| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
Absolute membrane protein abundance of P-glycoprotein, breast cancer resistance protein, and multidrug resistance proteins in term human placenta tissue and commonly used cell systems: Application in physiologically based pharmacokinetic modeling of placental drug disposition
|
Al-Majdoub, Zubida M.
|
|
|
53 |
1 |
p.
|
artikel
|
| 2 |
Characterization of human alcohol dehydrogenase 4 and aldehyde dehydrogenase 2 as enzymes involved in the formation of 5-carboxylpirfenidone, a major metabolite of pirfenidone
|
Sato, Rei
|
|
|
53 |
1 |
p.
|
artikel
|
| 3 |
Comparative analysis of the physiological and transport functions of various sources of renal proximal tubule cells under static and fluidic conditions in PhysioMimix T12 platform
|
Sakolish, Courtney
|
|
|
53 |
1 |
p.
|
artikel
|
| 4 |
Efflux transporters in drug disposition during pregnancy
|
Chen, Xin
|
|
|
53 |
1 |
p.
|
artikel
|
| 5 |
Environmentally persistent free radicals stimulate CYP2E1-mediated generation of reactive oxygen species at the expense of substrate metabolism
|
Cawley, George F.
|
|
|
53 |
1 |
p.
|
artikel
|
| 6 |
Heterotropic allosteric modulation of CYP3A4 in vitro by progesterone: Evidence for improvement in prediction of time-dependent inhibition for macrolides
|
Rougée, Luc R.A.
|
|
|
53 |
1 |
p.
|
artikel
|
| 7 |
Human enteroid monolayers: A novel, functionally stable model for investigating oral drug disposition
|
Arian, Christopher
|
|
|
53 |
1 |
p.
|
artikel
|
| 8 |
Impact of genetic polymorphisms and drug-drug interactions mediated by carboxylesterase 1 on remimazolam deactivation
|
Wang, Zhuo
|
|
|
53 |
1 |
p.
|
artikel
|
| 9 |
Intestine versus liver? Uncovering the hidden major metabolic organs of silybin in rats
|
Sun, Yuanbo
|
|
|
53 |
1 |
p.
|
artikel
|
| 10 |
Isoform-level expression of the constitutive androstane receptor (CAR or NR1I3) transcription factor better predicts the mRNA expression of the cytochrome P450s in human liver samples
|
Collins, Joseph M.
|
|
|
53 |
1 |
p.
|
artikel
|
| 11 |
Pharmacokinetics and absorption, distribution, metabolism and excretion profiling of tanimilast following an intravenous 14C-microtracer coadministered with an inhaled dose in healthy male individuals
|
Bassi, Michele
|
|
|
53 |
1 |
p.
|
artikel
|
| 12 |
Physiologically based pharmacokinetic modeling of small molecules: How much progress have we made?
|
Isoherranen, Nina
|
|
|
53 |
1 |
p.
|
artikel
|
| 13 |
Potential and challenges in application of physiologically based pharmacokinetic modeling in predicting diarrheal disease impact on oral drug pharmacokinetics
|
Zhang, Cindy X.
|
|
|
53 |
1 |
p.
|
artikel
|
| 14 |
Real-world application of physiologically based pharmacokinetic models in drug discovery
|
Santos, Laura G.A.
|
|
|
53 |
1 |
p.
|
artikel
|
| 15 |
The absorption, distribution, metabolism and elimination characteristics of small interfering RNA therapeutics and the opportunity to predict disposition in pregnant women
|
Amaeze, Ogochukwu
|
|
|
53 |
1 |
p.
|
artikel
|
| 16 |
Uncovering the impact of COVID-19–mediated bidirectional dysregulation of cytochrome P450 3A4 on systemic and pulmonary drug concentrations using physiologically based pharmacokinetic modeling
|
Nwabufo, Chukwunonso K.
|
|
|
53 |
1 |
p.
|
artikel
|
| 17 |
Utility of physiologically based pharmacokinetic modeling in predicting and characterizing clinical drug interactions
|
Foti, Robert S.
|
|
|
53 |
1 |
p.
|
artikel
|
| 18 |
Utilization of a human Liver Tissue Chip for drug-metabolizing enzyme induction studies of perpetrator and victim drugs
|
Ohri, Shivam
|
|
|
53 |
1 |
p.
|
artikel
|
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