nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2
|
Horton, John R. |
|
|
299 |
2 |
p. |
artikel |
2 |
ADR3, a next generation i-body to human RANKL, inhibits osteoclast formation and bone resorption
|
Qiu, Heng |
|
|
299 |
2 |
p. |
artikel |
3 |
AepG is a glucuronosyltransferase involved in acidic exopolysaccharide synthesis and contributes to environmental adaptation of Haloarcula hispanica
|
Pei, Caixia |
|
|
299 |
2 |
p. |
artikel |
4 |
Agonist-controlled competition of RAR and VDR nuclear receptors for heterodimerization with RXR is manifested in their DNA binding
|
Rehó, Bálint |
|
|
299 |
2 |
p. |
artikel |
5 |
A liquid-to-solid phase transition of Cu/Zn superoxide dismutase 1 initiated by oxidation and disease mutation
|
Gu, Siyu |
|
|
299 |
2 |
p. |
artikel |
6 |
A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity
|
Fare, Charlotte M. |
|
|
299 |
2 |
p. |
artikel |
7 |
Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control
|
Wang, Wei |
|
|
299 |
2 |
p. |
artikel |
8 |
An optimized Western blot assay provides a comprehensive assessment of the physiological endoproteolytic processing of the prion protein
|
Vanni, Ilaria |
|
|
299 |
2 |
p. |
artikel |
9 |
A novel agonist with homobivalent single-domain antibodies that bind the FGF receptor 1 domain III functions as an FGF2 ligand
|
Yonehara, Ryo |
|
|
299 |
2 |
p. |
artikel |
10 |
An RNA stem-loop functions in conjunction with an upstream open reading frame to direct preferential translation in the integrated stress response
|
Amin, Parth H. |
|
|
299 |
2 |
p. |
artikel |
11 |
A solution structure analysis reveals a bent collagen triple helix in the complement activation recognition molecule mannan-binding lectin
|
Iqbal, Hina |
|
|
299 |
2 |
p. |
artikel |
12 |
Assembly chaperone Nas6 selectively destabilizes 26S proteasomes with defective regulatory particle-core particle interfaces
|
Warnock, Jennifer L. |
|
|
299 |
2 |
p. |
artikel |
13 |
Candidalysin: Connecting the pore forming mechanism of this virulence factor to its immunostimulatory properties
|
Russell, Charles M. |
|
|
299 |
2 |
p. |
artikel |
14 |
Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells
|
Hsu, Jake |
|
|
299 |
2 |
p. |
artikel |
15 |
Charge neutralization of the active site glutamates does not limit substrate binding and transport by small multidrug resistance transporter EmrE
|
Spreacker, Peyton J. |
|
|
299 |
2 |
p. |
artikel |
16 |
Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins
|
Li, Jian |
|
|
299 |
2 |
p. |
artikel |
17 |
Comprehensive analysis of RNA-binding protein SRSF2-dependent alternative splicing signature in malignant proliferation of colorectal carcinoma
|
Liu, Weizhen |
|
|
299 |
2 |
p. |
artikel |
18 |
Conformational interdomain flexibility in a bacterial α-isopropylmalate synthase is necessary for leucine biosynthesis
|
Bai, Yu |
|
|
299 |
2 |
p. |
artikel |
19 |
Correction: AMP-activated protein kinase α1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation
|
Zhang, Miao |
|
|
299 |
2 |
p. |
artikel |
20 |
Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement
|
Jensen, Rasmus K. |
|
|
299 |
2 |
p. |
artikel |
21 |
Correction: Interdomain interactions dictate the function of the Candida albicans Hsp110 protein Msi3
|
Li, Hongtao |
|
|
299 |
2 |
p. |
artikel |
22 |
Correction: Phagocytosis mediated by scavenger receptor class BI promotes macrophage transition during skeletal muscle regeneration
|
Zhang, Jing |
|
|
299 |
2 |
p. |
artikel |
23 |
Cover
|
|
|
|
299 |
2 |
p. |
artikel |
24 |
Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding
|
Nakanishi, Atsuko |
|
|
299 |
2 |
p. |
artikel |
25 |
Cryo-EM structure of the plant nitrate transporter AtCLCa reveals characteristics of the anion-binding site and the ATP-binding pocket
|
He, Jin |
|
|
299 |
2 |
p. |
artikel |
26 |
Disruption of the interaction between mutationally activated Gαq and Gβγ attenuates aberrant signaling
|
Aumiller, Jenna L. |
|
|
299 |
2 |
p. |
artikel |
27 |
Dissociation of inositol 1,4,5-trisphosphate from IP3 receptors contributes to termination of Ca2+ puffs
|
Smith, Holly A. |
|
|
299 |
2 |
p. |
artikel |
28 |
Dynamic cycling with a unique Hsp90/Hsp70-dependent chaperone machinery and GAPDH is needed for heme insertion and activation of neuronal NO synthase
|
Morishima, Yoshihiro |
|
|
299 |
2 |
p. |
artikel |
29 |
Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method
|
Hayashida, Ryota |
|
|
299 |
2 |
p. |
artikel |
30 |
Endoplasmic reticulum protein BIK binds to and inhibits mitochondria-localized antiapoptotic proteins
|
Osterlund, Elizabeth J. |
|
|
299 |
2 |
p. |
artikel |
31 |
Ensembles of human myosin-19 bound to calmodulin and regulatory light chain RLC12B drive multimicron transport
|
Pollard, Luther W. |
|
|
299 |
2 |
p. |
artikel |
32 |
Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase Polζ
|
McPherson, Kerry Silva |
|
|
299 |
2 |
p. |
artikel |
33 |
Exosomes are involved in iron transport from human blood–brain barrier endothelial cells and are modified by endothelial cell iron status
|
Palsa, Kondaiah |
|
|
299 |
2 |
p. |
artikel |
34 |
Expanded in vivo substrate profile of the yeast N-terminal acetyltransferase NatC
|
Van Damme, Petra |
|
|
299 |
2 |
p. |
artikel |
35 |
Extracellular chaperone networks and the export of J-domain proteins
|
Braun, Janice E.A. |
|
|
299 |
2 |
p. |
artikel |
36 |
5-Formyltetrahydrofolate promotes conformational remodeling in a methylenetetrahydrofolate reductase active site and inhibits its activity
|
Yamada, Kazuhiro |
|
|
299 |
2 |
p. |
artikel |
37 |
HECT domain interaction with ubiquitin binding sites on Tsg101-UEV controls HIV-1 egress, maturation, and infectivity
|
Nyenhuis, David A. |
|
|
299 |
2 |
p. |
artikel |
38 |
Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice
|
Wang, Xiaoyan |
|
|
299 |
2 |
p. |
artikel |
39 |
hERG1 channel subunit composition mediates proton inhibition of rapid delayed rectifier potassium current (I Kr) in cardiomyocytes derived from hiPSCs
|
Ukachukwu, Chiamaka U. |
|
|
299 |
2 |
p. |
artikel |
40 |
Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration
|
Namitz, Kevin E.W. |
|
|
299 |
2 |
p. |
artikel |
41 |
How T118M peripheral myelin protein 22 predisposes humans to Charcot–Marie–Tooth disease
|
Stefanski, Katherine M. |
|
|
299 |
2 |
p. |
artikel |
42 |
HSP70 mediates a crosstalk between the estrogen and the heat shock response pathways
|
Silveira, Maruhen Amir Datsch |
|
|
299 |
2 |
p. |
artikel |
43 |
Identification and structural analysis of a carbohydrate-binding module specific to alginate, a representative of a new family, CBM96
|
Ji, Shiqi |
|
|
299 |
2 |
p. |
artikel |
44 |
Influenza virus and pneumococcal neuraminidases enhance catalysis by similar yet distinct sialic acid–binding strategies
|
Klenow, Laura |
|
|
299 |
2 |
p. |
artikel |
45 |
Intracellular zinc protects Kv7 K+ channels from Ca2+/calmodulin-mediated inhibition
|
Yang, Xinhe |
|
|
299 |
2 |
p. |
artikel |
46 |
Kinetochore-microtubule attachment in human cells is regulated by the interaction of a conserved motif of Ska1 with EB1
|
Radhakrishnan, Renjith M. |
|
|
299 |
2 |
p. |
artikel |
47 |
Limb blastema formation: How much do we know at a genetic and epigenetic level?
|
Min, Sangwon |
|
|
299 |
2 |
p. |
artikel |
48 |
Loss of small GTPase Rab7 activation in prion infection negatively affects a feedback loop regulating neuronal cholesterol metabolism
|
Cherry, Pearl |
|
|
299 |
2 |
p. |
artikel |
49 |
Measurement of FGFR3 signaling at the cell membrane via total internal reflection fluorescence microscopy to compare the activation of FGFR3 mutants
|
Hartl, Ingrid |
|
|
299 |
2 |
p. |
artikel |
50 |
Measurements of Na+-occluded intermediates during the catalytic cycle of the Na+/K+-ATPase provide novel insights into the mechanism of Na+ transport
|
Faraj, Santiago E. |
|
|
299 |
2 |
p. |
artikel |
51 |
Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity
|
Chen, Xiao-Ru |
|
|
299 |
2 |
p. |
artikel |
52 |
Membrane skeleton hyperstability due to a novel alternatively spliced 4.1R can account for ellipsoidal camelid red cells with decreased deformability
|
Chen, Yuqi |
|
|
299 |
2 |
p. |
artikel |
53 |
Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation
|
Ikizawa, Takeshi |
|
|
299 |
2 |
p. |
artikel |
54 |
Mitochondria-localized lncRNA HITT inhibits fusion by attenuating formation of mitofusin-2 homotypic or heterotypic complexes
|
Wang, Xingwen |
|
|
299 |
2 |
p. |
artikel |
55 |
Molecular dynamics simulations of the calmodulin-induced α-helix in the SK2 calcium-gated potassium ion channel
|
Ramis, Rafael |
|
|
299 |
2 |
p. |
artikel |
56 |
Monitoring mitochondrial translation by pulse SILAC
|
Imami, Koshi |
|
|
299 |
2 |
p. |
artikel |
57 |
Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 2
|
Liu, Xiao |
|
|
299 |
2 |
p. |
artikel |
58 |
Neurodegeneration risk factor, EIF2AK3 (PERK), influences tau protein aggregation
|
Park, Goonho |
|
|
299 |
2 |
p. |
artikel |
59 |
Nucleotide addition and cleavage by RNA polymerase II: Coordination of two catalytic reactions using a single active site
|
Unarta, Ilona Christy |
|
|
299 |
2 |
p. |
artikel |
60 |
Oncogenic RAS promotes MYC protein stability by upregulating the expression of the inhibitor of apoptosis protein family member Survivin
|
Chang, Wen-Hsuan |
|
|
299 |
2 |
p. |
artikel |
61 |
Overexpression of Pdx1, reduction of p53, or deletion of CHOP attenuates pancreas hypoplasia in mice with pancreas-specific O-GlcNAc transferase deletion
|
Wong, Alicia |
|
|
299 |
2 |
p. |
artikel |
62 |
Pab1 acetylation at K131 decreases stress granule formation in Saccharomyces cerevisiae
|
Sivananthan, Sangavi |
|
|
299 |
2 |
p. |
artikel |
63 |
Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin
|
Ramirez, Maria Paz |
|
|
299 |
2 |
p. |
artikel |
64 |
pH profiles of 3-chymotrypsin-like protease (3CLpro) from SARS-CoV-2 elucidate its catalytic mechanism and a histidine residue critical for activity
|
Al Adem, Kenana |
|
|
299 |
2 |
p. |
artikel |
65 |
Polo-like kinase 1 (PLK1) O-GlcNAcylation is essential for dividing mammalian cells and inhibits uterine carcinoma
|
Yan, Sheng |
|
|
299 |
2 |
p. |
artikel |
66 |
Positive charge in the K-loop of the kinesin-3 motor KIF1A regulates superprocessivity by enhancing microtubule affinity in the one-head–bound state
|
Zaniewski, Taylor M. |
|
|
299 |
2 |
p. |
artikel |
67 |
Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function
|
Kearney, Patrick J. |
|
|
299 |
2 |
p. |
artikel |
68 |
Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis
|
Kondolf, Hannah C. |
|
|
299 |
2 |
p. |
artikel |
69 |
RanBP9 controls the oligomeric state of CTLH complex assemblies
|
van gen Hassend, Pia Maria |
|
|
299 |
2 |
p. |
artikel |
70 |
Regulation and function of the mammalian tricarboxylic acid cycle
|
Arnold, Paige K. |
|
|
299 |
2 |
p. |
artikel |
71 |
Regulation of cell size and Wee1 kinase by elevated levels of the cell cycle regulatory protein kinase Cdr2
|
Berg, Rachel A. |
|
|
299 |
2 |
p. |
artikel |
72 |
Regulatory role of endoplasmic reticulum resident chaperone protein ERp29 in anti-murine β-coronavirus host cell response
|
Bose, Abhishek |
|
|
299 |
2 |
p. |
artikel |
73 |
Role of omega-3 endocannabinoids in the modulation of T-cell activity in a multiple sclerosis experimental autoimmune encephalomyelitis (EAE) model
|
Kim, Justin S. |
|
|
299 |
2 |
p. |
artikel |
74 |
Smad2Δexon3 and Smad3 have distinct properties in signal transmission leading to TGF-β–induced cell motility
|
Yokoyama, Takashi |
|
|
299 |
2 |
p. |
artikel |
75 |
SPECC1L binds the myosin phosphatase complex MYPT1/PP1β and can regulate its distribution between microtubules and filamentous actin
|
Mehta, Virja |
|
|
299 |
2 |
p. |
artikel |
76 |
Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition
|
Robert, Charly |
|
|
299 |
2 |
p. |
artikel |
77 |
Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia
|
Ren, Ren |
|
|
299 |
2 |
p. |
artikel |
78 |
Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn2+ coordination and substrate binding
|
Du, Xueqing |
|
|
299 |
2 |
p. |
artikel |
79 |
Targeting peroxisomal fatty acid oxidation improves hepatic steatosis and insulin resistance in obese mice
|
Yao, Haoya |
|
|
299 |
2 |
p. |
artikel |
80 |
αβ T-cell receptor recognition of self-phosphatidylinositol presented by CD1b
|
Farquhar, Rachel |
|
|
299 |
2 |
p. |
artikel |
81 |
TGF-β1 suppresses the T-cell response in teleost fish by initiating Smad3- and Foxp3-mediated transcriptional networks
|
Zhang, Qian |
|
|
299 |
2 |
p. |
artikel |
82 |
The impact of glucose on mitochondria and life span is determined by the integrity of proline catabolism in Caenorhabditis elegans
|
Feng, Xi |
|
|
299 |
2 |
p. |
artikel |
83 |
The 14-3-3γ isoform binds to and regulates the localization of endoplasmic reticulum (ER) membrane protein TMCC3 for the reticular network of the ER
|
Suhda, Saihas |
|
|
299 |
2 |
p. |
artikel |
84 |
The MRN complex and topoisomerase IIIa–RMI1/2 synchronize DNA resection motor proteins
|
Soniat, Michael M. |
|
|
299 |
2 |
p. |
artikel |
85 |
The nematode α-catenin ortholog, HMP1, has an extended α-helix when bound to actin filaments
|
Rangarajan, Erumbi S. |
|
|
299 |
2 |
p. |
artikel |
86 |
The NTPase activity of the double FYVE domain–containing protein 1 regulates lipid droplet metabolism
|
Ismail, V.A. |
|
|
299 |
2 |
p. |
artikel |
87 |
The penultimate step of proteasomal ATPase assembly is mediated by a switch dependent on the chaperone Nas2
|
Sekaran, Suganya |
|
|
299 |
2 |
p. |
artikel |
88 |
The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly
|
Wang, Feng |
|
|
299 |
2 |
p. |
artikel |
89 |
The store-operated Ca2+ channel Orai1α is required for agonist-evoked NF-κB activation by a mechanism dependent on PKCβ2
|
Nieto-Felipe, Joel |
|
|
299 |
2 |
p. |
artikel |
90 |
The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes
|
Higgins, Cassandra B. |
|
|
299 |
2 |
p. |
artikel |
91 |
Two Trk/Ktr/HKT-type potassium transporters, TrkG and TrkH, perform distinct functions in Escherichia coli K-12
|
Tanudjaja, Ellen |
|
|
299 |
2 |
p. |
artikel |
92 |
Untranslated regions of brain-derived neurotrophic factor mRNA control its translatability and subcellular localization
|
Lekk, Ingrid |
|
|
299 |
2 |
p. |
artikel |
93 |
Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry
|
Arang, Nadia |
|
|
299 |
2 |
p. |
artikel |