Digitale Bibliotheek
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                             135 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 Accelerated export of Dicer1 from lipid-challenged hepatocytes buffers cellular miRNA-122 levels and prevents cell death Bandyopadhyay, Diptankar

299 8 p.
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2 A conserved 3D pattern in a Streptococcus pyogenes M protein immunogen elicits M-type crossreactivity Wang, Kuei-Chen

299 8 p.
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3 A conserved tryptophan in the acylated segment of RTX toxins controls their β2 integrin–independent cell penetration Osickova, Adriana

299 8 p.
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4 A crystallin mutant cataract with mineral deposits Minogue, Peter J.

299 8 p.
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5 A formamidopyrimidine derivative from the deoxyguanosine adduct produced by food contaminant acrylamide induces DNA replication block and mutagenesis Akagi, Jun-ichi

299 8 p.
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6 Amphetamine-induced reverse transport of dopamine does not require cytosolic Ca2+ Støier, Jonatan Fullerton

299 8 p.
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7 Androgen receptor transcriptional activity is required for heregulin-1β–mediated nuclear localization of the HER3/ErbB3 receptor tyrosine kinase Jathal, Maitreyee K.

299 8 p.
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8 An efficient selenium transport pathway of selenoprotein P utilizing a high-affinity ApoER2 receptor variant and being independent of selenocysteine lyase Mizuno, Ayako

299 8 p.
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9 An engineered cell line with a hRpn1-attached handle to isolate proteasomes Negi, Hitendra

299 8 p.
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10 An insulin-regulated arrestin domain protein controls hepatic glucagon action Dagdeviren, Sezin

299 8 p.
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11 Arabidopsis translation initiation factor binding protein CBE1 negatively regulates accumulation of the NADPH oxidase respiratory burst oxidase homolog D George, Jeoffrey

299 8 p.
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12 A role for microsomal glutathione transferase 1 in melanin biosynthesis and melanoma progression Zhang, Jie

299 8 p.
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13 Arsenite oxidase in complex with antimonite and arsenite oxyanions: Insights into the catalytic mechanism Engrola, Filipa

299 8 p.
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14 Assembly dynamics and structure of an aegerolysin, ostreolysin A6 Yilmaz, Neval

299 8 p.
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15 Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga Zhou, Jujun

299 8 p.
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16 Cataract-causing Y204X mutation of crystallin protein CRYβB1 promotes its C-terminal degradation and higher-order oligomerization Jing, Xuping

299 8 p.
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17 Characterization of a novel cysteine-less Cu/Zn-superoxide dismutase in Paenibacillus lautus missing a conserved disulfide bond Furukawa, Yoshiaki

299 8 p.
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18 Coenzyme biosynthesis in response to precursor availability reveals incorporation of β-alanine from pantothenate in prototrophic bacteria Ryback, Birgitta

299 8 p.
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19 Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators Cato, Michael L.

299 8 p.
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20 Computational redesign of cytochrome P450 CYP102A1 for highly stereoselective omeprazole hydroxylation by UniDesign Huang, Xiaoqiang

299 8 p.
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21 Conformational dynamics of complement protease C1r inhibitor proteins from Lyme disease– and relapsing fever–causing spirochetes Roy, Sourav

299 8 p.
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22 Correction: Crystal structures of protein glutaminase and its pro forms converted into enzyme-substrate complex Hashizume, Ryota

299 8 p.
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23 Correction: Mutational and biophysical analyses reveal a TFIIIC binding region in the TFIIF-related Rpc53 subunit of RNA polymerase III Chandra Shekhar, Arvind

299 8 p.
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24 Correction: Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications Terradas, Anna Lechado

299 8 p.
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25 Correction: Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2 Mishra, Nitin

299 8 p.
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26 Correction: Understanding the physical basis of memory: Molecular mechanisms of the engram San Luis, Clara Ortega-de

299 8 p.
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27 Cover
299 8 p.
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28 Cycloartenyl ferulate improves natural killer (NK) cell immunity against cancer by binding to IFNγ receptor 1 Li, Mingfeng

299 8 p.
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29 Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia St-Louis, Johanna L.

299 8 p.
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30 Deubiquitinase USP9X stabilizes RNA m6A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival Wang, Peipei

299 8 p.
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31 Developmental Pb exposure increases AD risk via altered intracellular Ca2+ homeostasis in hiPSC-derived cortical neurons Xie, Junkai

299 8 p.
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32 Development of in-line anoxic small-angle X-ray scattering and structural characterization of an oxygen-sensing transcriptional regulator Illava, Gabrielle

299 8 p.
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33 Different conformational dynamics of SNARE protein Ykt6 among yeast and mammals Ji, Jie

299 8 p.
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34 Differential roles for ACBD4 and ACBD5 in peroxisome–ER interactions and lipid metabolism Costello, Joseph L.

299 8 p.
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35 Differential sensitivity of the yeast Lon protease Pim1p to impaired mitochondrial respiration Metzger, Meredith B.

299 8 p.
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36 Different tau fibril types reduce prion level in chronically and de novo infected cells Celauro, Luigi

299 8 p.
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37 Direct interaction between fd phage pilot protein pIII and the TolQ–TolR proton-dependent motor provides new insights into the import of filamentous phages Pellegri, Callypso

299 8 p.
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38 Disruption of sirtuin 7 in zebrafish facilitates hypoxia tolerance Liao, Qian

299 8 p.
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39 Divergent roles of estrogen receptor subtypes in regulating estrogen-modulated colonic ion transports and epithelial repair Wan, Hanxing

299 8 p.
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40 Diversity of function and higher-order structure within HWE sensor histidine kinases Dikiy, Igor

299 8 p.
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41 Drosophila class-I myosins that can impact left-right asymmetry have distinct ATPase kinetics Báez-Cruz, Faviolla A.

299 8 p.
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42 ER stress increases expression of intracellular calcium channel RyR1 to modify Ca2+ homeostasis in pancreatic beta cells Zhang, Irina X.

299 8 p.
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43 Evidence for direct interaction between the oncogenic proteins E6 and E7 of high-risk human papillomavirus (HPV) Lim, JiaWen

299 8 p.
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44 Expression conditions and characterization of a novelly constructed lipoprotein intended as a vaccine to prevent human Haemophilus influenzae infections Kaur, Ravinder

299 8 p.
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45 Extracellular vimentin is sufficient to promote cell attachment, spreading, and motility by a mechanism involving N-acetyl glucosamine-containing structures Bucki, Robert

299 8 p.
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46 Focal-adhesion kinase regulates the sialylation of N-glycans via the PI4KIIα-PI4P pathway Sun, Yuhan

299 8 p.
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47 Follicular cells protect Xenopus oocyte from abnormal maturation via integrin signaling downregulation and O-GlcNAcylation control Martoriati, Alain

299 8 p.
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48 Functional analysis of the protocatechuate branch of the β-ketoadipate pathway in Aspergillus niger Sgro, Michael

299 8 p.
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49 Generative artificial intelligence in Journal of Biological Chemistry Colbran, Roger J.

299 8 p.
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50 Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis Cooke, Mariana

299 8 p.
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51 Glucose controls manganese homeostasis through transcription factors regulating known and newly identified manganese transporter genes in Bacillus subtilis Ogura, Mitsuo

299 8 p.
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52 Heme binding to the SARS-CoV-2 spike glycoprotein Freeman, Samuel L.

299 8 p.
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53 Hepatic protein kinase Cbeta deficiency mitigates late-onset obesity Shu, Yaoling

299 8 p.
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54 High-affinity CD8 variants enhance the sensitivity of pMHCI antigen recognition via low-affinity TCRs Knezevic, Lea

299 8 p.
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55 Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate Liu, Jinghan

299 8 p.
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56 Identification and characterization of aptameric inhibitors of human neutrophil elastase Malicki, Stanisław

299 8 p.
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57 Identification of the glycosylphosphatidylinositol-specific phospholipase A2 (GPI-PLA2) that mediates GPI fatty acid remodeling in Trypanosoma bruce i Ji, Zhe

299 8 p.
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58 Inhibition of cleavage of human complement component C5 and the R885H C5 variant by two distinct high affinity anti-C5 nanobodies Struijf, Eva M.

299 8 p.
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59 Interactions between Fkh1 monomers stabilize its binding to DNA replication origins Reinapae, Allan

299 8 p.
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60 Interferon at the crossroads of SARS-CoV-2 infection and COVID-19 disease Samuel, Charles E.

299 8 p.
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61 In vivo and in vitro characterizations of melibiose permease (MelB) conformation-dependent nanobodies reveal sugar-binding mechanisms Katsube, Satoshi

299 8 p.
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62 Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model Ohkawa, Yuki

299 8 p.
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63 Isethionate is an intermediate in the degradation of sulfoacetate by the human gut pathobiont Bilophila wadsworthia Liu, Xumei

299 8 p.
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64 ISL1 regulates lung branching morphogenesis via Shh signaling pathway Huang, Ruiqi

299 8 p.
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65 Kinetic and structural characterization of carboxyspermidine dehydrogenase of polyamine biosynthesis Lee, Danielle F.

299 8 p.
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66 Lack of polyamines leads to cotranslational degradation of the general stress factor RpoS in Escherichia coli Majdalani, Nadim

299 8 p.
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67 Lipid biosynthesis perturbation impairs endoplasmic reticulum–associated degradation Turk, Samantha M.

299 8 p.
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68 Localized Leishmania major infection disrupts systemic iron homeostasis that can be controlled by oral iron supplementation Banerjee, Sourav

299 8 p.
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69 Mammalian type opsin 5 preferentially activates G14 in Gq-type G proteins triggering intracellular calcium response Sato, Keita

299 8 p.
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70 Mechanisms controlling membrane recruitment and activation of the autoinhibited SHIP1 inositol 5-phosphatase Waddell, Grace L.

299 8 p.
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71 Membrane structure and internalization dynamics of human Flower isoforms hFWE3 and hFWE4 indicate a conserved endocytic role for hFWE4 Rudd, Justin C.

299 8 p.
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72 Metal-ion transporter SLC39A8 is required for brain manganese uptake and accumulation Liu, Qingli

299 8 p.
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73 Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells Lin, Yiqi Christina

299 8 p.
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74 Molecular dynamics simulations reveal the hidden EF-hand of EF-SAM as a possible key thermal sensor for STIM1 activation by temperature Neamtu, Andrei

299 8 p.
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75 Monocyte adhesive hyaluronan matrix induced by hyperglycemia in diabetic lung injuries Wang, Andrew Jun

299 8 p.
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76 Multiple Mycobacterium abscessus O-acetyltransferases influence glycopeptidolipid structure and colony morphotype Illouz, Morgane

299 8 p.
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77 NAD metabolism modulates inflammation and mitochondria function in diabetic kidney disease Myakala, Komuraiah

299 8 p.
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78 Nei-like DNA glycosylase 2 selectively antagonizes interferon-β expression upon respiratory syncytial virus infection Pan, Lang

299 8 p.
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79 Neofunctionalization of S-adenosylmethionine decarboxylase into pyruvoyl-dependent L-ornithine and L-arginine decarboxylases is widespread in bacteria and archaea Li, Bin

299 8 p.
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80 Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation O’Neill, Audrey G.

299 8 p.
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81 New insights on the photocomplex of Roseiflexus castenholzii revealed from comparisons of native and carotenoid-depleted complexes Qi, Chen-Hui

299 8 p.
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82 Nicotinamide N-methyltransferase mediates lipofibroblast–myofibroblast transition and apoptosis resistance Rehan, Mohammad

299 8 p.
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83 NPC1 plays a role in the trafficking of specific cargo to melanosomes Rus, Alina Adriana

299 8 p.
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84 N-terminal intrinsic disorder is an ancestral feature of Gγ subunits that influences the balance between different Gβγ signaling axes in yeast Su, Xinya

299 8 p.
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85 On-demand utilization of phosphoribosyl pyrophosphate by downstream anabolic pathways Pinson, Benoît

299 8 p.
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86 PABPN1 aggregation is driven by Ala expansion and poly(A)-RNA binding, leading to CFIm25 sequestration that impairs alternative polyadenylation Guan, Wen-Liang

299 8 p.
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87 PAF49: An RNA Polymerase I subunit essential for rDNA transcription and stabilization of PAF53 McNamar, Rachel

299 8 p.
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88 Palmitoylation-dependent control of JAK1 kinase signaling governs responses to neuropoietic cytokines and survival in DRG neurons Hernandez, Luiselys M.

299 8 p.
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89 Pathogenic Aβ production by heterozygous PSEN1 mutations is intrinsic to the mutant protein and not mediated by conformational hindrance of wild-type PSEN1 Kurth, Vanessa

299 8 p.
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90 PC4-mediated Ku complex PARylation facilitates NHEJ-dependent DNA damage repair Pan, Qimei

299 8 p.
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91 Persistent ER stress causes GPI anchor deficit to convert a GPI-anchored prion protein into pro-PrP via the ATF6–miR449c-5p–PIGV axis Li, JingFeng

299 8 p.
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92 PE-STOP: A versatile tool for installing nonsense substitutions amenable for precise reversion Song, Ziguo

299 8 p.
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93 Phosphatases maintain low catalytic activity of SGK1: DNA damage resets the balance in favor of phosphorylation Gu, Wenxue

299 8 p.
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94 Phosphatidate phosphatase Pah1 contains a novel RP domain that regulates its phosphorylation and function in yeast lipid synthesis Stukey, Geordan J.

299 8 p.
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95 Phosphoregulation of DNA repair via the Rad51 auxiliary factor Swi5–Sfr1 Liang, Pengtao

299 8 p.
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96 Photocycle alteration and increased enzymatic activity in genetically modified photoactivated adenylate cyclase OaPAC Raics, Katalin

299 8 p.
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97 Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63 Li, Qiuling

299 8 p.
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98 Protein–protein interactions between tenascin-R and RPTPζ/phosphacan are critical to maintain the architecture of perineuronal nets Sinha, Ashis

299 8 p.
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99 PTBP1 suppresses porcine epidemic diarrhea virus replication via inducing protein degradation and IFN production Qin, Wenzhen

299 8 p.
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100 Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance Feng, Wei

299 8 p.
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101 REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice Sunilkumar, Siddharth

299 8 p.
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102 Repair of topoisomerase 1–induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding Shimizu, Naoto

299 8 p.
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103 Respiratory complex I in mitochondrial membrane catalyzes oversized ubiquinones Ikunishi, Ryo

299 8 p.
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104 Rpb7 represses transcription-coupled nucleotide excision repair Gong, Wenzhi

299 8 p.
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105 SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells Kim, Ik-Jung

299 8 p.
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106 Simultaneous isolation of hormone receptor–positive breast cancer organoids and fibroblasts reveals stroma-mediated resistance mechanisms Hogstrom, Jenny M.

299 8 p.
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107 Single amino acid–based PROTACs trigger degradation of the oncogenic kinase BCR–ABL in chronic myeloid leukemia (CML) Zhang, Jianchao

299 8 p.
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108 Spontaneous histone exchange between nucleosomes Das, Subhra Kanti

299 8 p.
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109 Stress-induced pseudokinase TRB3 augments IL1β signaling by interacting with Flightless homolog 1 Gonuguntla, Sumati

299 8 p.
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110 Striatal mGlu5-mediated synaptic plasticity is independently regulated by location-specific receptor pools and divergent signaling pathways Jong, Yuh-Jiin I.

299 8 p.
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111 Structural and molecular basis for urea recognition by Prochlorococcus Wang, Chen

299 8 p.
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112 Structural and spectroscopic characterization of RufO indicates a new biological role in rufomycin biosynthesis Jordan, Stephanie

299 8 p.
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113 Structural basis of bidirectional allostery across the heme in a cytochrome P450 enzyme Kumar, Amit

299 8 p.
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114 Structural displacement model of chitooligosaccharide transport through chitoporin Sanram, Surapoj

299 8 p.
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115 Structure and function of a dual antagonist of the human growth hormone and prolactin receptors with site-specific PEG conjugates Basu, Reetobrata

299 8 p.
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116 SVCT2/SLC23A2 is a sodium-dependent urate transporter: functional properties and practical application Toyoda, Yu

299 8 p.
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117 Synthetic receptor platform to identify loss-of-function single nucleotide variants and designed mutants in the death receptor Fas/CD95 Minafra, Anna Rita

299 8 p.
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118 The battle for silver binding: How the interplay between the SilE, SilF, and SilB proteins contributes to the silver efflux pump mechanism Arrault, Cyrielle

299 8 p.
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119 The bromo-adjacent homology domains of PBRM1 associate with histone tails and contribute to PBAF-mediated gene regulation Petell, Christopher J.

299 8 p.
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120 The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase–LRP4 receptor complex by agrin at the neuromuscular junction Uyen Dao, Thi Minh

299 8 p.
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121 The disordered C terminus of ALKBH5 promotes phase separation and paraspeckles assembly Qin, Xiaoyang

299 8 p.
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122 The diverse structural modes of tRNA binding and recognition Biela, Anna

299 8 p.
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123 The FSH–mTOR–CNP signaling axis initiates follicular antrum formation by regulating tight junction, ion pumps, and aquaporins Wang, Xiaodong

299 8 p.
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124 The peroxidation-derived DNA adduct, 6-oxo-M1dG, is a strong block to replication by human DNA polymerase η Richie-Jannetta, Robyn

299 8 p.
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125 The Pros of changing tRNA identity Ibba, Michael

299 8 p.
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126 The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts Kases, Katharina

299 8 p.
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127 The translation initiating factor eIF4E and arginine methylation underlie G3BP1 function in dendritic spine development of neurons Dong, Rui

299 8 p.
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128 Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease Kim, Young-Chae

299 8 p.
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129 Trapping and retaining intermediates in glycosyltransferases Guerin, Marcelo E.

299 8 p.
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130 Trophoblast cell surface antigen-2 phosphorylation triggered by binding of galectin-3 drives metastasis through down-regulation of E-cadherin Iwamoto, Shungo

299 8 p.
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131 UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair Lee, Seong-Ok

299 8 p.
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132 Unveiling the human nitroproteome: Protein tyrosine nitration in cell signaling and cancer Griswold-Prenner, Irene

299 8 p.
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133 Vascular endothelial profilin-1 drives a protumorigenic tumor microenvironment and tumor progression in renal cancer Gau, David

299 8 p.
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134 Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages Bowen, Nicole E.

299 8 p.
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135 Withdrawal: Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia Zhang, Huafeng

299 8 p.
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                             135 gevonden resultaten
 
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