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  Risk factors for severe ME/CFS
 
 
Titel: Risk factors for severe ME/CFS
Auteur: Derek Pheby
Verschenen in: Biology and medicine
Paginering: Jaargang 1 (2009) nr. 4 pagina's 50-74
Jaar: 2009
Inhoud: ME/CFS is a serious illness affecting several hundred thousand British people. Some 25% of people withME/CFS may be severely ill (housebound or bedbound), sometimes for decades. This observational,questionnaire-based study was designed to identify risk factors for severe disease. Exposure to potential riskfactors, including familial risks, personality, and early management of the illness, was compared in 124 peoplewith severe disease and 619 mildly ill controls. Severity was determined by self-report and the Barthel (activitiesof daily living) Index. Premorbid personality was assessed using the Neuroticism and Conscientiousnessdomains of the IPIP scale. Analysis was by tests of association and logistic regression. Early management of theillness appeared the most important determinant of severity. Having a mother with ME/CFS was also important.Smoking and personality were not risk factors, neurotic traits being more frequent among the less severely ill.Conscientiousness overall was not related to severity.
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Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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