-8-yl sulfamates as Steroid sulfatase inhibitors Chang, Chiao-Nien

129 C p.
article
91 The multifaceted roles of peptides in “always-on” near-infrared fluorescent probes for tumor imaging Xu, Haiwei

129 C p.
article
92 Therapeutic potential of phospho-thiadiazole derivatives as anti-glioblastoma agents: synthesis, biological assessment and computational study Gholivand, Khodayar

129 C p.
article
93 Thiol-Michael addition based conjugate for glutathione activation and release Liu, Zhengkun

129 C p.
article
94 Versicotide G suppresses osteoclastogenesis and prevents osteolysis Zhang, He

129 C p.
article
95 Water-soluble dual lysosome/mitochondria-targeted fluorescent probe for detection of SO2 in water, food, herb, and live cells Dong, Zhenming

129 C p.
article
                             95 results found
 
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