Digitale Bibliotheek
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                             112 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A “biphasic glycosyltransferase high-throughput screen” identifies novel anthraquinone glycosides in the diversification of phenolic natural products Mohideen, F. Ifthiha

299 3 p.
artikel
2 Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia Zhang, Hao

299 3 p.
artikel
3 Activation of protein arginine methyltransferase 1 and subsequent extension of moth lifespan is effected by the ROS/JNK/CREB signaling axis Zhang, Xiao-Shuai

299 3 p.
artikel
4 Aim18p and Aim46p are chalcone isomerase domain–containing mitochondrial hemoproteins in Saccharomyces cerevisiae Schmitz, Jonathan M.

299 3 p.
artikel
5 Analysis of mammalian circadian clock protein complexes over a circadian cycle Cao, Xuemei

299 3 p.
artikel
6 An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily Buša, Michal

299 3 p.
artikel
7 A new electrochemical method that mimics phosphorylation of the core tau peptide K18 enables kinetic and structural analysis of intermediates and assembly Masquelier, Eloise

299 3 p.
artikel
8 A novel compound targets the feline infectious peritonitis virus nucleocapsid protein and inhibits viral replication in cell culture Mohseni, Nazleen

299 3 p.
artikel
9 Apo-metallothionein-3 cooperatively forms tightly compact structures under physiological conditions Yuan, Amelia T.

299 3 p.
artikel
10 A structure-function analysis of chlorophyllase reveals a mechanism for activity regulation dependent on disulfide bonds Jo, Minshik

299 3 p.
artikel
11 A synthetic organelle approach to probe SNARE-mediated membrane fusion in a bacterial host Ferreras, Soledad

299 3 p.
artikel
12 Biochemical analysis of SARS-CoV-2 Nsp13 helicase implicated in COVID-19 and factors that regulate its catalytic functions Sommers, Joshua A.

299 3 p.
artikel
13 Biochemical and structural basis of sialic acid utilization by gut microbes Bell, Andrew

299 3 p.
artikel
14 Cardiolipin metabolism regulates expression of muscle transcription factor MyoD1 and muscle development Vo, Linh

299 3 p.
artikel
15 β-cell–selective inhibition of DNA damage response signaling by nitric oxide is associated with an attenuation in glucose uptake Yeo, Chay Teng

299 3 p.
artikel
16 Characterization of two distinct neutrophil serine protease–binding modes within a Staphylococcus aureus innate immune evasion protein family Gido, Carson D.

299 3 p.
artikel
17 chi sequences switch the RecBCD helicase–nuclease complex from degradative to replicative modes during the completion of DNA replication Hamilton, Nicklas A.

299 3 p.
artikel
18 Complex interaction network revealed by mutation of human telomerase ‘insertion in fingers’ and essential N-terminal domains and the telomere protein TPP1 Lambert-Lanteigne, Patrick

299 3 p.
artikel
19 Comprehensive characterization of complex glycosphingolipids in human pancreatic cancer tissues Hořejší, Karel

299 3 p.
artikel
20 Conformational dynamics control assembly of an extremely long bacteriophage tail tube Agnello, Emily

299 3 p.
artikel
21 Consensus design and engineering of an efficient and high-yield peptide asparaginyl ligase for protein cyclization and ligation Hemu, Xinya

299 3 p.
artikel
22 Conservation, abundance, glycosylation profile, and localization of the TSP protein family in Cryptosporidium parvum John, Alan

299 3 p.
artikel
23 Correction: E3 ubiquitin ligase PARK2, an inhibitor of melanoma cell growth, is repressed by the oncogenic ERK1/2-ELK1 transcriptional axis Montagnani, Valentina

299 3 p.
artikel
24 Correction: Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation Chaya, Taro

299 3 p.
artikel
25 Cover
299 3 p.
artikel
26 Cyclin A–CDK1 suppresses the expression of the CDK1 activator CDC25A to safeguard timely mitotic entry Ng, Lau Yan

299 3 p.
artikel
27 Depletion of plasma thymidine results in growth retardation and mitochondrial myopathy in mice overexpressing human thymidine phosphorylase Harada, Naomoto

299 3 p.
artikel
28 Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritis Wu, Yichen

299 3 p.
artikel
29 Disordered proteins mitigate the temperature dependence of site-specific binding free energies Thole, Joseph F.

299 3 p.
artikel
30 DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development Zhao, Simin

299 3 p.
artikel
31 Dynamics of the Synechococcus elongatus cytoskeletal GTPase FtsZ yields mechanistic and evolutionary insight into cyanobacterial and chloroplast FtsZs Porter, Katie J.

299 3 p.
artikel
32 Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5 Guhathakurta, Piyali

299 3 p.
artikel
33 Ectopic RING activity at the ER membrane differentially impacts ERAD protein quality control pathways Mehrtash, Adrian B.

299 3 p.
artikel
34 E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide Lee, Su Hyoun

299 3 p.
artikel
35 Enolpyruvate transferase MurAAA149E, identified during adaptation of Enterococcus faecium to daptomycin, increases stability of MurAA–MurG interaction Zhou, Yue

299 3 p.
artikel
36 Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2 Cross, Frederick R.

299 3 p.
artikel
37 Exploration of aminoacyl-tRNA synthetases from eukaryotic parasites for drug development Gill, Jasmita

299 3 p.
artikel
38 Extracellular intersubunit interactions modulate epithelial Na+ channel gating Zhang, Lei

299 3 p.
artikel
39 Fibril treatment changes protein interactions of tau and α-synuclein in human neurons Griffin, Tagan A.

299 3 p.
artikel
40 Fine spectral tuning of a flavin-binding fluorescent protein for multicolor imaging Nikolaev, Andrey

299 3 p.
artikel
41 Fitm2 is required for ER homeostasis and normal function of murine liver Bond, Laura M.

299 3 p.
artikel
42 Functional characterization of Vip3Aa from Bacillus thuringiensis reveals the contributions of specific domains to its insecticidal activity Jiang, Kun

299 3 p.
artikel
43 Goldilocks calcium concentrations and the regulation of oxidative phosphorylation: Too much, too little, or just right Vilas-Boas, Eloisa A.

299 3 p.
artikel
44 Group II metabotropic glutamate receptor activation attenuates acid-sensing ion channel currents in rat primary sensory neurons Li, Qing

299 3 p.
artikel
45 Hepatocyte estrogen sulfotransferase inhibition protects female mice from concanavalin A–induced T cell–mediated hepatitis independent of estrogens Wang, Jingyuan

299 3 p.
artikel
46 Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX6 Dong, Zhangji

299 3 p.
artikel
47 Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site Petrunak, Elyse M.

299 3 p.
artikel
48 Human DNA polymerase η promotes RNA-templated error-free repair of DNA double-strand breaks Chakraborty, Anirban

299 3 p.
artikel
49 Human uridine 5′-monophosphate synthase stores metabolic potential in inactive biomolecular condensates Kim-Holzapfel, Deborah M.

299 3 p.
artikel
50 Increased angiotensin II coupled with decreased Adra1a expression enhances cardiac hypertrophy in pregnancy-associated hypertensive mice Kim, Jun-Dal

299 3 p.
artikel
51 Influence of glycoprotein MUC1 on trafficking of the Ca2+-selective ion channels, TRPV5 and TRPV6, and on in vivo calcium homeostasis Al-bataineh, Mohammad M.

299 3 p.
artikel
52 Inhibiting O-GlcNAcylation impacts p38 and Erk1/2 signaling and perturbs cardiomyocyte hypertrophy Papanicolaou, Kyriakos N.

299 3 p.
artikel
53 Innate immune cell-intrinsic ketogenesis is dispensable for organismal metabolism and age-related inflammation Goldberg, Emily L.

299 3 p.
artikel
54 Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in the enteric nervous system Ito, Masatoshi

299 3 p.
artikel
55 Ion channel chameleons: Switching ion selectivity by alternative splicing Hsu, Allen L.

299 3 p.
artikel
56 IP3Rs puff along: A SNAPpy dance with IP3 and Ca2+ Nakhe, Arya Y.

299 3 p.
artikel
57 Lanpepsy is a novel lanthanide-binding protein involved in the lanthanide response of the obligate methylotroph Methylobacillus flagellatus Hemmann, Jethro L.

299 3 p.
artikel
58 Liquid–liquid phase separation of amyloid-β oligomers modulates amyloid fibrils formation Gui, Xinrui

299 3 p.
artikel
59 Long-chain polyunsaturated lipids associated with responsiveness to anti-PD-1 therapy are colocalized with immune infiltrates in the tumor microenvironment King, Mary E.

299 3 p.
artikel
60 Loss of fatty acid binding protein 3 ameliorates lipopolysaccharide-induced inflammation and endothelial dysfunction Nguyen, Hien C.

299 3 p.
artikel
61 Mass spectrometry imaging–based assays for aminotransferase activity reveal a broad substrate spectrum for a previously uncharacterized enzyme de Raad, Markus

299 3 p.
artikel
62 MceG stabilizes the Mce1 and Mce4 transporters in Mycobacterium tuberculosis Fieweger, Rachael A.

299 3 p.
artikel
63 Mitochondrial respiration reduces exposure of the nucleus to oxygen Mori, Mateus Prates

299 3 p.
artikel
64 Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin Amatsu, Sho

299 3 p.
artikel
65 Multifaceted functions of RNA-binding protein vigilin in gene silencing, genome stability, and autism-related disorders Mushtaq, Arjamand

299 3 p.
artikel
66 Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation Campolo, Nicolás

299 3 p.
artikel
67 Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling Sloan, Douglas C.

299 3 p.
artikel
68 O-GlcNAc transferase modulates the cellular endocytosis machinery by controlling the formation of clathrin-coated pits Rahmani, Sadia

299 3 p.
artikel
69 Oral arsenic administration to humanized UDP- glucuronosyltransferase 1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR Yang, Xiaojing

299 3 p.
artikel
70 Oxidation modulates LINGO2-induced inactivation of large conductance, Ca2+-activated potassium channels Dudem, Srikanth

299 3 p.
artikel
71 Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase η and reduces DNA synthesis fidelity Chang, Caleb

299 3 p.
artikel
72 Protein tyrosine phosphatase 69D is a substrate of protein O-mannosyltransferases 1-2 that is required for the wiring of sensory axons in Drosophila Monagas-Valentin, Pedro

299 3 p.
artikel
73 Pseudophosphorylation of Arabidopsis jasmonate biosynthesis enzyme lipoxygenase 2 via mutation of Ser600 inhibits enzyme activity Kaur, Diljot

299 3 p.
artikel
74 Receptor-binding domain of SARS-CoV-2 is a functional αv-integrin agonist Norris, Emma G.

299 3 p.
artikel
75 Residues E53, L55, H59, and G70 of the cellular receptor protein Tva mediate cell binding and entry of the novel subgroup K avian leukosis virus Li, Xinyi

299 3 p.
artikel
76 RhoA rescues cardiac senescence by regulating Parkin-mediated mitophagy Soh, Joanne Ern Chi

299 3 p.
artikel
77 Risk modeling of single-cell transcriptomes reveals the heterogeneity of immune infiltration in hepatocellular carcinoma Wang, Lu

299 3 p.
artikel
78 Rubredoxin 1 promotes the proper folding of D1 and is not required for heme b 559 assembly in Chlamydomonas photosystem II Calderon, Robert H.

299 3 p.
artikel
79 SARS-CoV-2–encoded ORF8 protein possesses complement inhibitory properties Kumar, Jitendra

299 3 p.
artikel
80 Saturated fatty acid– and/or monounsaturated fatty acid–containing phosphatidic acids selectively interact with heat shock protein 27 Yachida, Naoto

299 3 p.
artikel
81 Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation Barbieri, Guido

299 3 p.
artikel
82 Serine/threonine-protein kinase STK24 induces tumorigenesis by regulating the STAT3/VEGFA signaling pathway Lai, Senyan

299 3 p.
artikel
83 Staphylococcal Periscope proteins Aap, SasG, and Pls project noncanonical legume-like lectin adhesin domains from the bacterial surface Clark, Laura C.

299 3 p.
artikel
84 Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease Noske, Gabriela Dias

299 3 p.
artikel
85 Structural insights into the recognition of telomeric variant repeat TTGGGG by broad-complex, tramtrack and bric-à-brac - zinc finger protein ZBTB10 Wang, Suman

299 3 p.
artikel
86 Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors Liu, Shenping

299 3 p.
artikel
87 Structure of VanS from vancomycin-resistant enterococci: A sensor kinase with weak ATP binding Grasty, Kimberly C.

299 3 p.
artikel
88 Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code Herrmann, Eric

299 3 p.
artikel
89 The clathrin adaptor complex-1 and Rab12 regulate post-golgi trafficking of WT epidermal growth factor receptor (EGFR) Wang, Jinhui

299 3 p.
artikel
90 The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease Baek, Judy

299 3 p.
artikel
91 The Dengue virus protease NS2B3 cleaves cyclic GMP-AMP synthase to suppress cGAS activation Bhattacharya, Madhurima

299 3 p.
artikel
92 The β-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning Gogar, Rajleen K.

299 3 p.
artikel
93 The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes Song, Liu

299 3 p.
artikel
94 The Mfd protein is the transcription-repair coupling factor (TRCF) in Mycobacterium smegmatis Adebali, Ogun

299 3 p.
artikel
95 The mTORC2/AKT/VCP axis is associated with quality control of the stalled translation of poly(GR) dipeptide repeats in C9-ALS/FTD Li, Yu

299 3 p.
artikel
96 The mTORC1–G9a–H3K9me2 axis negatively regulates autophagy in fatty acid–induced hepatocellular lipotoxicity Mushtaq, Arjamand

299 3 p.
artikel
97 The pH-sensing Rim101 pathway regulates cell size in budding yeast Shimasawa, Masaru

299 3 p.
artikel
98 The Pseudomonas aeruginosa PAO1 metallo flavoprotein d-2-hydroxyglutarate dehydrogenase requires Zn2+ for substrate orientation and activation Quaye, Joanna A.

299 3 p.
artikel
99 The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling Iwano, Tomohiko

299 3 p.
artikel
100 The role of glycans in the mechanobiology of cancer Purushothaman, Anurag

299 3 p.
artikel
101 The second extracellular domain of connexin 50 is important for in cell adhesion, lens differentiation, and adhesion molecule expression Li, Zhen

299 3 p.
artikel
102 The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins Rosenberg Jr, Eric M.

299 3 p.
artikel
103 The unique N-terminal region of Mycobacterium tuberculosis sigma factor A plays a dominant role in the essential function of this protein Singha, Biplab

299 3 p.
artikel
104 The well-developed actin cytoskeleton and Cthrc1 expression by actin-binding protein drebrin in myofibroblasts promote cardiac and hepatic fibrosis Hironaka, Takanori

299 3 p.
artikel
105 Transcription factor AP-2α activates RNA polymerase III–directed transcription and tumor cell proliferation by controlling expression of c-MYC and p53 Wang, Juan

299 3 p.
artikel
106 Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5 Choi, Eun-Bee

299 3 p.
artikel
107 Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein Pörschke, Marius

299 3 p.
artikel
108 Uncovering Zn2+ as a cofactor of FAD-dependent Pseudomonas aeruginosa PAO1 d-2-hydroxyglutarate dehydrogenase Quaye, Joanna A.

299 3 p.
artikel
109 Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains Santorelli, Daniele

299 3 p.
artikel
110 Untangling interactions in the PAR cell polarity system Dickinson, Daniel J.

299 3 p.
artikel
111 Voltage sensor dynamics of a bacterial voltage-gated sodium channel NavAb reveal three conformational states Han, Shuo

299 3 p.
artikel
112 Yeast display platform with expression of linear peptide epitopes for high-throughput assessment of peptide-MHC-II binding Huisman, Brooke D.

299 3 p.
artikel
                             112 gevonden resultaten
 
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