Oxidation of prostaglandin H2 and prostaglandin H2 analogues by human cytochromes P450: analysis of ω-side chain hydroxy metabolites and four steroisomers of 5-hydroxyprostaglandin I1 by mass spectrometry 1 1 Abbreviations: CYP, cytochrome P450; HHT, (12S)-hydroxy-5Z,8Z,10E-heptadecatrienoic acid; MDA, malondialdehyde; MS/MS, tandem mass spectrometry; PG, prostaglandin; PGI2, prostacyclin; and TX, thromboxane.
Titel:
Oxidation of prostaglandin H2 and prostaglandin H2 analogues by human cytochromes P450: analysis of ω-side chain hydroxy metabolites and four steroisomers of 5-hydroxyprostaglandin I1 by mass spectrometry 1 1 Abbreviations: CYP, cytochrome P450; HHT, (12S)-hydroxy-5Z,8Z,10E-heptadecatrienoic acid; MDA, malondialdehyde; MS/MS, tandem mass spectrometry; PG, prostaglandin; PGI2, prostacyclin; and TX, thromboxane.