|
| << vorige | volgende >> |
Tijdschrift beschrijving
Alle jaargangen van het bijbehorende tijdschrift
Alle afleveringen van het bijbehorende jaargang
Alle artikelen van de bijbehorende aflevering
Details van artikel 4 van 7 gevonden artikelen
| Titel: |
Comparison of steroidal synthetic agents cytolytic toward Florida red tide organism (Gymnodinium breve, Ptychodiscus brevis) |
| Auteur: |
Martin, Dean F. Krumrei, Thomas N. Moon, Ralph E. |
| Verschenen in: |
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering |
| Paginering: | Jaargang 15 (1980) nr. 1 pagina's 37-44 |
| Jaar: |
1980 |
| Inhoud: |
Analysis of a natural control agent for the red tide organism (G. breve, P. brevis) indicated the presence of sterols as an active, or adventitious component of a cytolytic mixture elaborated by the cyanobacterium Gomphosphaeria aponina Kutzing. Comparisons of several plant sterols showed cholesta-5,7-dien-3ss-ol (7-dehydrocholesterol) was cytolytically active toward G. breve. Derivatives of cholesta-5,7-dien-3ss-ol and cholest-5-en-3ss-ol (7-dehydrocholesterol and cholesterol) were prepared to enhance water solubility. Derivatives of the type ROCO(CH2)4CO(OCH2CH2)nOH varied markedly in cytolytic activity with G. breve as the bioassay organism. The derivative of cholest-5en-3ss-ol (cholesterol) (n = 12.5) showed no discernable cytolytic activity up to 20 ppm, but the cholesta-5,7-dien-3ss-ol (7-dehydrocholesterol) derivatives (n = 22, 12.5, or 4) were cytolytic at about 5 ppm and had a dose-dependent response. Implications of the observations are considered. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 4 van 7 gevonden artikelen
| << vorige | volgende >> |