| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
AAV-mediated hepatic expression of SLC30A10 and the Thr95Ile variant attenuates manganese excess and other phenotypes in Slc30a10-deficient mice
|
Prajapati, Milankumar
|
|
|
300 |
3 |
p.
|
artikel
|
| 2 |
Actin associates with actively elongating genes and binds directly to the Cdk9 subunit of P-TEFb
|
Kyheröinen, Salla
|
|
|
300 |
3 |
p.
|
artikel
|
| 3 |
Activation of innate immune receptor TLR9 by mitochondrial DNA plays essential roles in the chemical long-term depression of hippocampal neurons
|
Atarashi, Naoya
|
|
|
300 |
3 |
p.
|
artikel
|
| 4 |
A KDELR-mediated ER-retrieval system modulates mitochondrial functions via the unfolded protein response in fission yeast
|
Zhu, Mengdan
|
|
|
300 |
3 |
p.
|
artikel
|
| 5 |
A multiscale approach reveals the molecular architecture of the autoinhibited kinesin KIF5A
|
Carrington, Glenn
|
|
|
300 |
3 |
p.
|
artikel
|
| 6 |
Analysis of Poly(ethylene terephthalate) degradation kinetics of evolved IsPETase variants using a surface crowding model
|
Zhong-Johnson, En Ze Linda
|
|
|
300 |
3 |
p.
|
artikel
|
| 7 |
A PilZ domain protein interacts with the transcriptional regulator HinK to regulate type VI secretion system in Pseudomonas aeruginosa
|
Cheng, Tianfang
|
|
|
300 |
3 |
p.
|
artikel
|
| 8 |
AP-1γ2 is an adaptor protein 1 variant required for endosome-to-Golgi trafficking of the mannose-6-P receptor (CI-MPR) and ATP7B copper transporter
|
Tavares, Lucas Alves
|
|
|
300 |
3 |
p.
|
artikel
|
| 9 |
Biochemical and cellular characterization of the CISD3 protein: Molecular bases of cluster release and destabilizing effects of nitric oxide
|
Grifagni, Deborah
|
|
|
300 |
3 |
p.
|
artikel
|
| 10 |
Both Las17-binding sites on Arp2/3 complex are important for branching nucleation and assembly of functional endocytic actin networks in S. cerevisiae
|
Narvaez-Ortiz, Heidy Y.
|
|
|
300 |
3 |
p.
|
artikel
|
| 11 |
Bulky hydrophobic side chains in the β1-sandwich of microsomal triglyceride transfer protein are critical for the transfer of both triglycerides and phospholipids
|
Anaganti, Narasimha
|
|
|
300 |
3 |
p.
|
artikel
|
| 12 |
Charge neutralization and β-elimination cleavage mechanism of family 42 L-rhamnose-α-1,4-D-glucuronate lyase revealed using neutron crystallography
|
Yano, Naomine
|
|
|
300 |
3 |
p.
|
artikel
|
| 13 |
CHEK2 germline variants identified in familial nonmedullary thyroid cancer lead to impaired protein structure and function
|
Pires, Carolina
|
|
|
300 |
3 |
p.
|
artikel
|
| 14 |
CHIP suppresses the proliferation and migration of A549 cells by mediating the ubiquitination of eIF2α and upregulation of tumor suppressor RBM5
|
Jin, Bo
|
|
|
300 |
3 |
p.
|
artikel
|
| 15 |
Chondroitin sulfate modification of CSPG4 regulates the maintenance and differentiation of glioma-initiating cells via integrin-associated signaling
|
Niibori-Nambu, Akiko
|
|
|
300 |
3 |
p.
|
artikel
|
| 16 |
Chromosomal passenger complex condensates generate parallel microtubule bundles in vitro
|
Niedzialkowska, Ewa
|
|
|
300 |
3 |
p.
|
artikel
|
| 17 |
Coevolution of RNA and protein subunits in RNase P and RNase MRP, two RNA processing enzymes
|
Zhou, Bin
|
|
|
300 |
3 |
p.
|
artikel
|
| 18 |
Compartmentalization of galactan biosynthesis in mycobacteria
|
Savková, Karin
|
|
|
300 |
3 |
p.
|
artikel
|
| 19 |
Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing
|
Singh, Rahul
|
|
|
300 |
3 |
p.
|
artikel
|
| 20 |
Correction: Kindlin-2 maintains liver homeostasis by regulating GSTP1-OPN-mediated oxidative stress and inflammation in mice
|
Zhong, Yiming
|
|
|
300 |
3 |
p.
|
artikel
|
| 21 |
Correction: Protein kinase A-mediated phosphorylation of the broad-complex transcription factor in silkworm suppresses its transcriptional activity
|
Qian, Wenliang
|
|
|
300 |
3 |
p.
|
artikel
|
| 22 |
Cover
|
|
|
|
300 |
3 |
p.
|
artikel
|
| 23 |
Crystal structure of tick tyrosylprotein sulfotransferase reveals the activation mechanism of the tick anticoagulant protein madanin
|
Yoshimura, Misa
|
|
|
300 |
3 |
p.
|
artikel
|
| 24 |
Decreased pyruvate dehydrogenase activity in Tafazzin-deficient cells is caused by dysregulation of pyruvate dehydrogenase phosphatase 1 (PDP1)
|
Liang, Zhuqing
|
|
|
300 |
3 |
p.
|
artikel
|
| 25 |
Differential responses to UCP1 ablation in classical brown versus beige fat, despite a parallel increase in sympathetic innervation
|
Naren, Qimuge
|
|
|
300 |
3 |
p.
|
artikel
|
| 26 |
Dirigent isoflavene-forming PsPTS2: 3D structure, stereochemical, and kinetic characterization comparison with pterocarpan-forming PsPTS1 homolog in pea
|
Meng, Qingyan
|
|
|
300 |
3 |
p.
|
artikel
|
| 27 |
Discovery and engineering of AiEvo2, a novel Cas12a nuclease for human gene editing applications
|
Sharrar, Allison
|
|
|
300 |
3 |
p.
|
artikel
|
| 28 |
Discovery and structural characterization of the D-box, a conserved TonB motif that couples an inner-membrane motor to outer-membrane transport
|
Loll, Patrick J.
|
|
|
300 |
3 |
p.
|
artikel
|
| 29 |
Discovery, structure, mechanisms, and evolution of protein-only RNase P enzymes
|
Rossmanith, Walter
|
|
|
300 |
3 |
p.
|
artikel
|
| 30 |
eIF5 stimulates the CUG initiation of RAN translation of poly-GA dipeptide repeat protein (DPR) in C9orf72 FTLD/ALS
|
Gotoh, Shiho
|
|
|
300 |
3 |
p.
|
artikel
|
| 31 |
Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells
|
Wilson, Rachel B.
|
|
|
300 |
3 |
p.
|
artikel
|
| 32 |
Emerging roles of O-GlcNAcylation in protein trafficking and secretion
|
Zhang, Jianchao
|
|
|
300 |
3 |
p.
|
artikel
|
| 33 |
Engineering of glycoside hydrolase family 7 cellobiohydrolases directed by natural diversity screening
|
Brunecky, Roman
|
|
|
300 |
3 |
p.
|
artikel
|
| 34 |
E3 ubiquitin ligase Hul6 modulates iron-dependent metabolism by regulating Php4 stability
|
Yao, Rui
|
|
|
300 |
3 |
p.
|
artikel
|
| 35 |
E3 ubiquitin ligase rififylin has yin and yang effects on rabbit cardiac transient outward potassium currents (I to) and corresponding channel proteins
|
Kabakov, Anatoli Y.
|
|
|
300 |
3 |
p.
|
artikel
|
| 36 |
Evolution of a novel regulatory mechanism of hypoxia inducible factor in hypoxia-tolerant electric fishes
|
Elbassiouny, Ahmed A.
|
|
|
300 |
3 |
p.
|
artikel
|
| 37 |
Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands
|
Macdonald-Obermann, Jennifer L.
|
|
|
300 |
3 |
p.
|
artikel
|
| 38 |
Factors governing the transcriptome changes and chronological lifespan of fission yeast during phosphate starvation
|
Garg, Angad
|
|
|
300 |
3 |
p.
|
artikel
|
| 39 |
Fecal-adherent mucus is a non-invasive source of primary human MUC2 for structural and functional characterization in health and disease
|
Fancy, Noah
|
|
|
300 |
3 |
p.
|
artikel
|
| 40 |
Flipping the script: Understanding riboswitches from an alternative perspective
|
Olenginski, Lukasz T.
|
|
|
300 |
3 |
p.
|
artikel
|
| 41 |
FOXS1 is increased in liver fibrosis and regulates TGFβ responsiveness and proliferation pathways in human hepatic stellate cells
|
Bates, Evelyn A.
|
|
|
300 |
3 |
p.
|
artikel
|
| 42 |
Functional diversification of cell signaling by GPCR localization
|
Klauer, Matthew J.
|
|
|
300 |
3 |
p.
|
artikel
|
| 43 |
Functional domains of a ribosome arresting peptide are affected by surrounding nonconserved residues
|
Judd, Heather N.G.
|
|
|
300 |
3 |
p.
|
artikel
|
| 44 |
Genotype-dependent N-glycosylation and newly exposed O-glycosylation affect plasmin-induced cleavage of histidine-rich glycoprotein (HRG)
|
Zou, Yang
|
|
|
300 |
3 |
p.
|
artikel
|
| 45 |
G protein–coupled estrogen receptor 1 ameliorates nonalcoholic steatohepatitis through targeting AMPK-dependent signaling
|
Li, Longlong
|
|
|
300 |
3 |
p.
|
artikel
|
| 46 |
Helical domain of hGBP3 cannot stimulate the second phosphate cleavage of GTP
|
Rashmi, Divya
|
|
|
300 |
3 |
p.
|
artikel
|
| 47 |
Heterotrimeric G protein signaling without GPCRs: The Gα-binding-and-activating (GBA) motif
|
Garcia-Marcos, Mikel
|
|
|
300 |
3 |
p.
|
artikel
|
| 48 |
Histone H3Y99sulf regulates hepatocellular carcinoma responding to hypoxia
|
Yin, Sibi
|
|
|
300 |
3 |
p.
|
artikel
|
| 49 |
Host antimicrobial peptide S100A12 disrupts the fungal membrane by direct binding and inhibits growth and biofilm formation of Fusarium species
|
Roy, Sanhita
|
|
|
300 |
3 |
p.
|
artikel
|
| 50 |
HuR–miRNA complex activates RAS GTPase RalA to facilitate endosome targeting and extracellular export of miRNAs
|
Ghosh, Syamantak
|
|
|
300 |
3 |
p.
|
artikel
|
| 51 |
Identification of a conserved α-helical domain at the N terminus of human DNA methyltransferase 1
|
Hu, Qi
|
|
|
300 |
3 |
p.
|
artikel
|
| 52 |
Identification of RSK substrates using an analog-sensitive kinase approach
|
Lizcano-Perret, Belén
|
|
|
300 |
3 |
p.
|
artikel
|
| 53 |
Impaired lysosomal acidity maintenance in acid lipase-deficient cells leads to defective autophagy
|
Moriwaki, Takahito
|
|
|
300 |
3 |
p.
|
artikel
|
| 54 |
Inhibition of protein kinase C increases Prdm14 level to promote self-renewal of embryonic stem cells through reducing Suv39h-induced H3K9 methylation
|
Ji, Junxiang
|
|
|
300 |
3 |
p.
|
artikel
|
| 55 |
Interaction of human dendritic cell receptor DEC205/CD205 with keratins
|
Kong, Dandan
|
|
|
300 |
3 |
p.
|
artikel
|
| 56 |
14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway
|
Mukherjee, Soumita
|
|
|
300 |
3 |
p.
|
artikel
|
| 57 |
Intracellular trafficking of HIV-1 Gag via Syntaxin 6-positive compartments/vesicles: Involvement in tumor necrosis factor secretion
|
Tsurutani, Naomi
|
|
|
300 |
3 |
p.
|
artikel
|
| 58 |
KAT8 is upregulated and recruited to the promoter of Atg8 by FOXO to induce H4 acetylation for autophagy under 20-hydroxyecdysone regulation
|
Liu, Tian-Wen
|
|
|
300 |
3 |
p.
|
artikel
|
| 59 |
Klebicin E, a pore-forming bacteriocin of Klebsiella pneumoniae, exploits the porin OmpC and the Ton system for translocation
|
Zhao, Xinxin
|
|
|
300 |
3 |
p.
|
artikel
|
| 60 |
Komagataella phaffii Erp41 is a protein disulfide isomerase with unprecedented disulfide bond catalyzing activity when coupled to glutathione
|
Palma, Arianna
|
|
|
300 |
3 |
p.
|
artikel
|
| 61 |
Leishmania profilin interacts with actin through an unusual structural mechanism to control cytoskeletal dynamics in parasites
|
Vizcaíno-Castillo, Andrea
|
|
|
300 |
3 |
p.
|
artikel
|
| 62 |
LncRNA CHROMR/miR-27b-3p/MET axis promotes the proliferation, invasion, and contributes to rituximab resistance in diffuse large B-cell lymphoma
|
Liu, Chang
|
|
|
300 |
3 |
p.
|
artikel
|
| 63 |
Loss of Dna2 fidelity results in decreased Exo1-mediated resection at DNA double-strand breaks
|
Mojumdar, Aditya
|
|
|
300 |
3 |
p.
|
artikel
|
| 64 |
Mating-induced increase of kynurenine in Drosophila ovary enhances starvation resistance of progeny
|
Hikawa, Naoto
|
|
|
300 |
3 |
p.
|
artikel
|
| 65 |
Mechanistic insights into the C-type lectin receptor CLEC12A-mediated immune recognition of monosodium urate crystal
|
Tang, Hua
|
|
|
300 |
3 |
p.
|
artikel
|
| 66 |
Methionine sulfoxide reductase 2 regulates Cvt autophagic pathway by altering the stability of Atg19 and Ape1 in Saccharomyces cerevisiae
|
Chatterjee, Arpan
|
|
|
300 |
3 |
p.
|
artikel
|
| 67 |
Methyl vinyl ketone and its analogs covalently modify PI3K and alter physiological functions by inhibiting PI3K signaling
|
Morimoto, Atsushi
|
|
|
300 |
3 |
p.
|
artikel
|
| 68 |
“Mix and match” auto-assembly of glycosyltransferase domains delivers biocatalysts with improved substrate promiscuity
|
Bretagne, Damien
|
|
|
300 |
3 |
p.
|
artikel
|
| 69 |
Modulation of Cullin-RING E3 ubiquitin ligase-dependent ubiquitination by small molecule compounds
|
Wu, Kenneth
|
|
|
300 |
3 |
p.
|
artikel
|
| 70 |
Monoubiquitination empowers ubiquitin chain elongation
|
Wu, Kenneth
|
|
|
300 |
3 |
p.
|
artikel
|
| 71 |
Munc18c accelerates SNARE-dependent membrane fusion in the presence of regulatory proteins α-SNAP and NSF
|
Liu, Furong
|
|
|
300 |
3 |
p.
|
artikel
|
| 72 |
NEDD4L intramolecular interactions regulate its auto and substrate NaV1.5 ubiquitination
|
Wright, Katharine M.
|
|
|
300 |
3 |
p.
|
artikel
|
| 73 |
NOP14-mediated ribosome biogenesis is required for mTORC2 activation and predicts rapamycin sensitivity
|
Yan, Xiao
|
|
|
300 |
3 |
p.
|
artikel
|
| 74 |
Nucleic acid hybridization-based detection of pathogenic RNA using microscale thermophoresis
|
Avivi, Matan Yosef
|
|
|
300 |
3 |
p.
|
artikel
|
| 75 |
Oxygen-dependent histone lysine demethylase 4 restricts hepatitis B virus replication
|
Harris, James M.
|
|
|
300 |
3 |
p.
|
artikel
|
| 76 |
Phosphoinositide switches in cell physiology - From molecular mechanisms to disease
|
Lolicato, Fabio
|
|
|
300 |
3 |
p.
|
artikel
|
| 77 |
Pre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks
|
Chen, Linlin
|
|
|
300 |
3 |
p.
|
artikel
|
| 78 |
Protein kinase C signaling “in” and “to” the nucleus: Master kinases in transcriptional regulation
|
Kazanietz, Marcelo G.
|
|
|
300 |
3 |
p.
|
artikel
|
| 79 |
Proteomics, modeling, and fluorescence assays delineate cytochrome b 5 residues involved in binding and stimulation of cytochrome P450 17A1 17,20-lyase
|
Tateishi, Yasuhiro
|
|
|
300 |
3 |
p.
|
artikel
|
| 80 |
Racemization of the substrate and product by serine palmitoyltransferase from Sphingobacterium multivorum yields two enantiomers of the product from d-serine
|
Ikushiro, Hiroko
|
|
|
300 |
3 |
p.
|
artikel
|
| 81 |
RACK1 and IRE1 participate in the translational quality control of amyloid precursor protein in Drosophila models of Alzheimer’s disease
|
Li, Yu
|
|
|
300 |
3 |
p.
|
artikel
|
| 82 |
Rapid reaction studies on the chemistry of flavin oxidation in urocanate reductase
|
Delavari, Niusha
|
|
|
300 |
3 |
p.
|
artikel
|
| 83 |
Rat hepatocytes secrete free oligosaccharides
|
Huang, Chengcheng
|
|
|
300 |
3 |
p.
|
artikel
|
| 84 |
Recovery from desensitization in GluA2 AMPA receptors is affected by a single mutation in the N-terminal domain interface
|
Larsen, Andreas Haahr
|
|
|
300 |
3 |
p.
|
artikel
|
| 85 |
Redox regulation in lifespan determination
|
Karagianni, Christina
|
|
|
300 |
3 |
p.
|
artikel
|
| 86 |
Regulation of calcium entry by cyclic GMP signaling in Toxoplasma gondii
|
Hortua Triana, Miryam A.
|
|
|
300 |
3 |
p.
|
artikel
|
| 87 |
Retinylidene chromophore hydrolysis from mammalian visual and non-visual opsins
|
Hong, John D.
|
|
|
300 |
3 |
p.
|
artikel
|
| 88 |
Rheostats, toggles, and neutrals, Oh my! A new framework for understanding how amino acid changes modulate protein function
|
Swint-Kruse, Liskin
|
|
|
300 |
3 |
p.
|
artikel
|
| 89 |
RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation
|
Demongin, Clément
|
|
|
300 |
3 |
p.
|
artikel
|
| 90 |
ROS in diabetic atria regulate SK2 degradation by Atrogin-1 through the NF-κB signaling pathway
|
Xu, Jian
|
|
|
300 |
3 |
p.
|
artikel
|
| 91 |
SADS-CoV nsp1 inhibits the STAT1 phosphorylation by promoting K11/K48-linked polyubiquitination of JAK1 and blocks the STAT1 acetylation by degrading CBP
|
Xiang, Yingjie
|
|
|
300 |
3 |
p.
|
artikel
|
| 92 |
Satellite double-stranded RNA induces mesenchymal transition in pancreatic cancer by regulating alternative splicing
|
Iwata, Takuma
|
|
|
300 |
3 |
p.
|
artikel
|
| 93 |
Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1
|
Huang, Yen-Hua
|
|
|
300 |
3 |
p.
|
artikel
|
| 94 |
Scs system links copper and redox homeostasis in bacterial pathogens
|
Méndez, Andrea A.E.
|
|
|
300 |
3 |
p.
|
artikel
|
| 95 |
Short peptides based on the conserved regions of MIEN1 protein exhibit anticancer activity by targeting the MIEN1 signaling pathway
|
Tripathi, Amit K.
|
|
|
300 |
3 |
p.
|
artikel
|
| 96 |
Streamlining assays of glycosyltransferases activity using in vitro GT-array (i-GT-ray) platform: Application to family GT37 fucosyltransferases
|
Bhattarai, Matrika
|
|
|
300 |
3 |
p.
|
artikel
|
| 97 |
Structural basis for intra- and intermolecular interactions on RAD9 subunit of 9-1-1 checkpoint clamp implies functional 9-1-1 regulation by RHINO
|
Hara, Kodai
|
|
|
300 |
3 |
p.
|
artikel
|
| 98 |
Structural basis for specific DNA sequence recognition by the transcription factor NFIL3
|
Chen, Sizhuo
|
|
|
300 |
3 |
p.
|
artikel
|
| 99 |
The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis
|
Acevedo, Aracely
|
|
|
300 |
3 |
p.
|
artikel
|
| 100 |
The BHLHE40‒PPM1F‒AMPK pathway regulates energy metabolism and is associated with the aggressiveness of endometrial cancer
|
Asanoma, Kazuo
|
|
|
300 |
3 |
p.
|
artikel
|
| 101 |
The dePARylase NUDT16 promotes radiation resistance of cancer cells by blocking SETD3 for degradation via reversing its ADP-ribosylation
|
Wu, Weijun
|
|
|
300 |
3 |
p.
|
artikel
|
| 102 |
The disordered protein SERF promotes α-Synuclein aggregation through liquid–liquid phase separation
|
Liu, He-Ning
|
|
|
300 |
3 |
p.
|
artikel
|
| 103 |
The E3 ligase SMURF1 stabilizes p27 via UbcH7 catalyzed K29-linked ubiquitin chains to promote cell migration SMURF1-UbcH7 K29 ubiquitination of p27 and cell migration
|
Weinberg, Jasper
|
|
|
300 |
3 |
p.
|
artikel
|
| 104 |
The inhibitor protein IF1 from mammalian mitochondria inhibits ATP hydrolysis but not ATP synthesis by the ATP synthase complex
|
Carroll, Joe
|
|
|
300 |
3 |
p.
|
artikel
|
| 105 |
The P53–P21–RB1 pathway promotes BRD4 degradation in liver cancer through USP1
|
Li, Neng
|
|
|
300 |
3 |
p.
|
artikel
|
| 106 |
The role of O-GlcNAcylation in RNA polymerase II transcription
|
Lewis, Brian A.
|
|
|
300 |
3 |
p.
|
artikel
|
| 107 |
The role of RNF138 in DNA end resection is regulated by ubiquitylation and CDK phosphorylation
|
Locke, Andrew J.
|
|
|
300 |
3 |
p.
|
artikel
|
| 108 |
The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase
|
Sakuragi, Takaharu
|
|
|
300 |
3 |
p.
|
artikel
|
| 109 |
The RsfSR two-component system regulates SigF function by monitoring the state of the respiratory electron transport chain in Mycobacterium smegmatis
|
Oh, Yuna
|
|
|
300 |
3 |
p.
|
artikel
|
| 110 |
The SET7 protein of Leishmania donovani moderates the parasite’s response to a hostile oxidative environment
|
Pal, Jyoti
|
|
|
300 |
3 |
p.
|
artikel
|
| 111 |
The splicing factor Prpf31 is required for hematopoietic stem and progenitor cell expansion during zebrafish embryogenesis
|
Lv, Yuexia
|
|
|
300 |
3 |
p.
|
artikel
|
| 112 |
Transcription elongation mechanisms of RNA polymerases I, II, and III and their therapeutic implications
|
Jacobs, Ruth Q.
|
|
|
300 |
3 |
p.
|
artikel
|
| 113 |
Trp207 regulation of voltage-dependent activation of human Hv1 proton channel
|
Zhang, Lu
|
|
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300 |
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