Effects of miltefosine on various biochemical parameters in a panel of tumor cell lines with different sensitivities 2 2 Abbreviations: D-21266, octadecyl-(N,N-dimethyl-piperidino-4-yl)-phosphate; HeLa-WT, HeLa wild-type cells, HeLa-MDR1-G185, HeLa-WT cells transfected with a wild-type MDR1 gene containing glycine in position 185; HeLa-MDR1-V185, HeLa wild-type cells transfected with a mutant MDR1 gene containing valine in position 185; HL-60, human promyelocytic leukemia cells; MDR1, multidrug resistance gene 1; MRP1, multidrug resistance-associated protein; miltefosine, hexadecylphosphocholine; PGP, P-170-glycoprotein; and TMA-DPH, trimethylamino-diphenylhexatriene.
Titel:
Effects of miltefosine on various biochemical parameters in a panel of tumor cell lines with different sensitivities 2 2 Abbreviations: D-21266, octadecyl-(N,N-dimethyl-piperidino-4-yl)-phosphate; HeLa-WT, HeLa wild-type cells, HeLa-MDR1-G185, HeLa-WT cells transfected with a wild-type MDR1 gene containing glycine in position 185; HeLa-MDR1-V185, HeLa wild-type cells transfected with a mutant MDR1 gene containing valine in position 185; HL-60, human promyelocytic leukemia cells; MDR1, multidrug resistance gene 1; MRP1, multidrug resistance-associated protein; miltefosine, hexadecylphosphocholine; PGP, P-170-glycoprotein; and TMA-DPH, trimethylamino-diphenylhexatriene.
Auteur:
Rybczynska, Maria Spitaler, Martin Knebel, Norbert G Boeck, Günther Grunicke, Hans Hofmann, Johann