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| Titel: |
Effect of parent artery expansion by stent placement in cerebral aneurysms |
| Auteur: |
Mori, Futoshi Hanida, Sho Ohta, Makoto Matsuzawa, Teruo |
| Verschenen in: |
Technology & health care |
| Paginering: | Jaargang 22 (2014) nr. 2 pagina's 209-223 |
| Jaar: |
2014-06-04 |
| Inhoud: |
BACKGROUND: Stent placement for cerebral aneurysms leads to a decrease in blood flow. This occurs not only through the direct obstruction of flow but also by the expansion of the parent artery. The latter has been observed in several clinical studies. OBJECTIVE: The goal of this study was to clarify the effects of parent artery expansion after stent treatment on the following: 1) decrease in blood flow to an aneurysm, 2) wall shear stress (WSS), and 3) oscillatory shear index (OSI). METHODS: The parent artery geometry constructed U-shape. The aneurysm location with respect to the U-shaped parent artery was determined according to previous clinical data. We performed calculations in unsteady-state situations using constructed models. RESULTS: Parent artery expansion with stent reduces blood inflow to an aneurysm and WSS of the aneurysm wall, in addition to increasing OSI. The aneurysm position affects the decrease of the inflow rate and WSS ratio and increases the OSI ratio. Expansion causes the majority of effects on flow reduction inside an aneurysm model. Thus, the expansion effects of all samples should not be neglected. CONCLUSION: These data suggest that parent artery expansion and its effect should be measured and included in the total decrease in blood flow. Parent artery expansion may induce intimal hyperplasia, thus increasing the thickness of the aneurysm wall. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 8 van 13 gevonden artikelen
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