nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A novel multifunctional 2-nitroimidazole-based bioreductive linker and its application in hypoxia-activated prodrugs
|
Huang, Ying |
|
|
101 |
C |
p. |
artikel |
2 |
Anticancer potential of new 3-nitroaryl-6-(N-methyl)piperazin-1,2,4-triazolo[3,4-a]phthalazines targeting voltage-gated K+ channel: Copper-catalyzed one-pot synthesis from 4-chloro-1-phthalazinyl-arylhydrazones
|
Romero, Angel H. |
|
|
101 |
C |
p. |
artikel |
3 |
Antimicrobial and antiproliferative activity studies of some new quinoline-3-carbaldehyde hydrazone derivatives
|
Puskullu, Mustafa Orhan |
|
|
101 |
C |
p. |
artikel |
4 |
Antimicrobial evaluation and docking study of some new substituted benzimidazole-2yl derivatives
|
Abdel-Motaal, Marwa |
|
|
101 |
C |
p. |
artikel |
5 |
A Pt(IV)-based mononitro-naphthalimide conjugate with minimized side-effects targeting DNA damage response via a dual-DNA-damage approach to overcome cisplatin resistance
|
Li, Yingguang |
|
|
101 |
C |
p. |
artikel |
6 |
3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?
|
Mellado, Marco |
|
|
101 |
C |
p. |
artikel |
7 |
8-Benzylaminoxanthine scaffold variations for selective ligands acting on adenosine A2A receptors. Design, synthesis and biological evaluation
|
Załuski, Michał |
|
|
101 |
C |
p. |
artikel |
8 |
Bioactive triterpenoids from Lantana camara showing anti-inflammatory activities in vitro and in vivo
|
Wu, Peng |
|
|
101 |
C |
p. |
artikel |
9 |
Bioactivity and molecular docking studies of some nickel complexes: New analogues for the treatment of Alzheimer, glaucoma and epileptic diseases
|
Kısa, Dursun |
|
|
101 |
C |
p. |
artikel |
10 |
Bisthioureas of pimelic acid and 4-methylsalicylic acid derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP): Synthesis and molecular docking studies
|
Mumtaz, Amara |
|
|
101 |
C |
p. |
artikel |
11 |
Chemical constituents of Ligusticum chuanxiong and their anti-inflammation and hepatoprotective activities
|
Yuan, Xiang |
|
|
101 |
C |
p. |
artikel |
12 |
Cladocladosin A, an unusual macrolide with bicyclo 5/9 ring system, and two thiomacrolides from the marine mangrove-derived endophytic fungus, Cladosporium cladosporioides MA-299
|
Zhang, Fan-Zhong |
|
|
101 |
C |
p. |
artikel |
13 |
COVID19 inhibitors: A prospective therapeutics
|
Jawaid Akhtar, Md |
|
|
101 |
C |
p. |
artikel |
14 |
Densely functionalized cinnolines: Controlled microwave-assisted facile one-pot multi-component synthesis and in vitro anticancer activity via apoptosis induction
|
Nazmy, Maiiada Hassan |
|
|
101 |
C |
p. |
artikel |
15 |
Design and synthesis of β-carboline linked aryl sulfonyl piperazine derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability
|
Lakshmi Manasa, Kesari |
|
|
101 |
C |
p. |
artikel |
16 |
Design, synthesis and anticonvulsant activity of new imidazolidindione and imidazole derivatives
|
Marzouk, Adel A. |
|
|
101 |
C |
p. |
artikel |
17 |
Design, synthesis, and antitumor activity of novel compounds based on 1,2,4-triazolophthalazine scaffold: Apoptosis-inductive and PCAF-inhibitory effects
|
Turky, Abdallah |
|
|
101 |
C |
p. |
artikel |
18 |
Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities
|
Ding, Jiaoli |
|
|
101 |
C |
p. |
artikel |
19 |
Design, synthesis and biological evaluation of novel 2-alkylidene 19-norcalcitriol analogs
|
Fabisiak, Adrian |
|
|
101 |
C |
p. |
artikel |
20 |
Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors
|
Wei, Qiangqiang |
|
|
101 |
C |
p. |
artikel |
21 |
Design, synthesis, and biological evaluation of novel dual PPARα/δ agonists for the treatment of T2DM
|
Ren, Qiang |
|
|
101 |
C |
p. |
artikel |
22 |
Design, synthesis and biological evaluation of novel fluoro-substituted benzimidazole derivatives with anti-hypertension activities
|
Wu, Zhuo |
|
|
101 |
C |
p. |
artikel |
23 |
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
|
Chen, Yu |
|
|
101 |
C |
p. |
artikel |
24 |
Design, synthesis, and cytotoxic screening of novel azole derivatives on hepatocellular carcinoma (HepG2 Cells)
|
Abdelhameid, Mohammed K. |
|
|
101 |
C |
p. |
artikel |
25 |
Design, synthesis and evaluation of benzothiazole derivatives as multifunctional agents
|
Djuidje, Ernestine Nicaise |
|
|
101 |
C |
p. |
artikel |
26 |
Design, synthesis, and in vitro evaluation of novel triazole analogues featuring isoxazole moieties as antifungal agents
|
Xie, Fei |
|
|
101 |
C |
p. |
artikel |
27 |
Design, synthesis and neuropharmacological evaluation of new 2,4-disubstituted-1,5-benzodiazepines as CNS active agents
|
Verma, Ramesh |
|
|
101 |
C |
p. |
artikel |
28 |
Design, synthesis, bioevaluation of LFC- and PA-tethered anthraquinone analogues of mitoxantrone
|
Xie, Xin-Wen |
|
|
101 |
C |
p. |
artikel |
29 |
Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents
|
Morcoss, Martha M. |
|
|
101 |
C |
p. |
artikel |
30 |
Design, synthesis, molecular docking and antiproliferative activity of some novel benzothiazole derivatives targeting EGFR/HER2 and TS
|
Abdellatif, Khaled R.A. |
|
|
101 |
C |
p. |
artikel |
31 |
Design, synthesis of 1,3-dimethylpyrimidine-2,4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity
|
Ma, Zonghui |
|
|
101 |
C |
p. |
artikel |
32 |
Development of broad-spectrum enterovirus antivirals based on quinoline scaffold
|
Musharrafieh, Rami |
|
|
101 |
C |
p. |
artikel |
33 |
Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models
|
Kim, Darong |
|
|
101 |
C |
p. |
artikel |
34 |
Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity
|
Khodyuk, Rejane Gonçalves Diniz |
|
|
101 |
C |
p. |
artikel |
35 |
Dimeric phenalenones from Talaromyces sp. (IQ-313) inhibit hPTP1B1-400: Insights into mechanistic kinetics from in vitro and in silico studies
|
Jiménez-Arreola, Brenda S. |
|
|
101 |
C |
p. |
artikel |
36 |
Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson’s disease: Synthesis, in vitro and in vivo studies
|
Rodríguez-Enríquez, Fernanda |
|
|
101 |
C |
p. |
artikel |
37 |
Discovery of monoamine oxidase A inhibitory peptides from hairtail (Trichiurus japonicus) using in vitro simulated gastrointestinal digestion and in silico studies
|
Yang, Xiaoxue |
|
|
101 |
C |
p. |
artikel |
38 |
Discovery of novel dual c-Met/HDAC inhibitors as a promising strategy for cancer therapy
|
Hu, Hao |
|
|
101 |
C |
p. |
artikel |
39 |
Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening
|
Han, Jie |
|
|
101 |
C |
p. |
artikel |
40 |
Discovery of tetrandrine derivatives as tumor migration, invasion and angiogenesis inhibitors
|
Zhang, Rong-Hong |
|
|
101 |
C |
p. |
artikel |
41 |
Diterpenoids as potential anti-inflammatory agents from Ajuga pantantha
|
Liu, Wenpei |
|
|
101 |
C |
p. |
artikel |
42 |
Diversity-oriented generation and biological evaluation of new chemical scaffolds bearing a 2,2-dimethyl-2H-chromene unit: Discovery of novel potent ANO1 inhibitors
|
Seo, Yohan |
|
|
101 |
C |
p. |
artikel |
43 |
Editorial Board
|
|
|
|
101 |
C |
p. |
artikel |
44 |
(3E,5E)-3,5-Bis(pyridin-3-methylene)-tetrahydrothiopyran-4-one enhances the inhibitory effect of gemcitabine on pancreatic cancer cells
|
Wu, Panpan |
|
|
101 |
C |
p. |
artikel |
45 |
Efficient biocatalytic strategy for one-pot Biginelli reaction via enhanced specific effects of microwave in a circulating reactor
|
Xie, Zong-Bo |
|
|
101 |
C |
p. |
artikel |
46 |
Efficient biogenesis of ZnO nanoparticles using extracellular extract of Saccharomyces cerevisiae : Evaluation of photocatalytic, cytotoxic and other biological activities
|
Motazedi, Razieh |
|
|
101 |
C |
p. |
artikel |
47 |
Exploration of certain 1,3-oxazole- and 1,3-thiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents
|
Anh, Duong Tien |
|
|
101 |
C |
p. |
artikel |
48 |
Further polyoxygenated cembranoids from South China Sea soft coral Sarcophyton ehrenbergi
|
Li, Geng |
|
|
101 |
C |
p. |
artikel |
49 |
Helix stabilization by stapled N-capping box
|
Pham, Thanh K. |
|
|
101 |
C |
p. |
artikel |
50 |
Interaction of dicentrinone, an antitrypanosomal aporphine alkaloid isolated from Ocotea puberula (Lauraceae), in cell membrane models at the air-water interface
|
Barbosa, Henrique |
|
|
101 |
C |
p. |
artikel |
51 |
Introducing of potent cytotoxic novel 2-(aroylamino)cinnamamide derivatives against colon cancer mediated by dual apoptotic signal activation and oxidative stress
|
Omar, Abdelsattar M. |
|
|
101 |
C |
p. |
artikel |
52 |
In vitro inhibitory effects of Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves proanthocyanidins on pancreatic α-amylase and their interaction
|
Wang, Mengting |
|
|
101 |
C |
p. |
artikel |
53 |
Issue TOC
|
|
|
|
101 |
C |
p. |
artikel |
54 |
Molecular mechanism of action of new 1,4-naphthoquinones tethered to 1,2,3-1H-triazoles with cytotoxic and selective effect against oral squamous cell carcinoma
|
Cavalcanti Chipoline, Ingrid |
|
|
101 |
C |
p. |
artikel |
55 |
Natural therapeutic agents for neurodegenerative diseases from the shells of Xanthoceras sorbifolium
|
Chen, Gang |
|
|
101 |
C |
p. |
artikel |
56 |
Neuroprotective effect of novel celecoxib derivatives against spinal cord injury via attenuation of COX-2, oxidative stress, apoptosisand inflammation
|
An, Yan |
|
|
101 |
C |
p. |
artikel |
57 |
New anti-neuroinflammatory steroids against LPS induced NO production in BV2 microglia cells by microbial transformation of isorhodeasapogenin
|
Wang, Yihai |
|
|
101 |
C |
p. |
artikel |
58 |
New complex polycyclic compounds: Synthesis, antiproliferative activity and mechanism of action
|
Daidone, Giuseppe |
|
|
101 |
C |
p. |
artikel |
59 |
New nitroindazole-porphyrin conjugates: Synthesis, characterization and antibacterial properties
|
Eddahmi, Mohammed |
|
|
101 |
C |
p. |
artikel |
60 |
New prenylflavonol glycosides with xanthine oxidase inhibitory activity from the leaves of Cyclocarya paliurus
|
Ye, Zi-Jun |
|
|
101 |
C |
p. |
artikel |
61 |
Nitric oxide inhibitory iridoids as potential anti-inflammatory agents from Valeriana jatamansi
|
Wang, Huimei |
|
|
101 |
C |
p. |
artikel |
62 |
N-methoxy-β-carboline alkaloids with inhibitory activities against Aβ 42 aggregation and acetylcholinesterase from the stems of Picrasma quassioides
|
Zhang, Jie |
|
|
101 |
C |
p. |
artikel |
63 |
Norcolocynthenins A and B, two cucurbitane 3-nor-Triterpenoids from Citrullus colocynthis and their cytotoxicity
|
Liu, Yushuang |
|
|
101 |
C |
p. |
artikel |
64 |
Novel carbazole-stilbene hybrids as multifunctional anti-Alzheimer agents
|
Patel, Dushyant V. |
|
|
101 |
C |
p. |
artikel |
65 |
Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects
|
Omar, Abdelsattar M. |
|
|
101 |
C |
p. |
artikel |
66 |
Novel propanolamine derivatives attached to 2-metoxifenol moiety: Synthesis, characterization, biological properties, and molecular docking studies
|
Genc Bilgicli, Hayriye |
|
|
101 |
C |
p. |
artikel |
67 |
Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases
|
Cianni, Lorenzo |
|
|
101 |
C |
p. |
artikel |
68 |
Phytosterols disaggregate bovine serum albumin under the glycation conditions through interacting with its glycation sites and altering its secondary structure elements
|
Sobhy, Remah |
|
|
101 |
C |
p. |
artikel |
69 |
Prenylated chromones and flavonoids from Artocarpus heterophyllus with their potential antiproliferative and anti-inflammatory activities
|
Liu, Yan-Ping |
|
|
101 |
C |
p. |
artikel |
70 |
Recent progress of antibacterial natural products: Future antibiotics candidates
|
Dai, Jiangkun |
|
|
101 |
C |
p. |
artikel |
71 |
Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors
|
Hadi, Soha R. Abd El |
|
|
101 |
C |
p. |
artikel |
72 |
Serratane triterpenoids from Lycopodium complanatum and their anti-cancer and anti-inflammatory activities
|
Zhou, Wenhao |
|
|
101 |
C |
p. |
artikel |
73 |
Sesquiterpenoids isolated from the flower of Inula japonica as potential antitumor leads for intervention of paclitaxel-resistant non-small-cell lung cancer
|
Ding, Yahui |
|
|
101 |
C |
p. |
artikel |
74 |
Synthesis and anticancer activity of some pyrimidine derivatives with aryl urea moieties as apoptosis-inducing agents
|
Kilic-Kurt, Zühal |
|
|
101 |
C |
p. |
artikel |
75 |
Synthesis and anti-parasitic activity of achiral N-benzylated phosphoramidic acid derivatives
|
Adeyemi, Christiana M. |
|
|
101 |
C |
p. |
artikel |
76 |
Synthesis and antitumor activity of α,β-unsaturated carbonyl moiety- containing oleanolic acid derivatives targeting PI3K/AKT/mTOR signaling pathway
|
Wang, Shi-Sheng |
|
|
101 |
C |
p. |
artikel |
77 |
Synthesis and cholinesterase inhibiting potential of A-ring azepano- and 3-amino-3,4-seco-triterpenoids
|
Kazakova, Oxana |
|
|
101 |
C |
p. |
artikel |
78 |
Synthesis and computational studies of highly selective inhibitors of human recombinant tissue non-specific alkaline phosphatase (h-TNAP): A therapeutic target against vascular calcification
|
Andleeb, Hina |
|
|
101 |
C |
p. |
artikel |
79 |
Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase
|
Dawood, Dina H. |
|
|
101 |
C |
p. |
artikel |
80 |
Synthesis and screening of (E)-3-(2-benzylidenehydrazinyl)-5,6-diphenyl-1,2,4-triazine analogs as novel dual inhibitors of α-amylase and α-glucosidase
|
Shamim, Shahbaz |
|
|
101 |
C |
p. |
artikel |
81 |
Synthesis, anti-microbial and anti-inflammatory activities of 18β-glycyrrhetinic acid derivatives
|
Yang, Yang |
|
|
101 |
C |
p. |
artikel |
82 |
Synthesis, α-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives
|
Menteşe, Emre |
|
|
101 |
C |
p. |
artikel |
83 |
Synthesis of a novel fluorescent berberine derivative convenient for its subcellular localization study
|
Jin, Meng |
|
|
101 |
C |
p. |
artikel |
84 |
Synthesis of furocoumarin–stilbene hybrids as potential multifunctional drugs against multiple biochemical targets associated with Alzheimer’s disease
|
Agbo, Emmanuel N. |
|
|
101 |
C |
p. |
artikel |
85 |
Synthesis, pharmacological evaluation and mechanistic study of scutellarin methyl ester -4′-dipeptide conjugates for the treatment of hypoxic-ischemic encephalopathy (HIE) in rat pups
|
Li, Tao |
|
|
101 |
C |
p. |
artikel |
86 |
Synthetic approaches, anticancer potential, HSP90 inhibition, multitarget evaluation, molecular modeling and apoptosis mechanistic study of thioquinazolinone skeleton: Promising antibreast cancer agent
|
El-Shafey, Hamed W. |
|
|
101 |
C |
p. |
artikel |
87 |
Systematic research of H2dedpa derivatives as potent inhibitors of New Delhi Metallo-β-lactamase-1
|
Cui, De-Yun |
|
|
101 |
C |
p. |
artikel |
88 |
Targeted isolation of new polycyclic tetramate macrolactams from the deepsea-derived Streptomyces somaliensis SCSIO ZH66
|
Hou, Lukuan |
|
|
101 |
C |
p. |
artikel |
89 |
The fatty acid amide hydrolase and cyclooxygenase-inhibitory properties of novel amide derivatives of carprofen
|
Deplano, Alessandro |
|
|
101 |
C |
p. |
artikel |
90 |
Thiophene-based derivatives as anticancer agents: An overview on decade’s work
|
Archna, |
|
|
101 |
C |
p. |
artikel |
91 |
β-Turn mimetic synthetic peptides as amyloid-β aggregation inhibitors
|
Deike, Stefanie |
|
|
101 |
C |
p. |
artikel |