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                             78 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A bifunctional fluorescence probe for dual-channel detecting of mitochondrial viscosity and endogenous/exogenous peroxynitrite Li, Minglu

119 C p.
artikel
2 A coumarin-based fluorescent probe for specific detection of cysteine in the lysosome of living cells Lu, Guowei

119 C p.
artikel
3 An abiotic fluorescent probe for the detection and quantification of carcinoembryonic antigen Lee, Jung-Seop

119 C p.
artikel
4 A near-infrared, colorimetric and ratiometric fluorescent sensor with high sensitivity to hydrogen peroxide and viscosity for solutions detection and imaging living cells Liu, Daili

119 C p.
artikel
5 A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer Lier, Svenja

119 C p.
artikel
6 Antibacterial, antibiofilm, anti-inflammatory, and wound healing effects of nanoscale multifunctional cationic alternating copolymers Hooshmand, Seyyed Emad

119 C p.
artikel
7 Anti-inflammatory, ulcerogenic and platelet activation evaluation of novel 1,4-diaryl-1,2,3-triazole neolignan-celecoxib hybrids Felipe, Josyelen L.

119 C p.
artikel
8 Baicalin ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice through modulating skin barrier function, gut microbiota and JAK/STAT pathway Wang, Lan

119 C p.
artikel
9 Biocatalytic one pot three component approach: Facile synthesis, characterization, molecular modelling and hypoglycemic studies of new thiazolidinedione festooned quinoline analogues catalyzed by alkaline protease from Aspergillus niger Angajala, Gangadhara

119 C p.
artikel
10 Chamaejasmenin E from Stellera chamaejasme induces apoptosis of hepatocellular carcinoma cells by targeting c-Met in vitro and in vivo Yu, Xiao-Qi

119 C p.
artikel
11 Click ferrocenyl-erlotinib conjugates active against erlotinib-resistant non-small cell lung cancer cells in vitro Biegański, Przemysław

119 C p.
artikel
12 Construction of synergistic pH/H2O2-responsive prodrug for prolonging blood circulation and accelerating cellular internalization Liu, Jun

119 C p.
artikel
13 Corrigendum to “Daphnegiravone D from Daphne giraldii induces cell death by targeting ATR in Hep3B cells” [Bioorg. Chem. 110 (2021) 104802] Shang, Xin-Yue

119 C p.
artikel
14 C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity Rui, Ruo-Mei

119 C p.
artikel
15 Cyclometalated Ru(II)-isoquinoline complexes overcome cisplatin resistance of A549/DDP cells by downregulation of Nrf2 via Akt/GSK-3β/Fyn pathway Chen, Lanmei

119 C p.
artikel
16 Degrading FLT3-ITD protein by proteolysis targeting chimera (PROTAC) Chen, Yong

119 C p.
artikel
17 Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives Chen, Wenming

119 C p.
artikel
18 Design and synthesis of fluorinated peptides for analysis of fluorous effects on the interconversion of polyproline helices Li, Meng-Che

119 C p.
artikel
19 Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates Ghanim, Amany M.

119 C p.
artikel
20 Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy Gangar, Mukesh

119 C p.
artikel
21 Design, synthesis, and evaluation of novel pyridone derivatives as potent BRD4 inhibitors for the potential treatment of prostate cancer Jiang, Wenhua

119 C p.
artikel
22 Design, synthesis and SAR study of Fluorine-containing 3rd-generation taxoids Wang, Changwei

119 C p.
artikel
23 Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new anti-vitiligo compounds Yang, Bi-juan

119 C p.
artikel
24 Design, synthesis, biological screening and molecular docking studies of novel multifunctional 1,4-di (aryl/heteroaryl) substituted piperazine derivatives as potential antitubercular and antimicrobial agents Mekonnen Sanka, Bruktawit

119 C p.
artikel
25 Design, synthesis, in vitro antiproliferative evaluation and GSK-3β kinase inhibition of a new series of pyrimidin-4-one based amide conjugates Khan, Imran

119 C p.
artikel
26 Development of novel indolin-2-one derivative incorporating thiazole moiety as DHFR and quorum sensing inhibitors: Synthesis, antimicrobial, and antibiofilm activities with molecular modelling study Alzahrani, Abdullah Y.

119 C p.
artikel
27 Discovery of 7-alkyloxy- [1,2,4] triazolo[1,5-a] pyrimidine derivatives as selective positive modulators of GABAA1 and GABAA4 receptors with potent antiepileptic activity Wu, Jun

119 C p.
artikel
28 Discovery of linear unnatural peptides as potent mutant isocitrate dehydrogenase 1 inhibitors by Ugi reaction Zhou, Xuechen

119 C p.
artikel
29 Discovery of N-(2-benzyl-4-oxochroman-7-yl)-2-(5-(ethylsulfonyl) pyridin-2-yl) acetamide (b12) as a potent, selective, and orally available novel retinoic acid receptor-related orphan receptor γt inverse agonist Chen, Lei

119 C p.
artikel
30 Discovery of N-(1,3,4-thiadiazol-2-yl)benzamide derivatives containing a 6,7-methoxyquinoline structure as novel EGFR/HER-2 dual-target inhibitors against cancer growth and angiogenesis Li, Xin-yang

119 C p.
artikel
31 Discovery of pyrido[3,4-b]indol-1-one derivatives as novel non-covalent Bruton’s tyrosine kinase (BTK) inhibitors Dou, Dou

119 C p.
artikel
32 Discovery of urease inhibitory effect of sulfamate derivatives: Biological and computational studies Zaib, Sumera

119 C p.
artikel
33 Diterpenoids from Euphorbia helioscopia and their enhancement of NK cell-mediated killing of NSCLC cells Mu, Hong-yan

119 C p.
artikel
34 Downsizing antibodies: Towards complementarity-determining region (CDR)-based peptide mimetics Van holsbeeck, Kevin

119 C p.
artikel
35 Editorial Board
119 C p.
artikel
36 Euphoesulatin A prevents osteoclast differentiation and bone loss via inhibiting RANKL-induced ROS production and NF-κB and MAPK signal pathways Zhang, Yu-ting

119 C p.
artikel
37 Exploring the binding mode of ester-based cationic gemini surfactants with calf thymus DNA: A detailed physicochemical, spectroscopic and theoretical study Akram, Mohd

119 C p.
artikel
38 Hollongdione arylidene derivatives induce antiproliferative activity against melanoma and breast cancer through pro-apoptotic and antiangiogenic mechanisms Smirnova, Irina

119 C p.
artikel
39 H2O2-Responsive amphiphilic polymer with aggregation-induced emission (AIE) for DOX delivery and tumor therapy Liang, Ya-Xuan

119 C p.
artikel
40 Identification and synthesis of selective cholesterol esterase inhibitor using dynamic combinatorial chemistry Zhao, Shuang

119 C p.
artikel
41 Identification of NLRP3 as a covalent target of 1,6-O,O-diacetylbritannilactone against neuroinflammation by quantitative thiol reactivity profiling (QTRP) Wang, Min-Ran

119 C p.
artikel
42 3-Imino derivative-sulfahydantoins: Synthesis, in vitro antibacterial and cytotoxic activities and their DNA interactions Başkan, Ceren

119 C p.
artikel
43 Indoles and 1-(3-(benzyloxy)benzyl)piperazines: Reversible and selective monoamine oxidase B inhibitors identified by screening an in-house compound library Knez, Damijan

119 C p.
artikel
44 Isolation, identification, and activity evaluation of antioxidant components from Inula viscosa: A bioguided approach Zeouk, Ikrame

119 C p.
artikel
45 Issue TOC
119 C p.
artikel
46 Membrane mechanism of temporin-1CEc, an antimicrobial peptide isolated from the skin secretions of Rana chensinensis, and its systemic analogs Ji, Fangyu

119 C p.
artikel
47 Multifunctional fluorescent probes for high-throughput characterization of hexosaminidase enzyme activity Wang, Shaochi

119 C p.
artikel
48 Natural-product-inspired design and synthesis of two series of compounds active against Trypanosoma cruzi: Insights into structure–activity relationship, toxicity, and mechanism of action da Rosa, Rafael

119 C p.
artikel
49 New aniline derivatives from the volva of Phallus rubrovolvatus and their anti-inflammatory activity Lv, Jianhua

119 C p.
artikel
50 New enantiomeric lignans and new meroterpenoids with nitric oxide release inhibitory activity from Piper puberulum Zheng, Yuan-kun

119 C p.
artikel
51 Novel synthesis of antibacterial pyrone derivatives using kinetics and mechanism of oxidation of azithromycin by alkaline permanganate Ibrahim, Samia M.

119 C p.
artikel
52 Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and molecular dynamics simulation Hasan, Aso Hameed

119 C p.
artikel
53 Ortho-hydroxy bioactive schiff base compounds: Design, comprehensive characterization, photophysical properties and elucidation of antimicrobial and mutagenic potentials Nıbras Qader Qader, Israa

119 C p.
artikel
54 Platinum(II) and Copper(II) complexes of asymmetric halogen-substituted [NNʹO] ligands: Synthesis, characterization, structural investigations and antiproliferative activity Amiri Rudbari, Hadi

119 C p.
artikel
55 Rational design and synthesis of Oreoch-2 analogues as efficient broad-spectrum antimicrobial peptides Zhang, Na

119 C p.
artikel
56 Recent advances in the synthesis of naturally occurring tetronic acids Princiotto, Salvatore

119 C p.
artikel
57 Structural optimizations and bioevaluation of N-substituted acridone derivatives as strong topoisomerase II inhibitors Li, Zhi-Ying

119 C p.
artikel
58 Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity Ragab, Mahmoud A.

119 C p.
artikel
59 Structure-Based design of Marine-derived Meridianin C derivatives as glycogen synthase kinase 3β inhibitors with improved oral bioavailability: From aminopyrimidyl-indoles to the sulfonyl analogues Han, Shuwen

119 C p.
artikel
60 Structure elucidation, biogenesis, and bioactivities of acylphloroglucinol-derived meroterpenoid enantiomers from Dryopteris crassirhizoma Hai, Ping

119 C p.
artikel
61 Synthesis and anti-inflammatory activities of glycyrrhetinic acid derivatives containing disulfide bond Zhang, Qiuping

119 C p.
artikel
62 Synthesis and biological evaluation of novel rhodanine-based structures with antiviral activity towards HHV-6 virus Gentili, Valentina

119 C p.
artikel
63 Synthesis and identification of a novel skeleton of N-(pyridin-3-yl) proline as a selective CDK4/6 inhibitor with anti-breast cancer activities Liang, Jing-wei

119 C p.
artikel
64 Synthesis and structure activity relationship of the first class of LXR inverse agonists Elgendy, Bahaa

119 C p.
artikel
65 Synthesis, anticancer evaluation and molecular docking of new benzothiazole scaffolds targeting FGFR-1 Abd El-Meguid, Eman A.

119 C p.
artikel
66 Synthesis of N-aryl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridin-7-amines and their photodynamic properties in the human skin melanoma cell line G361 Razmienė, Beatričė

119 C p.
artikel
67 Synthesis of new clioquinol derivatives as potent α-glucosidase inhibitors; molecular docking, kinetic and structure–activity relationship studies Wali, Shoukat

119 C p.
artikel
68 Synthesis of novel thiazolidinic-phthalimide derivatives evaluated as new multi-target antiepileptic agents de Oliveira, Maria Cecilia V.A.

119 C p.
artikel
69 Synthesis, structure, properties and antimicrobial activity of para trifluoromethyl phenylboronic derivatives Adamczyk-Woźniak, Agnieszka

119 C p.
artikel
70 Systemic pharmacological verification of Baixianfeng decoction regulating TNF-PI3K-Akt-NF-κB pathway in treating rheumatoid arthritis Wei, Xin

119 C p.
artikel
71 Tetrodecadazinone, a novel tetrodecamycin-pyridazinone hybrid with anti-liver fibrosis activity from Streptomyces sp. HU051 Liu, Ruo-Xi

119 C p.
artikel
72 The C-terminal segment of Leishmania major HslU: Toward potential inhibitors of LmHslVU activity Singh, Priyanka

119 C p.
artikel
73 The molecular mechanism, targets, and novel molecules in the treatment of Alzheimer’s disease Verma, Akash

119 C p.
artikel
74 The role of remote flavin adenine dinucleotide pieces in the oxidative decarboxylation catalyzed by salicylate hydroxylase Pereira, Mozart S.

119 C p.
artikel
75 Total extract of Anemarrhenae Rhizoma attenuates bleomycin-induced pulmonary fibrosis in rats Shen, Xue-Bin

119 C p.
artikel
76 Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors Bass, Amr K.A.

119 C p.
artikel
77 UV-guided isolation of enantiomeric polyacetylenes from Bupleurum scorzonerifolium Willd. with inhibitory effects against LPS-induced NO release in BV-2 microglial cells Hong, Wei

119 C p.
artikel
78 Virtual screening and in vitro validation of natural compound inhibitors against SARS-CoV-2 spike protein Power, Helen

119 C p.
artikel
                             78 gevonden resultaten
 
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