nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A “biphasic glycosyltransferase high-throughput screen” identifies novel anthraquinone glycosides in the diversification of phenolic natural products
|
Mohideen, F. Ifthiha |
|
|
299 |
3 |
p. |
artikel |
2 |
Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia
|
Zhang, Hao |
|
|
299 |
3 |
p. |
artikel |
3 |
Activation of protein arginine methyltransferase 1 and subsequent extension of moth lifespan is effected by the ROS/JNK/CREB signaling axis
|
Zhang, Xiao-Shuai |
|
|
299 |
3 |
p. |
artikel |
4 |
Aim18p and Aim46p are chalcone isomerase domain–containing mitochondrial hemoproteins in Saccharomyces cerevisiae
|
Schmitz, Jonathan M. |
|
|
299 |
3 |
p. |
artikel |
5 |
Analysis of mammalian circadian clock protein complexes over a circadian cycle
|
Cao, Xuemei |
|
|
299 |
3 |
p. |
artikel |
6 |
An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily
|
Buša, Michal |
|
|
299 |
3 |
p. |
artikel |
7 |
A new electrochemical method that mimics phosphorylation of the core tau peptide K18 enables kinetic and structural analysis of intermediates and assembly
|
Masquelier, Eloise |
|
|
299 |
3 |
p. |
artikel |
8 |
A novel compound targets the feline infectious peritonitis virus nucleocapsid protein and inhibits viral replication in cell culture
|
Mohseni, Nazleen |
|
|
299 |
3 |
p. |
artikel |
9 |
Apo-metallothionein-3 cooperatively forms tightly compact structures under physiological conditions
|
Yuan, Amelia T. |
|
|
299 |
3 |
p. |
artikel |
10 |
A structure-function analysis of chlorophyllase reveals a mechanism for activity regulation dependent on disulfide bonds
|
Jo, Minshik |
|
|
299 |
3 |
p. |
artikel |
11 |
A synthetic organelle approach to probe SNARE-mediated membrane fusion in a bacterial host
|
Ferreras, Soledad |
|
|
299 |
3 |
p. |
artikel |
12 |
Biochemical analysis of SARS-CoV-2 Nsp13 helicase implicated in COVID-19 and factors that regulate its catalytic functions
|
Sommers, Joshua A. |
|
|
299 |
3 |
p. |
artikel |
13 |
Biochemical and structural basis of sialic acid utilization by gut microbes
|
Bell, Andrew |
|
|
299 |
3 |
p. |
artikel |
14 |
Cardiolipin metabolism regulates expression of muscle transcription factor MyoD1 and muscle development
|
Vo, Linh |
|
|
299 |
3 |
p. |
artikel |
15 |
β-cell–selective inhibition of DNA damage response signaling by nitric oxide is associated with an attenuation in glucose uptake
|
Yeo, Chay Teng |
|
|
299 |
3 |
p. |
artikel |
16 |
Characterization of two distinct neutrophil serine protease–binding modes within a Staphylococcus aureus innate immune evasion protein family
|
Gido, Carson D. |
|
|
299 |
3 |
p. |
artikel |
17 |
chi sequences switch the RecBCD helicase–nuclease complex from degradative to replicative modes during the completion of DNA replication
|
Hamilton, Nicklas A. |
|
|
299 |
3 |
p. |
artikel |
18 |
Complex interaction network revealed by mutation of human telomerase ‘insertion in fingers’ and essential N-terminal domains and the telomere protein TPP1
|
Lambert-Lanteigne, Patrick |
|
|
299 |
3 |
p. |
artikel |
19 |
Comprehensive characterization of complex glycosphingolipids in human pancreatic cancer tissues
|
Hořejší, Karel |
|
|
299 |
3 |
p. |
artikel |
20 |
Conformational dynamics control assembly of an extremely long bacteriophage tail tube
|
Agnello, Emily |
|
|
299 |
3 |
p. |
artikel |
21 |
Consensus design and engineering of an efficient and high-yield peptide asparaginyl ligase for protein cyclization and ligation
|
Hemu, Xinya |
|
|
299 |
3 |
p. |
artikel |
22 |
Conservation, abundance, glycosylation profile, and localization of the TSP protein family in Cryptosporidium parvum
|
John, Alan |
|
|
299 |
3 |
p. |
artikel |
23 |
Correction: E3 ubiquitin ligase PARK2, an inhibitor of melanoma cell growth, is repressed by the oncogenic ERK1/2-ELK1 transcriptional axis
|
Montagnani, Valentina |
|
|
299 |
3 |
p. |
artikel |
24 |
Correction: Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation
|
Chaya, Taro |
|
|
299 |
3 |
p. |
artikel |
25 |
Cover
|
|
|
|
299 |
3 |
p. |
artikel |
26 |
Cyclin A–CDK1 suppresses the expression of the CDK1 activator CDC25A to safeguard timely mitotic entry
|
Ng, Lau Yan |
|
|
299 |
3 |
p. |
artikel |
27 |
Depletion of plasma thymidine results in growth retardation and mitochondrial myopathy in mice overexpressing human thymidine phosphorylase
|
Harada, Naomoto |
|
|
299 |
3 |
p. |
artikel |
28 |
Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritis
|
Wu, Yichen |
|
|
299 |
3 |
p. |
artikel |
29 |
Disordered proteins mitigate the temperature dependence of site-specific binding free energies
|
Thole, Joseph F. |
|
|
299 |
3 |
p. |
artikel |
30 |
DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development
|
Zhao, Simin |
|
|
299 |
3 |
p. |
artikel |
31 |
Dynamics of the Synechococcus elongatus cytoskeletal GTPase FtsZ yields mechanistic and evolutionary insight into cyanobacterial and chloroplast FtsZs
|
Porter, Katie J. |
|
|
299 |
3 |
p. |
artikel |
32 |
Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5
|
Guhathakurta, Piyali |
|
|
299 |
3 |
p. |
artikel |
33 |
Ectopic RING activity at the ER membrane differentially impacts ERAD protein quality control pathways
|
Mehrtash, Adrian B. |
|
|
299 |
3 |
p. |
artikel |
34 |
E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide
|
Lee, Su Hyoun |
|
|
299 |
3 |
p. |
artikel |
35 |
Enolpyruvate transferase MurAAA149E, identified during adaptation of Enterococcus faecium to daptomycin, increases stability of MurAA–MurG interaction
|
Zhou, Yue |
|
|
299 |
3 |
p. |
artikel |
36 |
Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2
|
Cross, Frederick R. |
|
|
299 |
3 |
p. |
artikel |
37 |
Exploration of aminoacyl-tRNA synthetases from eukaryotic parasites for drug development
|
Gill, Jasmita |
|
|
299 |
3 |
p. |
artikel |
38 |
Extracellular intersubunit interactions modulate epithelial Na+ channel gating
|
Zhang, Lei |
|
|
299 |
3 |
p. |
artikel |
39 |
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
|
Griffin, Tagan A. |
|
|
299 |
3 |
p. |
artikel |
40 |
Fine spectral tuning of a flavin-binding fluorescent protein for multicolor imaging
|
Nikolaev, Andrey |
|
|
299 |
3 |
p. |
artikel |
41 |
Fitm2 is required for ER homeostasis and normal function of murine liver
|
Bond, Laura M. |
|
|
299 |
3 |
p. |
artikel |
42 |
Functional characterization of Vip3Aa from Bacillus thuringiensis reveals the contributions of specific domains to its insecticidal activity
|
Jiang, Kun |
|
|
299 |
3 |
p. |
artikel |
43 |
Goldilocks calcium concentrations and the regulation of oxidative phosphorylation: Too much, too little, or just right
|
Vilas-Boas, Eloisa A. |
|
|
299 |
3 |
p. |
artikel |
44 |
Group II metabotropic glutamate receptor activation attenuates acid-sensing ion channel currents in rat primary sensory neurons
|
Li, Qing |
|
|
299 |
3 |
p. |
artikel |
45 |
Hepatocyte estrogen sulfotransferase inhibition protects female mice from concanavalin A–induced T cell–mediated hepatitis independent of estrogens
|
Wang, Jingyuan |
|
|
299 |
3 |
p. |
artikel |
46 |
Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX6
|
Dong, Zhangji |
|
|
299 |
3 |
p. |
artikel |
47 |
Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site
|
Petrunak, Elyse M. |
|
|
299 |
3 |
p. |
artikel |
48 |
Human DNA polymerase η promotes RNA-templated error-free repair of DNA double-strand breaks
|
Chakraborty, Anirban |
|
|
299 |
3 |
p. |
artikel |
49 |
Human uridine 5′-monophosphate synthase stores metabolic potential in inactive biomolecular condensates
|
Kim-Holzapfel, Deborah M. |
|
|
299 |
3 |
p. |
artikel |
50 |
Increased angiotensin II coupled with decreased Adra1a expression enhances cardiac hypertrophy in pregnancy-associated hypertensive mice
|
Kim, Jun-Dal |
|
|
299 |
3 |
p. |
artikel |
51 |
Influence of glycoprotein MUC1 on trafficking of the Ca2+-selective ion channels, TRPV5 and TRPV6, and on in vivo calcium homeostasis
|
Al-bataineh, Mohammad M. |
|
|
299 |
3 |
p. |
artikel |
52 |
Inhibiting O-GlcNAcylation impacts p38 and Erk1/2 signaling and perturbs cardiomyocyte hypertrophy
|
Papanicolaou, Kyriakos N. |
|
|
299 |
3 |
p. |
artikel |
53 |
Innate immune cell-intrinsic ketogenesis is dispensable for organismal metabolism and age-related inflammation
|
Goldberg, Emily L. |
|
|
299 |
3 |
p. |
artikel |
54 |
Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in the enteric nervous system
|
Ito, Masatoshi |
|
|
299 |
3 |
p. |
artikel |
55 |
Ion channel chameleons: Switching ion selectivity by alternative splicing
|
Hsu, Allen L. |
|
|
299 |
3 |
p. |
artikel |
56 |
IP3Rs puff along: A SNAPpy dance with IP3 and Ca2+
|
Nakhe, Arya Y. |
|
|
299 |
3 |
p. |
artikel |
57 |
Lanpepsy is a novel lanthanide-binding protein involved in the lanthanide response of the obligate methylotroph Methylobacillus flagellatus
|
Hemmann, Jethro L. |
|
|
299 |
3 |
p. |
artikel |
58 |
Liquid–liquid phase separation of amyloid-β oligomers modulates amyloid fibrils formation
|
Gui, Xinrui |
|
|
299 |
3 |
p. |
artikel |
59 |
Long-chain polyunsaturated lipids associated with responsiveness to anti-PD-1 therapy are colocalized with immune infiltrates in the tumor microenvironment
|
King, Mary E. |
|
|
299 |
3 |
p. |
artikel |
60 |
Loss of fatty acid binding protein 3 ameliorates lipopolysaccharide-induced inflammation and endothelial dysfunction
|
Nguyen, Hien C. |
|
|
299 |
3 |
p. |
artikel |
61 |
Mass spectrometry imaging–based assays for aminotransferase activity reveal a broad substrate spectrum for a previously uncharacterized enzyme
|
de Raad, Markus |
|
|
299 |
3 |
p. |
artikel |
62 |
MceG stabilizes the Mce1 and Mce4 transporters in Mycobacterium tuberculosis
|
Fieweger, Rachael A. |
|
|
299 |
3 |
p. |
artikel |
63 |
Mitochondrial respiration reduces exposure of the nucleus to oxygen
|
Mori, Mateus Prates |
|
|
299 |
3 |
p. |
artikel |
64 |
Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin
|
Amatsu, Sho |
|
|
299 |
3 |
p. |
artikel |
65 |
Multifaceted functions of RNA-binding protein vigilin in gene silencing, genome stability, and autism-related disorders
|
Mushtaq, Arjamand |
|
|
299 |
3 |
p. |
artikel |
66 |
Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation
|
Campolo, Nicolás |
|
|
299 |
3 |
p. |
artikel |
67 |
Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling
|
Sloan, Douglas C. |
|
|
299 |
3 |
p. |
artikel |
68 |
O-GlcNAc transferase modulates the cellular endocytosis machinery by controlling the formation of clathrin-coated pits
|
Rahmani, Sadia |
|
|
299 |
3 |
p. |
artikel |
69 |
Oral arsenic administration to humanized UDP- glucuronosyltransferase 1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR
|
Yang, Xiaojing |
|
|
299 |
3 |
p. |
artikel |
70 |
Oxidation modulates LINGO2-induced inactivation of large conductance, Ca2+-activated potassium channels
|
Dudem, Srikanth |
|
|
299 |
3 |
p. |
artikel |
71 |
Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase η and reduces DNA synthesis fidelity
|
Chang, Caleb |
|
|
299 |
3 |
p. |
artikel |
72 |
Protein tyrosine phosphatase 69D is a substrate of protein O-mannosyltransferases 1-2 that is required for the wiring of sensory axons in Drosophila
|
Monagas-Valentin, Pedro |
|
|
299 |
3 |
p. |
artikel |
73 |
Pseudophosphorylation of Arabidopsis jasmonate biosynthesis enzyme lipoxygenase 2 via mutation of Ser600 inhibits enzyme activity
|
Kaur, Diljot |
|
|
299 |
3 |
p. |
artikel |
74 |
Receptor-binding domain of SARS-CoV-2 is a functional αv-integrin agonist
|
Norris, Emma G. |
|
|
299 |
3 |
p. |
artikel |
75 |
Residues E53, L55, H59, and G70 of the cellular receptor protein Tva mediate cell binding and entry of the novel subgroup K avian leukosis virus
|
Li, Xinyi |
|
|
299 |
3 |
p. |
artikel |
76 |
RhoA rescues cardiac senescence by regulating Parkin-mediated mitophagy
|
Soh, Joanne Ern Chi |
|
|
299 |
3 |
p. |
artikel |
77 |
Risk modeling of single-cell transcriptomes reveals the heterogeneity of immune infiltration in hepatocellular carcinoma
|
Wang, Lu |
|
|
299 |
3 |
p. |
artikel |
78 |
Rubredoxin 1 promotes the proper folding of D1 and is not required for heme b 559 assembly in Chlamydomonas photosystem II
|
Calderon, Robert H. |
|
|
299 |
3 |
p. |
artikel |
79 |
SARS-CoV-2–encoded ORF8 protein possesses complement inhibitory properties
|
Kumar, Jitendra |
|
|
299 |
3 |
p. |
artikel |
80 |
Saturated fatty acid– and/or monounsaturated fatty acid–containing phosphatidic acids selectively interact with heat shock protein 27
|
Yachida, Naoto |
|
|
299 |
3 |
p. |
artikel |
81 |
Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation
|
Barbieri, Guido |
|
|
299 |
3 |
p. |
artikel |
82 |
Serine/threonine-protein kinase STK24 induces tumorigenesis by regulating the STAT3/VEGFA signaling pathway
|
Lai, Senyan |
|
|
299 |
3 |
p. |
artikel |
83 |
Staphylococcal Periscope proteins Aap, SasG, and Pls project noncanonical legume-like lectin adhesin domains from the bacterial surface
|
Clark, Laura C. |
|
|
299 |
3 |
p. |
artikel |
84 |
Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease
|
Noske, Gabriela Dias |
|
|
299 |
3 |
p. |
artikel |
85 |
Structural insights into the recognition of telomeric variant repeat TTGGGG by broad-complex, tramtrack and bric-à-brac - zinc finger protein ZBTB10
|
Wang, Suman |
|
|
299 |
3 |
p. |
artikel |
86 |
Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors
|
Liu, Shenping |
|
|
299 |
3 |
p. |
artikel |
87 |
Structure of VanS from vancomycin-resistant enterococci: A sensor kinase with weak ATP binding
|
Grasty, Kimberly C. |
|
|
299 |
3 |
p. |
artikel |
88 |
Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code
|
Herrmann, Eric |
|
|
299 |
3 |
p. |
artikel |
89 |
The clathrin adaptor complex-1 and Rab12 regulate post-golgi trafficking of WT epidermal growth factor receptor (EGFR)
|
Wang, Jinhui |
|
|
299 |
3 |
p. |
artikel |
90 |
The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease
|
Baek, Judy |
|
|
299 |
3 |
p. |
artikel |
91 |
The Dengue virus protease NS2B3 cleaves cyclic GMP-AMP synthase to suppress cGAS activation
|
Bhattacharya, Madhurima |
|
|
299 |
3 |
p. |
artikel |
92 |
The β-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning
|
Gogar, Rajleen K. |
|
|
299 |
3 |
p. |
artikel |
93 |
The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes
|
Song, Liu |
|
|
299 |
3 |
p. |
artikel |
94 |
The Mfd protein is the transcription-repair coupling factor (TRCF) in Mycobacterium smegmatis
|
Adebali, Ogun |
|
|
299 |
3 |
p. |
artikel |
95 |
The mTORC2/AKT/VCP axis is associated with quality control of the stalled translation of poly(GR) dipeptide repeats in C9-ALS/FTD
|
Li, Yu |
|
|
299 |
3 |
p. |
artikel |
96 |
The mTORC1–G9a–H3K9me2 axis negatively regulates autophagy in fatty acid–induced hepatocellular lipotoxicity
|
Mushtaq, Arjamand |
|
|
299 |
3 |
p. |
artikel |
97 |
The pH-sensing Rim101 pathway regulates cell size in budding yeast
|
Shimasawa, Masaru |
|
|
299 |
3 |
p. |
artikel |
98 |
The Pseudomonas aeruginosa PAO1 metallo flavoprotein d-2-hydroxyglutarate dehydrogenase requires Zn2+ for substrate orientation and activation
|
Quaye, Joanna A. |
|
|
299 |
3 |
p. |
artikel |
99 |
The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling
|
Iwano, Tomohiko |
|
|
299 |
3 |
p. |
artikel |
100 |
The role of glycans in the mechanobiology of cancer
|
Purushothaman, Anurag |
|
|
299 |
3 |
p. |
artikel |
101 |
The second extracellular domain of connexin 50 is important for in cell adhesion, lens differentiation, and adhesion molecule expression
|
Li, Zhen |
|
|
299 |
3 |
p. |
artikel |
102 |
The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins
|
Rosenberg Jr, Eric M. |
|
|
299 |
3 |
p. |
artikel |
103 |
The unique N-terminal region of Mycobacterium tuberculosis sigma factor A plays a dominant role in the essential function of this protein
|
Singha, Biplab |
|
|
299 |
3 |
p. |
artikel |
104 |
The well-developed actin cytoskeleton and Cthrc1 expression by actin-binding protein drebrin in myofibroblasts promote cardiac and hepatic fibrosis
|
Hironaka, Takanori |
|
|
299 |
3 |
p. |
artikel |
105 |
Transcription factor AP-2α activates RNA polymerase III–directed transcription and tumor cell proliferation by controlling expression of c-MYC and p53
|
Wang, Juan |
|
|
299 |
3 |
p. |
artikel |
106 |
Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5
|
Choi, Eun-Bee |
|
|
299 |
3 |
p. |
artikel |
107 |
Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein
|
Pörschke, Marius |
|
|
299 |
3 |
p. |
artikel |
108 |
Uncovering Zn2+ as a cofactor of FAD-dependent Pseudomonas aeruginosa PAO1 d-2-hydroxyglutarate dehydrogenase
|
Quaye, Joanna A. |
|
|
299 |
3 |
p. |
artikel |
109 |
Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains
|
Santorelli, Daniele |
|
|
299 |
3 |
p. |
artikel |
110 |
Untangling interactions in the PAR cell polarity system
|
Dickinson, Daniel J. |
|
|
299 |
3 |
p. |
artikel |
111 |
Voltage sensor dynamics of a bacterial voltage-gated sodium channel NavAb reveal three conformational states
|
Han, Shuo |
|
|
299 |
3 |
p. |
artikel |
112 |
Yeast display platform with expression of linear peptide epitopes for high-throughput assessment of peptide-MHC-II binding
|
Huisman, Brooke D. |
|
|
299 |
3 |
p. |
artikel |