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Details for article 19 of 45 found articles
| Title: |
Measurement of Particle Distribution in Microchannel Flow Using a 3D-TIRFM Technique |
| Author: |
Kanda, K. Ogata, S. Jingu, K. Yang, M. |
| Appeared in: |
Journal of visualization |
| Paging: | Volume 10 (2008) nr. 2 pages 207-215 |
| Year: |
2008-07-06 |
| Contents: |
The presence of bio-substances in the near-wall region in micro bio-chemical analysis chips is an important topic but one which is difficult to investigate directly. In this paper we developed an accurate 3D-TIRFM technique, which was used to investigate the three-dimensional positions of nano-particles. The depth was calibrated using a piezo stage. As an example of an application of this technique, the concentration profile of nano-particles near a wall surface was investigated. The results showed that the concentration profile was non-uniform and lower than that in the bulk. In addition the ionic strength of the solvent strongly influenced the concentration profile. It was concluded that the non-uniform concentration profile is due to the influence of the electric double layer around the particles and the surface. This demonstrates the importance of selecting suitable electric characteristics, since a non-uniform and low concentration profile near the wall will affect the reaction efficiency and the sensitivity in micro bio-chemical analysis. |
| Publisher: |
IOS Press |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 19 of 45 found articles
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