|
| << previous | next >> |
Journal description
All volumes of the corresponding journal
All issues of the corresponding volume
All articles of the corresponding issues
Details for article 14 of 18 found articles
| Title: | |
| Author: | |
| Appeared in: |
Analytical letters |
| Paging: | Volume 27 (1994) nr. 3 pages 561-582 |
| Year: |
1994-02-01 |
| Contents: |
Two stability-indicating methods, HPLC and derivative difference spectrophotometry, have been described for the determination of acetaminophen as well as its degradation product, 4-aminophenol. The former method is based on the selection of two chromatographic systems using an octadecylsilane (C18) stationary phase. The latter involves the use of derivative (first and second) difference spectrophotometric technique. Interference from the coformulated excipients (colorant, flavour, preservative) of liquid formulations is completely eliminated. Accuracy, precision and the limit of detection of 4-aminophenol are discussed. The proposed methods are applied for determination of acetaminophen and 4-aminophenol in pharmaceutical formulations. |
| Publisher: |
Taylor & Francis |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 14 of 18 found articles
| << previous | next >> |