Digitale Bibliotheek
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                             100 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A combination of alveolar type 2–specific p38α activation with a high-fat diet increases inflammatory markers in mouse lungs Heng, C.K. Matthew

301 4 p.
artikel
2 A conserved phosphorylation mechanism for regulating the interaction between the CMG replicative helicase and its forked DNA substrate Koit, Sandra

301 4 p.
artikel
3 A high-throughput assay platform to discover small molecule activators of the phospholipase PLC-γ2 to treat Alzheimer's disease Carr, Adam J.

301 4 p.
artikel
4 An alternative adaptation strategy of the CCA-adding enzyme to accept noncanonical tRNA substrates in Ascaris suum Thalhofer, Valerie

301 4 p.
artikel
5 Androgen receptor–induced lncRNA SOX2-OT promotes triple-negative breast cancer tumorigenesis via targeting miR-320a-5p–CCR5 axis Hu, Yixuan

301 4 p.
artikel
6 A novel spider toxin as a selective antagonist of the Kv1 subfamily of voltage-gated potassium channels through gating modulation Xiao, Zhen

301 4 p.
artikel
7 Antimicrobial peptides selectively target malaria parasites by a cholesterol-dependent mechanism Kiper, Edo

301 4 p.
artikel
8 Antioxidant-independent activities of alpha-tocopherol Chen, Matthew

301 4 p.
artikel
9 A p.N92K variant of the GTPase RAC3 disrupts cortical neuron migration and axon elongation Sugawara, Ryota

301 4 p.
artikel
10 ATP synthesis of Enterococcus hirae V-ATPase driven by sodium motive force Otomo, Akihiro

301 4 p.
artikel
11 BANCR-containing extracellular vesicles enhance breast cancer resistance Song, Xinming

301 4 p.
artikel
12 Binding mode between peptidyl-tRNA hydrolase and the peptidyl-A76 moiety of the substrate Uehara, Yuji

301 4 p.
artikel
13 Cancer hotspot mutations rewire ERK2 specificity by selective exclusion of docking interactions Torres Robles, Jaylissa

301 4 p.
artikel
14 Carbohydrate deacetylase, a key enzyme in oxidative chitin degradation, is evolutionarily linked to amino acid deacetylase Wang, Jing-Ping

301 4 p.
artikel
15 Cardioprotective effect of genetic ablation of the G-protein-coupled receptor kinase GRK2 in adult pancreatic β-cells during high-fat diet Snyder, Jonathan

301 4 p.
artikel
16 Cargo adaptor identity controls the mechanism and kinetics of dynein activation Gillies, John P.

301 4 p.
artikel
17 CCCTC-binding factor N-terminal domain regulates clustered protocadherin gene expression by enhancing cohesin processivity Zhang, Yijun

301 4 p.
artikel
18 Characterization of a rhodopsin-phosphodiesterase from Choanoeca flexa to be combined with rhodopsin-cyclases for bidirectional optogenetic cGMP control Liem, Nicolas

301 4 p.
artikel
19 Characterization of quinazolinone calcilytic therapy for autosomal dominant hypocalcemia type 1 (ADH1) Hannan, Fadil M.

301 4 p.
artikel
20 Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine Hernandez, Genaro

301 4 p.
artikel
21 Cover
301 4 p.
artikel
22 Cryo-EM structure of apo-form human DNA polymerase δ elucidates its minimal DNA synthesis activity without PCNA Shin, Yeonoh

301 4 p.
artikel
23 Cryo-EM structures define the electron bifurcating flavobicluster and ferredoxin binding site in an archaeal Nfn-Bfu transhydrogenase Xiao, Xiansha

301 4 p.
artikel
24 Declining activity of serum response factor in aging aorta in relation to aneurysm progression Rippe, Catarina

301 4 p.
artikel
25 Dentin sialoprotein promotes endothelial differentiation of dental pulp stem cells through DSPaa34–50–endoglin–AKT1 axis Xu, Ximin

301 4 p.
artikel
26 Differential association of EphA2 intracellular regions in biased signaling Zapata-Mercado, Elmer

301 4 p.
artikel
27 Dioxygenation of tryptophan residues by superoxide and myeloperoxidase Dickerhof, Nina

301 4 p.
artikel
28 Direct observation of importin α family member KPNA1 in axonal transport with or without a schizophrenia-related mutation Mizuno, Katsutoshi

301 4 p.
artikel
29 Dissecting the mechanism of NOP56 GGCCUG repeat-associated non-AUG translation using cell-free translation systems Hasumi, Mayuka

301 4 p.
artikel
30 Distinct neuronal vulnerability and metabolic dysfunctions are characteristic features of fast-progressing Alzheimer's patients with Lewy bodies Rahman, Mohammed Waseequr

301 4 p.
artikel
31 Double prenylation of budding yeast Ykt6 regulates cell wall integrity and autophagy Tateishi, Masaki

301 4 p.
artikel
32 Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity in cells Pires, Maria J.

301 4 p.
artikel
33 Dynamic interactions of dimeric hub proteins underlie their diverse functions and structures: A comparative analysis of 14-3-3 and LC8 Howe, Jesse

301 4 p.
artikel
34 Dynein light chains 1 and 2 are auxiliary proteins of pH-sensitive Kir4.1 channels Lee, Sun-Joo

301 4 p.
artikel
35 eIF3d and eIF4G2 mediate an alternative mechanism of cap-dependent but eIF4E-independent translation initiation Quartey, Jacob N.K.

301 4 p.
artikel
36 Emerging concepts in the molecular cell biology and functions of mammalian erythrocytes Kumar, Sangeetha Devi

301 4 p.
artikel
37 Enhanced identification of small molecules binding to hnRNPA1 via cryptic pockets mapping coupled with X-ray fragment screening Dunnett, Louise

301 4 p.
artikel
38 Epitomic profiling and functional characteristics of pemphigus vulgaris autoantibody binding to keratinocyte M3 muscarinic acetylcholine receptor Reyes-Ruiz, Jorge Mauricio

301 4 p.
artikel
39 ER stress and viral defense: Advances and future perspectives on plant unfolded protein response in pathogenesis Adhikari, Binita

301 4 p.
artikel
40 Glutamate decarboxylase confers acid tolerance and enhances survival of mycobacteria within macrophages Rai, Rupal

301 4 p.
artikel
41 Gonadotropin-releasing hormone regulates transcription of the inhibin B co-receptor, TGFBR3L, via early growth response one Lin, Yeu-Farn

301 4 p.
artikel
42 G protein–coupled estrogen receptor deficiency exacerbates demyelination through microglial ferroptosis Mi, Xiaojuan

301 4 p.
artikel
43 Human glutathione transferases catalyze the reaction between glutathione and nitrooleic acid Steglich, Martina

301 4 p.
artikel
44 Human tau promotes Warburg effect–like glycolytic metabolism under acute hyperglycemia conditions Yao, Jinyi

301 4 p.
artikel
45 Immune checkpoint protein PD-L1 promotes transcription of angiogenic and oncogenic proteins IL-8, Bcl3, and STAT1 in ovarian cancer cells Reddy, Suprataptha U.

301 4 p.
artikel
46 Inefficient maturation of disease-linked mutant forms of the KCC2 potassium-chloride cotransporter correlates with predicted pathogenicity Kok, Morgan

301 4 p.
artikel
47 Insights into the transcriptional regulation of CD22 in B cell chronic lymphocytic leukemia Enkhbayar, Bayarmaa

301 4 p.
artikel
48 Interaction between CaV2.1 and Junctophilin3/4 depends on the II-III loop of CaV2.1 and on the α-helical region of Junctophilin3/4 Perni, Stefano

301 4 p.
artikel
49 In vitro characterization of the yeast DEAH/RHA RNA helicase Dhr1 Lin, Ran

301 4 p.
artikel
50 In vitro inhibition of voltage-dependent sodium currents by the antifungal drug amorolfine Ghovanloo, Mohammad-Reza

301 4 p.
artikel
51 In vitro reconstitution reveals substrate selectivity of protein S-acyltransferases Mondal, Tanmay

301 4 p.
artikel
52 Mechanistic insights into proton-coupled substrate translocation of nucleoside proton symporters Xiao, Qingjie

301 4 p.
artikel
53 Methionine cycle inhibition disrupts antioxidant metabolism and reduces glioblastoma cell survival Rowland, Emma C.

301 4 p.
artikel
54 Microvillus inclusion disease-causing MYO5B point mutations exert differential effects on motor function Bowman, Deanna M.

301 4 p.
artikel
55 Mitochondrial glutaredoxin Grx5 functions as a central hub for cellular iron-sulfur cluster assembly Pandey, Ashutosh K.

301 4 p.
artikel
56 Molecular dissection of tendon development and healing: Insights into tenogenic phenotypes and functions Sakai, Takao

301 4 p.
artikel
57 Mutant protein chemical rescue: From mechanisms to therapeutics O'Meara, Timothy R.

301 4 p.
artikel
58 New routes for spermine biosynthesis Li, Bin

301 4 p.
artikel
59 Not all 5′-deoxyadenosines are created equal: Tracing the provenance of 5′-deoxyadenosine formed by the radical S-adenosyl-L-methionine enzyme 7-carboxy-7-deazaguanine synthase Nayak, Saswata

301 4 p.
artikel
60 O-GlcNAcylation modification of MyoD regulates skeletal muscle fiber differentiation by antagonizing the UPF1 pathway Kou, Lele

301 4 p.
artikel
61 Optogenetic tools for inducing organelle membrane rupture Nagashima, Yuto

301 4 p.
artikel
62 Ovarian tachykinin signaling system induces the growth of secondary follicles during the gonadotropin-independent process Kawada, Tsuyoshi

301 4 p.
artikel
63 Pak1 dysregulates pyruvate metabolism in PDAC cells by exerting a phosphorylation-mediated regulatory effect on PDHA1 Murugan, Sowmiya

301 4 p.
artikel
64 PKM splice-switching ASOs induce upregulation of dual-specificity phosphatases and dephosphorylation of ERK1/2 in hepatocellular carcinoma Voss, Dillon M.

301 4 p.
artikel
65 Polarization-independent regulation of the subcellular localization of Yes-associated protein 1 during preimplantation development Saito, Shun

301 4 p.
artikel
66 Profiling the regulatory landscape of sialylation through miRNA targeting of CMP- sialic acid synthetase Jame-Chenarboo, Faezeh

301 4 p.
artikel
67 Proximal cysteine residues in proteins promote N ε-carboxyalkylation of lysine residues by α-dicarbonyl compounds Panja, Sudipta

301 4 p.
artikel
68 Pseudomonas aeruginosa PfpI is a methylglyoxalase Grimm, Larson

301 4 p.
artikel
69 Pyruvate dehydrogenase kinase 1 controls triacylglycerol hydrolysis in cardiomyocytes Atser, Michael G.

301 4 p.
artikel
70 Rational design, synthesis, and evaluation of novel polypharmacological compounds targeting NaV1.5, KV1.5, and K2P channels for atrial fibrillation Camargo-Ayala, Lorena

301 4 p.
artikel
71 Requirements for nuclear GRP78 transcriptional regulatory activities and interaction with nuclear GRP94 Liu, Ze

301 4 p.
artikel
72 Resveratrol reduces RVLM neuron activity via activating the AMPK/Sirt3 pathway in stress-induced hypertension Wang, Lin-Ping

301 4 p.
artikel
73 Roles of basic amino acid residues in substrate binding and transport of the light-driven anion pump Synechocystis halorhodopsin (SyHR) Nakama, Masaki

301 4 p.
artikel
74 Spermine attenuates TGF-β-induced EMT by downregulating fibronectin Liu, Huidong

301 4 p.
artikel
75 Spiroplasma eriocheiris FtsZ assembles the ring-like structure assisted by SepF Kasai, Taishi

301 4 p.
artikel
76 Steroid receptors and coregulators: Dissemination of sex differences and emerging technologies Pauss, Sally N.

301 4 p.
artikel
77 ST3GAL1 regulates cancer cell migration through crosstalk between EGFR and neuropilin-1 signaling Fan, Tan-chi

301 4 p.
artikel
78 Stress-induced changes in endogenous TP53 mRNA 5′ regulatory region Kim, Jin Yeong

301 4 p.
artikel
79 Structural analyses of apolipoprotein A-IV polymorphisms Q360H and T347S elucidate the inhibitory effect against thrombosis Shoara, Aron A.

301 4 p.
artikel
80 Structural and functional characterization of the extended-diKH domain from the antiviral endoribonuclease KHNYN Youle, Rebecca L.

301 4 p.
artikel
81 Structural basis of a distinct α-synuclein strain that promotes tau inclusion in neurons Sun, Chuanqi

301 4 p.
artikel
82 Structural insight into the catalytic mechanism of the bifunctional enzyme l-fucokinase/GDP-fucose pyrophosphorylase Lin, Sheng-Wei

301 4 p.
artikel
83 Structure-function studies of a nucleoplasmin isoform from Plasmodium falciparum Saharan, Ketul

301 4 p.
artikel
84 Substrate recognition and cleavage-site preferences of Lon protease Cragan, Melanie

301 4 p.
artikel
85 Substrate recognition in Bacillus anthracis sortase B beyond its canonical pentapeptide binding motif and use in sortase-mediated ligation Jackson, Sophie N.

301 4 p.
artikel
86 Substrate-specific effects point to the important role of Y361 as part of the YER motif in closing the binding pocket of OCT1 Römer, Sarah

301 4 p.
artikel
87 Targeting HNRNPA2B1 to overcome chemotherapy resistance in gastric cancer stem cells: Mechanisms and therapeutic potential Yu, Miao

301 4 p.
artikel
88 The catalytic tetrad of Aedes aegypti argonaute 2 is critical for the antiviral activity of the exogenous siRNA pathway Dummunee, Krittika

301 4 p.
artikel
89 The contribution of the Golgi and the endoplasmic reticulum to calcium and pH homeostasis in Toxoplasma gondii Calixto, Abigail

301 4 p.
artikel
90 The E3 ubiquitin ligase RNF126 facilitates quality control of unimported mitochondrial membrane proteins Liu, Di

301 4 p.
artikel
91 The glycolytic enzyme PKM2 regulates inflammatory osteoclastogenesis by modulating STAT3 phosphorylation Li, Mingjuan

301 4 p.
artikel
92 The 2-methylcitrate cycle and the glyoxylate shunt in Pseudomonas aeruginosa are linked through enzymatic redundancy Wijaya, Andre J.

301 4 p.
artikel
93 The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 box B DeBono, Nicholas J.

301 4 p.
artikel
94 The ROGDI protein mutated in Kohlschutter–Tonz syndrome is a novel subunit of the Rabconnectin-3 complex implicated in V-ATPase assembly Winkley, Samuel R.

301 4 p.
artikel
95 The structural basis of substrate selectivity of the acinetobactin biosynthetic adenylation domain, BasE Ahmed, Syed Fardin

301 4 p.
artikel
96 The structural basis of TRIM25-mediated regulation of RIG-I Li, Yunlong

301 4 p.
artikel
97 Upregulation of the interferon-inducible antiviral gene RSAD2 in neuroendocrine prostate cancer via PVT1 exon 9 dependent and independent pathways Bonacci, Rachel E.

301 4 p.
artikel
98 Utility of binding protein fusions to immunoglobulin heavy chain constant regions from mammalian and avian species Zhu, Ningyu

301 4 p.
artikel
99 Viperin expression leads to downregulation of mitochondrial genes through misincorporation of ddhCTP by mitochondrial RNA polymerase Majhi, Srijoni

301 4 p.
artikel
100 YibN, a bona fide interactor of the bacterial YidC insertase with effects on membrane protein insertion and membrane lipid production Zhao, Zhiyu

301 4 p.
artikel
                             100 gevonden resultaten
 
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