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                                       Details van artikel 19 van 45 gevonden artikelen
 
 
  Measurement of Particle Distribution in Microchannel Flow Using a 3D-TIRFM Technique
 
 
Titel: Measurement of Particle Distribution in Microchannel Flow Using a 3D-TIRFM Technique
Auteur: Kanda, K.
Ogata, S.
Jingu, K.
Yang, M.
Verschenen in: Journal of visualization
Paginering: Jaargang 10 (2008) nr. 2 pagina's 207-215
Jaar: 2008-07-06
Inhoud: The presence of bio-substances in the near-wall region in micro bio-chemical analysis chips is an important topic but one which is difficult to investigate directly. In this paper we developed an accurate 3D-TIRFM technique, which was used to investigate the three-dimensional positions of nano-particles. The depth was calibrated using a piezo stage. As an example of an application of this technique, the concentration profile of nano-particles near a wall surface was investigated. The results showed that the concentration profile was non-uniform and lower than that in the bulk. In addition the ionic strength of the solvent strongly influenced the concentration profile. It was concluded that the non-uniform concentration profile is due to the influence of the electric double layer around the particles and the surface. This demonstrates the importance of selecting suitable electric characteristics, since a non-uniform and low concentration profile near the wall will affect the reaction efficiency and the sensitivity in micro bio-chemical analysis.
Uitgever: IOS Press
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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