Molecular Printing Using UV-Assisted Immobilization of Biomolecules
Titel:
Molecular Printing Using UV-Assisted Immobilization of Biomolecules
Auteur:
Skovsen, Esben Duroux, Meg Neves-Petersen, Maria Teresa Duroux, Laurent Petersen, Steffen Bjørn
Verschenen in:
International journal of optomechatronics
Paginering:
Jaargang 1 (2007) nr. 4 pagina's 383-391
Jaar:
2007-10
Inhoud:
UV light-assisted immobilization of biomolecules is a novel technology that is well suited for achieving spatially-localized covalent coupling of biomolecules onto thiol reactive surfaces, e.g., thiolated glass, silicon, or gold. The spatial resolution is defined by the area illuminated by the UV source. Thus, in principle, the limit will be the diffraction limit of the light. This enables printing of molecular arrays or other patterns onto a substrate with higher resolution and considerably faster than can be achieved by, e.g., micro-dispensing, where the minimum spot size depends on the physical size of the dispensed droplets.