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                             93 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2 Horton, John R.

299 2 p.
artikel
2 ADR3, a next generation i-body to human RANKL, inhibits osteoclast formation and bone resorption Qiu, Heng

299 2 p.
artikel
3 AepG is a glucuronosyltransferase involved in acidic exopolysaccharide synthesis and contributes to environmental adaptation of Haloarcula hispanica Pei, Caixia

299 2 p.
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4 Agonist-controlled competition of RAR and VDR nuclear receptors for heterodimerization with RXR is manifested in their DNA binding Rehó, Bálint

299 2 p.
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5 A liquid-to-solid phase transition of Cu/Zn superoxide dismutase 1 initiated by oxidation and disease mutation Gu, Siyu

299 2 p.
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6 A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity Fare, Charlotte M.

299 2 p.
artikel
7 Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control Wang, Wei

299 2 p.
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8 An optimized Western blot assay provides a comprehensive assessment of the physiological endoproteolytic processing of the prion protein Vanni, Ilaria

299 2 p.
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9 A novel agonist with homobivalent single-domain antibodies that bind the FGF receptor 1 domain III functions as an FGF2 ligand Yonehara, Ryo

299 2 p.
artikel
10 An RNA stem-loop functions in conjunction with an upstream open reading frame to direct preferential translation in the integrated stress response Amin, Parth H.

299 2 p.
artikel
11 A solution structure analysis reveals a bent collagen triple helix in the complement activation recognition molecule mannan-binding lectin Iqbal, Hina

299 2 p.
artikel
12 Assembly chaperone Nas6 selectively destabilizes 26S proteasomes with defective regulatory particle-core particle interfaces Warnock, Jennifer L.

299 2 p.
artikel
13 Candidalysin: Connecting the pore forming mechanism of this virulence factor to its immunostimulatory properties Russell, Charles M.

299 2 p.
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14 Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells Hsu, Jake

299 2 p.
artikel
15 Charge neutralization of the active site glutamates does not limit substrate binding and transport by small multidrug resistance transporter EmrE Spreacker, Peyton J.

299 2 p.
artikel
16 Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins Li, Jian

299 2 p.
artikel
17 Comprehensive analysis of RNA-binding protein SRSF2-dependent alternative splicing signature in malignant proliferation of colorectal carcinoma Liu, Weizhen

299 2 p.
artikel
18 Conformational interdomain flexibility in a bacterial α-isopropylmalate synthase is necessary for leucine biosynthesis Bai, Yu

299 2 p.
artikel
19 Correction: AMP-activated protein kinase α1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation Zhang, Miao

299 2 p.
artikel
20 Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement Jensen, Rasmus K.

299 2 p.
artikel
21 Correction: Interdomain interactions dictate the function of the Candida albicans Hsp110 protein Msi3 Li, Hongtao

299 2 p.
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22 Correction: Phagocytosis mediated by scavenger receptor class BI promotes macrophage transition during skeletal muscle regeneration Zhang, Jing

299 2 p.
artikel
23 Cover
299 2 p.
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24 Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding Nakanishi, Atsuko

299 2 p.
artikel
25 Cryo-EM structure of the plant nitrate transporter AtCLCa reveals characteristics of the anion-binding site and the ATP-binding pocket He, Jin

299 2 p.
artikel
26 Disruption of the interaction between mutationally activated Gαq and Gβγ attenuates aberrant signaling Aumiller, Jenna L.

299 2 p.
artikel
27 Dissociation of inositol 1,4,5-trisphosphate from IP3 receptors contributes to termination of Ca2+ puffs Smith, Holly A.

299 2 p.
artikel
28 Dynamic cycling with a unique Hsp90/Hsp70-dependent chaperone machinery and GAPDH is needed for heme insertion and activation of neuronal NO synthase Morishima, Yoshihiro

299 2 p.
artikel
29 Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method Hayashida, Ryota

299 2 p.
artikel
30 Endoplasmic reticulum protein BIK binds to and inhibits mitochondria-localized antiapoptotic proteins Osterlund, Elizabeth J.

299 2 p.
artikel
31 Ensembles of human myosin-19 bound to calmodulin and regulatory light chain RLC12B drive multimicron transport Pollard, Luther W.

299 2 p.
artikel
32 Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase Polζ McPherson, Kerry Silva

299 2 p.
artikel
33 Exosomes are involved in iron transport from human blood–brain barrier endothelial cells and are modified by endothelial cell iron status Palsa, Kondaiah

299 2 p.
artikel
34 Expanded in vivo substrate profile of the yeast N-terminal acetyltransferase NatC Van Damme, Petra

299 2 p.
artikel
35 Extracellular chaperone networks and the export of J-domain proteins Braun, Janice E.A.

299 2 p.
artikel
36 5-Formyltetrahydrofolate promotes conformational remodeling in a methylenetetrahydrofolate reductase active site and inhibits its activity Yamada, Kazuhiro

299 2 p.
artikel
37 HECT domain interaction with ubiquitin binding sites on Tsg101-UEV controls HIV-1 egress, maturation, and infectivity Nyenhuis, David A.

299 2 p.
artikel
38 Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice Wang, Xiaoyan

299 2 p.
artikel
39 hERG1 channel subunit composition mediates proton inhibition of rapid delayed rectifier potassium current (I Kr) in cardiomyocytes derived from hiPSCs Ukachukwu, Chiamaka U.

299 2 p.
artikel
40 Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration Namitz, Kevin E.W.

299 2 p.
artikel
41 How T118M peripheral myelin protein 22 predisposes humans to Charcot–Marie–Tooth disease Stefanski, Katherine M.

299 2 p.
artikel
42 HSP70 mediates a crosstalk between the estrogen and the heat shock response pathways Silveira, Maruhen Amir Datsch

299 2 p.
artikel
43 Identification and structural analysis of a carbohydrate-binding module specific to alginate, a representative of a new family, CBM96 Ji, Shiqi

299 2 p.
artikel
44 Influenza virus and pneumococcal neuraminidases enhance catalysis by similar yet distinct sialic acid–binding strategies Klenow, Laura

299 2 p.
artikel
45 Intracellular zinc protects Kv7 K+ channels from Ca2+/calmodulin-mediated inhibition Yang, Xinhe

299 2 p.
artikel
46 Kinetochore-microtubule attachment in human cells is regulated by the interaction of a conserved motif of Ska1 with EB1 Radhakrishnan, Renjith M.

299 2 p.
artikel
47 Limb blastema formation: How much do we know at a genetic and epigenetic level? Min, Sangwon

299 2 p.
artikel
48 Loss of small GTPase Rab7 activation in prion infection negatively affects a feedback loop regulating neuronal cholesterol metabolism Cherry, Pearl

299 2 p.
artikel
49 Measurement of FGFR3 signaling at the cell membrane via total internal reflection fluorescence microscopy to compare the activation of FGFR3 mutants Hartl, Ingrid

299 2 p.
artikel
50 Measurements of Na+-occluded intermediates during the catalytic cycle of the Na+/K+-ATPase provide novel insights into the mechanism of Na+ transport Faraj, Santiago E.

299 2 p.
artikel
51 Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity Chen, Xiao-Ru

299 2 p.
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52 Membrane skeleton hyperstability due to a novel alternatively spliced 4.1R can account for ellipsoidal camelid red cells with decreased deformability Chen, Yuqi

299 2 p.
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53 Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation Ikizawa, Takeshi

299 2 p.
artikel
54 Mitochondria-localized lncRNA HITT inhibits fusion by attenuating formation of mitofusin-2 homotypic or heterotypic complexes Wang, Xingwen

299 2 p.
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55 Molecular dynamics simulations of the calmodulin-induced α-helix in the SK2 calcium-gated potassium ion channel Ramis, Rafael

299 2 p.
artikel
56 Monitoring mitochondrial translation by pulse SILAC Imami, Koshi

299 2 p.
artikel
57 Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 2 Liu, Xiao

299 2 p.
artikel
58 Neurodegeneration risk factor, EIF2AK3 (PERK), influences tau protein aggregation Park, Goonho

299 2 p.
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59 Nucleotide addition and cleavage by RNA polymerase II: Coordination of two catalytic reactions using a single active site Unarta, Ilona Christy

299 2 p.
artikel
60 Oncogenic RAS promotes MYC protein stability by upregulating the expression of the inhibitor of apoptosis protein family member Survivin Chang, Wen-Hsuan

299 2 p.
artikel
61 Overexpression of Pdx1, reduction of p53, or deletion of CHOP attenuates pancreas hypoplasia in mice with pancreas-specific O-GlcNAc transferase deletion Wong, Alicia

299 2 p.
artikel
62 Pab1 acetylation at K131 decreases stress granule formation in Saccharomyces cerevisiae Sivananthan, Sangavi

299 2 p.
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63 Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin Ramirez, Maria Paz

299 2 p.
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64 pH profiles of 3-chymotrypsin-like protease (3CLpro) from SARS-CoV-2 elucidate its catalytic mechanism and a histidine residue critical for activity Al Adem, Kenana

299 2 p.
artikel
65 Polo-like kinase 1 (PLK1) O-GlcNAcylation is essential for dividing mammalian cells and inhibits uterine carcinoma Yan, Sheng

299 2 p.
artikel
66 Positive charge in the K-loop of the kinesin-3 motor KIF1A regulates superprocessivity by enhancing microtubule affinity in the one-head–bound state Zaniewski, Taylor M.

299 2 p.
artikel
67 Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function Kearney, Patrick J.

299 2 p.
artikel
68 Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis Kondolf, Hannah C.

299 2 p.
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69 RanBP9 controls the oligomeric state of CTLH complex assemblies van gen Hassend, Pia Maria

299 2 p.
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70 Regulation and function of the mammalian tricarboxylic acid cycle Arnold, Paige K.

299 2 p.
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71 Regulation of cell size and Wee1 kinase by elevated levels of the cell cycle regulatory protein kinase Cdr2 Berg, Rachel A.

299 2 p.
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72 Regulatory role of endoplasmic reticulum resident chaperone protein ERp29 in anti-murine β-coronavirus host cell response Bose, Abhishek

299 2 p.
artikel
73 Role of omega-3 endocannabinoids in the modulation of T-cell activity in a multiple sclerosis experimental autoimmune encephalomyelitis (EAE) model Kim, Justin S.

299 2 p.
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74 Smad2Δexon3 and Smad3 have distinct properties in signal transmission leading to TGF-β–induced cell motility Yokoyama, Takashi

299 2 p.
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75 SPECC1L binds the myosin phosphatase complex MYPT1/PP1β and can regulate its distribution between microtubules and filamentous actin Mehta, Virja

299 2 p.
artikel
76 Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition Robert, Charly

299 2 p.
artikel
77 Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia Ren, Ren

299 2 p.
artikel
78 Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn2+ coordination and substrate binding Du, Xueqing

299 2 p.
artikel
79 Targeting peroxisomal fatty acid oxidation improves hepatic steatosis and insulin resistance in obese mice Yao, Haoya

299 2 p.
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80 αβ T-cell receptor recognition of self-phosphatidylinositol presented by CD1b Farquhar, Rachel

299 2 p.
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81 TGF-β1 suppresses the T-cell response in teleost fish by initiating Smad3- and Foxp3-mediated transcriptional networks Zhang, Qian

299 2 p.
artikel
82 The impact of glucose on mitochondria and life span is determined by the integrity of proline catabolism in Caenorhabditis elegans Feng, Xi

299 2 p.
artikel
83 The 14-3-3γ isoform binds to and regulates the localization of endoplasmic reticulum (ER) membrane protein TMCC3 for the reticular network of the ER Suhda, Saihas

299 2 p.
artikel
84 The MRN complex and topoisomerase IIIa–RMI1/2 synchronize DNA resection motor proteins Soniat, Michael M.

299 2 p.
artikel
85 The nematode α-catenin ortholog, HMP1, has an extended α-helix when bound to actin filaments Rangarajan, Erumbi S.

299 2 p.
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86 The NTPase activity of the double FYVE domain–containing protein 1 regulates lipid droplet metabolism Ismail, V.A.

299 2 p.
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87 The penultimate step of proteasomal ATPase assembly is mediated by a switch dependent on the chaperone Nas2 Sekaran, Suganya

299 2 p.
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88 The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly Wang, Feng

299 2 p.
artikel
89 The store-operated Ca2+ channel Orai1α is required for agonist-evoked NF-κB activation by a mechanism dependent on PKCβ2 Nieto-Felipe, Joel

299 2 p.
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90 The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes Higgins, Cassandra B.

299 2 p.
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91 Two Trk/Ktr/HKT-type potassium transporters, TrkG and TrkH, perform distinct functions in Escherichia coli K-12 Tanudjaja, Ellen

299 2 p.
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92 Untranslated regions of brain-derived neurotrophic factor mRNA control its translatability and subcellular localization Lekk, Ingrid

299 2 p.
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93 Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry Arang, Nadia

299 2 p.
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                             93 gevonden resultaten
 
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