nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A bivalent β-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A
|
Wang, Chongyang |
|
|
299 |
4 |
p. |
artikel |
2 |
Activation of Gcn2 by small molecules designed to be inhibitors
|
Carlson, Kenneth R. |
|
|
299 |
4 |
p. |
artikel |
3 |
An engineered N-acyltransferase-LOV2 domain fusion protein enables light-inducible allosteric control of enzymatic activity
|
Reynolds, J.A. |
|
|
299 |
4 |
p. |
artikel |
4 |
An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11
|
Huang, Ji |
|
|
299 |
4 |
p. |
artikel |
5 |
An optimized reporter of the transcription factor hypoxia-inducible factor 1α reveals complex HIF-1α activation dynamics in single cells
|
Jeknić, Stevan |
|
|
299 |
4 |
p. |
artikel |
6 |
A novel calcium channel Cavβ2 splice variant with unique properties predominates in the retina
|
Seitter, Hartwig |
|
|
299 |
4 |
p. |
artikel |
7 |
A protein bridge to death between the ER and mitochondria
|
Lin, Jialing |
|
|
299 |
4 |
p. |
artikel |
8 |
A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus
|
Whaley, Sarah G. |
|
|
299 |
4 |
p. |
artikel |
9 |
A subfamily classification to choreograph the diverse activities within glycoside hydrolase family 31
|
Arumapperuma, Thimali |
|
|
299 |
4 |
p. |
artikel |
10 |
ATP and its metabolite adenosine cooperatively upregulate the antigen-presenting molecules on dendritic cells leading to IFN-γ production by T cells
|
Furuta, Kazuyuki |
|
|
299 |
4 |
p. |
artikel |
11 |
Atypical histone targets of PHD fingers
|
Black, Joshua C. |
|
|
299 |
4 |
p. |
artikel |
12 |
Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine ceramides
|
Ota, Ai |
|
|
299 |
4 |
p. |
artikel |
13 |
Blockade of CD47 function attenuates restenosis by promoting smooth muscle cell efferocytosis and inhibiting their migration and proliferation
|
Govatati, Suresh |
|
|
299 |
4 |
p. |
artikel |
14 |
Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver
|
Fakih, Rayan |
|
|
299 |
4 |
p. |
artikel |
15 |
Carnosic acid inhibits secretion of allergic inflammatory mediators in IgE-activated mast cells via direct regulation of Syk activation
|
Crozier, Robert W.E. |
|
|
299 |
4 |
p. |
artikel |
16 |
Citrullinated human and murine MOG35–55 display distinct biophysical and biochemical behavior
|
Doelman, W. |
|
|
299 |
4 |
p. |
artikel |
17 |
Coevolutionary signals in metabotropic glutamate receptors capture residue contacts and long-range functional interactions
|
Huh, Eunna |
|
|
299 |
4 |
p. |
artikel |
18 |
Conserved folding landscape of monomeric initiator caspases
|
Nag, Mithun |
|
|
299 |
4 |
p. |
artikel |
19 |
Constitutive and induced forms of membrane-bound proteinase 3 interact with antineutrophil cytoplasmic antibodies and promote immune activation of neutrophils
|
Carla Guarino, |
|
|
299 |
4 |
p. |
artikel |
20 |
Correction: Biochemical and structural basis of sialic acid utilization by gut microbes
|
Bell, Andrew |
|
|
299 |
4 |
p. |
artikel |
21 |
Correction: Residues forming the gating regions of asymmetric multidrug transporter Pdr5 also play roles in conformational switching and protein folding
|
Alhumaidi, Maryam |
|
|
299 |
4 |
p. |
artikel |
22 |
Cover
|
|
|
|
299 |
4 |
p. |
artikel |
23 |
Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells
|
Li, Xinyue |
|
|
299 |
4 |
p. |
artikel |
24 |
Cryo-EM reveals the membrane-binding phenomenon of EspB, a virulence factor of the mycobacterial type VII secretion system
|
Sengupta, Nayanika |
|
|
299 |
4 |
p. |
artikel |
25 |
Cryo-EM structure of amyloid fibril formed by α-synuclein hereditary A53E mutation reveals a distinct protofilament interface
|
Sun, Chuanqi |
|
|
299 |
4 |
p. |
artikel |
26 |
Designer molecules of the synaptic organizer MDGA1 reveal 3D conformational control of biological function
|
Lee, Hubert |
|
|
299 |
4 |
p. |
artikel |
27 |
Design, synthesis, and mechanism of action of novel μ-conotoxin KIIIA analogues for inhibition of the voltage-gated sodium channel Nav1.7
|
Zhao, Zitong |
|
|
299 |
4 |
p. |
artikel |
28 |
Differential contributions of phosphotransferases CEPT1 and CHPT1 to phosphatidylcholine homeostasis and lipid droplet biogenesis
|
Dorighello, Gabriel |
|
|
299 |
4 |
p. |
artikel |
29 |
Differential regulation of phosphorylation, structure, and stability of circadian clock protein FRQ isoforms
|
Chen, Xianyun |
|
|
299 |
4 |
p. |
artikel |
30 |
Differential role for rapid proteostasis in Rho GTPase-mediated control of quiescent endothelial integrity
|
Podieh, Fabienne |
|
|
299 |
4 |
p. |
artikel |
31 |
Differentiation-linked changes in the biosynthesis and turnover of sphingomyelins in rat male germ cells: Genes involved and effects of testosterone
|
Santiago Valtierra, Florencia X. |
|
|
299 |
4 |
p. |
artikel |
32 |
Disruption of Ephx2 in cardiomyocytes but not endothelial cells improves functional recovery after ischemia-reperfusion in isolated mouse hearts
|
Edin, Matthew L. |
|
|
299 |
4 |
p. |
artikel |
33 |
Egg envelope formation of medaka Oryzias latipes requires ZP proteins originating from both the liver and ovary
|
Yokokawa, Reo |
|
|
299 |
4 |
p. |
artikel |
34 |
Elucidation of the ferrichrome siderophore biosynthetic pathway in albomycin-producing Streptomyces sp. ATCC 700974
|
Li, Zhilei |
|
|
299 |
4 |
p. |
artikel |
35 |
ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival
|
Das, Shreya |
|
|
299 |
4 |
p. |
artikel |
36 |
Escherichia coli has robust regulatory mechanisms against elevated peptidoglycan cleavage by lytic transglycosylases
|
Liang, Yaquan |
|
|
299 |
4 |
p. |
artikel |
37 |
Expression of GnT-III decreases chemoresistance via negatively regulating P-glycoprotein expression: Involvement of the TNFR2-NF-κB signaling pathway
|
Song, Wanli |
|
|
299 |
4 |
p. |
artikel |
38 |
EZH2 W113C is a gain-of-function mutation in B-cell lymphoma enabling both PRC2 methyltransferase activation and tazemetostat resistance
|
Chu, Liping |
|
|
299 |
4 |
p. |
artikel |
39 |
Glycolipid transfer protein knockout disrupts vesicle trafficking to the plasma membrane
|
Nurmi, Henrik |
|
|
299 |
4 |
p. |
artikel |
40 |
Gβγ subunits colocalize with RNA polymerase II and regulate transcription in cardiac fibroblasts
|
Khan, Shahriar M. |
|
|
299 |
4 |
p. |
artikel |
41 |
Heat shock factor 1 induces a short burst of transcription of the clock gene Per2 during interbout arousal in mammalian hibernation
|
Takamatsu, Nobuhiko |
|
|
299 |
4 |
p. |
artikel |
42 |
Heparin and calreticulin interact on the surface of early G0/G1 dividing rat mesangial cells to regulate hyperglycemic glucose-induced responses
|
Wang, Andrew Jun |
|
|
299 |
4 |
p. |
artikel |
43 |
Hydroxysteroid 17β-dehydrogenase 11 accumulation on lipid droplets promotes ethanol-induced cellular steatosis
|
Thomes, Paul G. |
|
|
299 |
4 |
p. |
artikel |
44 |
Interaction of the bacterial division regulator MinE with lipid bicelles studied by NMR spectroscopy
|
Cai, Mengli |
|
|
299 |
4 |
p. |
artikel |
45 |
Lipidomic profiling of rat hepatic stellate cells during activation reveals a two-stage process accompanied by increased levels of lysosomal lipids
|
Molenaar, Martijn R. |
|
|
299 |
4 |
p. |
artikel |
46 |
Membrane lipid remodeling modulates γ-secretase processivity
|
Dawkins, Edgar |
|
|
299 |
4 |
p. |
artikel |
47 |
Mismatch repair operates at the replication fork in direct competition with mismatch extension by DNA polymerase δ
|
Klassen, Roland |
|
|
299 |
4 |
p. |
artikel |
48 |
Molecular basis of Q-length selectivity for the MW1 antibody–huntingtin interaction
|
Bravo-Arredondo, Jose M. |
|
|
299 |
4 |
p. |
artikel |
49 |
Molecular determinants for differential activation of the bile acid receptor from the pathogen Vibrio parahaemolyticus
|
Zou, Angela J. |
|
|
299 |
4 |
p. |
artikel |
50 |
Molecular dynamics simulations reveal the importance of amyloid-beta oligomer β-sheet edge conformations in membrane permeabilization
|
Matthes, Dirk |
|
|
299 |
4 |
p. |
artikel |
51 |
Mutation of a distal gating residue modulates NADH binding in NADH:Quinone oxidoreductase from Pseudomonas aeruginosa PAO1
|
Moni, Bilkis Mehrin |
|
|
299 |
4 |
p. |
artikel |
52 |
N-glycan antennal modifications are altered in Caenorhabditis elegans lacking the HEX-4 N-acetylgalactosamine-specific hexosaminidase
|
Paschinger, Katharina |
|
|
299 |
4 |
p. |
artikel |
53 |
Nitration-mediated activation of the small GTPase RhoA stimulates cellular glycolysis through enhanced mitochondrial fission
|
Lu, Qing |
|
|
299 |
4 |
p. |
artikel |
54 |
NMR characterization of an assembling RHIM (RIP homotypic interaction motif) amyloid reveals a cryptic region for self-recognition
|
Pham, Chi L.L. |
|
|
299 |
4 |
p. |
artikel |
55 |
NMR structure of emfourin, a novel protein metalloprotease inhibitor: Insights into the mechanism of action
|
Bozin, Timur N. |
|
|
299 |
4 |
p. |
artikel |
56 |
Nucleotide metabolism is linked to cysteine availability
|
Allen, Annamarie E. |
|
|
299 |
4 |
p. |
artikel |
57 |
Opposing regulation of the Nα-trimethylase METTL11A by its family members METTL11B and METTL13
|
Parker, Haley V. |
|
|
299 |
4 |
p. |
artikel |
58 |
Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3
|
Hu, Tingfei |
|
|
299 |
4 |
p. |
artikel |
59 |
p38 MAPK and MKP-1 control the glycolytic program via the bifunctional glycolysis regulator PFKFB3 during sepsis
|
Mager, Carli E. |
|
|
299 |
4 |
p. |
artikel |
60 |
Posttranslational regulation of liver kinase B1 in human cancer
|
Hu, Lanlin |
|
|
299 |
4 |
p. |
artikel |
61 |
Probing dietary triacylglycerol metabolism and meibogenesis in mice: A stable isotope-labeled tracer liquid chromatography–tandem mass spectrometry study
|
Butovich, Igor A. |
|
|
299 |
4 |
p. |
artikel |
62 |
Pyridine-containing substrate analogs are restricted from accessing the human cytochrome P450 8B1 active site by tryptophan 281
|
Liu, Jinghan |
|
|
299 |
4 |
p. |
artikel |
63 |
Reciprocal regulatory balance within the CLEC16A–RNF41 mitophagy complex depends on an intrinsically disordered protein region
|
Gingerich, Morgan A. |
|
|
299 |
4 |
p. |
artikel |
64 |
Regulated rapid round trips: Endocytotic cycling of the dopamine transporter shapes motor learning
|
Freissmuth, Michael |
|
|
299 |
4 |
p. |
artikel |
65 |
Release of immunomodulatory peptides at bacterial membrane interfaces as a novel strategy to fight microorganisms
|
Viana de Freitas, Thiago |
|
|
299 |
4 |
p. |
artikel |
66 |
RKIP localizes to the nucleus through a bipartite nuclear localization signal and interaction with importin α to regulate mitotic progression
|
Argueta, Christian E. |
|
|
299 |
4 |
p. |
artikel |
67 |
s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons
|
Maruo, Tomohiko |
|
|
299 |
4 |
p. |
artikel |
68 |
Selective PPARγ modulator diosmin improves insulin sensitivity and promotes browning of white fat
|
Yu, Jian |
|
|
299 |
4 |
p. |
artikel |
69 |
Serine 970 of RNA helicase MOV10 is phosphorylated and controls unfolding activity and fate of mRNAs targeted for AGO2-mediated silencing
|
Nawaz, Aatiqa |
|
|
299 |
4 |
p. |
artikel |
70 |
SET7 methylates the deubiquitinase OTUB1 at Lys 122 to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis
|
Deng, Hongyan |
|
|
299 |
4 |
p. |
artikel |
71 |
Structural analysis of the P132L disease mutation in caveolin-1 reveals its role in the assembly of oligomeric complexes
|
Han, Bing |
|
|
299 |
4 |
p. |
artikel |
72 |
Structural basis for reduced ribosomal A-site fidelity in response to P-site codon–anticodon mismatches
|
Nguyen, Ha An |
|
|
299 |
4 |
p. |
artikel |
73 |
Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor diversity
|
Wu, Daichao |
|
|
299 |
4 |
p. |
artikel |
74 |
Structure and dynamics of ESCRT-III membrane remodeling proteins by high-speed atomic force microscopy
|
Jukic, Nebojsa |
|
|
299 |
4 |
p. |
artikel |
75 |
Structure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies
|
Bruun, Theodora U.J. |
|
|
299 |
4 |
p. |
artikel |
76 |
Structures of calmodulin–melittin complexes show multiple binding modes lacking classical anchoring interactions
|
Dürvanger, Zsolt |
|
|
299 |
4 |
p. |
artikel |
77 |
Suppression of multiple phenotypic and RNA processing defects by overexpression of oligoribonuclease in Escherichia coli
|
Jain, Chaitanya |
|
|
299 |
4 |
p. |
artikel |
78 |
Targeted protein posttranslational modifications by chemically induced proximity for cancer therapy
|
Peng, Yunhua |
|
|
299 |
4 |
p. |
artikel |
79 |
The abscisic acid–responsive element binding factors MAPKKK18 module regulates abscisic acid–induced leaf senescence in Arabidopsis
|
Zhao, Guoying |
|
|
299 |
4 |
p. |
artikel |
80 |
The aryl sulfonamide indisulam inhibits gastric cancer cell migration by promoting the ubiquitination and degradation of the transcription factor ZEB1
|
Lu, Jiaqi |
|
|
299 |
4 |
p. |
artikel |
81 |
The CIS association of CD47 with integrin Mac-1 regulates macrophage responses by stabilizing the extended integrin conformation
|
Podolnikova, Nataly P. |
|
|
299 |
4 |
p. |
artikel |
82 |
The C-terminal domains of ADAMTS1 contain exosites involved in its proteoglycanase activity
|
Minns, Alexander Frederick |
|
|
299 |
4 |
p. |
artikel |
83 |
The CTP-binding domain is disengaged from the DNA-binding domain in a cocrystal structure of Bacillus subtilis Noc–DNA complex
|
Sukhoverkov, Kirill V. |
|
|
299 |
4 |
p. |
artikel |
84 |
The 9-1-1 DNA clamp subunit RAD1 forms specific interactions with clamp loader RAD17, revealing functional implications for binding-protein RHINO
|
Hara, Kodai |
|
|
299 |
4 |
p. |
artikel |
85 |
The function of the phytoplasma effector SWP12 depends on the properties of two key amino acids
|
Bai, Bixin |
|
|
299 |
4 |
p. |
artikel |
86 |
The histamine H3 receptor modulates dopamine D2 receptor–dependent signaling pathways and mouse behaviors
|
Xu, Jian |
|
|
299 |
4 |
p. |
artikel |
87 |
The 5-lipoxygenase/cyclooxygenase-2 cross-over metabolite, hemiketal E2, enhances VEGFR2 activation and promotes angiogenesis
|
Nakashima, Fumie |
|
|
299 |
4 |
p. |
artikel |
88 |
The mode of action of tapasin on major histocompatibility class I (MHC-I) molecules
|
Lan, By Huan |
|
|
299 |
4 |
p. |
artikel |
89 |
The polar amino acid in the TatA transmembrane helix is not strictly necessary for protein function
|
Hao, Binhan |
|
|
299 |
4 |
p. |
artikel |
90 |
The ROK kinase N-acetylglucosamine kinase uses a sequential random enzyme mechanism with successive conformational changes upon each substrate binding
|
Roy, Sumita |
|
|
299 |
4 |
p. |
artikel |
91 |
The signaling protein GIV/Girdin mediates the Nephrin-dependent insulin secretion of pancreatic islet β cells in response to high glucose
|
Wang, Hao |
|
|
299 |
4 |
p. |
artikel |
92 |
The 5′UTR of HCoV-OC43 adopts a topologically constrained structure to intrinsically repress translation
|
Mackeown, Matthew |
|
|
299 |
4 |
p. |
artikel |
93 |
The YAP–TEAD4 complex promotes tumor lymphangiogenesis by transcriptionally upregulating CCBE1 in colorectal cancer
|
Song, Jinglue |
|
|
299 |
4 |
p. |
artikel |
94 |
Thymine DNA glycosylase is an RNA-binding protein with high selectivity for G-rich sequences
|
McGregor, Lauren A. |
|
|
299 |
4 |
p. |
artikel |
95 |
Toward an understanding of the conformational plasticity of S100A8 and S100A9 Ca2+-binding proteins
|
Polakowska, Magdalena |
|
|
299 |
4 |
p. |
artikel |
96 |
Two activating phosphorylation sites of Pbs2 MAP2K in the yeast HOG pathway are differentially dephosphorylated by four PP2C phosphatases Ptc1–Ptc4
|
Tatebayashi, Kazuo |
|
|
299 |
4 |
p. |
artikel |
97 |
UHMK1 is a novel splicing regulatory kinase
|
Arfelli, Vanessa C. |
|
|
299 |
4 |
p. |
artikel |
98 |
Understanding a protein fold: The physics, chemistry, and biology of α-helical coiled coils
|
Woolfson, Derek N. |
|
|
299 |
4 |
p. |
artikel |
99 |
Withdrawal: p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity
|
Normand, Guillaume |
|
|
299 |
4 |
p. |
artikel |