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Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and molecular modeling studies |
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Titel: |
Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and molecular modeling studies |
Auteur: |
Abdellatif, Khaled R.A. Abdelall, Eman K.A. Elshemy, Heba A.H. Philoppes, John N. Hassanein, Emad H.M. Kahk, Nesma M. |
Verschenen in: |
Bioorganic chemistry |
Paginering: |
Jaargang 114 () nr. C pagina's p. |
Jaar: |
2021 |
Inhoud: |
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Uitgever: |
Elsevier Inc. |
Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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