Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints
Titel:
Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints
Auteur:
Winneroski, Leonard L. Erickson, Jon A. Green, Steven J. Lopez, Jose E. Stout, Stephanie L. Porter, Warren J. Timm, David E. Audia, James E. Barberis, Mario Beck, James P. Boggs, Leonard N. Borders, Anthony R. Boyer, Robert D. Brier, Richard A. Hembre, Erik J. Hendle, Jörg Garcia-Losada, Pablo Minguez, Jose Miguel Mathes, Brian M. May, Patrick C. Monk, Scott A. Rankovic, Zoran Shi, Yuan Watson, Brian M. Yang, Zhixiang Mergott, Dustin J.