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                             117 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A facile approach synthesis of benzoylaryl benzimidazole as potential α-amylase and α-glucosidase inhibitor with antioxidant activity Aroua, Lotfi M.
114 C p.
 artikel
2 3-Alkenyl-2-oxindoles: Synthesis, antiproliferative and antiviral properties against SARS-CoV-2 Girgis, Adel S.
114 C p.
 artikel
3 A magnified aptamer fluorescence sensor based on the metal organic frameworks adsorbed DNA with enzyme catalysis amplification for ultra-sensitive determination of ATP and its logic gate operation Yao, Jun
114 C p.
 artikel
4 An optimized BRD4 inhibitor effectively eliminates NF-κB-driven triple-negative breast cancer cells Yang, Guan-Jun
114 C p.
 artikel
5 Anti-diabetic potential of Masclura tricuspidata leaves: Prenylated isoflavonoids with α-glucosidase inhibitory and anti-glycation activity Jo, Yang Hee
114 C p.
 artikel
6 Anti-melanogenesis and anti-tyrosinase properties of aryl-substituted acetamides of phenoxy methyl triazole conjugated with thiosemicarbazide: Design, synthesis and biological evaluations Hosseinpoor, Hona
114 C p.
 artikel
7 Anti-MRSA drug discovery by ligand-based virtual screening and biological evaluation Lian, Xu
114 C p.
 artikel
8 Anti-tumor compounds identification from gossypol Groebke imidazopyridine product Wang, Wei
114 C p.
 artikel
9 Apoptotic effect of chromanone derivative, hyrtiosone A from marine demosponge Hyrtios erectus in hepatocellular carcinoma HepG2 cells Chakraborty, Kajal
114 C p.
 artikel
10 Application of a marine luminescent Vibrio sp. B4L for biosynthesis of silver nanoparticles with unique characteristics, biochemical properties, antibacterial and antibiofilm activities Zamanpour, Noushin
114 C p.
 artikel
11 Artematrovirenins A–P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens Su, Li-Hua
114 C p.
 artikel
12 3-Arylamino-quinoxaline-2-carboxamides inhibit the PI3K/Akt/mTOR signaling pathways to activate P53 and induce apoptosis Chen, Nan-Ying
114 C p.
 artikel
13 Bioactive sesquiterpenes from Inula helenium Zheng, Xiaoqin
114 C p.
 artikel
14 Biological evaluation of mitochondria targeting small molecules as potent anticancer drugs Luo, Shuhua
114 C p.
 artikel
15 9-Bromo-2,3-diethylbenzo[de]chromene-7,8-dione (MSN54): A novel non-intercalative topoisomerase II catalytic inhibitor Mai, Yan-Wen
114 C p.
 artikel
16 Carbazole alkaloids with potential cytotoxic activities targeted on PCK2 protein from Murraya microphylla Ma, Xiao-Li
114 C p.
 artikel
17 Chemical constituents from basidiomycete Basidioradulum radula culture medium and their cytotoxic effect on human prostate cancer DU-145 cells Ryu, Seung Mok
114 C p.
 artikel
18 Computational discovery, structural optimization and biological evaluation of novel inhibitors targeting transient receptor potential vanilloid type 3 (TRPV3) Zhang, Fang
114 C p.
 artikel
19 Computational studies and sever apoptotic bioactivity of new heterocyclic cyanoacrylamide based p-fluorophenyl and p-phenolic compounds against liver carcinoma (Hepg2) Mohamed, Magda F.
114 C p.
 artikel
20 Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer’s disease Godyń, Justyna
114 C p.
 artikel
21 Design and synthesis of novel quinazolinone-pyrazole derivatives as potential α-glucosidase inhibitors: Structure-activity relationship, molecular modeling and kinetic study Azimi, Fateme
114 C p.
 artikel
22 Design and synthesis of novel 20(S)-α-aminophosphonate derivatives of camptothecin as potent antitumor agents Chen, Yu-Yuan
114 C p.
 artikel
23 Design, green synthesis, antioxidant activity screening, and evaluation of protective effect on cerebral ischemia reperfusion injury of novel monoenone monocarbonyl curcumin analogs He, Wenfei
114 C p.
 artikel
24 Design, synthesis and anticancer evaluation of new 4-anilinoquinoline-3-carbonitrile derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers Zou, Min
114 C p.
 artikel
25 Design, synthesis and bioactivity study of evodiamine derivatives as multifunctional agents for the treatment of hepatocellular carcinoma Fan, Xiaohong
114 C p.
 artikel
26 Design, synthesis and biological evaluation of glycolamide, glycinamide, and β-amino carbonyl 1,2,4-triazole derivatives as DPP-4 inhibitors Fuh, Mao-Tsu
114 C p.
 artikel
27 Design, synthesis, and biological evaluation of hydroxamic acid-substituted 2,4-diaryl aminopyrimidines as potent EGFRT790M/L858R inhibitors for the treatment of NSCLC Chen, Lixue
114 C p.
 artikel
28 Design, synthesis, and biological evaluation of 1-methyl-1H-pyrazolo[4,3-b]pyridine derivatives as novel small-molecule inhibitors targeting the PD-1/PD-L1 interaction Dai, Xinyan
114 C p.
 artikel
29 Design, synthesis and biological evaluation of novel diazaspirodecanone derivatives containing piperidine-4-carboxamide as chitin synthase inhibitors and antifungal agents Ji, Qinggang
114 C p.
 artikel
30 Design, synthesis and biological evaluation of novel pyrazolopyrimidone derivatives as potent PDE1 inhibitors Zhang, Bei
114 C p.
 artikel
31 Design, synthesis and biological evaluation of novel thiazole-derivatives as mitochondrial targeting inhibitors of cancer cells Dang, Xin
114 C p.
 artikel
32 Design, synthesis and biological evaluation of selective hybrid coumarin-thiazolidinedione aldose reductase-II inhibitors as potential antidiabetics Kumar Pasala, Vijay
114 C p.
 artikel
33 Design, synthesis and investigation of the mechanism of action underlying anti-leukemic effects of the quinolinequinones as LY83583 analogs Ciftci, Halil I.
114 C p.
 artikel
34 Design, synthesis and in vitro biological evaluation of a novel class of anti-adenovirus agents based on 3-amino-1,2-propanediol Mazzotta, Sarah
114 C p.
 artikel
35 Design, synthesis and pharmacological screening of novel renoprotective methionine-based peptidomimetics: Amelioration of cisplatin-induced nephrotoxicity Agha, Khalid A.
114 C p.
 artikel
36 Design, synthesis, in vitro and in silico studies of some novel thiazole-dihydrofuran derivatives as aromatase inhibitors Osmaniye, Derya
114 C p.
 artikel
37 Development of fluorinated and methoxylated benzothiazole derivatives as highly potent and selective cannabinoid CB2 receptor ligands Aly, Mayar W.
114 C p.
 artikel
38 Development of 2-Morpholino-N-hydroxybenzamides as anti-proliferative PC-PLC inhibitors Rees, Shaun W.P.
114 C p.
 artikel
39 Discovery of isoliquiritigenin analogues that reverse acute hepatitis by inhibiting macrophage polarization Yang, Junjie
114 C p.
 artikel
40 Discovery of new quinoxaline-2(1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation El-Adl, Khaled
114 C p.
 artikel
41 Discovery of Novel Dihydropyrimidine and hydroxamic acid hybrids as potent Helicobacter pylori Urease inhibitors Mamidala, Ravinder
114 C p.
 artikel
42 Discovery of 1,3,4,5-tetrasubstituted pyrazoles as anti-trypanosomatid agents: Identification of alterations in flagellar structure of L. amazonensis da Silva, Michael J.V.
114 C p.
 artikel
43 Discovery of the PARP (poly ADP-ribose polymerase) inhibitor 2-(1-(4,4-difluorocyclohexyl)piperidin-4-yl)-1H-benzo[d]imidazole-4-carboxamide for the treatment of cancer Tang, Lin
114 C p.
 artikel
44 Dissection of phospholipases A2 reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria Peña-Carrillo, Maria S.
114 C p.
 artikel
45 Editorial Board
114 C p.
 artikel
46 Enhancing the tumor cell selectivity of a rhodamine-decorated iridium(III) complex by conjugating with indomethacin for COX-2 targeted photodynamic therapy Liu, Chuangjun
114 C p.
 artikel
47 Euryfuranyl compounds from edible species of cuttlefish as potential anti-inflammatory leads attenuating NF-κB signaling cascade in lipopolysaccharide-activated macrophages Chakraborty, Kajal
114 C p.
 artikel
48 Facile green synthesis of zero-valent iron nanoparticles using barberry leaf extract (GnZVI@BLE) for photocatalytic reduction of hexavalent chromium Samadi, Zahra
114 C p.
 artikel
49 Facile synthesis, antimicrobial and antiviral evaluation of novel substituted phenyl 1,3-thiazolidin-4-one sulfonyl derivatives Mandal, Milan Kumar
114 C p.
 artikel
50 Furanaspermeroterpenes A and B, two unusual meroterpenoids with a unique 6/6/6/5/5 pentacyclic skeleton from the Marine-derived fungus Aspergillus terreus GZU-31-1 Tang, Yuqian
114 C p.
 artikel
51 Glioblastoma-specific anticancer activity of newly synthetized 3,5-disubstituted isoxazole and 1,4-disubstituted triazole-linked tyrosol conjugates Aissa, Imen
114 C p.
 artikel
52 High activity, high selectivity and high biocompatibility BODIPY-pyrimidine derivatives for fluorescence target recognition and evaluation of inhibitory activity Xu, Chi
114 C p.
 artikel
53 1H-1,2,3-triazole grafted tacrine-chalcone conjugates as potential cholinesterase inhibitors with the evaluation of their behavioral tests and oxidative stress in mice brain cells Rani, Anu
114 C p.
 artikel
54 Identification of inhibitors targeting polyketide synthase 13 of Mycobacterium tuberculosis as antituberculosis drug leads Wang, Xiao
114 C p.
 artikel
55 Identification of new building blocks by fragment screening for discovering GyrB inhibitors Yu, Ying
114 C p.
 artikel
56 Identification of new lead molecules against anticancer drug target TFIIH subunit P8 using biophysical and molecular docking studies Javaid, Sumaira
114 C p.
 artikel
57 Identification of novel Atg3-Atg8 inhibitors using virtual screening for autophagy modulation Leung, Euphemia
114 C p.
 artikel
58 Incorporation of a FRET pair within a phosphonate diester Harmon, Nyema M.
114 C p.
 artikel
59 In quest of small-molecules as potent non-competitive inhibitors against influenza Malbari, Khushboo
114 C p.
 artikel
60 Investigation of indole functionalized pyrazoles and oxadiazoles as anti-inflammatory agents: Synthesis, in-vivo, in-vitro and in-silico analysis Kumar, Devendra
114 C p.
 artikel
61 Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-β1 induced kidney proximal tubular cells Song, Ying-Ying
114 C p.
 artikel
62 Issue TOC
114 C p.
 artikel
63 Mechanism underlying Polygonum capitatum effect on Helicobacter pylori-associated gastritis based on network pharmacology Song, Xiaohan
114 C p.
 artikel
64 Microwave-assisted rapid synthesis of spirooxindole-pyrrolizidine analogues and their activity as anti-amyloidogenic agents de Silva, Nilamuni H.
114 C p.
 artikel
65 N-acylhydrazones confer inhibitory efficacy against New Delhi metallo-β-lactamase-1 Gao, Han
114 C p.
 artikel
66 New cytotoxic dichapetalins in the leaves of Phyllanthus acidus: Identification, quantitative analysis, and preliminary toxicity assessment Geng, Hui-Chun
114 C p.
 artikel
67 New dihydro-β-agarofuran sesquiterpenoids from Tripterygium wilfordii and their anti-inflammatory activity Cao, Bixuan
114 C p.
 artikel
68 New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies Othman, Ismail M.M.
114 C p.
 artikel
69 New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2 Seliem, Israa A.
114 C p.
 artikel
70 New secondary metabolites with immunosuppressive and BChE inhibitory activities from an endophytic fungus Daldinia sp. TJ403-LS1 Lin, Shuang
114 C p.
 artikel
71 Novel pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione (PBD) derivatives as selective HDAC6 inhibitors to suppress tumor metastasis and invasion in vitro and in vivo Li, Yanchun
114 C p.
 artikel
72 Novel thiazolidine derivatives as potent selective pro-apoptotic agents Hafez, Donia E.
114 C p.
 artikel
73 Novel thienopyrimidine-aminothiazole hybrids: Design, synthesis, antimicrobial screening, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and VEGFR-2 inhibition El-Dash, Yara
114 C p.
 artikel
74 Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and molecular modeling studies Abdellatif, Khaled R.A.
114 C p.
 artikel
75 Pharmacophore-based drug design of AChE and BChE dual inhibitors as potential anti-Alzheimer’s disease agents Gao, Hongwei
114 C p.
 artikel
76 Phenolic constituents isolated from Senna tora sprouts and their neuroprotective effects against glutamate-induced oxidative stress in HT22 and R28 cells Kwon, Jaeyoung
114 C p.
 artikel
77 Polycyclic polyprenylated acylphloroglucinol congeners from Garcinia yunnanensis Hu with inhibitory effect on α-hemolysin production in Staphylococcus aureus Zheng, Dan
114 C p.
 artikel
78 Polycyclic polyprenylated acylphloroglucinols with immunosuppressive activity from Hypericum perforatum and absolute configurations assignment of previously reported analogues Guo, Yi
114 C p.
 artikel
79 Pomegranate peel extract polyphenols attenuate the SARS-CoV-2 S-glycoprotein binding ability to ACE2 Receptor: In silico and in vitro studies Suručić, Relja
114 C p.
 artikel
80 Potential antibacterial ethanol-bridged purine azole hybrids as dual-targeting inhibitors of MRSA Hu, Yuanyuan
114 C p.
 artikel
81 Potential drug development and therapeutic approaches for clinical intervention in COVID-19 Dowarah, Jayanta
114 C p.
 artikel
82 Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway Li, Shen
114 C p.
 artikel
83 PROTACs technology for targeting non-oncoproteins: Advances and perspectives Wang, Chao
114 C p.
 artikel
84 p-Trifluoromethyl- and p-pentafluorothio-substituted curcuminoids of the 2,6-di[(E)-benzylidene)]cycloalkanone type: Syntheses and activities against Leishmania major and Toxoplasma gondii parasites Al Nasr, Ibrahim S.
114 C p.
 artikel
85 Pyrazoline derivatives as tubulin polymerization inhibitors with one hit for Vascular Endothelial Growth Factor Receptor 2 inhibition Yang, Bing
114 C p.
 artikel
86 Rational design-aided discovery of novel 1,2,4-oxadiazole derivatives as potential EGFR inhibitors Unadkat, Vishal
114 C p.
 artikel
87 Rational design of phenyl thiophene (pyridine) derivatives that overcome P-glycoprotein mediated MDR in MCF-7/ADR cell Li, Ya-Sheng
114 C p.
 artikel
88 Recent developments in mitogen activated protein kinase inhibitors as potential anticancer agents Singh, Vikram Jeet
114 C p.
 artikel
89 Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review Mermer, Arif
114 C p.
 artikel
90 Revisiting ageless antiques; synthesis, biological evaluation, docking simulation and mechanistic insights of 1,4-Dihydropyridines as anticancer agents Sidhom, Peter A.
114 C p.
 artikel
91 Self-assembly of bio-inspired heterochiral peptides Florio, Daniele
114 C p.
 artikel
92 Sonapatha (Oroxylum indicum) mediates cytotoxicity in cultured HeLa cells by inducing apoptosis and suppressing NF-κB, COX-2, RASSF7 and NRF2 Lalrinzuali, Khawlhring
114 C p.
 artikel
93 Structural exploration of multifunctional monoamine oxidase B inhibitors as potential drug candidates against Alzheimer’s disease Zhang, Changjun
114 C p.
 artikel
94 Structure-activity relationship study of dihydroartemisinin C-10 hemiacetal derivatives as Toll-like receptor 4 antagonists Wang, Shuo
114 C p.
 artikel
95 Synthesis and comparison of in vitro dual anti-infective activities of novel naphthoquinone hybrids and atovaquone Erasmus, Chané
114 C p.
 artikel
96 Synthesis and evaluation of the anti-inflammatory activity of novel 8-quinolinesulfonamide derivatives as TLR4/MD-2 inhibitors with efficacy in adjuvant-induced arthritis Liu, Tongtong
114 C p.
 artikel
97 Synthesis and pharmacological evaluation of pomalidomide derivatives useful for sickle cell disease treatment de Melo, Thais Regina Ferreira
114 C p.
 artikel
98 Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone Riaz, Muhammad Tariq
114 C p.
 artikel
99 Synthesis, biological evaluation, and molecular docking analysis of novel linker-less benzamide based potent and selective HDAC3 inhibitors Routholla, Ganesh
114 C p.
 artikel
100 Synthesis, DFT calculation, pharmacological evaluation, and catalytic application in the synthesis of diverse pyrano[2,3-c]pyrazole derivatives Amer, Mostafa M.K.
114 C p.
 artikel
101 Synthesis, in vitro biological investigation, and molecular dynamics simulations of thiazolopyrimidine based compounds as corticotrophin releasing factor receptor-1 antagonists Elgiushy, Hossam R.
114 C p.
 artikel
102 Synthesis of a novel glibenclamide-pioglitazone hybrid compound and its effects on glucose homeostasis in normal and insulin-resistant rats Pires Mendes, Camila
114 C p.
 artikel
103 Synthesis of 3-aryl-4-(N-aryl)aminocoumarins via photoredox arylation and the evaluation of their biological activity Carneiro, Leonardo S.A.
114 C p.
 artikel
104 Synthesis of benzoxazole-based vorinostat analogs and their antiproliferative activity Mantzourani, Christiana
114 C p.
 artikel
105 Synthesis of 1,4-dihydropyrazolo[4,3-b]indoles via intramolecular C(sp2)-N bond formation involving nitrene insertion, DFT study and their anticancer assessment Kaur, Manpreet
114 C p.
 artikel
106 Synthesis of new hydrazone derivatives and evaluation of their monoamine oxidase inhibitory activity Tok, Fatih
114 C p.
 artikel
107 Synthesis of novel 5-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-1,3,4-oxadiazole-2-thiol derivatives as potential glucosidase inhibitors Gani, Ramesh S.
114 C p.
 artikel
108 Synthesis, spectral characterization, DFT calculations, pharmacological studies, CT-DNA binding and molecular docking of potential N, O-multidentate chelating ligand and its VO(II), Zn(II) and ZrO(II) chelates Abdel-Rahman, Laila H.
114 C p.
 artikel
109 Tailor-made novel electrospun polystyrene/poly(d,l-lactide-co-glycolide) for oxidoreductases immobilization: Improvement of catalytic properties under extreme reaction conditions Jankowska, Katarzyna
114 C p.
 artikel
110 The chemical diversity, the attractant, anti-acetylcholinesterase, and antifungal activities of metabolites from biocontrol Trichoderma harzianum uncovered by OSMAC strategy Wang, Xue-Yin
114 C p.
 artikel
111 The Configuration-Dependent Anti-Leukemic Effect of Manoalide Stereoisomers: Reignite Research Interest in these Sponge-Derived Sesterterpenoids Lai, Kuei-Hung
114 C p.
 artikel
112 The design and synthesis of transient receptor potential vanilloid 3 inhibitors with novel skeleton Lv, Mengqi
114 C p.
 artikel
113 The design, synthesis and cellular imaging of a tumor-anchored, potent and cell-permeable BRD4-targeted fluorescent ligands Zhang, Hang
114 C p.
 artikel
114 The inhibition of catechol O-methyltransferase and monoamine oxidase by tetralone and indanone derivatives substituted with the nitrocatechol moiety de Beer, Andries D.
114 C p.
 artikel
115 Unusual polyoxygenated casbane diterpenoids from the South China Sea soft coral Sinularia erecta Liu, Jiao
114 C p.
 artikel
116 UV-fluorescence probe for detection Ni2+ with colorimetric/spectral dual-mode analysis method and its practical application Zhang, Yingying
114 C p.
 artikel
117 Virtual and experimental high throughput screening of substituted hydrazones on β-Tubulin polymerization Xavier, Janet Sabina
114 C p.
 artikel
                             117 gevonden resultaten
 
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