| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Application of protein knockdown strategy targeting β-sheet structure to multiple disease-associated polyglutamine proteins
|
Yamashita, Hiroko
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|
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28 |
1 |
p.
|
artikel
|
| 2 |
Artemisia: a promising plant for the treatment of cancer
|
Taleghani, Akram
|
|
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28 |
1 |
p.
|
artikel
|
| 3 |
Basil polysaccharides: A review on extraction, bioactivities and pharmacological applications
|
Zhan, Yanfei
|
|
|
28 |
1 |
p.
|
artikel
|
| 4 |
Bioothogonally applicable, π-extended rhodamines for super-resolution microscopy imaging for intracellular proteins
|
Egyed, Alexandra
|
|
|
28 |
1 |
p.
|
artikel
|
| 5 |
Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors
|
Malamas, Michael S.
|
|
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28 |
1 |
p.
|
artikel
|
| 6 |
Design of enkephalin modifications protected from brain extracellular peptidases providing long-term analgesia
|
Kropotova, Ekaterina S.
|
|
|
28 |
1 |
p.
|
artikel
|
| 7 |
Design, synthesis and biological evaluation of 8-(2-amino-1-hydroxyethyl)-6-hydroxy-1,4-benzoxazine-3(4H)-one derivatives as potent β2-adrenoceptor agonists
|
Yi, Ce
|
|
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28 |
1 |
p.
|
artikel
|
| 8 |
Design, synthesis and biological evaluation of imidazole and oxazole fragments as HIV-1 integrase-LEDGF/p75 disruptors and inhibitors of microbial pathogens
|
Rashamuse, Thompho J.
|
|
|
28 |
1 |
p.
|
artikel
|
| 9 |
Design, synthesis and biological evaluation of substituted flavones and aurones as potential anti-influenza agents
|
Chintakrindi, Anand S.
|
|
|
28 |
1 |
p.
|
artikel
|
| 10 |
Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity
|
Fuse, Shinichiro
|
|
|
28 |
1 |
p.
|
artikel
|
| 11 |
Development and characterization of a 68Ga-labeled A20FMDV2 peptide probe for the PET imaging of αvβ6 integrin-positive pancreatic ductal adenocarcinoma
|
Ui, Takashi
|
|
|
28 |
1 |
p.
|
artikel
|
| 12 |
Development of novel phenoxy-diketopiperazine-type plinabulin derivatives as potent antimicrotubule agents based on the co-crystal structure
|
Ding, Zhongpeng
|
|
|
28 |
1 |
p.
|
artikel
|
| 13 |
Discovery and preclinical development of AR453588 as an anti-diabetic glucokinase activator
|
Hinklin, Ronald J.
|
|
|
28 |
1 |
p.
|
artikel
|
| 14 |
Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide
|
Zhang, Fangqing
|
|
|
28 |
1 |
p.
|
artikel
|
| 15 |
Discovery of metyltetraprole: Identification of tetrazolinone pharmacophore to overcome QoI resistance
|
Matsuzaki, Yuichi
|
|
|
28 |
1 |
p.
|
artikel
|
| 16 |
Discovery of N-ethylpyridine-2-carboxamide derivatives as a novel scaffold for orally active γ-secretase modulators
|
Sekioka, Ryuichi
|
|
|
28 |
1 |
p.
|
artikel
|
| 17 |
Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification
|
Peng, Kewen
|
|
|
28 |
1 |
p.
|
artikel
|
| 18 |
Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies
|
Jiang, Fei
|
|
|
28 |
1 |
p.
|
artikel
|
| 19 |
Diversity & tractability revisited in collaborative small molecule phenotypic screening library design
|
Lahue, Brian R.
|
|
|
28 |
1 |
p.
|
artikel
|
| 20 |
Editorial Board
|
|
|
|
28 |
1 |
p.
|
artikel
|
| 21 |
Exploring structure-promiscuity relationships using dual-site promiscuity cliffs and corresponding single-site analogs
|
Hu, Huabin
|
|
|
28 |
1 |
p.
|
artikel
|
| 22 |
Generation of highly potent DYRK1A-dependent inducers of human β-Cell replication via Multi-Dimensional compound optimization
|
Allegretti, Paul A.
|
|
|
28 |
1 |
p.
|
artikel
|
| 23 |
Graphical Abstract Contents Continued
|
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28 |
1 |
p.
|
artikel
|
| 24 |
Graphical abstract TOC
|
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28 |
1 |
p.
|
artikel
|
| 25 |
Graphical abstract TOC
|
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28 |
1 |
p.
|
artikel
|
| 26 |
High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathways
|
Warchal, Scott J.
|
|
|
28 |
1 |
p.
|
artikel
|
| 27 |
Identification of antimalarial leads with dual falcipain-2 and falcipain-3 inhibitory activity
|
Rana, Devika
|
|
|
28 |
1 |
p.
|
artikel
|
| 28 |
Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening
|
Mamontova, E.M.
|
|
|
28 |
1 |
p.
|
artikel
|
| 29 |
Identification of small molecule inhibitors of human COQ7
|
Tsuganezawa, Keiko
|
|
|
28 |
1 |
p.
|
artikel
|
| 30 |
Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening
|
Ozgencil, Fikriye
|
|
|
28 |
1 |
p.
|
artikel
|
| 31 |
Investigating the effect of radiosensitizer for Ursolic Acid and Kamolonol Acetate on HCT-116 cell line
|
Hasan Abdali, Maede
|
|
|
28 |
1 |
p.
|
artikel
|
| 32 |
Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells
|
Kurisawa, Naoaki
|
|
|
28 |
1 |
p.
|
artikel
|
| 33 |
Lipidated α/Sulfono-α-AA heterogeneous peptides as antimicrobial agents for MRSA
|
Singh, Sylvia
|
|
|
28 |
1 |
p.
|
artikel
|
| 34 |
Mass spectrometry-based Cellular Thermal Shift Assay (CETSA®) for target deconvolution in phenotypic drug discovery
|
Friman, Tomas
|
|
|
28 |
1 |
p.
|
artikel
|
| 35 |
Modelling the binding mode of macrocycles: Docking and conformational sampling
|
Martin, Sarah J.
|
|
|
28 |
1 |
p.
|
artikel
|
| 36 |
Novel alkoxyamide-based histone deacetylase inhibitors reverse cisplatin resistance in chemoresistant cancer cells
|
Asfaha, Yodita
|
|
|
28 |
1 |
p.
|
artikel
|
| 37 |
Pan-specific and partially selective dye-labeled peptidic inhibitors of the polycomb paralog proteins
|
Milosevich, Natalia
|
|
|
28 |
1 |
p.
|
artikel
|
| 38 |
Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints
|
Winneroski, Leonard L.
|
|
|
28 |
1 |
p.
|
artikel
|
| 39 |
Pyrazolopyrimide library screening in glioma cells discovers highly potent antiproliferative leads that target the PI3K/mTOR pathway
|
Valero, Teresa
|
|
|
28 |
1 |
p.
|
artikel
|
| 40 |
Rational design, synthesis and biological profiling of new KDM4C inhibitors
|
Letfus, Vatroslav
|
|
|
28 |
1 |
p.
|
artikel
|
| 41 |
Selenium bioisosteric replacement of adenosine derivatives promoting adiponectin secretion increases the binding affinity to peroxisome proliferator-activated receptor δ
|
An, Seungchan
|
|
|
28 |
1 |
p.
|
artikel
|
| 42 |
Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase
|
Martinez-Gualda, Belén
|
|
|
28 |
1 |
p.
|
artikel
|
| 43 |
Superior inhibition of influenza virus hemagglutinin-mediated fusion by indole-substituted spirothiazolidinones
|
Cihan-Üstündağ, Gökçe
|
|
|
28 |
1 |
p.
|
artikel
|
| 44 |
Synthesis and antileishmanial activity of fluorinated rhodacyanine analogues: The ‘fluorine-walk’ analysis
|
Lasing, Thitiya
|
|
|
28 |
1 |
p.
|
artikel
|
| 45 |
Synthesis and biological activities of amino acids functionalized α-GalCer analogues
|
Ma, Weiwei
|
|
|
28 |
1 |
p.
|
artikel
|
| 46 |
Synthesis and characterization of 64Cu- and Cy5.5-labeled tetraiodothyroacetic acid derivatives for tumor angiogenesis imaging
|
Kim, Hyunjung
|
|
|
28 |
1 |
p.
|
artikel
|
| 47 |
Synthesis and evaluation of 2′-dihalo ribonucleotide prodrugs with activity against hepatitis C virus
|
Chris Krueger, A.
|
|
|
28 |
1 |
p.
|
artikel
|
| 48 |
Synthesis, in vitro and in vivo biological evaluation of novel graveolinine derivatives as potential anti-Alzheimer agents
|
Luo, Wen
|
|
|
28 |
1 |
p.
|
artikel
|
| 49 |
Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivatives
|
Babanezhad Harikandei, Kosar
|
|
|
28 |
1 |
p.
|
artikel
|
| 50 |
Synthesis of natural product-like polyprenylated phenols and quinones: Evaluation of their neuroprotective activities
|
Kamauchi, Hitoshi
|
|
|
28 |
1 |
p.
|
artikel
|
| 51 |
Tetrahydroquinoline units in flexible heteroarotinoids (Flex-Hets) convey anti-cancer properties in A2780 ovarian cancer cells
|
Gnanasekaran, Krishna Kumar
|
|
|
28 |
1 |
p.
|
artikel
|
| 52 |
The architecture of hydrogen and sulfur σ-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design
|
Kyriakis, Efthimios
|
|
|
28 |
1 |
p.
|
artikel
|
| 53 |
Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology
|
Sutherland, Hamish S.
|
|
|
28 |
1 |
p.
|
artikel
|
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