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                             71 results found
no title author magazine year volume issue page(s) type
1 Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform Moraes, Carolina B.
2019
3 p. 346-361
article
2 A Cell-Based Assay to Investigate Hypolipidemic Effects of Nonalcoholic Fatty Liver Disease Therapeutics Dave, Tapan
2018
3 p. 274-282
article
3 A Comparative Study of Target Engagement Assays for HDAC1 Inhibitor Profiling Asawa, Rosita R.

3 p. 253-264
article
4 Activity and inhibition of the SARS-CoV-2 Omicron nsp13 R392C variant using RNA duplex unwinding assays Inniss, Nicole L.

3 p.
article
5 A 3D Heterotypic Multicellular Tumor Spheroid Assay Platform to Discriminate Drug Effects on Stroma versus Cancer Cells Weydert, Zoe

3 p. 265-276
article
6 A High-Throughput Screening Strategy for Development of RNF8-Ubc13 Protein–Protein Interaction Inhibitors Weber, Elisabeth
2017
3 p. 316-323
article
7 Aldehyde Dehydrogenase 2 (ALDH2): A novel sorafenib target in hepatocellular carcinoma unraveled by the proteome-wide cellular thermal shift assay Ferreira, Inês C.

3 p.
article
8 A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia Siva, Kavitha
2019
3 p. 304-313
article
9 A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities McManus, Jessica
2018
3 p. 264-273
article
10 A Simple and Sensitive High-Content Assay for the Characterization of Antiproliferative Therapeutic Antibodies Stengl, Andreas
2017
3 p. 309-315
article
11 Automated quality control tool for high-content imaging data by building 2D prediction intervals on reference biosignatures Assefa, Alemu Takele

3 p. 111-117
article
12 Automating Complex, Multistep Processes on a Single Robotic Platform to Generate Reproducible Phosphoproteomic Data Mullis, B. Todd

3 p. 277-286
article
13 Biologically Relevant Heterogeneity: Metrics and Practical Insights Gough, Albert
2017
3 p. 213-237
article
14 Bioluminescent High-Throughput Succinate Detection Method for Monitoring the Activity of JMJC Histone Demethylases and Fe(II)/2-Oxoglutarate-Dependent Dioxygenases Alves, Juliano
2018
3 p. 242-254
article
15 Covalent hits and where to find them Lucas, Simon C.C.

3 p.
article
16 CRISPR: A Screener’s Guide le Sage, Carlos

3 p. 233-240
article
17 deepOrganoid: A brightfield cell viability model for screening matrix-embedded organoids Powell, Reid T.

3 p. 175-184
article
18 Design of High-Throughput Screening of Natural Extracts to Identify Molecules Bypassing Primary Coenzyme Q Deficiency in Saccharomyces cerevisiae Berenguel Hernández, Aida M.

3 p. 299-309
article
19 Design of the LifeArc Index Set and Retrospective Review of Its Performance: A Collection for Sharing Birchall, Kristian
2019
3 p. 332-345
article
20 Developing recombinant antibodies by phage display technology to neutralize viral infectious diseases Mustafa, Mujahed I.

3 p.
article
21 Development of a High-Throughput Screening-Compatible Assay for Discovery of GPR3 Inverse Agonists Using a cAMP Biosensor Ayukawa, Kumiko

3 p. 287-298
article
22 Development of an Inhibitor Screening Assay for Mono-ADP-Ribosyl Hydrolyzing Macrodomains Using AlphaScreen Technology Haikarainen, Teemu
2018
3 p. 255-263
article
23 Development of high-throughput lacrimal gland organoid platforms for drug discovery in dry eye disease Rodboon, Teerapat

3 p. 151-158
article
24 Discovery and Characterization of Chemical Compounds That Inhibit the Function of Aspartyl-tRNA Synthetase from Pseudomonas aeruginosa Corona, Araceli
2018
3 p. 294-301
article
25 Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays Otvos, Reka A.
2019
3 p. 362-385
article
26 3D-Suspension culture platform for high throughput screening of neurotoxic chemicals using LUHMES dopaminergic neurons Tong, Zhi-Bin

3 p.
article
27 Epithelial 3D-spheroids as a tool to study air pollutant-induced lung pathology Baarsma, Hoeke A.

3 p. 185-190
article
28 Establishment, optimization and validation of a fluorescence polarization-based high-throughput screening assay targeting cathepsin L inhibitors Zhou, Wenwen

3 p.
article
29 EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology Brennecke, Philip
2019
3 p. 398-413
article
30 Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines Warchal, Scott J.
2019
3 p. 224-233
article
31 FLECS technology for high-throughput screening of hypercontractile cellular phenotypes in fibrosis: A function-first approach to anti-fibrotic drug discovery Wang, Yao

3 p.
article
32 Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes Wigle, Tim J.

3 p. 241-252
article
33 Generation of a Monoclonal Antibody against D-Dimer Using HTS-Based LiCA Dong, Yuan

3 p. 310-319
article
34 Genome-Wide Overexpression Screen Identifies Genes Able to Bypass p16-Mediated Senescence in Melanoma Lee, Won Jae
2017
3 p. 298-308
article
35 High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy Tufi, Roberta

3 p. 73-87
article
36 High-Density Cell Arrays for Genome-Scale Phenotypic Screening Starkuviene, Vytaute
2019
3 p. 274-283
article
37 High throughput assay for compounds that boost BDNF expression in neurons Liao, Guey-Ying

3 p. 88-94
article
38 High-throughput method to analyze the cytotoxicity of CAR-T Cells in a 3D tumor spheroid model using image cytometry Zurowski, David

3 p. 65-72
article
39 High-throughput nephelometry methodology for qualitative determination of aqueous solubility of chemical libraries Brea, Jose

3 p.
article
40 High-Throughput Screening Assays for Cancer Immunotherapy Targets: Ectonucleotidases CD39 and CD73 Kumar, Meera

3 p. 320-326
article
41 High throughput screening for drugs that inhibit 3C-like protease in SARS-CoV-2 Smith, Emery

3 p. 95-101
article
42 High throughput screening of 0.5 million compounds against CRAF using Alpha CETSAⓇ Rowlands, Hannah

3 p. 102-110
article
43 High-Throughput Spectral and Lifetime-Based FRET Screening in Living Cells to Identify Small-Molecule Effectors of SERCA Schaaf, Tory M.
2017
3 p. 262-273
article
44 Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen Visperas, Patrick R.
2017
3 p. 324-331
article
45 Implementation of the NCI-60 Human Tumor Cell Line Panel to Screen 2260 Cancer Drug Combinations to Generate >3 Million Data Points Used to Populate a Large Matrix of Anti-Neoplastic Agent Combinations (ALMANAC) Database Close, David A.
2019
3 p. 242-263
article
46 Inexpensive High-Throughput Screening of Kinase Inhibitors Using One-Step Enzyme-Coupled Fluorescence Assay for ADP Detection Imamura, Riyo Maruki
2019
3 p. 284-294
article
47 Integrated Multiparametric High-Content Profiling of Endothelial Cells Wiseman, Erika
2019
3 p. 264-273
article
48 Jenkins-CI, an Open-Source Continuous Integration System, as a Scientific Data and Image-Processing Platform Moutsatsos, Ioannis K.
2017
3 p. 238-249
article
49 Lead identification using 3D models of pancreatic cancer Fernandez-Vega, Virneliz

3 p. 159-166
article
50 Live cell painting: New nontoxic dye to probe cell physiology in high content screening Cottet, Martin

3 p.
article
51 Mass spectrometry-based proteomics of 3D cell culture: A useful tool to validate culture of spheroids and organoids Avelino, Thayna Mendonca

3 p. 167-174
article
52 Micro/nano topological modification of TiO2 nanotubes activates Thy-1 signaling to control osteogenic differentiation of stem cells Jinsheng, Li

3 p.
article
53 Multifunctional profiling of triple-negative breast cancer patient-derived tumoroids for disease modeling Cromwell, Evan F

3 p. 191-200
article
54 Nanofractionation Platform with Parallel Mass Spectrometry for Identification of CYP1A2 Inhibitors in Metabolic Mixtures Zietek, Barbara M.
2018
3 p. 283-293
article
55 Novel Chemical Scaffolds for Inhibition of Rifamycin-Resistant RNA Polymerase Discovered from High-Throughput Screening Scharf, Nathan T.
2017
3 p. 287-297
article
56 Patient-Derived Phenotypic High-Throughput Assay to Identify Small Molecules Restoring Lysosomal Function in Tay–Sachs Disease Colussi, Dennis J.
2019
3 p. 295-303
article
57 Protocol for high throughput 3D drug screening of patient derived melanoma and renal cell carcinoma Ortiz Jordan, Luis M.

3 p.
article
58 Protocol for kinetic mode potassium channel assays on common plate readers and microscopes Smith, Emery

3 p.
article
59 Real-time thiol detection in iPSC-derived neuron cultures using SemKur-IM, a novel fluorescent dithio probe Alvarez, Roxanne

3 p.
article
60 Reviewer List 2019
3 p. 414-415
article
61 Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery D’Agostino, Vito Giuseppe
2019
3 p. 314-331
article
62 SLAS special issue editorial 2022: 3D cell culture approaches of microphysiologically relevant models Souza, Glauco R.

3 p. 149-150
article
63 Spectral Unmixing Plate Reader: High-Throughput, High-Precision FRET Assays in Living Cells Schaaf, Tory M.
2017
3 p. 250-261
article
64 The Academic Pill: How Academia Contributes to Curing Diseases Bickle, Marc
2019
3 p. 203-212
article
65 The CellRaft AIRⓇ system: A novel system enabling organoid imaging, identification, and isolation Stern, Allysa

3 p. 201-208
article
66 The Scripps Molecular Screening Center and Translational Research Institute Baillargeon, Pierre
2019
3 p. 386-397
article
67 Unbiased Phenotype Detection Using Negative Controls Janosch, Antje
2019
3 p. 234-241
article
68 Upscaling of hiPS Cell–Derived Neurons for High-Throughput Screening Traub, Stefanie
2017
3 p. 274-286
article
69 Using chemical and biological data to predict drug toxicity Liu, Anika

3 p. 53-64
article
70 Using Microscale Thermophoresis to Characterize Hits from High-Throughput Screening: A European Lead Factory Perspective Rainard, Julie M.
2018
3 p. 225-241
article
71 xCELLanalyzer: A Framework for the Analysis of Cellular Impedance Measurements for Mode of Action Discovery Franke, Raimo
2019
3 p. 213-223
article
                             71 results found
 
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