Synthesis of new enolphosphates displaying biological activity
Title:
Synthesis of new enolphosphates displaying biological activity
Author:
Bodalski, R. Mikolajczyk, J. Zwierzak, A. Wroblewski, A. Markowicz, W. Koszuk, J. Kluba, M. Brylikowska-Piotrowicz, J.
Appeared in:
Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes
Paging:
Volume 18 (1983) nr. 4-5 pages 579-589
Year:
1983
Contents:
A series of new enolphosphates containing carboalkoxy or carbamoyl at the α-vinylic position and substituted with halophenyl groups at the β-carbon atom were synthesized by the Perkov reaction between trialkyl phosphites and suitable derivatives of pyruvic esters or amides. Biological screening of these compounds revealed different biological activity, when their regioisomers, in which the location of carboalkoxy (carbamoyl) residues in the molecule is reversed, were compared. Enolphosphates, as a class of compounds, are well recognized because of their biological activity1. Some of them are manufactured and used in pest control.