Digitale Bibliotheek
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                             85 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Aberrant Wnt/β-catenin signaling in the mesenchymal stem cells of LZTFL1-depleted mice leads to increased adipogenesis, with implications for obesity Badralmaa, Yunden

301 1 p.
artikel
2 A conserved acidic residue drives thyroxine synthesis within thyroglobulin and other protein precursors Stejskalova, Camilla

301 1 p.
artikel
3 ADP-ribosyltransferase-based biocatalysis of nonhydrolyzable NAD+ analogs Sakari, Moona

301 1 p.
artikel
4 A kinetic model for compound heterozygous pathogenic variants in Tyrosyl-tRNA synthetase gene YARS2-Associated neonatal phenotype Christian, Thomas

301 1 p.
artikel
5 Allosteric modulation of the Lon protease via ssDNA binding and local charge changes Ogdahl, Justyne L.

301 1 p.
artikel
6 Alternative splicing is an FXRα loss-of-function mechanism and impacts energy metabolism in hepatocarcinoma cells Garcia, Manon

301 1 p.
artikel
7 A more holistic view of the logarithmic dose–response curve offers greater insights into insulin responses Wang, Guanyu

301 1 p.
artikel
8 An anomalous abundance of tryptophan residues in ceramide synthases based on analysis of all membrane proteins in the Swiss-Prot database Mestre, Beatriz

301 1 p.
artikel
9 An oncoprotein CREPT functions as a co-factor in MYC-driven transformation and tumor growth Li, Mengdi

301 1 p.
artikel
10 An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck Selzer, Ari M.

301 1 p.
artikel
11 Apoptotic signaling by TNFR1 is inhibited by the α2-6 sialylation, but not α2-3 sialylation, of the TNFR1 N-glycans Hwang, Jihye

301 1 p.
artikel
12 Biased constitutive signaling of the G protein-coupled receptor GPR35 suppresses gut barrier permeability Quon, Tezz

301 1 p.
artikel
13 Chaperone-mediated disaggregation of infectious prions releases particles that seed new prion formation in a strain-specific manner Shoup, Daniel

301 1 p.
artikel
14 Chelerythrine triggers the prolongation of QT interval and induces cardiotoxicity by promoting the degradation of hERG channels Wang, Fang

301 1 p.
artikel
15 Cover
301 1 p.
artikel
16 Crystallographic, kinetic, and calorimetric investigation of PKA interactions with L-type calcium channels and Rad GTPase Yoo, Randy

301 1 p.
artikel
17 CspZ variant–specific interaction with factor H incorporates a metal site to support Lyme borreliae complement evasion Brangulis, Kalvis

301 1 p.
artikel
18 Deep phenotyping of T regulatory cells in psoriatic arthritis highlights targetable mechanisms of disease McTaggart, Tegan

301 1 p.
artikel
19 Diarylamidine activation of a brachiopod DEG/ENaC/ASIC channel Martí-Solans, Josep

301 1 p.
artikel
20 Distinct autoregulatory roles of ELFN1 intracellular and extracellular domains on membrane trafficking, synaptic localization, and dimerization Dunn, Henry A.

301 1 p.
artikel
21 Downregulation of the splicing regulator NSRP1 confers resistance to CDK4/6 inhibitors via activation of interferon signaling in breast cancer Yu, Shiyi

301 1 p.
artikel
22 Dual-ligand fluorescence microscopy enables chronological and spatial histological assignment of distinct amyloid-β deposits Klingstedt, Therése

301 1 p.
artikel
23 Dynamic O-GlcNAcylation coordinates etoposide-triggered tumor cell pyroptosis by regulating p53 stability Wang, Jing

301 1 p.
artikel
24 Dysregulation of PI4P in the trans Golgi regions activates the mammalian Golgi stress response Sasaki, Kanae

301 1 p.
artikel
25 E2F1 and E2F7 regulate gastric cancer cell proliferation, respectively, through transcriptional activation and transcriptional repression of MYBL2 Wu, Tianyi

301 1 p.
artikel
26 Energy metabolism in osteoprogenitors and osteoblasts: Role of the pentose phosphate pathway Catheline, Sarah E.

301 1 p.
artikel
27 Epigenetic activation of JAG1 by AID contributes to metastasis of hepatocellular carcinoma Jiao, Junna

301 1 p.
artikel
28 Epitope mapping via in vitro deep mutational scanning methods and its applications Keen, Meredith M.

301 1 p.
artikel
29 Glutamine metabolism is essential for coronavirus replication in host cells and in mice Greene, Kai Su

301 1 p.
artikel
30 High-affinity ELR+ chemokine ligands show G protein bias over β-arrestin recruitment and receptor internalization in CXCR1 signaling Boon, Katrijn

301 1 p.
artikel
31 Histone variants: The bricks that fit differently Hegazy, Youssef A.

301 1 p.
artikel
32 Hyperactivation of human acidic chitinase (Chia) for potential medical use Okawa, Kazuaki

301 1 p.
artikel
33 Independent evolution of plant natural products: Formation of benzoxazinoids in Consolida orientalis (Ranunculaceae) Florean, Matilde

301 1 p.
artikel
34 Inhibition of the neddylation E2 enzyme UBE2M in macrophages protects against E. coli-induced sepsis Wen, Xuehuan

301 1 p.
artikel
35 β1-integrin controls IGF-1R internalization and intracellular signaling McDermott, Niamh

301 1 p.
artikel
36 Interplay of niche and respiratory network in shaping bacterial colonization Srivastav, Stuti

301 1 p.
artikel
37 Iron regulatory protein 1-deficient mice exhibit hypospermatogenesis Harrer, Aileen

301 1 p.
artikel
38 Lipids determine the toxicity of human islet polypeptide aggregates in vivo Sitton, Jadon

301 1 p.
artikel
39 Mammalian hydroxylation of microbiome-derived obesogen, delta-valerobetaine, to homocarnitine, a 5-carbon carnitine analog Weinberg, Jaclyn

301 1 p.
artikel
40 Mechanistic insights into the selective targeting of P2X3 receptor by camlipixant antagonist Thach, Trung

301 1 p.
artikel
41 Metabolic control of luteinizing hormone-responsive ovarian steroidogenesis Przygrodzka, Emilia

301 1 p.
artikel
42 Misfolding of transthyretin in vivo is controlled by the redox environment and macromolecular crowding Jayaweera, Sanduni Wasana

301 1 p.
artikel
43 Molecular determinants of the selectivity and potency of α-conotoxin Vc1.1 for human nicotinic acetylcholine receptors Tae, Han-Shen

301 1 p.
artikel
44 mRNA vaccine sequence and structure design and optimization: Advances and challenges Jin, Lei

301 1 p.
artikel
45 Multiple gating processes associated with the distal end of the S6 segment of domain II in the Nav channels Chen, Minzhi

301 1 p.
artikel
46 Mutations in the essential outer membrane protein BamA contribute to Escherichia coli resistance to the antimicrobial peptide TAT-RasGAP317-326 Georgieva, Maria

301 1 p.
artikel
47 One-for-all gene inactivation via PAM-independent base editing in bacteria Li, Xin

301 1 p.
artikel
48 p38α and p38β regulate osmostress-induced apoptosis Ben Messaoud, Nabil

301 1 p.
artikel
49 Pharmacological and structural understanding of the Trypanosoma cruzi proteasome provides key insights for developing site-specific inhibitors Eadsforth, Thomas C.

301 1 p.
artikel
50 Phase partitioning of the neutrophil oxidative burst is coordinated by accessory pathways of glucose metabolism and mitochondrial activity Jobe, Tyler

301 1 p.
artikel
51 Phosphorylation of Ephexin4 at Ser-41 contributes to chromosome alignment via RhoG activation in cell division Yasutake, Ryuji

301 1 p.
artikel
52 Phosphorylation of Lamin A/C regulates the structural integrity of the nuclear envelope Liu, Shuaiyu

301 1 p.
artikel
53 PRDX4 mitigates diabetic retinopathy by inhibiting reactive gliosis, apoptosis, ER stress, oxidative stress, and mitochondrial dysfunction in Müller cells Huang, Yue

301 1 p.
artikel
54 Prohibitin 1 tethers lipid membranes and regulates OPA1-mediated membrane fusion Ban, Tadato

301 1 p.
artikel
55 Proteomic study identifies Aurora-A–mediated regulation of alternative splicing through multiple splicing factors Damodaran, Arun Prasath

301 1 p.
artikel
56 Purification of micrococcal nuclease for use in ribosomal profiling of high-salinity extremophiles Gregorova, Pavlina

301 1 p.
artikel
57 Quiescent cells maintain active degradation-mediated protein quality control requiring proteasome, autophagy, and nucleus-vacuole junctions Franić, Dina

301 1 p.
artikel
58 Reactivation and long-term stabilization of the [NiFe] Hox hydrogenase of Synechocystis sp. PCC6803 by glutathione after oxygen exposure Romig, Merle

301 1 p.
artikel
59 Redirecting E3 ubiquitin ligases for targeted protein degradation with heterologous recognition domains Yang, Huan

301 1 p.
artikel
60 Regulation of de novo and maintenance DNA methylation by DNA methyltransferases in postimplantation embryos Xu, Zhen

301 1 p.
artikel
61 Regulation of the chemokine receptors CXCR4 and ACKR3 by receptor activity-modifying proteins Pfersdorf, Fabian

301 1 p.
artikel
62 Small molecule-based regulation of gene expression in human astrocytes switching on and off the G-quadruplex control systems M. J, Vijay Kumar

301 1 p.
artikel
63 Spatial chromosome organization and adaptation of the radiation-resistant extremophile Deinococcus radiodurans Qiu, Qin-Tian

301 1 p.
artikel
64 Structural and functional properties of the N- and C-terminal segments of the P4-ATPase phospholipid flippase ATP8A2 Matsell, Eli

301 1 p.
artikel
65 Structural basis for Rab23 activation and a loss-of-function mutation in Carpenter syndrome Chau, Yat Yin

301 1 p.
artikel
66 Structural basis for the pathogenicity of parkin catalytic domain mutants Wagner, Julian P.

301 1 p.
artikel
67 Targeting cytoskeletal biomechanics to modulate airway smooth muscle contraction in asthma McCullough, Morgan

301 1 p.
artikel
68 The globular domain of extracellular histones mediates cytotoxicity via membrane disruption mechanism Pan, Yixuan

301 1 p.
artikel
69 The host restriction factor SERINC5 inhibits HIV-1 transcription by negatively regulating NF-κB signaling Li, Weiting

301 1 p.
artikel
70 The mechanism of Ca2+-independent activation of BKCa channels in mouse inner hair cells and the crucial role of the BK channels in auditory perception Shen, Zhong-Shan

301 1 p.
artikel
71 The mode of subunit addition regulates the processive elongation of actin filaments by formin Mahanta, Biswaprakash

301 1 p.
artikel
72 The physicochemical properties of lipopolysaccharide chemotypes regulate activation of the contact pathway of blood coagulation Lira, André L.

301 1 p.
artikel
73 The putative polyamine transporter Shp2 facilitates phosphate export in an Xpr1-independent manner and contributes to high phosphate tolerance Komamura, Tochi

301 1 p.
artikel
74 The serine protease DPP9 and the redox sensor KEAP1 form a mutually inhibitory complex Tsamouri, Lydia P.

301 1 p.
artikel
75 The signaling landscape of insulin-like growth factor 1 Khan, Muhammad Zahid

301 1 p.
artikel
76 The steroid hormone 20-hydroxyecdysone inhibits RAPTOR expression by repressing Hox gene transcription to induce autophagy Liu, Tian-Wen

301 1 p.
artikel
77 The structural basis for high-affinity c-di-GMP binding to the GSPII-B domain of the traffic ATPase PilF from Thermus thermophilus Neißner, Konstantin

301 1 p.
artikel
78 The transcription factor CREB regulates epithelial-mesenchymal transition of lens epithelial cells by phosphorylation-dependent and phosphorylation-independent mechanisms Zhang, Lan

301 1 p.
artikel
79 The use of Mg2+ in investigations of the roles of intramitochondrial Ca2+ and the mitochondrial Ca2+-uniporter in the stimulation of oxidative phosphorylation Rendon, Dairo Alonso

301 1 p.
artikel
80 The zymogenic form of SARS-CoV-2 main protease: A discrete target for drug discovery Novotný, Pavel

301 1 p.
artikel
81 Thrombin confers chemotherapeutic resistance by promoting transcriptional induction and post-translational stabilization of pro-survival MCL1 in TNBC Paul, Subhojit

301 1 p.
artikel
82 Transcription factor TCF7L1 targeting HSPB6 is involved in EMT and PI3K/AKT/mTOR pathways in bladder cancer Li, Zizhi

301 1 p.
artikel
83 Transferrin ameliorates retinal degeneration by mediating the dimerization of all-trans-retinal Tao, Lei

301 1 p.
artikel
84 Unveiling 14 novel 2-hydroxy acid racemization and epimerization reactions in the lactate racemase superfamily Urdiain-Arraiza, Julian

301 1 p.
artikel
85 Withdrawal: Neutralization of RANTES and eotaxin prevents the loss of dopaminergic neurons in a mouse model of Parkinson disease Chandra, Goutam

301 1 p.
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                             85 gevonden resultaten
 
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