| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Achieving human brain exposure with the oral ataxia-telangiectasia mutated kinase inhibitor AZD1390, a substrate of aldehyde oxidase
|
Colclough, Nicola
|
|
|
53 |
8 |
p.
|
artikel
|
| 2 |
Age-dependent pharmacokinetics of nifedipine in spontaneous hypertensive rats are associated with changes in gut microbiota and hepatic CYP3A1 expression
|
Xiong, Yalan
|
|
|
53 |
8 |
p.
|
artikel
|
| 3 |
CYP1A2 expression and activity in a large panel of human nonneoplastic surgical liver samples: Influence of genetics, lifestyle, and other factors
|
Kuhn, Urs Dieter
|
|
|
53 |
8 |
p.
|
artikel
|
| 4 |
Differential protein expressions of hepatic drug-metabolizing enzymes between White and Black Americans and the associated genetic polymorphisms
|
Jung, Sun Min
|
|
|
53 |
8 |
p.
|
artikel
|
| 5 |
Early-stage prediction of human intestinal metabolism from in vitro liver microsomal clearance
|
Arey, Ryan
|
|
|
53 |
8 |
p.
|
artikel
|
| 6 |
Establishment of a novel predictive model for thiopurine-induced leucopenia based on the polymorphisms in the DNA-thioguanine nucleotide metabolite pathway in Chinese patients with inflammatory bowel disease
|
Zhu, Xia
|
|
|
53 |
8 |
p.
|
artikel
|
| 7 |
Evaluation of various experimental conditions and mechanistic static versus dynamic models to predict time-dependent CYP3A4/5 inhibition potential of drugs
|
Justine, Badée
|
|
|
53 |
8 |
p.
|
artikel
|
| 8 |
Human metabolism of zamicastat, an oral dopamine β-hydroxylase inhibitor
|
Loureiro, Ana Isabel
|
|
|
53 |
8 |
p.
|
artikel
|
| 9 |
Hydroxylation near the epoxyketone of carfilzomib confers protection from microsomal epoxide hydrolase-mediated metabolism
|
Lee, Seongsoo
|
|
|
53 |
8 |
p.
|
artikel
|
| 10 |
Impact of cytosolic aldehyde oxidase contamination in liver microsomes on intrinsic clearance estimations
|
Tang, Lloyd Wei Tat
|
|
|
53 |
8 |
p.
|
artikel
|
| 11 |
Kinetic and mechanistic investigation toward the characterization of tucatinib inhibition of CYP3A4
|
Sun, Hao
|
|
|
53 |
8 |
p.
|
artikel
|
| 12 |
Nonclinical absorption, distribution, metabolism, excretion and biomarkers properties of a modified N-acetylgalactosamine–conjugated small-interfering RNA for hypercholesteremia
|
Dou, Dehu
|
|
|
53 |
8 |
p.
|
artikel
|
| 13 |
Pharmacodynamic determinants of mitochondrial one-carbon flux and serine hydroxymethyltransferase inhibition in human tumors
|
Schneider, Mathew
|
|
|
53 |
8 |
p.
|
artikel
|
| 14 |
Physiologically based pharmacokinetic modeling of aldehyde oxidase drug-drug interactions mediated by erlotinib
|
Heikkinen, Aki T.
|
|
|
53 |
8 |
p.
|
artikel
|
| 15 |
Regulation of expression and activity of hepatic transporters by pregnancy-related hormones in HepaRG cells
|
Sharma, Sejal
|
|
|
53 |
8 |
p.
|
artikel
|
| 16 |
The application of mechanistic absorption, distribution, metabolism and excretion studies and physiologically-based pharmacokinetic modeling in the discovery of the next-generation oral selective estrogen receptor degrader camizestrant to achieve an acceptable human pharmacokinetic profile
|
Gangl, Eric T.
|
|
|
53 |
8 |
p.
|
artikel
|
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