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μ Opioid receptor-mediated G-protein activation by heroin metabolites: evidence for greater efficacy of 6-monoacetylmorphine compared with morphine 1 1 Abbreviations: 6-MAM, 6-monoacetylmorphine; GTPγS, guanosine-5′-O-(γ-thio)-triphosphate; DAMGO, [d-Ala2,(N-Me)Phe4,Gly5(OH)]enkephalin; M-6-G, morphine-6-βd-glucuronide; and hMOR-C6, C6 rat glioma cells expressing human μ opioid receptors. |
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Titel: |
μ Opioid receptor-mediated G-protein activation by heroin metabolites: evidence for greater efficacy of 6-monoacetylmorphine compared with morphine 1 1 Abbreviations: 6-MAM, 6-monoacetylmorphine; GTPγS, guanosine-5′-O-(γ-thio)-triphosphate; DAMGO, [d-Ala2,(N-Me)Phe4,Gly5(OH)]enkephalin; M-6-G, morphine-6-βd-glucuronide; and hMOR-C6, C6 rat glioma cells expressing human μ opioid receptors. |
Auteur: |
Selley, Dana E. Cao, Cheng-Chun Sexton, Tammy Schwegel, Jennifer A. Martin, Thomas J. Childers, Steven R. |
Verschenen in: |
Biochemical pharmacology |
Paginering: |
Jaargang 62 (2001) nr. 4 pagina's 9 p. |
Jaar: |
2001 |
Inhoud: |
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Uitgever: |
Elsevier Science Inc. |
Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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