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                             124 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A 36-base hairpin within lncRNA DRAIC, which is modulated by alternative splicing, interacts with the IKKα coiled-coil domain and inhibits NF-κB and tumor cell phenotypes Hao, Xiaoxiao

301 6 p.
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2 ABHD18 degrades cardiolipin by stepwise hydrolysis of fatty acids Ren, Mindong

301 6 p.
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3 Acid sphingomyelinase recruits palmitoylated CD36 to membrane rafts and enhances lipid uptake Ding, Meng

301 6 p.
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4 A cobalamin-dependent pathway of choline demethylation from the human gut acetogen Eubacterium limosum Jiang, Ruisheng

301 6 p.
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5 Aggrecan immobilizes to perineuronal nets through hyaluronan-dependent and hyaluronan-independent binding activities Otsuka, Matthew Y.

301 6 p.
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6 A high-throughput compatible workflow for the biochemical identification and characterization of molecular glues Guilbert, Ryan

301 6 p.
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7 Alisertib impairs the stemness of hepatocellular carcinoma by inhibiting purine synthesis Qi, Zhuoran

301 6 p.
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8 All intrinsically active Erk1/2 mutants autophosphorylate threonine207/188, a plausible regulator of the TEY motif phosphorylation Baskin, Alexey

301 6 p.
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9 Allosteric communication mechanism in the glucagon receptor van der Velden, Wijnand J.C.

301 6 p.
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10 Allosteric factors in the calcium/calmodulin-responsive kinase II hub domain determine selectivity of GHB ligands for CaMKIIα Gauger, Stine J.

301 6 p.
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11 Altering the ligand specificity of DectiSomes Ambati, Suresh

301 6 p.
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12 Alternative splicing categorizes organ development by stage and reveals unique human splicing variants linked to neuromuscular disorders Li, Chen

301 6 p.
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13 A new age in structural S-layer biology: Experimental and in silico milestones Grill-Walcher, Stephanie

301 6 p.
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14 Antioxidant capacity of the iron–sulfur cluster assembly protein IscU2 is mediated by aspartate metabolism to promote tumor survival Yang, Xunjun

301 6 p.
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15 An uncharacterized gene from the Actinobacillus genus encodes a glucosyltransferase with successive transfer activity and unique substrate specificity Yamasaki, Takahiro

301 6 p.
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16 ARV1 is a component of the enzyme initiating glycosylphosphatidylinositol biosynthesis Lu, TianTian

301 6 p.
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17 A strategy for liver selective NRF2 induction via cytochrome P450-activated prodrugs with low activity in hypoxia Ng, Mei Ying

301 6 p.
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18 A SUMO-interacting motif in the guanine nucleotide exchange factor EPAC1 is required for subcellular targeting and function Yang, Wenli

301 6 p.
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19 A TATA-box-binding protein binds single-stranded DNA in two modes: To poly(G) tracts and to flexible DNA regions Freitag, Kieran

301 6 p.
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20 A tumor necrosis factor-α–responsive cryptic promoter drives overexpression of the human endogenous retrovirus ERVK-7 Lee, Sojung

301 6 p.
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21 Bile acids inhibit equilibrative adenosine transport to alter adenosine receptor signaling in cholestasis Joshi, Arnav

301 6 p.
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22 Biochemical impact of p300-mediated acetylation of replication protein A: Implications for DNA metabolic pathway choice Ononye, Onyekachi

301 6 p.
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23 Blockade of the estrogen receptor alpha–pregnane X receptor axis protects ovariectomized mice against ethanol-induced hepatotoxicity Twum, Elizabeth

301 6 p.
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24 CaV3.3 T-type calcium channels contribute to carboplatin resistance in retinoblastoma Kim, Sooyun

301 6 p.
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25 Cellular crosstalk in fibrosis: Insights into macrophage and fibroblast dynamics Froom, Zachary S.C.S.

301 6 p.
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26 Challenging activity and signaling bias in tachykinin NK1 and NK2 receptors by truncated neuropeptides Petersen, Jacob E.

301 6 p.
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27 Characterization of a two-component kinase that initiates the bacterial catabolism of hydroxyphenylethanones Dexter, Gara N.

301 6 p.
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28 Circadian clock-independent ultradian rhythms in lipid metabolism in the Drosophila fat body Lago Solis, Blanca

301 6 p.
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29 CMP-sialic acid synthetase in Drosophila requires N-glycosylation of a noncanonical site Novikov, Boris

301 6 p.
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30 Conditional lethality and suppressor analysis of plasmid-based temperature-sensitive fabZ expression in Pseudomonas aeruginosa Chen, Zhenhua

301 6 p.
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31 Connecting the dots: Epigenetic regulation of extrachromosomal and inherited DNA amplifications Azadegan, Chloe

301 6 p.
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32 Constitutively active Arabidopsis cryptochrome 2 alleles identified using yeast selection and deep mutational scanning Taslimi, Amir

301 6 p.
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33 Cooperative inhibition in cytochrome P450 between a substrate and an apparent noncompetitive inhibitor Hirano, Yu

301 6 p.
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34 Covalent binding of thioredoxin to TXNIP is required for diet-induced insulin resistance in the liver Dagdeviren, Sezin

301 6 p.
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35 Cover
301 6 p.
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36 CpX Hunter web tool allows high-throughput identification of CpG, CpA, CpT, and CpC islands: A case study in Drosophila genome Bartas, Martin

301 6 p.
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37 CRAC channel activity pulsates during cytosolic Ca2+ oscillations Lin, Yu-Ping

301 6 p.
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38 CRISPRi screen uncovers lncRNA regulators of human monocyte growth Flores-Arenas, Cristina

301 6 p.
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39 Crystal structure and mutagenesis of a nucleic acid–binding BRCT domain in human PARP4 Frigon, Léonie

301 6 p.
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40 Damage-associated molecular patterns (DAMPs) in vascular diseases Antonello, Jacob

301 6 p.
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41 Delayed inactivation of TRPC6 as a determinative characteristic of FSGS-associated variants Okada, Ryo

301 6 p.
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42 Derivation of human trophoblast stem cells from placentas at birth Karakis, Victoria

301 6 p.
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43 Directed evolution of metalloproteinase inhibitor TIMP-1 for selective inhibition of MMP-9 exploits catalytic and fibronectin domain interactions Shoari, Alireza

301 6 p.
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44 Discovery and biochemical characterization of the D-aspartyl endopeptidase activity of the serine protease LACTB Ito, Genta

301 6 p.
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45 DNA stimulates the deacetylase SIRT6 to mono-ADP-ribosylate proteins with histidine repeats Pederson, Nicholas J.

301 6 p.
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46 Ebola virus nucleoprotein interaction with host protein phosphatase-1 regulates its dimerization and capsid formation Ahmad, Asrar

301 6 p.
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47 Elevated mevalonolactone from Ruminococcus torques contributes to metabolically unhealthy obesity development Nie, Hong-Yu

301 6 p.
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48 EML2 and EML4 splice variants regulate microtubule remodeling during neuronal cell differentiation Marasi, Venus

301 6 p.
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49 Endocytosis of sialic acid Neu5Gc and elevated p53 contributes to preimplantation embryonic arrest during in vitro fertilization Yuan, Xin

301 6 p.
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50 Engineering an antimicrobial chimeric endolysin that targets the phytopathogen Pseudomonas syringae pv. actinidiae Warring, Suzanne L.

301 6 p.
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51 Evidence of bidirectional transmembrane signaling by the sensor histidine kinase GacS from Pseudomonas aeruginosa Salar, Safoura

301 6 p.
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52 Exploiting FcRn engagement of an albumin-CpG oligonucleotide covalent conjugate for potent TLR9 immune induction Pilati, Diego

301 6 p.
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53 Extent of N-glycosylation of the metalloproteinase inhibitor and cytokine TIMP-1 determines pancreatic cancer cell proliferation and survival via CD63 Häußler, Daniel

301 6 p.
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54 Fatty acyl-CoA reductase FAR1 is essential for the testicular seminolipid synthesis required for spermatogenesis and male fertility Tamazawa, Ayano

301 6 p.
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55 Fluorescent labeling of proteins in vitro and in vivo using encoded peptide tags de Luis, Maya

301 6 p.
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56 Guard cell and whole plant expression of AtTOR improves performance under drought and enhances water use efficiency Liu, Li

301 6 p.
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57 Hepatic ChREBP reciprocally modulates systemic insulin sensitivity in NAFLD Sen, Aniket

301 6 p.
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58 Hepatic glutamic-oxaloacetic transaminase promotes mitochondrial respiration energized at complex II and alters whole body metabolism Fink, Brian D.

301 6 p.
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59 High-frequency transcription leads to rapid R-loop formation Palmer, Bradleigh

301 6 p.
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60 High uric acid exacerbates nonalcoholic steatohepatitis through NLRP3 inflammasome and gasdermin D-mediated pyroptosis Xu, Zixin

301 6 p.
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61 Identification and design principles of far-red–absorbing chlorophyll in the light-harvesting complex Saito, Keisuke

301 6 p.
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62 Identification of UDP-dependent glycosyltransferases in the wallflower cardenolide biosynthesis pathway Patrick, Owen S.

301 6 p.
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63 Impact of an oxidative RNA lesion on in vitro replication catalyzed by SARS-CoV-2 RNA-dependent RNA polymerase Akagawa, Masataka

301 6 p.
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64 Inactivation of SIAH-1 E3 ligase attenuates Aβ toxicity by suppressing ubiquitin-dependent DVE-1 degradation in Caenorhabditis elegans models of Alzheimer’s disease Sun, Lihua

301 6 p.
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65 In situ detection of activation of CAPN3, a responsible gene product for LGMDR1, in mouse skeletal myotubes Hisatsune, Chihiro

301 6 p.
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66 In vitro sulfuration of Rhodobacter capsulatus formate dehydrogenase Duffus, Benjamin R.

301 6 p.
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67 Key amino acids in RNA polymerase and helicase proteins regulate RNA synthesis efficiency in porcine reproductive and respiratory syndrome virus Li, Hui

301 6 p.
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68 Live cell analysis of mobility and decay kinetics of the histone variant H3.3 Nehru, Vishal

301 6 p.
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69 LncRNA-induced lysosomal localization of NHE1 promotes increased lysosomal pH in macrophages leading to atherosclerosis Shi, Pengcheng

301 6 p.
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70 Loss of SLX4IP leads to common fragile site instability and compromises DNA interstrand crosslink repair in vivo Ingham, Andreas

301 6 p.
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71 Mechanism and kinetics of turnover inhibitors of nicotinamide N-methyl transferase in vitro and in vivo Akerud, Tomas

301 6 p.
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72 Microbial metabolite ammonia disrupts TGF-β signaling to promote colon cancer Bhowmick, Krishanu

301 6 p.
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73 Microglial TAK1 promotes neurotoxic astrocytes and cognitive impairment in LPS-induced hippocampal neuroinflammation Han, Xiao

301 6 p.
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74 MitoSNO inhibits mitochondrial hydrogen peroxide generation by α-ketoglutarate dehydrogenase Chalifoux, Olivia

301 6 p.
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75 Molecular basis for differential PIP2-mediated association between vinculin and its splice isoform metavinculin Khan, Mohammad Ashhar I.

301 6 p.
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76 Molecular glue binding behavior of phosphoantigens to alpaca butyrophilins Liu, Chang

301 6 p.
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77 MYC controls STING levels to downregulate inflammatory signaling in breast cancer cells upon DNA damage Linstra, Renske

301 6 p.
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78 N-acetyltransferase 10 promotes glioblastoma malignancy via mRNA stabilization of jumonji and AT-rich interaction domain containing 2 Inoki, Takuto

301 6 p.
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79 Nick sealing of polβ mismatch insertion products by LIG1 and LIG3α during 8-oxoG bypass leads to mutagenic or error-free base excision repair Lee, Kar Men

301 6 p.
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80 NOTCH2 disrupts the synovial fibroblast identity and the inflammatory response of epiphyseal chondrocytes Canalis, Ernesto

301 6 p.
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81 Nrf2-and p53-inducible REDD2/DDiT4L/Rtp801L confers pancreatic β-cell dysfunction, leading to glucose intolerance in high-fat diet-fed mice Yamada, Yukiho

301 6 p.
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82 Nuclear protein FNBP4: A novel inhibitor of non-diaphanous formin FMN1-mediated actin cytoskeleton dynamics Das, Shubham

301 6 p.
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83 NUDT16 enhances the resistance of cancer cells to DNA-damaging agents by regulating replication fork stability via reversing HMGA1 ADP-ribosylation Zhou, Yingshi

301 6 p.
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84 Optimization of the PROTAC linker region of the proteasome substrate receptor hRpn13 rationalized by structural modeling with molecular dynamics Lu, Xiuxiu

301 6 p.
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85 Parkin mediates the mitochondrial dysfunction through mRpL18 Ti, Xiuxiu

301 6 p.
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86 Phase separation as a key mechanism in plant development, environmental adaptation, and abiotic stress response Pougy, Karina C.

301 6 p.
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87 Phosphorylation modulates secondary structure of intrinsically disorder regions in RNA polymerase II Chen, Wei

301 6 p.
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88 Phosphorylation of SNX17 impedes activation of Retriever-mediated sorting Speidel, Jan Dominik

301 6 p.
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89 Potent activity of prostaglandin J2 on prostanoid DP receptors Senoo, Kanaho

301 6 p.
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90 ProOvErlap: Assessing feature proximity/overlap and testing statistical significance from genomic intervals Gualandi, Nicolò

301 6 p.
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91 Quantification and structure–function analysis of calpain-1 and calpain-2 protease subunit interactions Shapovalov, Ivan

301 6 p.
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92 Quantifying small GTPase activation status using a novel fluorescence HPLC-based assay Araki, Makoto

301 6 p.
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93 Recently discovered heteromeric enzymes in natural product biosynthesis Yu, Zhongtian

301 6 p.
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94 Redox response feature and mechanism of Arf1 and their implications for those of Ras and Rho GTPases Johnson, Hope Elizabeth

301 6 p.
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95 RIPC improves myocardial injury by promoting mitochondrial protection via the PGC-1α/Nrf2 pathway Zhao, Zhenzhou

301 6 p.
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96 SART1 uniquely localizes to spindle poles forming a SART1 cap and promotes spindle pole assembly Yokoyama, Hideki

301 6 p.
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97 Selective inhibition of TRPV3 channel by natural rosmarinic acid and its analogs for alleviation of skin lesions through downregulation of NF-κB pathway Qu, Yaxuan

301 6 p.
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98 Seo1p, a high-affinity, plasma membrane transporter of the γ-Glu-met dipeptide in yeasts and fungi Dubey, Pratiksha

301 6 p.
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99 Setdb1 and Atf7IP form a hetero-trimeric complex that blocks Setdb1 nuclear export Kariapper, Leena S.

301 6 p.
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100 Smooth muscle Cxcl12 contributions to vascular remodeling in flow and hypoxia-induced pulmonary hypertension Klouda, Timothy

301 6 p.
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101 Specific phosphoinositide interaction of Jps1 is a key feature during unconventional secretion in Ustilago maydis Dali, Sanchi

301 6 p.
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102 Structural and functional insights into the substrate specificity of the pseudouridine monophosphate phosphatase HDHD1A Seo, Suyoung

301 6 p.
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103 Structure and catalytic mechanism of methylisocitrate lyase, a potential drug target against Coxiella burnetii Stuart, William S.

301 6 p.
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104 Structure of the phosphocysteine intermediate of the phosphatase of regenerating liver PTP4A1 Mahbub, Luba

301 6 p.
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105 Symmetric stimulation of Hsp90 catalyzed ATP hydrolysis through enhanced active site gate dynamics Magnan, Breanna

301 6 p.
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106 Tamoxifen induces protection against manganese toxicity by REST upregulation via the ER-α/Wnt/β-catenin pathway in neuronal cells Digman, Alexis

301 6 p.
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107 The bacterial chaperone CsgC inhibits functional amyloid CsgA formation by promoting the intrinsically disordered pre-nuclear state Balistreri, Anthony

301 6 p.
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108 The impact of subunit type, alternative splicing, and auxiliary proteins on AMPA receptor trafficking Couch, Tyler

301 6 p.
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109 The late-stage steps of Burkholderia cenocepacia protein O-linked glycan biosynthesis are conditionally essential Jebeli, Leila

301 6 p.
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110 The LDL receptor-related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions Wani, Mashhood M.

301 6 p.
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111 The macrophage sterol transport protein ORP2 promotes cholesterol efflux and prevents foam cell formation and atherosclerosis Wang, Xiaowei

301 6 p.
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112 The mechanism of peptidoglycan O-acetylation in Gram-negative bacteria typifies bacterial MBOAT-SGNH acyltransferases Anderson, Alexander C.

301 6 p.
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113 The neural stem cell gene PAFAH1B1 controls cell cycle progression, DNA integrity, and paclitaxel sensitivity of triple-negative breast cancer cells Majmudar, Parth R.

301 6 p.
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114 The nucleocapsid protein of Crimean–Congo hemorrhagic fever virus interacts with eIF4A to promote the translation of viral mRNA in cells Ali, Saima

301 6 p.
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115 The ribonuclease RNase T2 mediates selective autophagy of ribosomes induced by starvation in Saccharomyces cerevisiae Minami, Atsushi

301 6 p.
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116 The role of human Shu complex in ATP-dependent regulation of RAD51 filaments during homologous recombination–associated DNA damage response Chu, Sam S.H.

301 6 p.
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117 The transcriptional regulator Sin3a activates CD44 and promotes collective luminal breast cancer cell migration Qiu, Yaqi

301 6 p.
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118 The ubiquitin ligase NKLAM promotes apoptosis and suppression of cell growth Willard, Paul A.

301 6 p.
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119 The VanS sensor histidine kinase from type-B vancomycin-resistant enterococci recognizes vancomycin directly Maciunas, Lina J.

301 6 p.
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120 Throwing a spotlight on genomic dark matter: The power and potential of transposon-insertion sequencing Nolan, Laura M.

301 6 p.
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121 TOX High-Mobility Group Box Family Member 4 promotes DNA double-strand break repair via nonhomologous end joining Wang, Feifei

301 6 p.
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122 UCHL1 regulates adiponectin receptors in Sertoli cells to maintain testicular homeostatic balance Yang, Donghui

301 6 p.
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123 Variations in kinase and effector signaling logic in a bacterial two component signaling network Swingle, Danielle

301 6 p.
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124 WWP1 mediates the ubiquitination and degradation of HIPK3 in bladder cancer cells Chen, Haichao

301 6 p.
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                             124 gevonden resultaten
 
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