Digitale Bibliotheek
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                             124 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A conventional PKC critical for both the light-dependent and the light-independent regulation of the actin cytoskeleton in Drosophila photoreceptors Shieh, Bih-Hwa

299 6 p.
artikel
2 A CsoR family transcriptional regulator, TTHA1953, controls the sulfur oxidation pathway in Thermus thermophilus HB8 Barrows, John K.

299 6 p.
artikel
3 AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity Ruiz, Mario

299 6 p.
artikel
4 A DNAzyme-enhanced nonlinear hybridization chain reaction for sensitive detection of microRNA Cao, Xiuen

299 6 p.
artikel
5 Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin2 G protein–coupled receptor Babin, Katie M.

299 6 p.
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6 Adverse cardiac remodeling augments adipose tissue ß-adrenergic signaling and lipolysis counteracting diet-induced obesity Kolleritsch, Stephanie

299 6 p.
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7 A heme pocket aromatic quadrupole modulates gas binding to cytochrome c′-β: Implications for NO sensors Adams, Hannah R.

299 6 p.
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8 A high fat diet fosters elevated bisretinoids Kim, Hye Jin

299 6 p.
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9 An evolving view of complex II—noncanonical complexes, megacomplexes, respiration, signaling, and beyond Iverson, T.M.

299 6 p.
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10 A novel BRET-based assay to investigate binding and residence time of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells Cunha, Micael R.

299 6 p.
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11 Antibody toolkit to investigate eEF1A methylation dynamics in mRNA translation elongation Mealey-Farr, Robert

299 6 p.
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12 Arabidopsis nicotianamine synthases comprise a common core-NAS domain fused to a variable autoinhibitory C terminus Seebach, Hiroyuki

299 6 p.
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13 A selective nonpeptide somatostatin receptor 5 agonist effectively decreases insulin secretion in hyperinsulinism Juliana, Christine A.

299 6 p.
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14 Assembly properties of bacterial actin MreB involved in Spiroplasma swimming motility Takahashi, Daichi

299 6 p.
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15 Augmin is a Ran-regulated spindle assembly factor Kraus, Jodi

299 6 p.
artikel
16 A vital role for PICK1 in the differential regulation of metabotropic glutamate receptor internalization and synaptic AMPA receptor endocytosis Ramsakha, Namrata

299 6 p.
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17 A web-based integrative transcriptome analysis, RNAseqChef, uncovers the cell/tissue type-dependent action of sulforaphane Etoh, Kan

299 6 p.
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18 Ceramide analog C2-cer induces a loss in insulin sensitivity in muscle cells through the salvage/recycling pathway Bandet, Cécile L.

299 6 p.
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19 Characterization of the cholesterol biosynthetic pathway in Dioscorea transversa Salisbury, Lauren J.

299 6 p.
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20 Comparative three-dimensional genome architectures of adipose tissues provide insight into human-specific regulation of metabolic homeostasis Liu, Pengliang

299 6 p.
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21 Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage Moody, James D.

299 6 p.
artikel
22 Conformational changes in protein kinase A along its activation cycle are rooted in the folding energetics of cyclic-nucleotide binding domains Chau, Amy K.

299 6 p.
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23 Construction and validation of customized genomes for human and mouse ribosomal DNA mapping George, Subin S.

299 6 p.
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24 Coordination between the Ndc80 complex and dynein is essential for microtubule plus-end capture by kinetochores during early mitosis Amin, Mohammed Abdullahel

299 6 p.
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25 Correction: N-glycosylation modulates enzymatic activity of Trypanosoma congolense trans-sialidase Rosenau, Jana

299 6 p.
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26 Cover
299 6 p.
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27 Critical contribution of the intracellular C-terminal region to TRESK channel activity is revealed by the epithelial Na+ current ratio method Debreczeni, Dorina

299 6 p.
artikel
28 Crosstalk of protein clearance, inflammasome, and Ca2+ channels in retinal pigment epithelium derived from age-related macular degeneration patients Karema-Jokinen, Viivi

299 6 p.
artikel
29 CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels Tanzo, Julia T.

299 6 p.
artikel
30 Degradation of EGFR on lung epithelial cells by neutrophil elastase contributes to the aggravation of pneumococcal pneumonia Isono, Toshihito

299 6 p.
artikel
31 Deletions of MGF110-9L and MGF360-9L from African swine fever virus are highly attenuated in swine and confer protection against homologous challenge Li, Dan

299 6 p.
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32 Development of the nonreceptor tyrosine kinase FER-targeting PROTACs as a potential strategy for antagonizing ovarian cancer cell motility and invasiveness Zhang, Yanchun

299 6 p.
artikel
33 Diarylheptanoid 35d overcomes EGFR TKI resistance by inducing hsp70-mediated lysosomal degradation of EGFR in EGFR-mutant lung adenocarcinoma Hong, Xuan

299 6 p.
artikel
34 Domain-specific modulatory effects of phosphomimetic substitutions on liquid-liquid phase separation of tau protein Boyko, Solomiia

299 6 p.
artikel
35 Dynamic protein deacetylation is a limited carbon source for acetyl-CoA–dependent metabolism Soaita, Ioana

299 6 p.
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36 Expanding the family of genetically encoded voltage indicators with a candidate Heliorhodopsin exhibiting near-infrared fluorescence Ganapathy, Srividya

299 6 p.
artikel
37 Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner Wu, Yifei

299 6 p.
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38 Fatty acid elongases 1-3 have distinct roles in mitochondrial function, growth, and lipid homeostasis in Trypanosoma cruzi Pagura, Lucas

299 6 p.
artikel
39 FcγRIIA-specific DARPins as novel tools in blood cell analysis and platelet aggregation Riechert, Vanessa

299 6 p.
artikel
40 Ferric uptake regulator (Fur) binds a [2Fe-2S] cluster to regulate intracellular iron homeostasis in Escherichia coli Fontenot, Chelsey R.

299 6 p.
artikel
41 GH20 and GH84 β-N-acetylglucosaminidases with different linkage specificities underpin mucin O-glycan breakdown capability of Bifidobacterium bifidum Takada, Hiromi

299 6 p.
artikel
42 GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS Koehn, Olivia J.

299 6 p.
artikel
43 Hes1 marks peri-condensation mesenchymal cells that generate both chondrocytes and perichondrial cells in early bone development Matsushita, Yuki

299 6 p.
artikel
44 HRD1 promotes non-small cell lung carcinoma metastasis by blocking autophagy-mediated MIEN1 degradation Zeng, Cheng

299 6 p.
artikel
45 HSP90α is needed for the survival of rod photoreceptors and regulates the expression of rod PDE6 subunits Munezero, Daniella

299 6 p.
artikel
46 Human seven-β-strand (METTL) methyltransferases - conquering the universe of protein lysine methylation Falnes, Pål Ø.

299 6 p.
artikel
47 Human TMEM2 is not a catalytic hyaluronidase, but a regulator of hyaluronan metabolism via HYBID (KIAA1199/CEMIP) and HAS2 expression Sato, Shinya

299 6 p.
artikel
48 Identification and classification of papain-like cysteine proteinases Ozhelvaci, Fatih

299 6 p.
artikel
49 Identification of a druggable pocket of the calcium-activated chloride channel TMEM16A in its open state Shi, Sai

299 6 p.
artikel
50 Identification of a novel amphioxus leucine-rich repeat receptor involved in phagocytosis reveals a role for Slit2-N-type LRR in bacterial elimination Zhan, Yanli

299 6 p.
artikel
51 Identification of novel coenzyme Q10 biosynthetic proteins Coq11 and Coq12 in Schizosaccharomyces pombe Nishida, Ikuhisa

299 6 p.
artikel
52 Identification of SARS-CoV-2 PLpro and 3CLpro human proteome substrates using substrate phage display coupled with protein network analysis Zhao, Kai

299 6 p.
artikel
53 IgG Fc-binding protein positively regulates the assembly of pore-forming protein complex βγ-CAT evolved to drive cell vesicular delivery and transport Bian, Xianling

299 6 p.
artikel
54 IL4i1 and IDO1: Oxidases that control a tryptophan metabolic nexus in cancer Zeitler, Leonie

299 6 p.
artikel
55 Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant Wallace, Michael J.

299 6 p.
artikel
56 Indoleamine dioxygenase and tryptophan dioxygenase activities are regulated through control of cell heme allocation by nitric oxide Biswas, Pranjal

299 6 p.
artikel
57 Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development Boulton, Stephen

299 6 p.
artikel
58 In silico interrogation of the miRNAome of infected hematopoietic cells to predict processes important for human cytomegalovirus latent infection Murray, M.J.

299 6 p.
artikel
59 Interaction between poly(A)–binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response Oliveira, A.G.

299 6 p.
artikel
60 Interaction with single-stranded DNA-binding protein modulates Escherichia coli RadD DNA repair activities Osorio Garcia, Miguel A.

299 6 p.
artikel
61 Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy–linked E40K mutation Hashimoto, Kei

299 6 p.
artikel
62 Investigating the mechanism of photoisomerization in jellyfish rhodopsin with the counterion at an atypical position Inukai, Shino

299 6 p.
artikel
63 Kinetic analysis of RNA cleavage by coronavirus Nsp15 endonuclease: Evidence for acid–base catalysis and substrate-dependent metal ion activation Huang, Tong

299 6 p.
artikel
64 Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners Xu, Yidan

299 6 p.
artikel
65 Mapping N- to C-terminal allosteric coupling through disruption of a putative CD74 activation site in D-dopachrome tautomerase Chen, Emily

299 6 p.
artikel
66 miR-147a targets ZEB2 to regulate ox-LDL-induced monocyte adherence to HUVECs, atherosclerotic plaque formation, and stability in atherosclerosis Chen, Fengying

299 6 p.
artikel
67 Mitochondrial membrane potential instability on reperfusion after ischemia does not depend on mitochondrial Ca2+ uptake Ashok, Deepthi

299 6 p.
artikel
68 Molecular determinants for Rous sarcoma virus intasome assemblies involved in retroviral integration Bera, Sibes

299 6 p.
artikel
69 Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity Hollander, Michael J.

299 6 p.
artikel
70 Nanobody inhibitors of Plexin-B1 identify allostery in plexin–semaphorin interactions and signaling Cowan, Richard

299 6 p.
artikel
71 Ndel1 disfavors dynein–dynactin–adaptor complex formation in two distinct ways Garrott, Sharon R.

299 6 p.
artikel
72 Neutrophil elastase decreases SARS-CoV-2 spike protein binding to human bronchial epithelia by clipping ACE-2 ectodomain from the epithelial surface Kummarapurugu, Apparao B.

299 6 p.
artikel
73 Noncovalent interactions that tune the reactivities of the flavins in bifurcating electron transferring flavoprotein González-Viegas, María

299 6 p.
artikel
74 Novel machine learning method allerStat identifies statistically significant allergen-specific patterns in protein sequences Goto, Kento

299 6 p.
artikel
75 Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P2 hydrolysis in the plasma membrane Chen, Huanzhao

299 6 p.
artikel
76 O-GlcNAcylation promotes the cytosolic localization of the m6A reader YTHDF1 and colorectal cancer tumorigenesis Li, Jie

299 6 p.
artikel
77 Opening of capsaicin receptor TRPV1 is stabilized equally by its four subunits Li, Shisheng

299 6 p.
artikel
78 Orthogonal approaches required to measure proteasome composition and activity in mammalian brain tissue Türker, Fulya

299 6 p.
artikel
79 Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis Bozonet, Stephanie M.

299 6 p.
artikel
80 Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression Yeon, Minjeong

299 6 p.
artikel
81 Peptidoglycan recognition in Drosophila is mediated by LysMD3/4 Snee, Mark

299 6 p.
artikel
82 Pharmacological inhibition of DNMT1 restores macrophage autophagy and M2 polarization in Western diet–induced nonalcoholic fatty liver disease Pant, Rajat

299 6 p.
artikel
83 PKA mediates modality-specific modulation of the mechanically gated ion channel PIEZO2 Schaefer, Irina

299 6 p.
artikel
84 Plasmodium parasitophorous vacuole membrane protein Pfs16 promotes malaria transmission by silencing mosquito immunity Ramelow, Julian

299 6 p.
artikel
85 Polypyrimidine tract binding protein 1 (PTBP1) contains a novel regulatory sequence, the rBH3, that binds the prosurvival protein MCL1 Carico, Christine

299 6 p.
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86 Pregranulosa cell–derived FGF23 protects oocytes from premature apoptosis during primordial follicle formation by inhibiting p38 MAPK in mice Zhu, Zijian

299 6 p.
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87 Protein–protein interactions in the Mla lipid transport system probed by computational structure prediction and deep mutational scanning MacRae, Mark R.

299 6 p.
artikel
88 RAD51–WSS1-dependent genetic pathways are essential for DNA–protein crosslink repair and pathogenesis in Candida albicans Kumari, Premlata

299 6 p.
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89 Ral GTPase promotes metastasis of pancreatic ductal adenocarcinoma via elevation of TGF-β1 production Cao, Mingxin

299 6 p.
artikel
90 Reactive sulfur species disaggregate the SQSTM1/p62-based aggresome-like induced structures via the HSP70 induction and prevent parthanatos Yamada, Yutaro

299 6 p.
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91 Reduced APPL1 impairs osteogenic differentiation of mesenchymal stem cells by facilitating MGP expression to disrupt the BMP2 pathway in osteoporosis Yuan, Weiquan

299 6 p.
artikel
92 Regulatory ligand binding in plant chalcone isomerase–like (CHIL) proteins Wolf-Saxon, Emma R.

299 6 p.
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93 Role of condensates in modulating DNA repair pathways and its implication for chemoresistance Dall’Agnese, Giuseppe

299 6 p.
artikel
94 Screening the Thermotoga maritima genome for new wide-spectrum nucleoside and nucleotide kinases Winkler, Katja F.

299 6 p.
artikel
95 Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis Butovich, Igor A.

299 6 p.
artikel
96 Selective inhibitors of the PSEN1–gamma-secretase complex Serneels, Lutgarde

299 6 p.
artikel
97 Single-molecule visualization of Pif1 helicase translocation on single-stranded DNA Mustafi, Mainak

299 6 p.
artikel
98 Solubilization, purification, and characterization of the hexameric form of phosphatidylserine synthase from Candida albicans Zhou, Yue

299 6 p.
artikel
99 Spatiotemporal regulation of the BarA/UvrY two-component signaling system Contreras, Fernanda Urias

299 6 p.
artikel
100 Sphingosine-1-phosphate and its receptors in vascular endothelial and lymphatic barrier function Weigel, Cynthia

299 6 p.
artikel
101 Stimulating β-adrenergic receptors promotes synaptic potentiation by switching CaMKII movement from LTD to LTP mode Larsen, Matthew E.

299 6 p.
artikel
102 Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis Wan, Tao

299 6 p.
artikel
103 Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation Jin, Gaowei

299 6 p.
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104 Structural changes in NOTCH3 induced by CADASIL mutations: Role of cysteine and non-cysteine alterations Lee, Soo Jung

299 6 p.
artikel
105 Structural dynamics reveal subtype-specific activation and inhibition of influenza virus hemagglutinin Garcia, Natalie K.

299 6 p.
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106 Structural insights into DNA recognition by the BEN domain of the transcription factor BANP Liu, Ke

299 6 p.
artikel
107 Structure of the complex between calmodulin and a functional construct of eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor Piserchio, Andrea

299 6 p.
artikel
108 Structures of Get3d reveal a distinct architecture associated with the emergence of photosynthesis Barlow, Alexandra N.

299 6 p.
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109 TFCP2 is a transcriptional regulator of heparan sulfate assembly and melanoma cell growth Basu, Amrita

299 6 p.
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110 The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C-Cdh1 E3 ubiquitin ligase activity Awadia, Sahezeel

299 6 p.
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111 The cannabinoid dehydroxylcannabidiol suppresses neuropathic pain by upregulating a spinal glycine receptor-mediated compensation mechanism Xia, Jing

299 6 p.
artikel
112 The host antiviral protein SAMHD1 suppresses NF-κB activation by interacting with the IKK complex during inflammatory responses and viral infection Yang, Hua

299 6 p.
artikel
113 The novel chloroplast glucose transporter pGlcT2 affects adaptation to extended light periods Valifard, Marzieh

299 6 p.
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114 The NSs protein of severe fever with thrombocytopenia syndrome virus differentially inhibits the type 1 interferon response among animal species Yoshikawa, Rokusuke

299 6 p.
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115 The ribosomal S6 kinase 2 (RSK2)–SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling Lopez, Jocelyne

299 6 p.
artikel
116 The role of high cholesterol in SARS-CoV-2 infectivity Wang, Hao

299 6 p.
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117 The Sec1–Munc18 protein VPS33B forms a uniquely bidirectional complex with VPS16B Liu, Richard J.Y.

299 6 p.
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118 The sphingolipids ceramide and inositol phosphorylceramide protect the Leishmania major membrane from sterol-specific toxins Haram, Chaitanya S.

299 6 p.
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119 The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation Khella, Mina S.

299 6 p.
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120 The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes Ma, Haixia

299 6 p.
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121 Transcription regulation by CarD in mycobacteria is guided by basal promoter kinetics Zhu, Dennis X.

299 6 p.
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122 Two C18 hydroxy-cyclohexenone fatty acids from mammalian epidermis: Potential relation to 12R-lipoxygenase and covalent binding of ceramides Brash, Alan R.

299 6 p.
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123 Utilization of dietary mixed-linkage β-glucans by the Firmicute Blautia producta Singh, Ravindra Pal

299 6 p.
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124 VBP1 negatively regulates CHIP and selectively inhibits the activity of hypoxia-inducible factor (HIF)-1α but not HIF-2α Yue, Yiming

299 6 p.
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                             124 gevonden resultaten
 
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