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                                       Details van artikel 57 van 87 gevonden artikelen
 
 
  Role of Rosemary leaves extract against radiation-induced hematological and biochemical alterations in mice
 
 
Titel: Role of Rosemary leaves extract against radiation-induced hematological and biochemical alterations in mice
Auteur: Acharya Garima S.
Goyal Pradeep K.
Verschenen in: Nuclear technology & radiation protection
Paginering: Jaargang 23 (2008) nr. 2 pagina's 72-78
Jaar: 2008
Inhoud: The present paper is a study of the modulatory effect of Rosmarinus officinalis leaves extract on radiation-induced hematological and biochemical changes in Swiss albino mice. The dose reduction factor for the Rosemary extract against gamma rays was calculated 1.53 from LD50/30 values. The Rosemary extract was administered orally for 5 consecutive days prior to radiation exposure. The hematological and biochemical parameters were assessed from day 1 to 30 post-irradiation intervals. The total erythrocyte count, total leucocytes count, hemoglobin, and hematocrit values in the experimental group were found to be elevated as compared to the control group of mice. Furthermore, the Rosemary extract treatment enhanced reduced glutathione content in the liver and blood against radiation-induced depletion. Treatment with the plant extract brought a significant fall in the lipid peroxidation level, suggesting rosemary's role in protection against radiation-induced membrane and cellular damage. The results from the present study suggest a radio-protective effect of the Rosemary extract against radiation-induced hematological and biochemical alterations in mice.
Uitgever: VINČA Institute of Nuclear Sciences (provided by DOAJ)
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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