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| Titel: |
Semi-quantitative model of the gating of KcsA ion channel. 2. Dynamic self-organization model of the gating |
| Auteur: |
Kharkyanen V. N. Yesylevskyy S. O. Berezetskaya Boiteux C. Ramseyer Ch. |
| Verschenen in: |
Biopolymers and cell |
| Paginering: | Jaargang 25 (2009) nr. 6 pagina's 476-483 |
| Jaar: |
2009 |
| Inhoud: |
The aim of this series of papers is to develop the semi-quantitative theory of the gating of KcsA channel. Methods. For this purpose available structural and electrophysiological data and the results of molecular dynamics simulations were used in the context of the concept of dynamical self-organization. In the second paper we describe the principles of dynamic self-organization and develop the theory of KcsA channel gating based on this concept. Conclusions. Present work is the first successful attempt of combining the structure and dynamics of real protein and the general concept of dynamic self-organization |
| Uitgever: |
Institute of molecular biology and genetics, National Academy of Sciences of Ukraine (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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