Digitale Bibliotheek
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                             103 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A bacterial actin with high ATPase activity regulates the polymerization of a partner MreB isoform essential for Spiroplasma swimming motility Takahashi, Daichi

301 8 p.
artikel
2 Aberrant activation of IL-6/JAK/STAT3/FOSL1 signaling induces renal abnormalities in a Xenopus model of Joubert syndrome-related disorders Uuganbayar, Udval

301 8 p.
artikel
3 Acetylation of microtubule-binding PinX1 orchestrates ribosome biogenesis to nutrient starvation via the RNA polymerase I preinitiation complex Lu, Gang

301 8 p.
artikel
4 Active site determinants of yeast Pah1 phosphatidate phosphatase activity and cellular functions Stukey, Geordan J.

301 8 p.
artikel
5 A dual role of fibroblast–epithelial crosstalk in acute and chronic lung injury Bammert, Marie-Therese

301 8 p.
artikel
6 A key loop in the catalytic pocket of the PL17 family of alginate lyases determines minimal substrate recognition Li, Xue

301 8 p.
artikel
7 A kinetic model of copper homeostasis in Saccharomyces cerevisiae Dulaney, Cade

301 8 p.
artikel
8 A molecular basis underpinning TRBV28+ T-cell receptor recognition of MR1–antigen Awad, Wael

301 8 p.
artikel
9 An anti-CD47 antibody binds to a distinct epitope in a novel metal ion-dependent manner to minimize cross-linking of red blood cells Lu, Xiao

301 8 p.
artikel
10 Antibacterial ADP-ribosyl cyclase toxins inhibit bacterial growth by rapidly depleting NAD(P)+ Colautti, Jake

301 8 p.
artikel
11 Application of NanoSIMS and isotopic labeling to analyze the spatial distribution of the plant iron chelator nicotianamine Nozoye, Tomoko

301 8 p.
artikel
12 Arylsulfatase B induces melanoma apoptosis by the ubiquitin ligase COP1 Bhattacharyya, Sumit

301 8 p.
artikel
13 A tubulin-binding protein that preferentially binds to GDP-tubulin and promotes GTP exchange Yon, Wesley J.

301 8 p.
artikel
14 Bioluminescence-based assays for quantifying endogenous protein interactions in live cells Niles, Andrew L.

301 8 p.
artikel
15 Cathepsin K as a key regulator of myocardial fibrosis in dilated cardiomyopathy and a promising therapeutic target Ma, Lanlan

301 8 p.
artikel
16 CH−π interactions confer orientational flexibility in protein–carbohydrate binding sites Keys, Allison M.

301 8 p.
artikel
17 Conformations of the three gates in Saccharomyces cerevisiae topoisomerase II and their response to DNA, nucleotide, and etoposide Stelljes, Jampa Tsedön

301 8 p.
artikel
18 Copper acquisition in Bacillus subtilis involves Cu(II) exchange between YcnI and YcnJ de Oliveira Silva, Yuri Rafael

301 8 p.
artikel
19 Cover
301 8 p.
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20 CryoEM structure of Rv2531c reveals cofactor-induced tetramer–dimer transition in a tuberculin amino acid decarboxylase Gupta, Jyoti

301 8 p.
artikel
21 Cu/Zn-superoxide dismutase naturally fused with a β-propeller lactonase in Deinococcus radiodurans Furukawa, Yoshiaki

301 8 p.
artikel
22 Development of novel mitochondrial pyruvate carrier inhibitors for breast cancer treatment Schumacher, Tanner J.

301 8 p.
artikel
23 Dimerization of Cdc13 is essential for dynamic DNA exchange on telomeric DNA Nickens, David G.

301 8 p.
artikel
24 Dynamic regulation of Sec24C by phosphorylation and O-GlcNAcylation during cell cycle progression Georgiou, George R.

301 8 p.
artikel
25 Engineered bacteriophytochrome heterodimers for research and applications Tuure, Iida

301 8 p.
artikel
26 Evidence against efficient spontaneous disassembly of prions into small oligomers Shoup, Daniel

301 8 p.
artikel
27 Exploring the regulatory mechanism of CCNA2 in colorectal cancer: Insights from multiomics and experimental analysis Lei, Xinyi

301 8 p.
artikel
28 Extensive citrullination of human serum albumin is physiological and not inherently immunogenic in rheumatoid arthritis Mustelin, Cecilia

301 8 p.
artikel
29 Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis Yammine, Kathryn M.

301 8 p.
artikel
30 First-in-class inhibitors of Nsp15 endoribonuclease of SARS-CoV-2: Modeling, synthesis, and enzymatic assay of thiazolidinedione and rhodanine analogs Mehyar, Nimer

301 8 p.
artikel
31 Functional analysis of amino acid substitutions within human AGT1 in a cell-based platform to support the diagnosis of primary hyperoxaluria type 1 Gatticchi, Leonardo

301 8 p.
artikel
32 Functional investigation of the RNA helicase MOV10 with respect to its interplay with factors involved in nonsense-mediated mRNA decay Xue, Guangpu

301 8 p.
artikel
33 GAPDH heme delivery to Indoleamine 2,3-dioxygenase 1 involves their complex formation and complementary charge pairing at the protein-protein interface Biswas, Pranjal

301 8 p.
artikel
34 Genetic variants linked to neurodevelopmental disorders within the β3-β4 loop of the TRIO PH2 domain release autoinhibition of GEF2 activity Carrizales, Melissa G.

301 8 p.
artikel
35 GoLoco/GPR motif-dependent regulation of Rap1GAP1 by Gαo is disrupted by Gαo encephalopathy variants Momplaisir, Nathalie L.

301 8 p.
artikel
36 Hemoglobin β-F41K: A recombinant oxygen carrier prototype engineered for enhanced heme retention, stability, and optimal oxygenation properties Khan, Mohd Asim

301 8 p.
artikel
37 Hsp110 nucleotide exchange factors may amplify Hsp70-disaggregation by enhanced entropic pulling Rebeaud, Mathieu E.

301 8 p.
artikel
38 Hypoxia-inducible factor 1α in Schwann cells promotes peripheral nerve myelination Kobayashi-Ujiie, Yuka

301 8 p.
artikel
39 Hypoxia promotes the generation of a versican-rich extracellular matrix by human coronary artery endothelial cells Jørgensen, Sara M.

301 8 p.
artikel
40 Identification of SRSF9 through pooled shRNA screening links BNIP3 splicing to autophagy and metabolic reprogramming in breast cancer Pandey, Anchala

301 8 p.
artikel
41 Improvement in the potency of a N1-methylpseudouridine-modified self-amplifying RNA through mutations in the RNA-dependent RNA polymerase Quintana, Verónica

301 8 p.
artikel
42 Inflamed endothelial cells express S1PR1 inhibitor CD69 to induce vascular leak Levesque, Michel V.

301 8 p.
artikel
43 Insights into the structural dynamics of the secretin family (class B1) G protein-coupled receptors Liu, Ting

301 8 p.
artikel
44 Interpreting ribosome dynamics during mRNA translation Uematsu, Saori

301 8 p.
artikel
45 Leber's hereditary optic neuropathy–associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis Yasheng, Meiheriayi

301 8 p.
artikel
46 Lipid asymmetry and membrane trafficking: Transbilayer distribution of structural phospholipids as regulators of exocytosis and endocytosis Caputo, Margherita

301 8 p.
artikel
47 Loss of integrin alpha7-mediated signaling induces a dendritic cell-like phenotype in macrophages cultured on laminin-211/221 isoforms Yoshiba, Nagako

301 8 p.
artikel
48 Low-mass zinc pools in Escherichia coli: Micromolar concentrations, diverse compositions, and Zn-glutathione dominating under Zn-replete conditions Kreinbrink, Alexia C.

301 8 p.
artikel
49 Maintenance of proper phosphatidylinositol-4-phosphate level by Stt4 and Sac1 contributes to vesicular transport to and from the plasma membrane Sano, Tomoki

301 8 p.
artikel
50 Microcurrent stimulation induces cell death in p53-mutant and 5-FU-resistant breast cancer Tanihara, Tomohito

301 8 p.
artikel
51 Modulation of the PTPRS proteoglycan switch by antibodies binding to the membrane-proximal fibronectin-type III domain Hein Da Rosa, Thales

301 8 p.
artikel
52 Molecular arrangements that accompany binding of rice xylanase inhibitor protein OsXIP and the Rhizopus oryzae GH11 xylanase RXyn2 Ohnuma, Takayuki

301 8 p.
artikel
53 Molecular basis for Gβγ-SNARE-mediated inhibition of synaptic vesicle fusion Eitel, Anna R.

301 8 p.
artikel
54 Molecular choreography of E1 enzymes in ubiquitin-like protein cascades: New insights into dynamics and specificity Stratton, Caleb M.

301 8 p.
artikel
55 Molecular determinants of nucleic acid recognition by an RNA-targeting ADP-ribosyltransferase toxin Lv, Fanyang

301 8 p.
artikel
56 Myeloid loss of scaffolding protein menin promotes liver fibrosis via H3K36me3 reprogramming Han, Qing

301 8 p.
artikel
57 Neuronal endolysosomal alterations induced by Apolipoprotein E4 emerge over time in primary neurons Nyberg, Emma

301 8 p.
artikel
58 NMR-guided identification of CYP11A1–Adrenodoxin interactions that differentially govern cholesterol and vitamin D3 metabolism McGlohon, Janie E.

301 8 p.
artikel
59 O-GlcNAcylation of fatty acid synthase is required for its proper subcellular localization, expression level, and activity Vanauberg, Dimitri

301 8 p.
artikel
60 PAXX/Ku interaction is rate limiting for repair of double-strand DNA breaks requiring end processing Gluza, Joanna

301 8 p.
artikel
61 PERK and IRE1α promote exosome secretion via blocking lysosomal degradation of multiple vesicular body Zhou, Shixin

301 8 p.
artikel
62 Phosphorylation-mediated regulation of the NADPH-dependent glutamate dehydrogenase, SpGdh1, from Schizosaccharomyces pombe Wang, Yi-Fan

301 8 p.
artikel
63 Polyamines stimulate the protein synthesis of the translation initiation factor eIF5A2, participating in mRNA decoding, distinct from eIF5A1 Suzuki, Masato

301 8 p.
artikel
64 Prediction of KIR3DL1 and human leukocyte antigen binding Maiers, Martin

301 8 p.
artikel
65 Proximity labeling techniques for protein–protein interaction mapping in plants Özmen, Beyza

301 8 p.
artikel
66 PTH stimulation of Rankl transcription is regulated by SIK2 and 3 and mediated by CRTC2 and 3 through action of protein phosphatases 1, 2, 4, and 5 Mosca, Michael J.

301 8 p.
artikel
67 Regulation of steady state ribosomal transcription in Mycobacterium tuberculosis: Intersection of sigma subunits, superhelicity, and transcription factors Ruiz Manzano, Ana

301 8 p.
artikel
68 Regulatory mechanism of the SenX3-RegX3 two-component system in Mycobacterium smegmatis: Roles of PhoU in sensing inorganic phosphate levels Seung, Youjin

301 8 p.
artikel
69 Repurposing clofazimine as an antibiotic to treat cholera: Identification of cellular and structural targets Yuan, Ming

301 8 p.
artikel
70 Restricted human CD45 isoglycoforms serve as functional E-selectin ligands and delineate hematopoietic maturity Ales, Evan

301 8 p.
artikel
71 Sal is a proteobacterial bile acid aldolase that repurposes key thiolase catalytic residues for retroaldol cleavage of C5 steroid side chains Rolfe, Nicolas

301 8 p.
artikel
72 Secretory autophagy mediates lysosomal and autophagic degradation for α-synuclein proteostasis Sawai, Taiki

301 8 p.
artikel
73 Silencing PIM1 inhibits ENO1-induced AKT activation and attenuates fibrillogenesis during spinal cord injury-induced skeletal muscle atrophy Yu, Xiao

301 8 p.
artikel
74 Spatiotemporal fluctuations in fluorescence intensity of rhodamine phalloidin–labeled actin filaments Toshino, Kenta

301 8 p.
artikel
75 Stressful situations: Molecular insights on mitochondrial quality control pathways Romanelli, Sabrina

301 8 p.
artikel
76 Structural and functional characterization of CREB-binding protein (CREBBP) as a histone propionyltransferase Cui, Guiling

301 8 p.
artikel
77 Structural biology of Parkinson’s disease-associated leucine-rich repeat kinase 2 (LRRK2) Leschziner, Andres E.

301 8 p.
artikel
78 Subcellular determinants of orthoflavivirus protease activity Corliss, Lochlain

301 8 p.
artikel
79 Synergy between RNA editing and alternative splicing modulates the biological properties of the voltage-gated calcium channel CaV1.3 Munyao, Willy

301 8 p.
artikel
80 Systematic characterization of zinc in a series of breast cancer cell lines reveals significant changes in zinc homeostasis Woyciehowsky, Mena

301 8 p.
artikel
81 Targeted degradation of α-synuclein by arginine-based PROTACs Shen, Linjing

301 8 p.
artikel
82 Targeting HIF-P4H-2 in APP/PS1 Alzheimer’s mouse model improves glucose metabolism, reduces dystrophic neuritis, and maintains exploratory activity Kurkela, Margareta

301 8 p.
artikel
83 TCR activation stimulates regulated intramembrane proteolysis of L-selectin by presenilin 1 and localized proteasomal degradation of the cytoplasmic tail Moon, Owen R.

301 8 p.
artikel
84 TFAP2C drives cisplatin resistance in bladder cancer by upregulating YAP and activating β-catenin signaling Pan, Qiufeng

301 8 p.
artikel
85 The ability of SAMHD1-deficient monocytes to trigger the Type I IFN response depends on cGAS and mitochondrial DNA Rabinowitz, Jesse

301 8 p.
artikel
86 The critical roles of bioactive sphingolipids in inflammation Gomez-Larrauri, Ana

301 8 p.
artikel
87 The Escherichia coli RelB antitoxin C terminus is essential for RelE toxin suppression and transcriptional repression Tanquary, Julia

301 8 p.
artikel
88 The GTPase κB-Ras is an essential subunit of the RalGAP tumor suppressor complex Rasche, René

301 8 p.
artikel
89 The impact of RNA chemical probing reagents on RNA-binding proteins Klingler, David

301 8 p.
artikel
90 The kinesin-14 family motor protein KIFC2 promotes prostate cancer progression by regulating p65 Liu, Xinyu

301 8 p.
artikel
91 The metastasis-associated protein MTA3 promotes cardiac repair by inhibiting the fibroblast to myofibroblast transition during fibrosis Wang, Xu

301 8 p.
artikel
92 The poly(A) polymerase Star-PAP is regulated by stably associated phosphoinositide messengers Wen, Tianmu

301 8 p.
artikel
93 The redox landscape of pyruvate:ferredoxin oxidoreductases reveals often conserved Fe–S cluster potentials Bonitatibus, Sheila C.

301 8 p.
artikel
94 The role of chromatin in retroviral preintegration complex function Sapp, Nicklas

301 8 p.
artikel
95 The structural characteristics of cellular phospholipid acyl chains required for ABCA1-mediated HDL formation Nagao, Kohjiro

301 8 p.
artikel
96 The ubiquitin ligase Triad1 influences myeloid leukemogenesis by regulating the integrated stress response Wang, Hao

301 8 p.
artikel
97 Transcriptional responses to nitric oxide are widescale and source-dependent Schindler, Joseph C.

301 8 p.
artikel
98 Translation-independent association of mRNAs that encode protomers of the 5-HT2A-mGlu2 receptor complex Saha, Somdatta

301 8 p.
artikel
99 Two stages of substrate discrimination dictate selectivity in the Escherichia coli MetNI-Q ABC transporter system Yang, Janet G.

301 8 p.
artikel
100 Ultrasensitive bioluminescent reporters of protein kinase A based on luciferase activity modulated by phosphorylation (PKA LAMP) Kong, Yufang

301 8 p.
artikel
101 Understanding the substrate recognition and catalytic mechanism of 2-O-methyl fucosidases from glycoside hydrolase family 139 McIver, Zak

301 8 p.
artikel
102 Vacuole protein sorting 18 (Vps18) suppresses epithelial growth factor receptor (EGFR) expression and lung tumorigenesis Dai, Wuhou

301 8 p.
artikel
103 Zinc oxide nanoparticles disrupt peroxisome-endoplasmic reticulum contacts and increase very-long-chain fatty acid content Zhong, Juncheng

301 8 p.
artikel
                             103 gevonden resultaten
 
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