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                             91 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A novel multifunctional 2-nitroimidazole-based bioreductive linker and its application in hypoxia-activated prodrugs Huang, Ying

101 C p.
artikel
2 Anticancer potential of new 3-nitroaryl-6-(N-methyl)piperazin-1,2,4-triazolo[3,4-a]phthalazines targeting voltage-gated K+ channel: Copper-catalyzed one-pot synthesis from 4-chloro-1-phthalazinyl-arylhydrazones Romero, Angel H.

101 C p.
artikel
3 Antimicrobial and antiproliferative activity studies of some new quinoline-3-carbaldehyde hydrazone derivatives Puskullu, Mustafa Orhan

101 C p.
artikel
4 Antimicrobial evaluation and docking study of some new substituted benzimidazole-2yl derivatives Abdel-Motaal, Marwa

101 C p.
artikel
5 A Pt(IV)-based mononitro-naphthalimide conjugate with minimized side-effects targeting DNA damage response via a dual-DNA-damage approach to overcome cisplatin resistance Li, Yingguang

101 C p.
artikel
6 3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter? Mellado, Marco

101 C p.
artikel
7 8-Benzylaminoxanthine scaffold variations for selective ligands acting on adenosine A2A receptors. Design, synthesis and biological evaluation Załuski, Michał

101 C p.
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8 Bioactive triterpenoids from Lantana camara showing anti-inflammatory activities in vitro and in vivo Wu, Peng

101 C p.
artikel
9 Bioactivity and molecular docking studies of some nickel complexes: New analogues for the treatment of Alzheimer, glaucoma and epileptic diseases Kısa, Dursun

101 C p.
artikel
10 Bisthioureas of pimelic acid and 4-methylsalicylic acid derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP): Synthesis and molecular docking studies Mumtaz, Amara

101 C p.
artikel
11 Chemical constituents of Ligusticum chuanxiong and their anti-inflammation and hepatoprotective activities Yuan, Xiang

101 C p.
artikel
12 Cladocladosin A, an unusual macrolide with bicyclo 5/9 ring system, and two thiomacrolides from the marine mangrove-derived endophytic fungus, Cladosporium cladosporioides MA-299 Zhang, Fan-Zhong

101 C p.
artikel
13 COVID19 inhibitors: A prospective therapeutics Jawaid Akhtar, Md

101 C p.
artikel
14 Densely functionalized cinnolines: Controlled microwave-assisted facile one-pot multi-component synthesis and in vitro anticancer activity via apoptosis induction Nazmy, Maiiada Hassan

101 C p.
artikel
15 Design and synthesis of β-carboline linked aryl sulfonyl piperazine derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability Lakshmi Manasa, Kesari

101 C p.
artikel
16 Design, synthesis and anticonvulsant activity of new imidazolidindione and imidazole derivatives Marzouk, Adel A.

101 C p.
artikel
17 Design, synthesis, and antitumor activity of novel compounds based on 1,2,4-triazolophthalazine scaffold: Apoptosis-inductive and PCAF-inhibitory effects Turky, Abdallah

101 C p.
artikel
18 Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities Ding, Jiaoli

101 C p.
artikel
19 Design, synthesis and biological evaluation of novel 2-alkylidene 19-norcalcitriol analogs Fabisiak, Adrian

101 C p.
artikel
20 Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors Wei, Qiangqiang

101 C p.
artikel
21 Design, synthesis, and biological evaluation of novel dual PPARα/δ agonists for the treatment of T2DM Ren, Qiang

101 C p.
artikel
22 Design, synthesis and biological evaluation of novel fluoro-substituted benzimidazole derivatives with anti-hypertension activities Wu, Zhuo

101 C p.
artikel
23 Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain Chen, Yu

101 C p.
artikel
24 Design, synthesis, and cytotoxic screening of novel azole derivatives on hepatocellular carcinoma (HepG2 Cells) Abdelhameid, Mohammed K.

101 C p.
artikel
25 Design, synthesis and evaluation of benzothiazole derivatives as multifunctional agents Djuidje, Ernestine Nicaise

101 C p.
artikel
26 Design, synthesis, and in vitro evaluation of novel triazole analogues featuring isoxazole moieties as antifungal agents Xie, Fei

101 C p.
artikel
27 Design, synthesis and neuropharmacological evaluation of new 2,4-disubstituted-1,5-benzodiazepines as CNS active agents Verma, Ramesh

101 C p.
artikel
28 Design, synthesis, bioevaluation of LFC- and PA-tethered anthraquinone analogues of mitoxantrone Xie, Xin-Wen

101 C p.
artikel
29 Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents Morcoss, Martha M.

101 C p.
artikel
30 Design, synthesis, molecular docking and antiproliferative activity of some novel benzothiazole derivatives targeting EGFR/HER2 and TS Abdellatif, Khaled R.A.

101 C p.
artikel
31 Design, synthesis of 1,3-dimethylpyrimidine-2,4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity Ma, Zonghui

101 C p.
artikel
32 Development of broad-spectrum enterovirus antivirals based on quinoline scaffold Musharrafieh, Rami

101 C p.
artikel
33 Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models Kim, Darong

101 C p.
artikel
34 Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity Khodyuk, Rejane Gonçalves Diniz

101 C p.
artikel
35 Dimeric phenalenones from Talaromyces sp. (IQ-313) inhibit hPTP1B1-400: Insights into mechanistic kinetics from in vitro and in silico studies Jiménez-Arreola, Brenda S.

101 C p.
artikel
36 Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson’s disease: Synthesis, in vitro and in vivo studies Rodríguez-Enríquez, Fernanda

101 C p.
artikel
37 Discovery of monoamine oxidase A inhibitory peptides from hairtail (Trichiurus japonicus) using in vitro simulated gastrointestinal digestion and in silico studies Yang, Xiaoxue

101 C p.
artikel
38 Discovery of novel dual c-Met/HDAC inhibitors as a promising strategy for cancer therapy Hu, Hao

101 C p.
artikel
39 Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening Han, Jie

101 C p.
artikel
40 Discovery of tetrandrine derivatives as tumor migration, invasion and angiogenesis inhibitors Zhang, Rong-Hong

101 C p.
artikel
41 Diterpenoids as potential anti-inflammatory agents from Ajuga pantantha Liu, Wenpei

101 C p.
artikel
42 Diversity-oriented generation and biological evaluation of new chemical scaffolds bearing a 2,2-dimethyl-2H-chromene unit: Discovery of novel potent ANO1 inhibitors Seo, Yohan

101 C p.
artikel
43 Editorial Board
101 C p.
artikel
44 (3E,5E)-3,5-Bis(pyridin-3-methylene)-tetrahydrothiopyran-4-one enhances the inhibitory effect of gemcitabine on pancreatic cancer cells Wu, Panpan

101 C p.
artikel
45 Efficient biocatalytic strategy for one-pot Biginelli reaction via enhanced specific effects of microwave in a circulating reactor Xie, Zong-Bo

101 C p.
artikel
46 Efficient biogenesis of ZnO nanoparticles using extracellular extract of Saccharomyces cerevisiae : Evaluation of photocatalytic, cytotoxic and other biological activities Motazedi, Razieh

101 C p.
artikel
47 Exploration of certain 1,3-oxazole- and 1,3-thiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents Anh, Duong Tien

101 C p.
artikel
48 Further polyoxygenated cembranoids from South China Sea soft coral Sarcophyton ehrenbergi Li, Geng

101 C p.
artikel
49 Helix stabilization by stapled N-capping box Pham, Thanh K.

101 C p.
artikel
50 Interaction of dicentrinone, an antitrypanosomal aporphine alkaloid isolated from Ocotea puberula (Lauraceae), in cell membrane models at the air-water interface Barbosa, Henrique

101 C p.
artikel
51 Introducing of potent cytotoxic novel 2-(aroylamino)cinnamamide derivatives against colon cancer mediated by dual apoptotic signal activation and oxidative stress Omar, Abdelsattar M.

101 C p.
artikel
52 In vitro inhibitory effects of Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves proanthocyanidins on pancreatic α-amylase and their interaction Wang, Mengting

101 C p.
artikel
53 Issue TOC
101 C p.
artikel
54 Molecular mechanism of action of new 1,4-naphthoquinones tethered to 1,2,3-1H-triazoles with cytotoxic and selective effect against oral squamous cell carcinoma Cavalcanti Chipoline, Ingrid

101 C p.
artikel
55 Natural therapeutic agents for neurodegenerative diseases from the shells of Xanthoceras sorbifolium Chen, Gang

101 C p.
artikel
56 Neuroprotective effect of novel celecoxib derivatives against spinal cord injury via attenuation of COX-2, oxidative stress, apoptosisand inflammation An, Yan

101 C p.
artikel
57 New anti-neuroinflammatory steroids against LPS induced NO production in BV2 microglia cells by microbial transformation of isorhodeasapogenin Wang, Yihai

101 C p.
artikel
58 New complex polycyclic compounds: Synthesis, antiproliferative activity and mechanism of action Daidone, Giuseppe

101 C p.
artikel
59 New nitroindazole-porphyrin conjugates: Synthesis, characterization and antibacterial properties Eddahmi, Mohammed

101 C p.
artikel
60 New prenylflavonol glycosides with xanthine oxidase inhibitory activity from the leaves of Cyclocarya paliurus Ye, Zi-Jun

101 C p.
artikel
61 Nitric oxide inhibitory iridoids as potential anti-inflammatory agents from Valeriana jatamansi Wang, Huimei

101 C p.
artikel
62 N-methoxy-β-carboline alkaloids with inhibitory activities against Aβ 42 aggregation and acetylcholinesterase from the stems of Picrasma quassioides Zhang, Jie

101 C p.
artikel
63 Norcolocynthenins A and B, two cucurbitane 3-nor-Triterpenoids from Citrullus colocynthis and their cytotoxicity Liu, Yushuang

101 C p.
artikel
64 Novel carbazole-stilbene hybrids as multifunctional anti-Alzheimer agents Patel, Dushyant V.

101 C p.
artikel
65 Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects Omar, Abdelsattar M.

101 C p.
artikel
66 Novel propanolamine derivatives attached to 2-metoxifenol moiety: Synthesis, characterization, biological properties, and molecular docking studies Genc Bilgicli, Hayriye

101 C p.
artikel
67 Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases Cianni, Lorenzo

101 C p.
artikel
68 Phytosterols disaggregate bovine serum albumin under the glycation conditions through interacting with its glycation sites and altering its secondary structure elements Sobhy, Remah

101 C p.
artikel
69 Prenylated chromones and flavonoids from Artocarpus heterophyllus with their potential antiproliferative and anti-inflammatory activities Liu, Yan-Ping

101 C p.
artikel
70 Recent progress of antibacterial natural products: Future antibiotics candidates Dai, Jiangkun

101 C p.
artikel
71 Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors Hadi, Soha R. Abd El

101 C p.
artikel
72 Serratane triterpenoids from Lycopodium complanatum and their anti-cancer and anti-inflammatory activities Zhou, Wenhao

101 C p.
artikel
73 Sesquiterpenoids isolated from the flower of Inula japonica as potential antitumor leads for intervention of paclitaxel-resistant non-small-cell lung cancer Ding, Yahui

101 C p.
artikel
74 Synthesis and anticancer activity of some pyrimidine derivatives with aryl urea moieties as apoptosis-inducing agents Kilic-Kurt, Zühal

101 C p.
artikel
75 Synthesis and anti-parasitic activity of achiral N-benzylated phosphoramidic acid derivatives Adeyemi, Christiana M.

101 C p.
artikel
76 Synthesis and antitumor activity of α,β-unsaturated carbonyl moiety- containing oleanolic acid derivatives targeting PI3K/AKT/mTOR signaling pathway Wang, Shi-Sheng

101 C p.
artikel
77 Synthesis and cholinesterase inhibiting potential of A-ring azepano- and 3-amino-3,4-seco-triterpenoids Kazakova, Oxana

101 C p.
artikel
78 Synthesis and computational studies of highly selective inhibitors of human recombinant tissue non-specific alkaline phosphatase (h-TNAP): A therapeutic target against vascular calcification Andleeb, Hina

101 C p.
artikel
79 Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase Dawood, Dina H.

101 C p.
artikel
80 Synthesis and screening of (E)-3-(2-benzylidenehydrazinyl)-5,6-diphenyl-1,2,4-triazine analogs as novel dual inhibitors of α-amylase and α-glucosidase Shamim, Shahbaz

101 C p.
artikel
81 Synthesis, anti-microbial and anti-inflammatory activities of 18β-glycyrrhetinic acid derivatives Yang, Yang

101 C p.
artikel
82 Synthesis, α-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives Menteşe, Emre

101 C p.
artikel
83 Synthesis of a novel fluorescent berberine derivative convenient for its subcellular localization study Jin, Meng

101 C p.
artikel
84 Synthesis of furocoumarin–stilbene hybrids as potential multifunctional drugs against multiple biochemical targets associated with Alzheimer’s disease Agbo, Emmanuel N.

101 C p.
artikel
85 Synthesis, pharmacological evaluation and mechanistic study of scutellarin methyl ester -4′-dipeptide conjugates for the treatment of hypoxic-ischemic encephalopathy (HIE) in rat pups Li, Tao

101 C p.
artikel
86 Synthetic approaches, anticancer potential, HSP90 inhibition, multitarget evaluation, molecular modeling and apoptosis mechanistic study of thioquinazolinone skeleton: Promising antibreast cancer agent El-Shafey, Hamed W.

101 C p.
artikel
87 Systematic research of H2dedpa derivatives as potent inhibitors of New Delhi Metallo-β-lactamase-1 Cui, De-Yun

101 C p.
artikel
88 Targeted isolation of new polycyclic tetramate macrolactams from the deepsea-derived Streptomyces somaliensis SCSIO ZH66 Hou, Lukuan

101 C p.
artikel
89 The fatty acid amide hydrolase and cyclooxygenase-inhibitory properties of novel amide derivatives of carprofen Deplano, Alessandro

101 C p.
artikel
90 Thiophene-based derivatives as anticancer agents: An overview on decade’s work Archna,

101 C p.
artikel
91 β-Turn mimetic synthetic peptides as amyloid-β aggregation inhibitors Deike, Stefanie

101 C p.
artikel
                             91 gevonden resultaten
 
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