| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: Design of potent new ligands
|
Zha, Congxiang
|
|
2014
|
22 |
1 |
p. 95-104
10 p.
|
artikel
|
| 2 |
Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues
|
Patrick, Donald A.
|
|
2014
|
22 |
1 |
p. 559-576
18 p.
|
artikel
|
| 3 |
Bioorganic & Medicinal Chemistry Reviews and Perspectives
|
|
|
2014
|
22 |
1 |
p. I-IV
nvt p.
|
artikel
|
| 4 |
Biphenyl derivatives incorporating urea unit as novel VEGFR-2 inhibitors: Design, synthesis and biological evaluation
|
Wang, Chen
|
|
2014
|
22 |
1 |
p. 277-284
8 p.
|
artikel
|
| 5 |
Cloning, characterization and anion inhibition study of the δ-class carbonic anhydrase (TweCA) from the marine diatom Thalassiosira weissflogii
|
Del Prete, Sonia
|
|
2014
|
22 |
1 |
p. 531-537
7 p.
|
artikel
|
| 6 |
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: Solution and X-ray crystallographic studies
|
Bozdag, Murat
|
|
2014
|
22 |
1 |
p. 334-340
7 p.
|
artikel
|
| 7 |
Comparative molecular field analysis of fenoterol derivatives interacting with an agonist-stabilized form of the β2-adrenergic receptor
|
Plazinska, Anita
|
|
2014
|
22 |
1 |
p. 234-246
13 p.
|
artikel
|
| 8 |
Corrigendum to “Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90)” [Bioorg. Med. Chem. 21 (2013) 7047–7063]
|
Brasca, Maria Gabriella
|
|
2014
|
22 |
1 |
p. 662-
1 p.
|
artikel
|
| 9 |
Corrigendum to “3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-xL and Mcl-1” [Bioorg. Med. Chem. 21 (2013) 11–20]
|
Song, Ting
|
|
2014
|
22 |
1 |
p. 663-664
2 p.
|
artikel
|
| 10 |
Curcumin glucuronides: Assessing the proliferative activity against human cell lines
|
Pal, Ashutosh
|
|
2014
|
22 |
1 |
p. 435-439
5 p.
|
artikel
|
| 11 |
Dammarane triterpenes from the leaves of Panax ginseng enhance cellular immunity
|
Tran, Tien-Lam
|
|
2014
|
22 |
1 |
p. 499-504
6 p.
|
artikel
|
| 12 |
Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma
|
Paige, Mikell
|
|
2014
|
22 |
1 |
p. 478-487
10 p.
|
artikel
|
| 13 |
Design, synthesis and cytotoxic activity of novel sulfonylurea derivatives of podophyllotoxin
|
Zhang, Zhi-Jun
|
|
2014
|
22 |
1 |
p. 204-210
7 p.
|
artikel
|
| 14 |
Design, synthesis, and enzyme kinetics of novel benzimidazole and quinoxaline derivatives as methionine synthase inhibitors
|
Elshihawy, Hosam
|
|
2014
|
22 |
1 |
p. 550-558
9 p.
|
artikel
|
| 15 |
Design, synthesis and evaluation of novel indole derivatives as AKT inhibitors
|
Yang, Dezhi
|
|
2014
|
22 |
1 |
p. 366-373
8 p.
|
artikel
|
| 16 |
Design, synthesis and molecular modeling of novel N-acylhydrazone derivatives as pyruvate dehydrogenase complex E1 inhibitors
|
He, Jun-Bo
|
|
2014
|
22 |
1 |
p. 89-94
6 p.
|
artikel
|
| 17 |
Design, synthesis and preliminary SAR studies of novel N-arylmethyl substituted piperidine-linked aniline derivatives as potent HIV-1 NNRTIs
|
Zhang, Lingzi
|
|
2014
|
22 |
1 |
p. 633-642
10 p.
|
artikel
|
| 18 |
Detection of apoptosis by PET/CT with the diethyl ester of [18F]ML-10 and fluorescence imaging with a dansyl analogue
|
Kadirvel, Manikandan
|
|
2014
|
22 |
1 |
p. 341-349
9 p.
|
artikel
|
| 19 |
7,7′-Diazaindirubin—A small molecule inhibitor of casein kinase 2 in vitro and in cells
|
Cheng, Xinlai
|
|
2014
|
22 |
1 |
p. 247-255
9 p.
|
artikel
|
| 20 |
Differential response of orthologous l,l-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds
|
McKinnie, Shaun M.K.
|
|
2014
|
22 |
1 |
p. 523-530
8 p.
|
artikel
|
| 21 |
Discovery of novel antitumor dibenzocyclooctatetraene derivatives and related biphenyls as potent inhibitors of NF-κB signaling pathway
|
Yu, Fang-Lin
|
|
2014
|
22 |
1 |
p. 325-333
9 p.
|
artikel
|
| 22 |
Discovery of the rapanone and suberonone mixture as a motif for leishmanicidal and antifungal applications
|
da Costa, Raphaella Correia
|
|
2014
|
22 |
1 |
p. 135-140
6 p.
|
artikel
|
| 23 |
Editorial board
|
|
|
2014
|
22 |
1 |
p. IFC-
1 p.
|
artikel
|
| 24 |
Flexible and biomimetic analogs of triple uptake inhibitor 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: Synthesis, biological characterization, and development of a pharmacophore model
|
Sharma, Horrick
|
|
2014
|
22 |
1 |
p. 311-324
14 p.
|
artikel
|
| 25 |
Fragment based discovery of arginine isosteres through REPLACE: Towards non-ATP competitive CDK inhibitors
|
Premnath, Padmavathy Nandha
|
|
2014
|
22 |
1 |
p. 616-622
7 p.
|
artikel
|
| 26 |
From NMDA receptor antagonists to discovery of selective σ2 receptor ligands
|
Gitto, Rosaria
|
|
2014
|
22 |
1 |
p. 393-397
5 p.
|
artikel
|
| 27 |
Graphical contents list
|
|
|
2014
|
22 |
1 |
p. 1-17
17 p.
|
artikel
|
| 28 |
Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings
|
Lee, Hyun
|
|
2014
|
22 |
1 |
p. 167-177
11 p.
|
artikel
|
| 29 |
Imatinib analogs as potential agents for PET imaging of Bcr-Abl and c-KIT expression at a kinase level
|
Peng, Zhenghong
|
|
2014
|
22 |
1 |
p. 623-632
10 p.
|
artikel
|
| 30 |
Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties
|
Alafeefy, Ahmed M.
|
|
2014
|
22 |
1 |
p. 141-147
7 p.
|
artikel
|
| 31 |
Intracellular accumulation of structurally varied isothiocyanates correlates with inhibition of nitric oxide production in proinflammatory stimuli-activated tumorigenic macrophage-like cells
|
Yamaguchi, Hideaki
|
|
2014
|
22 |
1 |
p. 440-446
7 p.
|
artikel
|
| 32 |
Introduction of antioxidant-loaded liposomes into endothelial cell surfaces through DNA hybridization
|
Deno, Sho
|
|
2014
|
22 |
1 |
p. 350-357
8 p.
|
artikel
|
| 33 |
Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone) aromatase inhibitors
|
Amato, Erica
|
|
2014
|
22 |
1 |
p. 126-134
9 p.
|
artikel
|
| 34 |
Involvement of apoptosis and autophagy in the death of RPMI 8226 multiple myeloma cells by two enantiomeric sigma receptor ligands
|
Korpis, Katharina
|
|
2014
|
22 |
1 |
p. 221-233
13 p.
|
artikel
|
| 35 |
Isolation of antiplasmodial anthraquinones from Kniphofia ensifolia, and synthesis and structure–activity relationships of related compounds
|
Dai, Yumin
|
|
2014
|
22 |
1 |
p. 269-276
8 p.
|
artikel
|
| 36 |
Lipoic acid analogs with enhanced pharmacological activity
|
Kates, Steven A.
|
|
2014
|
22 |
1 |
p. 505-512
8 p.
|
artikel
|
| 37 |
Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention
|
Desphande, Anil
|
|
2014
|
22 |
1 |
p. 178-185
8 p.
|
artikel
|
| 38 |
Modeling in vitro inhibition of butyrylcholinesterase using molecular docking, multi-linear regression and artificial neural network approaches
|
Zheng, Fang
|
|
2014
|
22 |
1 |
p. 538-549
12 p.
|
artikel
|
| 39 |
Natural product based leads to fight against leishmaniasis
|
Singh, Nisha
|
|
2014
|
22 |
1 |
p. 18-45
28 p.
|
artikel
|
| 40 |
New carbocyclic nucleoside analogues with a bicyclo[2.2.1]heptane fragment as sugar moiety; Synthesis, X-ray crystallography and anticancer activity
|
Tănase, Constantin I.
|
|
2014
|
22 |
1 |
p. 513-522
10 p.
|
artikel
|
| 41 |
New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid
|
Májer, Ferenc
|
|
2014
|
22 |
1 |
p. 256-268
13 p.
|
artikel
|
| 42 |
New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase
|
Ferrer-Casal, Mariana
|
|
2014
|
22 |
1 |
p. 398-405
8 p.
|
artikel
|
| 43 |
Optimization of potency and pharmacokinetics of tricyclic indole derived inhibitors of HCV NS5B polymerase. Identification of ester prodrugs with improved oral pharmacokinetics
|
Venkatraman, Srikanth
|
|
2014
|
22 |
1 |
p. 447-458
12 p.
|
artikel
|
| 44 |
Probing the human estrogen receptor-α binding requirements for phenolic mono- and di-hydroxyl compounds: A combined synthesis, binding and docking study
|
McCullough, Christopher
|
|
2014
|
22 |
1 |
p. 303-310
8 p.
|
artikel
|
| 45 |
Purinergic receptor P2X7: A novel target for anti-inflammatory therapy
|
Mehta, Nisha
|
|
2014
|
22 |
1 |
p. 54-88
35 p.
|
artikel
|
| 46 |
Pyrrolizines: Promising scaffolds for anticancer drugs
|
Belal, Amany
|
|
2014
|
22 |
1 |
p. 46-53
8 p.
|
artikel
|
| 47 |
Rational design and synthesis of topoisomerase I and II inhibitors based on oleanolic acid moiety for new anti-cancer drugs
|
Ashour, Ahmed
|
|
2014
|
22 |
1 |
p. 211-220
10 p.
|
artikel
|
| 48 |
Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents
|
Low, Woon-Kai
|
|
2014
|
22 |
1 |
p. 116-125
10 p.
|
artikel
|
| 49 |
Small molecule inhibitors of anthrax lethal factor toxin
|
Williams, John D.
|
|
2014
|
22 |
1 |
p. 419-434
16 p.
|
artikel
|
| 50 |
Strategies for lead discovery: Application of footprint similarity targeting HIVgp41
|
Holden, Patrick M.
|
|
2014
|
22 |
1 |
p. 651-661
11 p.
|
artikel
|
| 51 |
Synthesis and anticancer activities of thieno[3,2-d]pyrimidines as novel HDAC inhibitors
|
Tan, Qiu
|
|
2014
|
22 |
1 |
p. 358-365
8 p.
|
artikel
|
| 52 |
Synthesis and anticancer evaluation of 3-substituted quinolin-4-ones and 2,3-dihydroquinolin-4-ones
|
Rajput, Santosh
|
|
2014
|
22 |
1 |
p. 105-115
11 p.
|
artikel
|
| 53 |
Synthesis and biological evaluation of farnesylthiosalicylamides as potential anti-tumor agents
|
Ling, Yong
|
|
2014
|
22 |
1 |
p. 374-380
7 p.
|
artikel
|
| 54 |
Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A1 adenosine receptor
|
Romagnoli, Romeo
|
|
2014
|
22 |
1 |
p. 148-166
19 p.
|
artikel
|
| 55 |
Synthesis and evaluation of (−)- and (+)-[11C]galanthamine as PET tracers for cerebral acetylcholinesterase imaging
|
Kimura, Hiroyuki
|
|
2014
|
22 |
1 |
p. 285-291
7 p.
|
artikel
|
| 56 |
Synthesis and evaluation of spiroisoxazoline oxindoles as anticancer agents
|
Ribeiro, Carlos J.A.
|
|
2014
|
22 |
1 |
p. 577-584
8 p.
|
artikel
|
| 57 |
Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol
|
Åstrand, O. Alexander H.
|
|
2014
|
22 |
1 |
p. 643-650
8 p.
|
artikel
|
| 58 |
Synthesis and insecticidal evaluation of novel anthranilic diamides containing N-substitued nitrophenylpyrazole
|
Zhang, Xiulan
|
|
2014
|
22 |
1 |
p. 186-193
8 p.
|
artikel
|
| 59 |
Synthesis and pharmacological characterization of 1-benzyl-4-aminoindole-based thyroid hormone receptor β agonists
|
Takahashi, Naoki
|
|
2014
|
22 |
1 |
p. 488-498
11 p.
|
artikel
|
| 60 |
Synthesis and SAR study of a novel series of dopamine receptor agonists
|
Risgaard, Rune
|
|
2014
|
22 |
1 |
p. 381-392
12 p.
|
artikel
|
| 61 |
Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors
|
Liu, Wei
|
|
2014
|
22 |
1 |
p. 292-302
11 p.
|
artikel
|
| 62 |
Synthesis, molecular modeling and biological evaluation of N-benzylidene-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetohydrazide derivatives as potential anticancer agents
|
Zhang, Fei
|
|
2014
|
22 |
1 |
p. 468-477
10 p.
|
artikel
|
| 63 |
Synthesis of 3-(3-aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazines that have antibacterial activity and also inhibit inorganic pyrophosphatase
|
Lv, Wei
|
|
2014
|
22 |
1 |
p. 406-418
13 p.
|
artikel
|
| 64 |
Synthesis of novel 2-cyano substituted glycyrrhetinic acid derivatives as inhibitors of cancer cells growth and NO production in LPS-activated J-774 cells
|
Salomatina, Oksana V.
|
|
2014
|
22 |
1 |
p. 585-593
9 p.
|
artikel
|
| 65 |
The phytoalexins brassilexin and camalexin inhibit cyclobrassinin hydrolase, a unique enzyme from the fungal pathogen Alternaria brassicicola
|
Pedras, M. Soledade C.
|
|
2014
|
22 |
1 |
p. 459-467
9 p.
|
artikel
|
| 66 |
The synthesis of novel taxoids for oral administration
|
Jing, Yun-rong
|
|
2014
|
22 |
1 |
p. 194-203
10 p.
|
artikel
|
| 67 |
Towards cytotoxic and selective derivatives of maslinic acid
|
Siewert, Bianka
|
|
2014
|
22 |
1 |
p. 594-615
22 p.
|
artikel
|
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