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| Titel: |
Nutritional control of HIV-AIDS- A case for Selenium |
| Auteur: |
Parisa Kalantari Hema Vunta Umamaheswari D. Palempalli C. Channa Reddy Andrew J. Henderson K. Sandeep Prabhu |
| Verschenen in: |
American journal of infectious diseases |
| Paginering: | Jaargang 3 (2007) nr. 4 pagina's 195-201 |
| Jaar: |
2007 |
| Inhoud: |
Selenium (Se) is a micronutrient that is incorporated into proteins. Some of the selenoenzymes such as GPXs and thioredoxin reductases exhibit glutathione peroxidase-dependent activities towards organic and inorganic peroxides. Thus, selenoenzymes play a pivotal role inmitigating oxidative stress caused by accumulation of peroxides. In this respect, selenoproteins may interfere with the transcription-driven by oxidative stress-dependent signaling mechanisms to influencethe expression of redox sensitive genes, including inflammatory cytokines and HIV provirus. Several epidemiological studies support our view that Se supplementation affects transcription of HIV;however, the underlying mechanism is not elucidated. In this mini review, we consider the relationship between Se and HIV and propose possible mechanisms by which Se controls HIV transcription. |
| Uitgever: |
Science Publications (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 13 van 14 gevonden artikelen
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