nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
Antitumor effects of ajulemic acid (CT3), a synthetic non-psychoactive cannabinoid 4 4 Abbreviations: AJA, ajulemic acid, dimethylheptyl-THC-11-oic acid; DG, diglyceride; FBS, fetal bovine serum; MEM, Minimum Essential Medium; MTT, microculture methyl-thiazolyl tetrazolium; PKC, protein kinase C; TEM, transmission electron microscopy; TG, triglyceride; and THC, tetrahydrocannabinol.
|
Recht, Lawrence D. |
|
2001 |
62 |
6 |
p. 755-763 9 p. |
artikel |
2 |
Chemoprotection from p53-dependent apoptosis: potential clinical applications of the p53 inhibitors 2 2 Abbreviations: CP, cyclophosphamide; PFT, pifithrin-α or p53 inhibitor; HT, hyperthermia; HS, heat shock; HO, hypoxia; and HIF-1, hypoxia inducible factor.
|
Komarova, Elena A. |
|
2001 |
62 |
6 |
p. 657-667 11 p. |
artikel |
3 |
Comparison of the mutant frequencies and mutation spectra of three non-genotoxic carcinogens, oxazepam, phenobarbital, and Wyeth 14,643, at the λcII locus in Big Blue® transgenic mice 2 2 Abbreviations: OX, oxazepam; PHE, phenobarbital; WY, Wyeth 14,643; PCR, polymerase chain reaction; MF, mutant frequency; MS, mutation spectrum; TMX, tamoxifen; and DMN, dimethylnitrosamine.
|
Singh, Vijaypreet K. |
|
2001 |
62 |
6 |
p. 685-692 8 p. |
artikel |
4 |
Differential signalling of both wild-type and Thr343Arg dopamine D2short receptor by partial agonists in a G-protein-dependent manner 1 1 Abbreviations: NPA, propylnorapomorphine; PTX, Bordetella pertussis toxin; 7-OH-DPAT, 7-(hydroxy-2-(di-n-propylamino)tetralin; and (+)-UH 232, cis-(+)-5-methoxy-1-methyl-2-(di-n-propylamino)tetralin.
|
Pauwels, Petrus J. |
|
2001 |
62 |
6 |
p. 723-732 10 p. |
artikel |
5 |
Effects of miltefosine on various biochemical parameters in a panel of tumor cell lines with different sensitivities 2 2 Abbreviations: D-21266, octadecyl-(N,N-dimethyl-piperidino-4-yl)-phosphate; HeLa-WT, HeLa wild-type cells, HeLa-MDR1-G185, HeLa-WT cells transfected with a wild-type MDR1 gene containing glycine in position 185; HeLa-MDR1-V185, HeLa wild-type cells transfected with a mutant MDR1 gene containing valine in position 185; HL-60, human promyelocytic leukemia cells; MDR1, multidrug resistance gene 1; MRP1, multidrug resistance-associated protein; miltefosine, hexadecylphosphocholine; PGP, P-170-glycoprotein; and TMA-DPH, trimethylamino-diphenylhexatriene.
|
Rybczynska, Maria |
|
2001 |
62 |
6 |
p. 765-772 8 p. |
artikel |
6 |
Identification of a 43-kDa protein in human liver cytosol that binds to the 3′-untranslated region of CYP2A6 mRNA 1 1 Abbreviations: Abbreviations: 39-UTR, 39-untranslated region; CYP, cytochrome P450; EMSA, electrophoretic mobility shift assay; HBV, hepatitis B virus; HCV, hepatitis C virus; hnRNP, heterogenous nuclear ribonucleoprotein; pBS, pBluescript; PCR, polymerase chain reaction; and TBE, Tris-borate-EDTA.
|
Gilmore, James |
|
2001 |
62 |
6 |
p. 669-678 10 p. |
artikel |
7 |
Increase in hepatic expression of SREBP-2 by gemfibrozil administration to rats 1 1 Abbreviations: ACO, acyl-CoA oxidase; Apo, apolipoprotein; APRT, adenosyl phosphoribosyl transferase; CT, CTP:phosphocholine cytidylyl transferase; HDL, high-density lipoprotein; HMG-CoA Rd, 3-hydroxy-3-methyl-glutaryl coenzyme A reductase; LDL, low-density lipoprotein; PAP, phosphatidate phosphohydrolase; PPARα, peroxisome proliferator-activated receptor; SREBP, sterol regulatory element binding protein; and VLDL, very-low-density lipoprotein.
|
Roglans, Núria |
|
2001 |
62 |
6 |
p. 803-809 7 p. |
artikel |
8 |
Inhibition of extracellular Ca2+ entry by YC-1, an activator of soluble guanylyl cyclase, through a cyclic GMP-independent pathway in rat neutrophils 1 1 Abbreviations: CO, carbon monoxide; CPA, cyclopiazonic acid; fMLP, formyl-methionyl-leucyl-phenylalanine; HBSS, Hanks’ balanced salt solution; IP3, inositol 1,4,5-trisphosphate; NO, nitric oxide; PKC, protein kinase C; PKG, cyclic GMP-dependent protein kinase; PLC, phospholipase C; PMA, phorbol 12-myristate 13-acetate; Rp-8-pCPT-cGMPS, 8-(4-chlorophenylthio)guanosine-3′,5′-monophosphorothioate, Rp-isomer; sGC, soluble guanylyl cyclase; and SNP, sodium nitroprusside.
|
Wang, Jih-Pyang |
|
2001 |
62 |
6 |
p. 679-684 6 p. |
artikel |
9 |
Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-κB 1 1 Abbreviations: Con A, concanavalin A; HBSS, Hanks’ balanced salt solution; IL, interleukin; iNOS, inducible nitric oxide synthase; LPS, lipopolysaccharide; NF-κB, nuclear factor kappaB; NO, nitric oxide; PEC, mouse peritoneal exsudate cell; TNF-α, tumor necrosis factor α; and Sl(s), sesquiterpene lactone(s).
|
Koch, Egon |
|
2001 |
62 |
6 |
p. 795-801 7 p. |
artikel |
10 |
MDR1 bicistronic vectors: analysis of selection stringency, amplified gene expression, and vector stability in cell lines 2 2 Abbreviations: MDR1, human multidrug resistance-1 gene; Pgp, P-glycoprotein; neo, bacterial neomycin resistance gene; PCR, polymerase chain reaction; and NPT, neomycin phosphotransferase.
|
Kane, Susan E |
|
2001 |
62 |
6 |
p. 693-704 12 p. |
artikel |
11 |
Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB 1 1 Abbreviations: A549 cells, human alveolar epithelial type II cell line; AP-1, activator protein-1; BSO; dl-buthionine (SR)-sulfoximine; COPD, chronic obstructive pulmonary disease; DMEM, Dulbecco’s modified Eagle’s medium; DTT, dithiothreitol; GSHMEE, glutathione monoethyl ester; H2O2, hydrogen peroxide; IkB, inhibitory binding protein kB; LDH, lactic dehydrogenase; NAC, N-acetyl-l-cysteine; NF-kB, nuclear factor-kappa b; NPSH, non-protein sulphydryls; PKC, protein kinase C; and ROS, reactive oxygen species.
|
Rahman, Irfan |
|
2001 |
62 |
6 |
p. 787-794 8 p. |
artikel |
12 |
Oxidative stress in rheumatoid arthritis leukocytes: suppression by rutin and other antioxidants and chelators 1 1 Abbreviations: CL, chemiluminescence; DF, desferrioxamine; DHR, dihydrorhodamine; FA, Fanconi anemia; HBSS, Hanks’ balanced salt solution; NMMA, N G-monomethyl l-arginine; NO, nitric oxide; PMA, 12-O-myristate 13-acetate; PMN, polymorphonuclear; RA, rheumatoid arthritis, and SOD, superoxide dismutase.
|
Ostrakhovitch, Elena A. |
|
2001 |
62 |
6 |
p. 743-746 4 p. |
artikel |
13 |
P450 interaction with farnesyl-protein transferase inhibitors metabolic stability, inhibitory potency, and P450 binding spectra in human liver microsomes 1 1 Abbreviations: FTI, farnesyl-protein transferase inhibitor; FTase, farnesyl-protein transferase; and LC-MS, liquid chromatography-mass spectrometry.
|
Chiba, Masato |
|
2001 |
62 |
6 |
p. 773-776 4 p. |
artikel |
14 |
Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450 2 2 Abbreviations: FMO, flavin-containing monooxygenase; CYP, cytochrome P450; KGM, keratinocyte growth medium; DMEM, Dulbecco’s modified Eagle’s medium.
|
Janmohamed, Azara |
|
2001 |
62 |
6 |
p. 777-786 10 p. |
artikel |
15 |
Relationships between non-occupational cadmium exposure and expression of nine cytochrome P450 forms in human liver and kidney cortex samples 1 1 Abbreviation: CYP, cytochrome P450.
|
Baker, Jason R. |
|
2001 |
62 |
6 |
p. 713-721 9 p. |
artikel |
16 |
Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes 1 1 Abbreviations: ADM, adriamycin; VP16, etoposide; Topo, topoisomerase; kDNA, knetoplast DNA; HCPT, hydrocamptothecin; SC, supercoiled form; RLX, relaxed form; LNR, linear form; and NC, nicked form.
|
Meng, Ling-hua |
|
2001 |
62 |
6 |
p. 733-741 9 p. |
artikel |
17 |
Suppression of cytokine production and neural cell death by the anti-inflammatory alkaloid cepharanthine: a potential agent against HIV-1 encephalopathy 1 1 Abbreviations: HIV-1, human immunodeficiency virus type 1; TNF, tumor necrosis factor; IL, interleukin; PMA, phorbol 12-myristate 13-acetate; FBS, fetal bovine serum; ROS, reactive oxygen species; NF-κB, nuclear factor κB; NAC, N-acetyl-l-cysteine; M/M, monocyte/macrophage; LPS, lipopolysaccharide; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PI, propidium iodide; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling; NO, nitric oxide; and HAART, highly active antiretroviral therapy.
|
Okamoto, Mika |
|
2001 |
62 |
6 |
p. 747-753 7 p. |
artikel |
18 |
tert-Butyl hydroperoxide-induced lipid signaling in hepatocytes: involvement of glutathione and free radicals 1 1 Abbreviations: [14C]-AA, [14C]-arachidonic acid; DCF, 2′,7′-dichlorofluorescein; DCFDA, 2′,7′-dichlorofluorescin diacetate; DTT, 1,4-dithiothreitol; MDA, malondialdehyde; PLA2, phospholipase A2; ROS, reactive oxygen species; TBARS, thiobarbituric acid reactive substances; and TBHP, tert-butyl hydroperoxide.
|
Martı́n, César |
|
2001 |
62 |
6 |
p. 705-712 8 p. |
artikel |
|