Digitale Bibliotheek
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                             128 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A BRAF-activated noncoding RNA attenuates clear cell renal cell carcinoma via repression of glucose-6-phosphate dehydrogenase Liu, Wenjing

301 3 p.
artikel
2 A conserved chaperone protein is required for the formation of a noncanonical type VI secretion system spike tip complex Sachar, Kartik

301 3 p.
artikel
3 A CRISPR-edited isoform of the AMPK kinase LKB1 improves the response to cisplatin in A549 lung cancer cells Severino, Matheus Brandemarte

301 3 p.
artikel
4 Aggregated proinsulin in pancreatic β-cells is degraded by the autophagy pathway Madey, Yueh-Fu

301 3 p.
artikel
5 Amyloid precursor protein promotes MASH progression by upregulating death receptor 6–mediated hepatocyte apoptosis Guo, Yanjun

301 3 p.
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6 Anaplerosis by medium-chain fatty acids through complex interplay with glucose and glutamine metabolism German, Hannah M.

301 3 p.
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7 An engineered palivizumab IgG2 subclass for synthetic gp130 and fas-mediated signaling Wittich, Christoph

301 3 p.
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8 AnimalGWASAtlas: Annotation and prioritization of GWAS loci and quantitative trait loci for animal complex traits Gou, Yuwei

301 3 p.
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9 An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4 Bhaduri, Satarupa

301 3 p.
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10 A novel FOXM1–BCL2A1 axis determines unfavorable response to venetoclax in AML Raghuwanshi, Sanjeev

301 3 p.
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11 Apolipoprotein E3 and E4 isoforms exhibit differing effects in countering endotoxins Puthia, Manoj

301 3 p.
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12 A predictive chromatin architecture nexus regulates transcription and DNA damage repair Bhat, Audesh

301 3 p.
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13 A quantitative intracellular peptide-binding assay reveals recognition determinants and context dependence of short linear motifs Subbanna, Mythili S.

301 3 p.
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14 Aquaporin five deficiency suppresses fatty acid oxidation and delays liver regeneration through the transcription factor PPAR Li, Bin

301 3 p.
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15 A retropepsin-like bacterial protease regulates ribosome modification and polypeptide production Little, Richard H.

301 3 p.
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16 A splicing variant in EFCAB7 hinders ciliary transport and disrupts cardiac development Yang, Xin

301 3 p.
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17 Auranofin induces disulfide bond–mimicking S-Au adducts in protein thiol pairs Quadros Barsé, Laísa

301 3 p.
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18 Binding of small molecules at the P-stalk site of ricin A subunit trigger conformational changes that extend into the active site McLaughlin, John E.

301 3 p.
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19 Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors Ng, Martin Y.

301 3 p.
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20 Biomedical effects of protein arginine methyltransferase inhibitors Cao, Mengtong

301 3 p.
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21 Blocking activation of the C1r zymogen defines a novel mode of complement inhibition Duan, Huiquan

301 3 p.
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22 Cdc42EP3-bound septin scaffolds promote actin polymerization Tomasso, Meagan R.

301 3 p.
artikel
23 CD38 mediates nicotinamide mononucleotide base exchange to yield nicotinic acid mononucleotide Madawala, Romanthi

301 3 p.
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24 Characterization of the putative yeast mitochondrial triacylglycerol lipase Tgl2 Tiku, Vitasta

301 3 p.
artikel
25 Charge screening and hydrophobicity drive progressive assembly and liquid–liquid phase separation of reflectin protein Gordon, Reid

301 3 p.
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26 Collagen remodeling-mediated signaling pathways and their impact on tumor therapy Yuan, Zihang

301 3 p.
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27 Colorectal cancer hot spot mutations attenuate the ASXL-MLL4 interaction Biswas, Soumi

301 3 p.
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28 Combined deletion of cytosolic 5′-nucleotidases IA and II lowers glycemia by improving skeletal muscle insulin action and lowering hepatic glucose production Jacobs, Roxane

301 3 p.
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29 Complement-activated fragment Ba functions as an antibacterial protein and mediates immune responses in lower vertebrates Jin, Xiao-yan

301 3 p.
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30 Correction: A putative cAMP-binding protein in Trypanosoma brucei cooperates with FLAM3 to promote flagellar connection and cell morphogenesis Zhou, Qing

301 3 p.
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31 Correction: Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression Wang, Dandan

301 3 p.
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32 Correction: KLF6 activates Sp1-mediated prolidase transcription during TGF-β1 signaling Eni-Aganga, Ireti

301 3 p.
artikel
33 Correction: Three prime repair exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural, and conformational properties Prakash, Prem

301 3 p.
artikel
34 Cover
301 3 p.
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35 Crystal structure of cytochrome P450 NysL and the structural basis for stereo- and regio-selective oxidation of antifungal macrolides Murarka, Vidhi C.

301 3 p.
artikel
36 Cyclophilin J limits linear ubiquitin signaling and controls colorectal cancer progression Sheng, Chunjie

301 3 p.
artikel
37 Dehydrometabolites of siphonaxanthin, a carotenoid from green algae, suppress toll-like receptor 1/2-induced inflammatory response more strongly than siphonaxanthin Manabe, Yuki

301 3 p.
artikel
38 Dengue virus is particularly sensitive to interference with long-chain fatty acid elongation and desaturation Hehner, Julia

301 3 p.
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39 Dentin sialoprotein acts as an angiogenic factor through association with the membrane receptor endoglin Xu, Ximin

301 3 p.
artikel
40 Differential producibility analysis reveals drug-associated carbon and nitrogen metabolite expressions in Mycobacterium tuberculosis Xu, Ye

301 3 p.
artikel
41 Differential substrate specificity of ERK, JNK, and p38 MAP kinases toward connexin 43 Latchford, Lauren P.

301 3 p.
artikel
42 Discovery and characterization of an FAD-dependent glucose 6-dehydrogenase Fujii, Takahiro

301 3 p.
artikel
43 Downregulation of the phosphatase PHLPP1 contributes to NNK-induced malignant transformation of human bronchial epithelial cells (HBECs) Liu, Xuelei

301 3 p.
artikel
44 Drosophila Modulo is essential for transposon silencing and developmental robustness Parikh, Rasesh Y.

301 3 p.
artikel
45 Drug resistance–associated mutations in Plasmodium UBP-1 disrupt its essential deubiquitinating activity Smith, Cameron J.

301 3 p.
artikel
46 Emerging approaches to investigating functional protein dynamics in modular redox enzymes: Nitric oxide synthase as a model system Jiang, Ting

301 3 p.
artikel
47 Enhanced kinase translocation reporters for simultaneous real-time measurement of PKA, ERK, and calcium Tsai, Shang-Jui

301 3 p.
artikel
48 Exogenous L-fucose attenuates depression induced by chronic unpredictable stress: Implicating core fucosylation has an antidepressant potential Wang, Dan

301 3 p.
artikel
49 Extremophilic hemoglobins: The structure of Shewanella benthica truncated hemoglobin N Martinez Grundman, Jaime E.

301 3 p.
artikel
50 Functional investigation of a putative calcium-binding site involved in the inhibition of inositol 1,4,5-trisphosphate receptor activity Arige, Vikas

301 3 p.
artikel
51 FXR-ApoC2 pathway activates UCP1-mediated thermogenesis by promoting the browning of white adipose tissues Kim, Sang Hee

301 3 p.
artikel
52 GCIP and SIRT6 cooperatively suppress ITGAV gene expression by modulating c-myc transcription ability Huang, Yi-Ching

301 3 p.
artikel
53 Harmine promotes axon regeneration through enhancing glucose metabolism Liu, Ruixuan

301 3 p.
artikel
54 Heme delivery into soluble guanylyl cyclase requires a heme redox change and is regulated by NO and Hsp90 by distinct mechanisms Dai, Yue

301 3 p.
artikel
55 Hepatocyte growth factor protects against hypoxia/reoxygenation-induced apoptosis in endothelial cells Wang, Xue

301 3 p.
artikel
56 Hypoxia induces ferroptotic cell death mediated by activation of the inner mitochondrial membrane fission protein MTP18/Drp1 in invertebrates Liu, Jiaqi

301 3 p.
artikel
57 Identifying the copper coordination environment between interacting neurodegenerative proteins: A new approach using pulsed EPR with 14N/15N isotopic labeling Smart, Amanda

301 3 p.
artikel
58 Integrative in silico and biochemical analyses demonstrate direct Arl3-mediated ODA16 release from the intraflagellar transport machinery Wang, Jiaolong

301 3 p.
artikel
59 Integrin beta 1 and fibronectin mediate extracellular vesicle uptake and functional RNA delivery Elsharkasy, Omnia M.

301 3 p.
artikel
60 Isolation and structure elucidation of Dm-CVNH, a new cyanovirin-N homolog with activity against SARS-CoV-2 and HIV-1 Orfanoudaki, Maria

301 3 p.
artikel
61 Kinetics insight into the roles of the N- and C-lobes of calmodulin in RyR1 channel regulation Zhang, Jingyan

301 3 p.
artikel
62 Knocking out p38α+p38β+p38γ is required to abort the myogenic program in C2C12 myoblasts and to impose uncontrolled proliferation Mooshayef, Navit

301 3 p.
artikel
63 Leucine 7 is a key residue for mutant huntingtin–induced mitochondrial pathology and neurotoxicity in Huntington's disease Zhang, Shengrong

301 3 p.
artikel
64 Light-chain split luciferase assay implicates pathological NOTCH3 thiol reactivity in inherited cerebral small vessel disease Cartee, Naw May Pearl

301 3 p.
artikel
65 Maresin-1 promotes neuroprotection and modulates metabolic and inflammatory responses in disease-associated cell types in preclinical models of multiple sclerosis Zahoor, Insha

301 3 p.
artikel
66 Mechanisms of dual modulatory effects of spermine on the mitochondrial calcium uniporter complex Tu, Yung-Chi

301 3 p.
artikel
67 Mechanistic insights into mutation in the proton-coupled folate transporter (SLC46A1) causing hereditary folate malabsorption Nandigrami, Prithviraj

301 3 p.
artikel
68 Metformin inhibits the histone methyltransferase CARM1 and attenuates H3 histone methylation during gluconeogenesis Dhang, Sinjini

301 3 p.
artikel
69 MIA40 circumvents the folding constraints imposed by TRIAP1 function Pujols, Jordi

301 3 p.
artikel
70 Mobility of four structural regions drives isoform-specific properties of photoenzyme LPOR in plants Gabruk, Michał

301 3 p.
artikel
71 Modulating the complement system through epitope-specific inhibition by complement C3 inhibitors Chen, Zhidong

301 3 p.
artikel
72 Modulation of the substrate preference of a MYST acetyltransferase by a scaffold protein Sengupta, Raghuvir N.

301 3 p.
artikel
73 Molecular sorting of nitrogenase catalytic cofactors Salinero-Lanzarote, Alvaro

301 3 p.
artikel
74 Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains Olp, Michael D.

301 3 p.
artikel
75 Nanobody fusion enhances production of difficult-to-produce secretory proteins Yan, Runchuan

301 3 p.
artikel
76 N-glycosylation of ephrin B1 modulates its function and confers therapeutic potential in B-cell lymphoma Li, Xiaoxi

301 3 p.
artikel
77 NMR study of the interaction between MinC and FtsZ and modeling of the FtsZ:MinC complex Machado, Luciana E.S.F.

301 3 p.
artikel
78 NUMB alternative splicing and isoform-specific functions in development and disease Dho, Sascha E.

301 3 p.
artikel
79 O-GlcNAc modification differentially regulates microtubule binding and pathological conformations of tau isoforms in vitro Alhadidy, Mohammed M.

301 3 p.
artikel
80 Pathogenic mechanism of abnormal expression of HDAC3 in ovulatory granulosa cells inducing oocyte maturation disorder and its application in IVM Wang, Huarong

301 3 p.
artikel
81 PDE4 inhibitor rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer Bagchi, Arka

301 3 p.
artikel
82 Phosphodiesterase 5 expression in photoreceptors rescues retinal degeneration induced by deregulation of membrane guanylyl cyclase Dizhoor, Alexander M.

301 3 p.
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83 Phosphorylation of distal C-terminal residues promotes TRPV4 channel activation in response to arachidonic acid Parthasarathy, Aravind

301 3 p.
artikel
84 p53-mediated regulation of LINE1 retrotransposon-derived R-loops Paul, Pratyashaa

301 3 p.
artikel
85 Polyamines enhance repeat-associated non-AUG translation from CCUG repeats by stabilizing the tertiary structure of RNA Oguro, Akihiro

301 3 p.
artikel
86 Profiling Tel1 signaling reveals a non-canonical motif targeting DNA repair and telomere control machineries Comstock, William J.

301 3 p.
artikel
87 P3 site-directed mutagenesis: An efficient method based on primer pairs with 3′-overhangs Mousavi, Negar

301 3 p.
artikel
88 Rad5 and Ubc4 directly ubiquitinate PCNA at Lys164 in vitro Hu, Yixiong

301 3 p.
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89 Recombinant antibodies inhibit enzymatic activity of the E3 ubiquitin ligase CHIP via multiple mechanisms Chung, Dong hee

301 3 p.
artikel
90 REDD1-dependent GSK3β signaling in podocytes promotes canonical NF-κB activation in diabetic nephropathy Sunilkumar, Siddharth

301 3 p.
artikel
91 Regulation of respiratory syncytial virus nucleoprotein oligomerization by phosphorylation Basse, Vincent

301 3 p.
artikel
92 RNA G-quadruplexes regulate mammalian mirtron biogenesis Salim, Uzma

301 3 p.
artikel
93 Sensitive detection and propagation of brain-derived tau assemblies in HEK293-based wild-type tau seeding assays Huang, Melissa

301 3 p.
artikel
94 Single-cell metabolomics profiling of somatosensory neurons in various stages of neuropathic pain Yi, Lin

301 3 p.
artikel
95 SlMYB72 and SlMYB75 antagonistically regulate trichome formation via the MYB-bHLH-WD40 complex in tomato Qi, Tiancheng

301 3 p.
artikel
96 Sodium proton exchanger NHE9 pHine-tunes exosome production by impairing Rab7 activity Duhaini, Mariam

301 3 p.
artikel
97 Spider-derived peptide LCTx-F2 suppresses ASIC channels by occupying the acidic pocket Du, Canwei

301 3 p.
artikel
98 Stabilized designs of the malaria adhesin protein PvRBP2b for use as a potential diagnostic for Plasmodium vivax D Sa, Jaison

301 3 p.
artikel
99 Staufen2 dysregulation in neurodegenerative disease Paul, Sharan

301 3 p.
artikel
100 Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain Castro, Anthony

301 3 p.
artikel
101 Structural insights into 2-oxindole-forming monooxygenase MarE: Divergent architecture and substrate positioning versus tryptophan dioxygenases Shin, Inchul

301 3 p.
artikel
102 Structure of a mutated photosystem II complex reveals changes to the hydrogen-bonding network that affect proton egress during O–O bond formation Flesher, David A.

301 3 p.
artikel
103 Sulfoglycolysis sustains Eubacterium rectale in low-fiber diets Sharma, Mahima

301 3 p.
artikel
104 Surface hydrophobic clusters modulate the folding stability and molecular recognition of the disintegrin jarastatin Vasconcelos, Ariana A.

301 3 p.
artikel
105 Surveying helix 12 dynamics within constitutively active estrogen receptors using bipartite tetracysteine display Sendanayake, Lasantha R.

301 3 p.
artikel
106 Synthetic mycolates derivatives to decipher protein mycoloylation, a unique post-translational modification in bacteria Lesur, Emilie

301 3 p.
artikel
107 Synthetic transcription factors establish the function of nine amino acid transactivation domains of Komagataella phaffii Mxr1 Priya, Prachi

301 3 p.
artikel
108 Tackling pressure fluctuations in ultra-HPLC to robustly resolve and analyze polar metabolites Krycer, James R.

301 3 p.
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109 Taste receptor type 1 member 3 in osteoclasts regulates osteoclastogenesis via detection of glucose Yoshimura, Anna

301 3 p.
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110 TET1 participates in oxaliplatin-induced neuropathic pain by regulating microRNA-30b/Nav1.6 Zhao, Sen

301 3 p.
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111 Tetraspanin CD9 alters cellular trafficking and endocytosis of tetraspanin CD63, affecting CD63 packaging into small extracellular vesicles Duke, Leanne C.

301 3 p.
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112 TFII-I/GTF2I regulates globin gene expression and stress response in erythroid cells Nar, Rukiye

301 3 p.
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113 The common murine retroviral integration site activating Hhex marks a distal regulatory enhancer co-opted in human early T-cell precursor leukemia Hardwick, Joyce

301 3 p.
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114 The glycoprotein GPNMB protects against oxidative stress through enhanced PI3K/AKT signaling in epidermal keratinocytes Nishida, Natsuki

301 3 p.
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115 The juxtamembrane sequence of small ankyrin 1 mediates the binding of its cytoplasmic domain to SERCA1 and is required for inhibitory activity Li, Yi

301 3 p.
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116 The levels of the long noncoding RNA MALAT1 affect cell viability and modulate TDP-43 binding to mRNA in the nucleus Balaji, Adarsh

301 3 p.
artikel
117 The mediator subunit complex protein MED15 promotes lipid deposition and cancer progression during hypoxia Zhang, Boqi

301 3 p.
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118 The regulation of cell metabolism by hypoxia and hypercapnia Reddan, Ben

301 3 p.
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119 The SET29 and SET7 proteins of Leishmania donovani exercise non-redundant convergent as well as collaborative functions in moderating the parasite’s response to oxidative stress Sharma, Varshni

301 3 p.
artikel
120 The Shab family potassium channels are highly enriched at the presynaptic terminals of human neurons Benner, Orion

301 3 p.
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121 The sterol-regulating human ARV1 binds cholesterol and phospholipids through its conserved ARV1 homology domain Cunningham, Jessie Lee

301 3 p.
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122 The yeast checkpoint kinase Dun1p represses transcription of RNR genes independently of catalytic activity or Rad53p during respiratory growth Nagar, Shreya

301 3 p.
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123 Topology-driven discovery of transmembrane protein S-palmitoylation Forrester, Michael T.

301 3 p.
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124 Transmembrane Parkinson’s disease mutation of PINK1 leads to altered mitochondrial anchoring Brassard, Raelynn

301 3 p.
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125 Two ligands of Arp2/3 complex, yeast coronin and GMF, interact and synergize in pruning branched actin networks Koundinya, Neha

301 3 p.
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126 Txnip deficiency causes a susceptibility to acute cold stress with brown fat dysfunction in mice Zou, Meng

301 3 p.
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127 USP1 promotes pancreatic cancer progression and autophagy by deubiquitinating ATG14 Li, Leilei

301 3 p.
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128 Withdrawal: RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with βArrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the β2-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells Lynch, Martin J.

301 3 p.
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                             128 gevonden resultaten
 
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