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                             99 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A bivalent β-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A Wang, Chongyang

299 4 p.
artikel
2 Activation of Gcn2 by small molecules designed to be inhibitors Carlson, Kenneth R.

299 4 p.
artikel
3 An engineered N-acyltransferase-LOV2 domain fusion protein enables light-inducible allosteric control of enzymatic activity Reynolds, J.A.

299 4 p.
artikel
4 An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11 Huang, Ji

299 4 p.
artikel
5 An optimized reporter of the transcription factor hypoxia-inducible factor 1α reveals complex HIF-1α activation dynamics in single cells Jeknić, Stevan

299 4 p.
artikel
6 A novel calcium channel Cavβ2 splice variant with unique properties predominates in the retina Seitter, Hartwig

299 4 p.
artikel
7 A protein bridge to death between the ER and mitochondria Lin, Jialing

299 4 p.
artikel
8 A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus Whaley, Sarah G.

299 4 p.
artikel
9 A subfamily classification to choreograph the diverse activities within glycoside hydrolase family 31 Arumapperuma, Thimali

299 4 p.
artikel
10 ATP and its metabolite adenosine cooperatively upregulate the antigen-presenting molecules on dendritic cells leading to IFN-γ production by T cells Furuta, Kazuyuki

299 4 p.
artikel
11 Atypical histone targets of PHD fingers Black, Joshua C.

299 4 p.
artikel
12 Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine ceramides Ota, Ai

299 4 p.
artikel
13 Blockade of CD47 function attenuates restenosis by promoting smooth muscle cell efferocytosis and inhibiting their migration and proliferation Govatati, Suresh

299 4 p.
artikel
14 Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver Fakih, Rayan

299 4 p.
artikel
15 Carnosic acid inhibits secretion of allergic inflammatory mediators in IgE-activated mast cells via direct regulation of Syk activation Crozier, Robert W.E.

299 4 p.
artikel
16 Citrullinated human and murine MOG35–55 display distinct biophysical and biochemical behavior Doelman, W.

299 4 p.
artikel
17 Coevolutionary signals in metabotropic glutamate receptors capture residue contacts and long-range functional interactions Huh, Eunna

299 4 p.
artikel
18 Conserved folding landscape of monomeric initiator caspases Nag, Mithun

299 4 p.
artikel
19 Constitutive and induced forms of membrane-bound proteinase 3 interact with antineutrophil cytoplasmic antibodies and promote immune activation of neutrophils Carla Guarino,

299 4 p.
artikel
20 Correction: Biochemical and structural basis of sialic acid utilization by gut microbes Bell, Andrew

299 4 p.
artikel
21 Correction: Residues forming the gating regions of asymmetric multidrug transporter Pdr5 also play roles in conformational switching and protein folding Alhumaidi, Maryam

299 4 p.
artikel
22 Cover
299 4 p.
artikel
23 Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells Li, Xinyue

299 4 p.
artikel
24 Cryo-EM reveals the membrane-binding phenomenon of EspB, a virulence factor of the mycobacterial type VII secretion system Sengupta, Nayanika

299 4 p.
artikel
25 Cryo-EM structure of amyloid fibril formed by α-synuclein hereditary A53E mutation reveals a distinct protofilament interface Sun, Chuanqi

299 4 p.
artikel
26 Designer molecules of the synaptic organizer MDGA1 reveal 3D conformational control of biological function Lee, Hubert

299 4 p.
artikel
27 Design, synthesis, and mechanism of action of novel μ-conotoxin KIIIA analogues for inhibition of the voltage-gated sodium channel Nav1.7 Zhao, Zitong

299 4 p.
artikel
28 Differential contributions of phosphotransferases CEPT1 and CHPT1 to phosphatidylcholine homeostasis and lipid droplet biogenesis Dorighello, Gabriel

299 4 p.
artikel
29 Differential regulation of phosphorylation, structure, and stability of circadian clock protein FRQ isoforms Chen, Xianyun

299 4 p.
artikel
30 Differential role for rapid proteostasis in Rho GTPase-mediated control of quiescent endothelial integrity Podieh, Fabienne

299 4 p.
artikel
31 Differentiation-linked changes in the biosynthesis and turnover of sphingomyelins in rat male germ cells: Genes involved and effects of testosterone Santiago Valtierra, Florencia X.

299 4 p.
artikel
32 Disruption of Ephx2 in cardiomyocytes but not endothelial cells improves functional recovery after ischemia-reperfusion in isolated mouse hearts Edin, Matthew L.

299 4 p.
artikel
33 Egg envelope formation of medaka Oryzias latipes requires ZP proteins originating from both the liver and ovary Yokokawa, Reo

299 4 p.
artikel
34 Elucidation of the ferrichrome siderophore biosynthetic pathway in albomycin-producing Streptomyces sp. ATCC 700974 Li, Zhilei

299 4 p.
artikel
35 ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival Das, Shreya

299 4 p.
artikel
36 Escherichia coli has robust regulatory mechanisms against elevated peptidoglycan cleavage by lytic transglycosylases Liang, Yaquan

299 4 p.
artikel
37 Expression of GnT-III decreases chemoresistance via negatively regulating P-glycoprotein expression: Involvement of the TNFR2-NF-κB signaling pathway Song, Wanli

299 4 p.
artikel
38 EZH2 W113C is a gain-of-function mutation in B-cell lymphoma enabling both PRC2 methyltransferase activation and tazemetostat resistance Chu, Liping

299 4 p.
artikel
39 Glycolipid transfer protein knockout disrupts vesicle trafficking to the plasma membrane Nurmi, Henrik

299 4 p.
artikel
40 Gβγ subunits colocalize with RNA polymerase II and regulate transcription in cardiac fibroblasts Khan, Shahriar M.

299 4 p.
artikel
41 Heat shock factor 1 induces a short burst of transcription of the clock gene Per2 during interbout arousal in mammalian hibernation Takamatsu, Nobuhiko

299 4 p.
artikel
42 Heparin and calreticulin interact on the surface of early G0/G1 dividing rat mesangial cells to regulate hyperglycemic glucose-induced responses Wang, Andrew Jun

299 4 p.
artikel
43 Hydroxysteroid 17β-dehydrogenase 11 accumulation on lipid droplets promotes ethanol-induced cellular steatosis Thomes, Paul G.

299 4 p.
artikel
44 Interaction of the bacterial division regulator MinE with lipid bicelles studied by NMR spectroscopy Cai, Mengli

299 4 p.
artikel
45 Lipidomic profiling of rat hepatic stellate cells during activation reveals a two-stage process accompanied by increased levels of lysosomal lipids Molenaar, Martijn R.

299 4 p.
artikel
46 Membrane lipid remodeling modulates γ-secretase processivity Dawkins, Edgar

299 4 p.
artikel
47 Mismatch repair operates at the replication fork in direct competition with mismatch extension by DNA polymerase δ Klassen, Roland

299 4 p.
artikel
48 Molecular basis of Q-length selectivity for the MW1 antibody–huntingtin interaction Bravo-Arredondo, Jose M.

299 4 p.
artikel
49 Molecular determinants for differential activation of the bile acid receptor from the pathogen Vibrio parahaemolyticus Zou, Angela J.

299 4 p.
artikel
50 Molecular dynamics simulations reveal the importance of amyloid-beta oligomer β-sheet edge conformations in membrane permeabilization Matthes, Dirk

299 4 p.
artikel
51 Mutation of a distal gating residue modulates NADH binding in NADH:Quinone oxidoreductase from Pseudomonas aeruginosa PAO1 Moni, Bilkis Mehrin

299 4 p.
artikel
52 N-glycan antennal modifications are altered in Caenorhabditis elegans lacking the HEX-4 N-acetylgalactosamine-specific hexosaminidase Paschinger, Katharina

299 4 p.
artikel
53 Nitration-mediated activation of the small GTPase RhoA stimulates cellular glycolysis through enhanced mitochondrial fission Lu, Qing

299 4 p.
artikel
54 NMR characterization of an assembling RHIM (RIP homotypic interaction motif) amyloid reveals a cryptic region for self-recognition Pham, Chi L.L.

299 4 p.
artikel
55 NMR structure of emfourin, a novel protein metalloprotease inhibitor: Insights into the mechanism of action Bozin, Timur N.

299 4 p.
artikel
56 Nucleotide metabolism is linked to cysteine availability Allen, Annamarie E.

299 4 p.
artikel
57 Opposing regulation of the Nα-trimethylase METTL11A by its family members METTL11B and METTL13 Parker, Haley V.

299 4 p.
artikel
58 Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3 Hu, Tingfei

299 4 p.
artikel
59 p38 MAPK and MKP-1 control the glycolytic program via the bifunctional glycolysis regulator PFKFB3 during sepsis Mager, Carli E.

299 4 p.
artikel
60 Posttranslational regulation of liver kinase B1 in human cancer Hu, Lanlin

299 4 p.
artikel
61 Probing dietary triacylglycerol metabolism and meibogenesis in mice: A stable isotope-labeled tracer liquid chromatography–tandem mass spectrometry study Butovich, Igor A.

299 4 p.
artikel
62 Pyridine-containing substrate analogs are restricted from accessing the human cytochrome P450 8B1 active site by tryptophan 281 Liu, Jinghan

299 4 p.
artikel
63 Reciprocal regulatory balance within the CLEC16A–RNF41 mitophagy complex depends on an intrinsically disordered protein region Gingerich, Morgan A.

299 4 p.
artikel
64 Regulated rapid round trips: Endocytotic cycling of the dopamine transporter shapes motor learning Freissmuth, Michael

299 4 p.
artikel
65 Release of immunomodulatory peptides at bacterial membrane interfaces as a novel strategy to fight microorganisms Viana de Freitas, Thiago

299 4 p.
artikel
66 RKIP localizes to the nucleus through a bipartite nuclear localization signal and interaction with importin α to regulate mitotic progression Argueta, Christian E.

299 4 p.
artikel
67 s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons Maruo, Tomohiko

299 4 p.
artikel
68 Selective PPARγ modulator diosmin improves insulin sensitivity and promotes browning of white fat Yu, Jian

299 4 p.
artikel
69 Serine 970 of RNA helicase MOV10 is phosphorylated and controls unfolding activity and fate of mRNAs targeted for AGO2-mediated silencing Nawaz, Aatiqa

299 4 p.
artikel
70 SET7 methylates the deubiquitinase OTUB1 at Lys 122 to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis Deng, Hongyan

299 4 p.
artikel
71 Structural analysis of the P132L disease mutation in caveolin-1 reveals its role in the assembly of oligomeric complexes Han, Bing

299 4 p.
artikel
72 Structural basis for reduced ribosomal A-site fidelity in response to P-site codon–anticodon mismatches Nguyen, Ha An

299 4 p.
artikel
73 Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor diversity Wu, Daichao

299 4 p.
artikel
74 Structure and dynamics of ESCRT-III membrane remodeling proteins by high-speed atomic force microscopy Jukic, Nebojsa

299 4 p.
artikel
75 Structure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies Bruun, Theodora U.J.

299 4 p.
artikel
76 Structures of calmodulin–melittin complexes show multiple binding modes lacking classical anchoring interactions Dürvanger, Zsolt

299 4 p.
artikel
77 Suppression of multiple phenotypic and RNA processing defects by overexpression of oligoribonuclease in Escherichia coli Jain, Chaitanya

299 4 p.
artikel
78 Targeted protein posttranslational modifications by chemically induced proximity for cancer therapy Peng, Yunhua

299 4 p.
artikel
79 The abscisic acid–responsive element binding factors MAPKKK18 module regulates abscisic acid–induced leaf senescence in Arabidopsis Zhao, Guoying

299 4 p.
artikel
80 The aryl sulfonamide indisulam inhibits gastric cancer cell migration by promoting the ubiquitination and degradation of the transcription factor ZEB1 Lu, Jiaqi

299 4 p.
artikel
81 The CIS association of CD47 with integrin Mac-1 regulates macrophage responses by stabilizing the extended integrin conformation Podolnikova, Nataly P.

299 4 p.
artikel
82 The C-terminal domains of ADAMTS1 contain exosites involved in its proteoglycanase activity Minns, Alexander Frederick

299 4 p.
artikel
83 The CTP-binding domain is disengaged from the DNA-binding domain in a cocrystal structure of Bacillus subtilis Noc–DNA complex Sukhoverkov, Kirill V.

299 4 p.
artikel
84 The 9-1-1 DNA clamp subunit RAD1 forms specific interactions with clamp loader RAD17, revealing functional implications for binding-protein RHINO Hara, Kodai

299 4 p.
artikel
85 The function of the phytoplasma effector SWP12 depends on the properties of two key amino acids Bai, Bixin

299 4 p.
artikel
86 The histamine H3 receptor modulates dopamine D2 receptor–dependent signaling pathways and mouse behaviors Xu, Jian

299 4 p.
artikel
87 The 5-lipoxygenase/cyclooxygenase-2 cross-over metabolite, hemiketal E2, enhances VEGFR2 activation and promotes angiogenesis Nakashima, Fumie

299 4 p.
artikel
88 The mode of action of tapasin on major histocompatibility class I (MHC-I) molecules Lan, By Huan

299 4 p.
artikel
89 The polar amino acid in the TatA transmembrane helix is not strictly necessary for protein function Hao, Binhan

299 4 p.
artikel
90 The ROK kinase N-acetylglucosamine kinase uses a sequential random enzyme mechanism with successive conformational changes upon each substrate binding Roy, Sumita

299 4 p.
artikel
91 The signaling protein GIV/Girdin mediates the Nephrin-dependent insulin secretion of pancreatic islet β cells in response to high glucose Wang, Hao

299 4 p.
artikel
92 The 5′UTR of HCoV-OC43 adopts a topologically constrained structure to intrinsically repress translation Mackeown, Matthew

299 4 p.
artikel
93 The YAP–TEAD4 complex promotes tumor lymphangiogenesis by transcriptionally upregulating CCBE1 in colorectal cancer Song, Jinglue

299 4 p.
artikel
94 Thymine DNA glycosylase is an RNA-binding protein with high selectivity for G-rich sequences McGregor, Lauren A.

299 4 p.
artikel
95 Toward an understanding of the conformational plasticity of S100A8 and S100A9 Ca2+-binding proteins Polakowska, Magdalena

299 4 p.
artikel
96 Two activating phosphorylation sites of Pbs2 MAP2K in the yeast HOG pathway are differentially dephosphorylated by four PP2C phosphatases Ptc1–Ptc4 Tatebayashi, Kazuo

299 4 p.
artikel
97 UHMK1 is a novel splicing regulatory kinase Arfelli, Vanessa C.

299 4 p.
artikel
98 Understanding a protein fold: The physics, chemistry, and biology of α-helical coiled coils Woolfson, Derek N.

299 4 p.
artikel
99 Withdrawal: p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity Normand, Guillaume

299 4 p.
artikel
                             99 gevonden resultaten
 
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