| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Assessing granisetron as a specific CYP1A1 substrate in primary human hepatocytes: A comprehensive evaluation for drug development studies
|
Lenich, Ann-Kathrin
|
|
|
53 |
4 |
p.
|
artikel
|
| 2 |
Corrigendum to “Pharmacokinetic/Pharmacodynamic Assessment of the Structural Refinement of Clopidogrel Focusing on the Balance between Bioactivation and Deactivation”
|
|
|
|
53 |
4 |
p.
|
artikel
|
| 3 |
CYP1A2 contributes to the metabolism of mefloquine: Exploration using in vitro metabolism and physiologically-based pharmacokinetic modelling
|
Cloete, Cleavon K.
|
|
|
53 |
4 |
p.
|
artikel
|
| 4 |
Development of human embryonic stem cell-derived cardiomyocytes and application of fluorescence probe substrate for characterization of cytochrome P450 enzyme 2J2
|
Zhu, Xingyu
|
|
|
53 |
4 |
p.
|
artikel
|
| 5 |
Evaluation of small interfering RNA–dependent knockdowns of drug-metabolizing enzymes in multiwell array culture of primary human hepatocyte spheroids for estimation of fraction metabolized
|
Brücker, Lena
|
|
|
53 |
4 |
p.
|
artikel
|
| 6 |
Impact of the loss of slc43a3 on 6-mercaptopurine absorption and tissue distribution in mice
|
Sayler, Aaron L.
|
|
|
53 |
4 |
p.
|
artikel
|
| 7 |
Improved clearance predictions for aldehyde oxidase substrates using a novel triculture human hepatocyte model
|
Byer-Alcorace, Alexander
|
|
|
53 |
4 |
p.
|
artikel
|
| 8 |
In vitro–in vivo scaling of cytochrome P450-mediated metabolic clearance using a relative activity factor approach
|
Nagaya, Yoko
|
|
|
53 |
4 |
p.
|
artikel
|
| 9 |
Novel O-methylpyrimidine prodrugs of phenolic compounds bioactivated by aldehyde oxidase: Enhancing metabolic stability against first-pass conjugative metabolism in the intestine
|
Kowalski, John P.
|
|
|
53 |
4 |
p.
|
artikel
|
| 10 |
Prediction of hepatic metabolic clearance in rats and dogs using long-term cocultured hepatocytes
|
Umehara, Kenichi
|
|
|
53 |
4 |
p.
|
artikel
|
| 11 |
Quantitative clinical risk assessment of CYP2C, UDP-glucuronosyltransferase, P-glycoprotein induction, and complex drug-drug interactions using TruVivo human hepatocyte triculture platform
|
Ramsden, Diane
|
|
|
53 |
4 |
p.
|
artikel
|
| 12 |
Quantitative prediction of drug disposition for uridine diphosphate-glucuronosyltransferase substrates using humanized mice
|
Miyake, Taiji
|
|
|
53 |
4 |
p.
|
artikel
|
| 13 |
Significance of gut breast cancer resistance protein versus organic anion transporting polypeptide 2B1 inhibition on rosuvastatin clinical drug-drug interactions
|
West, Mark A.
|
|
|
53 |
4 |
p.
|
artikel
|
| 14 |
Species-specific in vivo exposure assessment and in vivo-in vitro correlation of the carboxylate esters prodrug HD56 targeting FK506 binding proteins: The pivotal role of humanized mice
|
Yang, Mengmeng
|
|
|
53 |
4 |
p.
|
artikel
|
| 15 |
Switch/sucrose non-fermentable complex interacts with constitutive androstane receptor to regulate drug-metabolizing enzymes and transporters in the liver
|
Kurosawa, Kiamu
|
|
|
53 |
4 |
p.
|
artikel
|
Tijdschrift beschrijving