nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: Design of potent new ligands
|
Zha, Congxiang |
|
2014 |
22 |
1 |
p. 95-104 10 p. |
artikel |
2 |
Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues
|
Patrick, Donald A. |
|
2014 |
22 |
1 |
p. 559-576 18 p. |
artikel |
3 |
Bioorganic & Medicinal Chemistry Reviews and Perspectives
|
|
|
2014 |
22 |
1 |
p. I-IV nvt p. |
artikel |
4 |
Biphenyl derivatives incorporating urea unit as novel VEGFR-2 inhibitors: Design, synthesis and biological evaluation
|
Wang, Chen |
|
2014 |
22 |
1 |
p. 277-284 8 p. |
artikel |
5 |
Cloning, characterization and anion inhibition study of the δ-class carbonic anhydrase (TweCA) from the marine diatom Thalassiosira weissflogii
|
Del Prete, Sonia |
|
2014 |
22 |
1 |
p. 531-537 7 p. |
artikel |
6 |
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: Solution and X-ray crystallographic studies
|
Bozdag, Murat |
|
2014 |
22 |
1 |
p. 334-340 7 p. |
artikel |
7 |
Comparative molecular field analysis of fenoterol derivatives interacting with an agonist-stabilized form of the β2-adrenergic receptor
|
Plazinska, Anita |
|
2014 |
22 |
1 |
p. 234-246 13 p. |
artikel |
8 |
Corrigendum to “Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90)” [Bioorg. Med. Chem. 21 (2013) 7047–7063]
|
Brasca, Maria Gabriella |
|
2014 |
22 |
1 |
p. 662- 1 p. |
artikel |
9 |
Corrigendum to “3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-xL and Mcl-1” [Bioorg. Med. Chem. 21 (2013) 11–20]
|
Song, Ting |
|
2014 |
22 |
1 |
p. 663-664 2 p. |
artikel |
10 |
Curcumin glucuronides: Assessing the proliferative activity against human cell lines
|
Pal, Ashutosh |
|
2014 |
22 |
1 |
p. 435-439 5 p. |
artikel |
11 |
Dammarane triterpenes from the leaves of Panax ginseng enhance cellular immunity
|
Tran, Tien-Lam |
|
2014 |
22 |
1 |
p. 499-504 6 p. |
artikel |
12 |
Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma
|
Paige, Mikell |
|
2014 |
22 |
1 |
p. 478-487 10 p. |
artikel |
13 |
Design, synthesis and cytotoxic activity of novel sulfonylurea derivatives of podophyllotoxin
|
Zhang, Zhi-Jun |
|
2014 |
22 |
1 |
p. 204-210 7 p. |
artikel |
14 |
Design, synthesis, and enzyme kinetics of novel benzimidazole and quinoxaline derivatives as methionine synthase inhibitors
|
Elshihawy, Hosam |
|
2014 |
22 |
1 |
p. 550-558 9 p. |
artikel |
15 |
Design, synthesis and evaluation of novel indole derivatives as AKT inhibitors
|
Yang, Dezhi |
|
2014 |
22 |
1 |
p. 366-373 8 p. |
artikel |
16 |
Design, synthesis and molecular modeling of novel N-acylhydrazone derivatives as pyruvate dehydrogenase complex E1 inhibitors
|
He, Jun-Bo |
|
2014 |
22 |
1 |
p. 89-94 6 p. |
artikel |
17 |
Design, synthesis and preliminary SAR studies of novel N-arylmethyl substituted piperidine-linked aniline derivatives as potent HIV-1 NNRTIs
|
Zhang, Lingzi |
|
2014 |
22 |
1 |
p. 633-642 10 p. |
artikel |
18 |
Detection of apoptosis by PET/CT with the diethyl ester of [18F]ML-10 and fluorescence imaging with a dansyl analogue
|
Kadirvel, Manikandan |
|
2014 |
22 |
1 |
p. 341-349 9 p. |
artikel |
19 |
7,7′-Diazaindirubin—A small molecule inhibitor of casein kinase 2 in vitro and in cells
|
Cheng, Xinlai |
|
2014 |
22 |
1 |
p. 247-255 9 p. |
artikel |
20 |
Differential response of orthologous l,l-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds
|
McKinnie, Shaun M.K. |
|
2014 |
22 |
1 |
p. 523-530 8 p. |
artikel |
21 |
Discovery of novel antitumor dibenzocyclooctatetraene derivatives and related biphenyls as potent inhibitors of NF-κB signaling pathway
|
Yu, Fang-Lin |
|
2014 |
22 |
1 |
p. 325-333 9 p. |
artikel |
22 |
Discovery of the rapanone and suberonone mixture as a motif for leishmanicidal and antifungal applications
|
da Costa, Raphaella Correia |
|
2014 |
22 |
1 |
p. 135-140 6 p. |
artikel |
23 |
Editorial board
|
|
|
2014 |
22 |
1 |
p. IFC- 1 p. |
artikel |
24 |
Flexible and biomimetic analogs of triple uptake inhibitor 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: Synthesis, biological characterization, and development of a pharmacophore model
|
Sharma, Horrick |
|
2014 |
22 |
1 |
p. 311-324 14 p. |
artikel |
25 |
Fragment based discovery of arginine isosteres through REPLACE: Towards non-ATP competitive CDK inhibitors
|
Premnath, Padmavathy Nandha |
|
2014 |
22 |
1 |
p. 616-622 7 p. |
artikel |
26 |
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands
|
Gitto, Rosaria |
|
2014 |
22 |
1 |
p. 393-397 5 p. |
artikel |
27 |
Graphical contents list
|
|
|
2014 |
22 |
1 |
p. 1-17 17 p. |
artikel |
28 |
Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings
|
Lee, Hyun |
|
2014 |
22 |
1 |
p. 167-177 11 p. |
artikel |
29 |
Imatinib analogs as potential agents for PET imaging of Bcr-Abl and c-KIT expression at a kinase level
|
Peng, Zhenghong |
|
2014 |
22 |
1 |
p. 623-632 10 p. |
artikel |
30 |
Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties
|
Alafeefy, Ahmed M. |
|
2014 |
22 |
1 |
p. 141-147 7 p. |
artikel |
31 |
Intracellular accumulation of structurally varied isothiocyanates correlates with inhibition of nitric oxide production in proinflammatory stimuli-activated tumorigenic macrophage-like cells
|
Yamaguchi, Hideaki |
|
2014 |
22 |
1 |
p. 440-446 7 p. |
artikel |
32 |
Introduction of antioxidant-loaded liposomes into endothelial cell surfaces through DNA hybridization
|
Deno, Sho |
|
2014 |
22 |
1 |
p. 350-357 8 p. |
artikel |
33 |
Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone) aromatase inhibitors
|
Amato, Erica |
|
2014 |
22 |
1 |
p. 126-134 9 p. |
artikel |
34 |
Involvement of apoptosis and autophagy in the death of RPMI 8226 multiple myeloma cells by two enantiomeric sigma receptor ligands
|
Korpis, Katharina |
|
2014 |
22 |
1 |
p. 221-233 13 p. |
artikel |
35 |
Isolation of antiplasmodial anthraquinones from Kniphofia ensifolia, and synthesis and structure–activity relationships of related compounds
|
Dai, Yumin |
|
2014 |
22 |
1 |
p. 269-276 8 p. |
artikel |
36 |
Lipoic acid analogs with enhanced pharmacological activity
|
Kates, Steven A. |
|
2014 |
22 |
1 |
p. 505-512 8 p. |
artikel |
37 |
Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention
|
Desphande, Anil |
|
2014 |
22 |
1 |
p. 178-185 8 p. |
artikel |
38 |
Modeling in vitro inhibition of butyrylcholinesterase using molecular docking, multi-linear regression and artificial neural network approaches
|
Zheng, Fang |
|
2014 |
22 |
1 |
p. 538-549 12 p. |
artikel |
39 |
Natural product based leads to fight against leishmaniasis
|
Singh, Nisha |
|
2014 |
22 |
1 |
p. 18-45 28 p. |
artikel |
40 |
New carbocyclic nucleoside analogues with a bicyclo[2.2.1]heptane fragment as sugar moiety; Synthesis, X-ray crystallography and anticancer activity
|
Tănase, Constantin I. |
|
2014 |
22 |
1 |
p. 513-522 10 p. |
artikel |
41 |
New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid
|
Májer, Ferenc |
|
2014 |
22 |
1 |
p. 256-268 13 p. |
artikel |
42 |
New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase
|
Ferrer-Casal, Mariana |
|
2014 |
22 |
1 |
p. 398-405 8 p. |
artikel |
43 |
Optimization of potency and pharmacokinetics of tricyclic indole derived inhibitors of HCV NS5B polymerase. Identification of ester prodrugs with improved oral pharmacokinetics
|
Venkatraman, Srikanth |
|
2014 |
22 |
1 |
p. 447-458 12 p. |
artikel |
44 |
Probing the human estrogen receptor-α binding requirements for phenolic mono- and di-hydroxyl compounds: A combined synthesis, binding and docking study
|
McCullough, Christopher |
|
2014 |
22 |
1 |
p. 303-310 8 p. |
artikel |
45 |
Purinergic receptor P2X7: A novel target for anti-inflammatory therapy
|
Mehta, Nisha |
|
2014 |
22 |
1 |
p. 54-88 35 p. |
artikel |
46 |
Pyrrolizines: Promising scaffolds for anticancer drugs
|
Belal, Amany |
|
2014 |
22 |
1 |
p. 46-53 8 p. |
artikel |
47 |
Rational design and synthesis of topoisomerase I and II inhibitors based on oleanolic acid moiety for new anti-cancer drugs
|
Ashour, Ahmed |
|
2014 |
22 |
1 |
p. 211-220 10 p. |
artikel |
48 |
Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents
|
Low, Woon-Kai |
|
2014 |
22 |
1 |
p. 116-125 10 p. |
artikel |
49 |
Small molecule inhibitors of anthrax lethal factor toxin
|
Williams, John D. |
|
2014 |
22 |
1 |
p. 419-434 16 p. |
artikel |
50 |
Strategies for lead discovery: Application of footprint similarity targeting HIVgp41
|
Holden, Patrick M. |
|
2014 |
22 |
1 |
p. 651-661 11 p. |
artikel |
51 |
Synthesis and anticancer activities of thieno[3,2-d]pyrimidines as novel HDAC inhibitors
|
Tan, Qiu |
|
2014 |
22 |
1 |
p. 358-365 8 p. |
artikel |
52 |
Synthesis and anticancer evaluation of 3-substituted quinolin-4-ones and 2,3-dihydroquinolin-4-ones
|
Rajput, Santosh |
|
2014 |
22 |
1 |
p. 105-115 11 p. |
artikel |
53 |
Synthesis and biological evaluation of farnesylthiosalicylamides as potential anti-tumor agents
|
Ling, Yong |
|
2014 |
22 |
1 |
p. 374-380 7 p. |
artikel |
54 |
Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A1 adenosine receptor
|
Romagnoli, Romeo |
|
2014 |
22 |
1 |
p. 148-166 19 p. |
artikel |
55 |
Synthesis and evaluation of (−)- and (+)-[11C]galanthamine as PET tracers for cerebral acetylcholinesterase imaging
|
Kimura, Hiroyuki |
|
2014 |
22 |
1 |
p. 285-291 7 p. |
artikel |
56 |
Synthesis and evaluation of spiroisoxazoline oxindoles as anticancer agents
|
Ribeiro, Carlos J.A. |
|
2014 |
22 |
1 |
p. 577-584 8 p. |
artikel |
57 |
Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol
|
Åstrand, O. Alexander H. |
|
2014 |
22 |
1 |
p. 643-650 8 p. |
artikel |
58 |
Synthesis and insecticidal evaluation of novel anthranilic diamides containing N-substitued nitrophenylpyrazole
|
Zhang, Xiulan |
|
2014 |
22 |
1 |
p. 186-193 8 p. |
artikel |
59 |
Synthesis and pharmacological characterization of 1-benzyl-4-aminoindole-based thyroid hormone receptor β agonists
|
Takahashi, Naoki |
|
2014 |
22 |
1 |
p. 488-498 11 p. |
artikel |
60 |
Synthesis and SAR study of a novel series of dopamine receptor agonists
|
Risgaard, Rune |
|
2014 |
22 |
1 |
p. 381-392 12 p. |
artikel |
61 |
Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors
|
Liu, Wei |
|
2014 |
22 |
1 |
p. 292-302 11 p. |
artikel |
62 |
Synthesis, molecular modeling and biological evaluation of N-benzylidene-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetohydrazide derivatives as potential anticancer agents
|
Zhang, Fei |
|
2014 |
22 |
1 |
p. 468-477 10 p. |
artikel |
63 |
Synthesis of 3-(3-aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazines that have antibacterial activity and also inhibit inorganic pyrophosphatase
|
Lv, Wei |
|
2014 |
22 |
1 |
p. 406-418 13 p. |
artikel |
64 |
Synthesis of novel 2-cyano substituted glycyrrhetinic acid derivatives as inhibitors of cancer cells growth and NO production in LPS-activated J-774 cells
|
Salomatina, Oksana V. |
|
2014 |
22 |
1 |
p. 585-593 9 p. |
artikel |
65 |
The phytoalexins brassilexin and camalexin inhibit cyclobrassinin hydrolase, a unique enzyme from the fungal pathogen Alternaria brassicicola
|
Pedras, M. Soledade C. |
|
2014 |
22 |
1 |
p. 459-467 9 p. |
artikel |
66 |
The synthesis of novel taxoids for oral administration
|
Jing, Yun-rong |
|
2014 |
22 |
1 |
p. 194-203 10 p. |
artikel |
67 |
Towards cytotoxic and selective derivatives of maslinic acid
|
Siewert, Bianka |
|
2014 |
22 |
1 |
p. 594-615 22 p. |
artikel |