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                                       Details van artikel 8 van 26 gevonden artikelen
 
 
  Effect of Iron Repletion and Correction of Iron Deficiency on Thyroid Function in Iron-deficient Iranian Adolescent Girls
 
 
Titel: Effect of Iron Repletion and Correction of Iron Deficiency on Thyroid Function in Iron-deficient Iranian Adolescent Girls
Auteur: Mohammad Hassan Eftekhari
Mohammad Reza Eshraghian
Hassan Mozaffari-Khosravi
Navid Saadat
Farzad Shidfar
Verschenen in: Pakistan journal of biological sciences
Paginering: Jaargang 10 (2007) nr. 2 pagina's 255-260
Jaar: 2007
Inhoud: The aim of this study was to determine whether iron supplementation in iron-deficient adolescent girls would improve thyroid function. A double-blind clinical trial was performed in a region in southern I.R. Iran. A total of 103 iron deficient participants were chosen. In all, 94 participants successfully completed this study. Participants were randomly assigned to one of two groups and treated with a 300 mg ferrous sulfate 5 times/week (n = 47) and placebo 5 times/week (n = 47) for 12 weeks. Blood samples were collected and assayed for hemoglobin, hematocrit, serum ferritin, iron, total iron binding capacity (TIBC), Thyroid stimulating hormone (TSH), total thyroxine (TT4), total triiodothyronine (TT3), free thyroid hormones (FT4 and FT3), triiodothyronine resin uptake (T3RU), reverse triiodothyronine (rT3), selenium and albumin concentrations. Statistical analysis was performed with parametric and non-parametric methods as appropriate. Data analysis revealed a significant increase in TT4, TT3, T3RU and a significant decrease in rT3 concentration in comparison to initial values in iron treated group (12%, p<0.001; 3.5%, p<0.001; 16%, p<0.05 and 47%, p<0.001, respectively). At 12 week there were significant differences between control and placebo in TT4, TT3, T3RU and rT3 concentrations (9.9 vs 8.4 μg dL-1, 145.2 vs 130.4 μg dL-1, 32.5 vs 28.4% and 23 vs 41 μg dL-1, respectively, all p<0.001). Alterations in FT3 and TSH concentration were not significant, but concentration of FT4 revealed a significant difference between the beginning and the end of the study in iron treated group (10.3 vs 11.4, p<0.001). Iron supplementation improves some indices of thyroid function in iron-deficient adolescent girls.
Uitgever: Asian Network for Scientific Information (provided by DOAJ)
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

                             Details van artikel 8 van 26 gevonden artikelen
 
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