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                             105 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A brain specific alternatively spliced isoform of nonmuscle myosin IIA lacks its mechanoenzymatic activities Das, Samprita

299 9 p.
artikel
2 Acetylation of aldehyde dehydrogenase ALDH1L2 regulates cellular redox balance and the chemosensitivity of colorectal cancer to 5-fluorouracil Li, Chaoqun

299 9 p.
artikel
3 Acidosis attenuates CPT-I-supported bioenergetics as a potential mechanism limiting lipid oxidation Frangos, Sara M.

299 9 p.
artikel
4 A conserved arginine within the αC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities Soudah, Nadine

299 9 p.
artikel
5 Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain Clark, Nathaniel E.

299 9 p.
artikel
6 A detailed kinetic model of glycolysis in Plasmodium falciparum-infected red blood cells for antimalarial drug target identification van Niekerk, David D.

299 9 p.
artikel
7 A half century of exploring DNA excision repair in chromatin Smerdon, Michael J.

299 9 p.
artikel
8 Alkaline intracellular pH (pHi) increases PI3K activity to promote mTORC1 and mTORC2 signaling and function during growth factor limitation Kazyken, Dubek

299 9 p.
artikel
9 ALKBH4 is a novel enzyme that promotes translation through modified uridine regulation Kogaki, Takahiro

299 9 p.
artikel
10 Allopurinol and oxypurinol differ in their strength and mechanisms of inhibition of xanthine oxidoreductase Sekine, Mai

299 9 p.
artikel
11 Allosteric modulation of cytochrome P450 enzymes by the NADPH cytochrome P450 reductase FMN-containing domain Burris-Hiday, Sarah D.

299 9 p.
artikel
12 Alternative splicing regulates adaptor protein binding, trafficking, and activity of the Vps10p domain receptor SorCS2 in neuronal development Skeldal, Sune

299 9 p.
artikel
13 An ependymin-related blue carotenoprotein decorates marine blue sponge Kawasaki, Shinji

299 9 p.
artikel
14 A novel class of xylanases specifically degrade marine red algal β1,3/1,4-mixed-linkage xylan Zhao, Fang

299 9 p.
artikel
15 An unstructured proteasome inhibitor comes into focus Nemec, Antonia A.

299 9 p.
artikel
16 A riboside hydrolase that salvages both nucleobases and nicotinamide in the auxotrophic parasite Trichomonas vaginalis Patrone, Marco

299 9 p.
artikel
17 Assessment of the roles of Spt5-nucleic acid contacts in promoter proximal pausing of RNA polymerase II Dollinger, Roberta

299 9 p.
artikel
18 Beta-subunit-eliminated eHAP expression (BeHAPe) cells reveal subunit regulation of the cardiac voltage-gated sodium channel Minard, Annabel Y.

299 9 p.
artikel
19 Biochemical functions and structure of Caenorhabditis elegans ZK177.8 protein: Aicardi–Goutières syndrome SAMHD1 dNTPase ortholog Maehigashi, Tatsuya

299 9 p.
artikel
20 Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth Nagai, Kenichiro

299 9 p.
artikel
21 CARM1 arginine methyltransferase as a therapeutic target for cancer Santos, Margarida

299 9 p.
artikel
22 Cas4/1 dual nuclease activities enable prespacer maturation and directional integration in a type I-G CRISPR-Cas system Dhingra, Yukti

299 9 p.
artikel
23 Cell type–specific labeling of newly synthesized proteins by puromycin inactivation Cabrera-Cabrera, Florencia

299 9 p.
artikel
24 Characterization of a novel inhibitor for the New Delhi metallo-β-lactamase-4: Implications for drug design and combating bacterial drug resistance Thoden, James B.

299 9 p.
artikel
25 Chlorotoxin binds to both matrix metalloproteinase 2 and neuropilin 1 Farkas, Sándor

299 9 p.
artikel
26 Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction Pellegrini, Hannah

299 9 p.
artikel
27 Colorectal cancer-associated mutations impair EphB1 kinase function Kim, Yunyoung

299 9 p.
artikel
28 Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells Tian, Ya-Min

299 9 p.
artikel
29 Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome Nůsková, Hana

299 9 p.
artikel
30 Cooperation of long noncoding RNA LOC100909675 and transcriptional regulator CTCF modulates Cdk1 transcript to control astrocyte proliferation Wu, Ronghua

299 9 p.
artikel
31 Coping with stress: How bacteria fine-tune protein synthesis and protein transport Njenga, Robert

299 9 p.
artikel
32 Cover
299 9 p.
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33 C-terminal sequence stability profiling in Saccharomyces cerevisiae reveals protective protein quality control pathways Hasenjäger, Sophia

299 9 p.
artikel
34 Deep annotation of long noncoding RNAs by assembling RNA-seq and small RNA-seq data Zhang, Jiaming

299 9 p.
artikel
35 1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding Hamid, Rawia

299 9 p.
artikel
36 Development of a versatile LCM-Seq method for spatial transcriptomics of fluorescently tagged cholinergic neuron populations Rumpler, Éva

299 9 p.
artikel
37 Development of a V5-tag–directed nanobody and its implementation as an intracellular biosensor of GPCR signaling Zeghal, Manel

299 9 p.
artikel
38 Diverse p120RasGAP interactions with doubly phosphorylated partners EphB4, p190RhoGAP, and Dok1 Vish, Kimberly J.

299 9 p.
artikel
39 Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation Slepak, Tatiana I.

299 9 p.
artikel
40 Dynamic players and intricate interactions: An integrated investigation of the Mla lipid transport system Ng, Dixon

299 9 p.
artikel
41 Effect of mRNA/tRNA mutations on translation speed: Implications for human diseases Davyt, Marcos

299 9 p.
artikel
42 Efficient NADPH-dependent dehalogenation afforded by a self-sufficient reductive dehalogenase Fisher, Karl

299 9 p.
artikel
43 eIF3i promotes colorectal cancer cell survival via augmenting PHGDH translation Zhang, Yaguang

299 9 p.
artikel
44 Epstein–Barr virus microRNA miR-BART2-5p accelerates nasopharyngeal carcinoma metastasis by suppressing RNase Ⅲ endonuclease DICER1 Wu, Yangge

299 9 p.
artikel
45 ER stress decreases exosome production through adiponectin/T-cadherin-dependent and -independent pathways Fukuoka, Keita

299 9 p.
artikel
46 FDX1 regulates cellular protein lipoylation through direct binding to LIAS Dreishpoon, Margaret B.

299 9 p.
artikel
47 Flanking regions, amyloid cores, and polymorphism: the potential interplay underlying structural diversity Bhopatkar, Anukool A.

299 9 p.
artikel
48 Flipons and small RNAs accentuate the asymmetries of pervasive transcription by the reset and sequence-specific microcoding of promoter conformation Herbert, Alan

299 9 p.
artikel
49 G-quadruplex in hepatitis B virus pregenomic RNA promotes its translation Wang, Jingjing

299 9 p.
artikel
50 Histidine Nτ-methylation identified as a new posttranslational modification in histone H2A at His-82 and H3 at His-39 Hayashi, Takahiro

299 9 p.
artikel
51 Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy Hussain, Mansoor

299 9 p.
artikel
52 Identification of antimycin A as a c-Myc degradation accelerator via high-throughput screening Liu, Ziyu

299 9 p.
artikel
53 Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis) Sharma, Bhesh Raj

299 9 p.
artikel
54 Increased intracellular persulfide levels attenuate HlyU-mediated hemolysin transcriptional activation in Vibrio cholerae Pis Diez, Cristian M.

299 9 p.
artikel
55 Increased Phospholipid Flux Bypasses Overlapping Essential Requirements for the Yeast Sac1p Phosphoinositide Phosphatase and ER-PM Membrane Contact Sites Nenadic, Aleksa

299 9 p.
artikel
56 Inhibition of Ezh2 redistributes bivalent domains within transcriptional regulators associated with WNT and Hedgehog pathways in osteoblasts Carrasco, Margarita E.

299 9 p.
artikel
57 Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding Sevrioukova, Irina F.

299 9 p.
artikel
58 Intermolecular electron transfer in radical SAM enzymes as a new paradigm for reductive activation Eastman, Karsten A.S.

299 9 p.
artikel
59 Intracellular energy production and distribution in hypoxia Flood, Darragh

299 9 p.
artikel
60 Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production Zhang, Chun-Xue

299 9 p.
artikel
61 Lipoylation is dependent on the ferredoxin FDX1 and dispensable under hypoxia in human cells Joshi, Pallavi R.

299 9 p.
artikel
62 Long-chain dicarboxylic acids play a critical role in inducing peroxisomal β-oxidation and hepatic triacylglycerol accumulation Zhang, Wei

299 9 p.
artikel
63 Maintenance of cellular vitamin B6 levels and mitochondrial oxidative function depend on pyridoxal 5′-phosphate homeostasis protein Ciapaite, Jolita

299 9 p.
artikel
64 Mammalian neurotoxins, Blarina paralytic peptides, cause hyperpolarization of human T-type Ca channel hCav3.2 activation Yano, Yusuke

299 9 p.
artikel
65 MAPK13 stabilization via m6A mRNA modification limits anticancer efficacy of rapamycin Kim, Joohwan

299 9 p.
artikel
66 Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex Elkholi, Islam E.

299 9 p.
artikel
67 Methionine sulfoxide reductases and cholesterol transporter STARD3 constitute an efficient system for detoxification of cholesterol hydroperoxides Lim, Jung Mi

299 9 p.
artikel
68 Microtubule-associated septin complexes modulate kinesin and dynein motility with differential specificities Suber, Yani

299 9 p.
artikel
69 Mitochondrial double-stranded RNA triggers induction of the antiviral DNA deaminase APOBEC3A and nuclear DNA damage Wick, Chloe

299 9 p.
artikel
70 Molecular dynamics simulations support a multistep pathway for activation of branched actin filament nucleation by Arp2/3 complex Singh, Yuvraj

299 9 p.
artikel
71 Molecular insights into GPCR mechanisms for drugs of abuse Sanchez-Reyes, Omar B.

299 9 p.
artikel
72 MYB regulates the SUMO protease SENP1 and its novel interaction partner UXT, modulating MYB target genes and the SUMO landscape Lemma, Roza Berhanu

299 9 p.
artikel
73 N-acetylmuramic acid recognition by MurK kinase from the MurNAc auxotrophic oral pathogen Tannerella forsythia Stasiak, Aleksandra Cecylia

299 9 p.
artikel
74 New insights into RNA processing by the eukaryotic tRNA splicing endonuclease Hayne, Cassandra K.

299 9 p.
artikel
75 N-glycosylation is a potent regulator of prion protein neurotoxicity Schilling, Kevin M.

299 9 p.
artikel
76 Novel pneumococcal capsule type 33E results from the inactivation of glycosyltransferase WciE in vaccine type 33F Ganaie, Feroze A.

299 9 p.
artikel
77 PARP14 is a writer, reader, and eraser of mono-ADP-ribosylation Torretta, Archimede

299 9 p.
artikel
78 Phospholipid tail asymmetry allows cellular adaptation to anoxic environments Panconi, Luca

299 9 p.
artikel
79 Polycomb proteins translate histone methylation to chromatin folding Lizana, Ludvig

299 9 p.
artikel
80 Quantitative proteomics and phosphoproteomics of PP2A-PPP2R5D variants reveal deregulation of RPS6 phosphorylation via converging signaling cascades Smolen, Kali A.

299 9 p.
artikel
81 rhFGF-21 accelerates corneal epithelial wound healing through the attenuation of oxidative stress and inflammatory mediators in diabetic mice Li, Le

299 9 p.
artikel
82 Sequence-specific targeting of Caenorhabditis elegans C-Ala to the D-loop of tRNAAla Antika, Titi Rindi

299 9 p.
artikel
83 ShlA toxin of Serratia induces P2Y2- and α5β1-dependent autophagy and bacterial clearance from host cells Tuttobene, Marisel R.

299 9 p.
artikel
84 SHP-1 phosphatase acts as a coactivator of PCK1 transcription to control gluconeogenesis Kumar, Amit

299 9 p.
artikel
85 Single-molecule analysis reveals that a glucagon-bound extracellular domain of the glucagon receptor is dynamic Liu, Ting

299 9 p.
artikel
86 Solution structure of the HOIL-1L NZF domain reveals a conformational switch regulating linear ubiquitin affinity Walinda, Erik

299 9 p.
artikel
87 Sphingomyelin synthase–related protein SMSr is a phosphatidylethanolamine phospholipase C that promotes nonalcoholic fatty liver disease Chiang, Yeun-po

299 9 p.
artikel
88 ssDNA reeling is an intermediate step in the reiterative DNA unwinding activity of the WRN-1 helicase Le, Son Truong

299 9 p.
artikel
89 Structural insight into G-protein chaperone-mediated maturation of a bacterial adenosylcobalamin-dependent mutase Vaccaro, Francesca A.

299 9 p.
artikel
90 Structure of the Hepatitis B virus capsid quasi-6-fold with a trapped C-terminal domain reveals capsid movements associated with domain exit Kim, Christine

299 9 p.
artikel
91 SUZ domain–containing proteins have multiple effects on nonsense-mediated decay target transcripts Halbout, Mathias

299 9 p.
artikel
92 α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices Vargas, Karina J.

299 9 p.
artikel
93 Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth Valenciano-Bellido, Sandra

299 9 p.
artikel
94 Termination codon readthrough of NNAT mRNA regulates calcium-mediated neuronal differentiation Pandit, Madhuparna

299 9 p.
artikel
95 The adenylate cyclase toxin RTX domain follows a series templated folding mechanism with implications for toxin activity Chen, Guojun

299 9 p.
artikel
96 The “life-span” of lytic polysaccharide monooxygenases (LPMOs) correlates to the number of turnovers in the reductant peroxidase reaction Kuusk, Silja

299 9 p.
artikel
97 The mRNA binding-mediated self-regulatory function of small heat shock protein IbpA in γ-proteobacteria is conferred by a conserved arginine Cheng, Yajie

299 9 p.
artikel
98 The PARN, TOE1, and USB1 RNA deadenylases and their roles in non-coding RNA regulation Huynh, Thao Ngoc

299 9 p.
artikel
99 The psychosis risk factor RBM12 encodes a novel repressor of GPCR/cAMP signal transduction Semesta, Khairunnisa M.

299 9 p.
artikel
100 The role of PMP22 T118M in Charcot–Marie–Tooth disease remains unsolved Record, Christopher J.

299 9 p.
artikel
101 The transcription factor ChREBP links mitochondrial lipidomes to mitochondrial morphology and progression of diabetic kidney disease Li, Li

299 9 p.
artikel
102 TMEM2 is a bona fide hyaluronidase possessing intrinsic catalytic activity Narita, Takuma

299 9 p.
artikel
103 Transient conformations in the unliganded FK506 binding domain of FKBP51 correspond to two distinct inhibitor-bound states Anderson, Janet S.

299 9 p.
artikel
104 Withdrawal: Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts Gilkes, Daniele M.

299 9 p.
artikel
105 ZBTB40 is a telomere-associated protein and protects telomeres in human ALT cells Zhou, Mingqing

299 9 p.
artikel
                             105 gevonden resultaten
 
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