nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells
|
Greulich, Benjamin M. |
|
|
299 |
12 |
p. |
artikel |
2 |
A conserved core region of the scaffold NEMO is essential for signal-induced conformational change and liquid-liquid phase separation
|
DiRusso, Christopher J. |
|
|
299 |
12 |
p. |
artikel |
3 |
Adenine base editor–mediated splicing remodeling activates noncanonical splice sites
|
Liu, Yuanyuan |
|
|
299 |
12 |
p. |
artikel |
4 |
Adipocyte-derived exosomal miR-22-3p modulated by circadian rhythm disruption regulates insulin sensitivity in skeletal muscle cells
|
Zhang, Haohao |
|
|
299 |
12 |
p. |
artikel |
5 |
ADP-ribose contributions to genome stability and PARP enzyme trapping on sites of DNA damage; paradigm shifts for a coming-of-age modification
|
Rouleau-Turcotte, Élise |
|
|
299 |
12 |
p. |
artikel |
6 |
A gastrointestinal locally activating Janus kinase inhibitor to treat ulcerative colitis
|
Bu, Yingzi |
|
|
299 |
12 |
p. |
artikel |
7 |
A highly specific antibody against the core fucose of the N-glycan in IgG identifies the pulmonary diseases and its regulation by CCL2
|
Kanto, Noriko |
|
|
299 |
12 |
p. |
artikel |
8 |
AMPKα1 negatively regulates osteoclastogenesis and mitigates pathological bone loss
|
Ribeiro, Mariana S.P. |
|
|
299 |
12 |
p. |
artikel |
9 |
A novel family of sugar-specific phosphodiesterases that remove zwitterionic modifications of GlcNAc
|
Fossa, Samantha L. |
|
|
299 |
12 |
p. |
artikel |
10 |
An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses
|
Cheng, Norton |
|
|
299 |
12 |
p. |
artikel |
11 |
Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation
|
Aggarwal, Geetika |
|
|
299 |
12 |
p. |
artikel |
12 |
β-arrestin1 is an E3 ubiquitin ligase adaptor for substrate linear polyubiquitination
|
McElrath, Chandler J. |
|
|
299 |
12 |
p. |
artikel |
13 |
Assembly of SARS-CoV-2 ribonucleosomes by truncated N∗ variant of the nucleocapsid protein
|
Adly, Armin N. |
|
|
299 |
12 |
p. |
artikel |
14 |
Association of DDX5/p68 protein with the upstream erythroid enhancer element (EHS1) of the gene encoding the KLF1 transcription factor
|
Chen, Xiaoyong |
|
|
299 |
12 |
p. |
artikel |
15 |
Atypical genotoxicity of carcinogenic nickel(II): Linkage to dNTP biosynthesis, DNA-incorporated rNMPs, and impaired repair of TOP1-DNA crosslinks
|
Krawic, Casey |
|
|
299 |
12 |
p. |
artikel |
16 |
Barley Nodulin 26-like intrinsic protein permeates water, metalloids, saccharides, and ion pairs due to structural plasticity and diversification
|
Venkataraghavan, Akshayaa |
|
|
299 |
12 |
p. |
artikel |
17 |
Beta-cell compensation and gestational diabetes
|
Usman, Taofeek O. |
|
|
299 |
12 |
p. |
artikel |
18 |
Binding of perilipin 3 to membranes containing diacylglycerol is mediated by conserved residues within its PAT domain
|
Stribny, Jiri |
|
|
299 |
12 |
p. |
artikel |
19 |
“Boundary residues” between the folded RNA recognition motif and disordered RGG domains are critical for FUS–RNA binding
|
Balasubramanian, Sangeetha |
|
|
299 |
12 |
p. |
artikel |
20 |
cAMP competitively inhibits periplasmic phosphatases to coordinate nutritional growth with competence of Haemophilus influenzae
|
Kronborg, Kristina |
|
|
299 |
12 |
p. |
artikel |
21 |
Cardioprotective O-GlcNAc signaling is elevated in murine female hearts via enhanced O-GlcNAc transferase activity
|
Narayanan, Bhargavi |
|
|
299 |
12 |
p. |
artikel |
22 |
CBAP regulates the function of Akt-associated TSC protein complexes to modulate mTORC1 signaling
|
Liao, Wei-Ting |
|
|
299 |
12 |
p. |
artikel |
23 |
Cell aggregation activates small GTPase Rac1 and induces CD44 cleavage by maintaining lipid raft integrity
|
Li, Dong |
|
|
299 |
12 |
p. |
artikel |
24 |
Characterization of erythroferrone structural domains relevant to its iron-regulatory function
|
Srole, Daniel N. |
|
|
299 |
12 |
p. |
artikel |
25 |
Chikungunya virus nonstructural protein 1 is a versatile RNA capping and decapping enzyme
|
Law, Michelle Cheok Yien |
|
|
299 |
12 |
p. |
artikel |
26 |
Collagen IV of basement membranes: II. Emergence of collagen IVα345 enabled the assembly of a compact GBM as an ultrafilter in mammalian kidneys
|
Pokidysheva, Elena N. |
|
|
299 |
12 |
p. |
artikel |
27 |
Collagen IV of basement membranes: IV. Adaptive mechanism of collagen IV scaffold assembly in Drosophila
|
Summers, Jacob A. |
|
|
299 |
12 |
p. |
artikel |
28 |
Contribution of the yeast bi-chaperone system in the restoration of the RNA helicase Ded1 and translational activity under severe ethanol stress
|
Ando, Ryoko |
|
|
299 |
12 |
p. |
artikel |
29 |
Correction: GC × GC-TOFMS metabolomics analysis identifies elevated levels of plasma sugars and sugar alcohols in diabetic mellitus patients with kidney failure
|
Duangkumpha, Kassaporn |
|
|
299 |
12 |
p. |
artikel |
30 |
Cover
|
|
|
|
299 |
12 |
p. |
artikel |
31 |
Cryo-EM structures of RNA polymerase II–nucleosome complexes rewrapping transcribed DNA
|
Akatsu, Munetaka |
|
|
299 |
12 |
p. |
artikel |
32 |
c-Src regulates δ-secretase activation and truncated Tau production by phosphorylating the E3 ligase Traf6
|
Jiang, Yanli |
|
|
299 |
12 |
p. |
artikel |
33 |
Cyclase-associated protein interacts with actin filament barbed ends to promote depolymerization and formin displacement
|
Alimov, Nikita |
|
|
299 |
12 |
p. |
artikel |
34 |
Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes
|
Wu, Heng |
|
|
299 |
12 |
p. |
artikel |
35 |
Deciphering specificity and cross-reactivity in tachykinin NK1 and NK2 receptors
|
Madsen, Jesper J. |
|
|
299 |
12 |
p. |
artikel |
36 |
Deletion of prolyl hydroxylase domain-containing enzyme 3 (phd3) in zebrafish facilitates hypoxia tolerance
|
Liao, Qian |
|
|
299 |
12 |
p. |
artikel |
37 |
Developing multispecies quorum-sensing modulators based on the Streptococcus mitis competence-stimulating peptide
|
Milly, Tahmina A. |
|
|
299 |
12 |
p. |
artikel |
38 |
Discovery of an unusual copper homeostatic mechanism in yeast cells respiring on minimal medium and an unexpectedly diverse labile copper pool
|
Kim, Joshua E. |
|
|
299 |
12 |
p. |
artikel |
39 |
Discovery of FERM domain protein–protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer’s disease
|
Du, Yuhong |
|
|
299 |
12 |
p. |
artikel |
40 |
Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation
|
Roman, Joseph V. |
|
|
299 |
12 |
p. |
artikel |
41 |
Diverse gut pathogens exploit the host engulfment pathway via a conserved mechanism
|
Anandachar, Mahitha Shree |
|
|
299 |
12 |
p. |
artikel |
42 |
DNA conformational dynamics in the context-dependent non-CG CHH methylation by plant methyltransferase DRM2
|
Chen, Jianbin |
|
|
299 |
12 |
p. |
artikel |
43 |
Drug discovery for heart failure targeting myosin-binding protein C
|
Bunch, Thomas A. |
|
|
299 |
12 |
p. |
artikel |
44 |
Enhanced Akt3 kinase activity reduces atherosclerosis in hyperlipidemic mice in a gender-dependent manner
|
Zhang, Lifang |
|
|
299 |
12 |
p. |
artikel |
45 |
E3 ubiquitin ligase ZBTB25 suppresses beta coronavirus infection through ubiquitination of the main viral protease MPro
|
Lear, Travis B. |
|
|
299 |
12 |
p. |
artikel |
46 |
Evaluation of potential role of R-loop and G-quadruplex DNA in the fragility of c-MYC during chromosomal translocation associated with Burkitt’s lymphoma
|
Kumari, Nitu |
|
|
299 |
12 |
p. |
artikel |
47 |
Exosomes drive ferroptosis by stimulating iron accumulation to inhibit bacterial infection in crustaceans
|
Sun, Qian |
|
|
299 |
12 |
p. |
artikel |
48 |
Fanconi anemia-associated mutation in RAD51 compromises the coordinated action of DNA-binding and ATPase activities
|
Liu, Sijia |
|
|
299 |
12 |
p. |
artikel |
49 |
FOSL1 modulates Schwann cell responses in the wound microenvironment and regulates peripheral nerve regeneration
|
Chen, Qianqian |
|
|
299 |
12 |
p. |
artikel |
50 |
Functional characterization of the CRY2 circadian clock component variant p.Ser420Phe revealed a new degradation pathway for CRY2
|
Parlak, Gizem Cagla |
|
|
299 |
12 |
p. |
artikel |
51 |
Gene purging and the evolution of Neoave metabolism and longevity
|
Ng, Deanna |
|
|
299 |
12 |
p. |
artikel |
52 |
HilE represses the activity of the Salmonella virulence regulator HilD via a mechanism distinct from that of intestinal long-chain fatty acids
|
Joiner, Joe D. |
|
|
299 |
12 |
p. |
artikel |
53 |
Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission
|
Nolden, Kelsey A. |
|
|
299 |
12 |
p. |
artikel |
54 |
Human V-ATPase a-subunit isoforms bind specifically to distinct phosphoinositide phospholipids
|
Mitra, Connie |
|
|
299 |
12 |
p. |
artikel |
55 |
Hydrophobic interaction between the TM1 and H8 is essential for rhodopsin trafficking to vertebrate photoreceptor outer segments
|
Verma, Dipesh Kumar |
|
|
299 |
12 |
p. |
artikel |
56 |
Identification of novel plant cysteine oxidase inhibitors from a yeast chemical genetic screen
|
Lavilla-Puerta, Mikel |
|
|
299 |
12 |
p. |
artikel |
57 |
Identification of the functional PD-L1 interface region responsible for PD-1 binding and initiation of PD-1 signaling
|
Carter, Rachel |
|
|
299 |
12 |
p. |
artikel |
58 |
Interaction between the mitochondrial adaptor MIRO and the motor adaptor TRAK
|
Baltrusaitis, Elana E. |
|
|
299 |
12 |
p. |
artikel |
59 |
In vivo evidence for GDP-fucose transport in the absence of transporter SLC35C1 and putative transporter SLC35C2
|
Lu, Linchao |
|
|
299 |
12 |
p. |
artikel |
60 |
Iron homeostasis proteins Grx4 and Fra2 control activity of the Schizosaccharomyces pombe iron repressor Fep1 by facilitating [2Fe-2S] cluster removal
|
Hati, Debolina |
|
|
299 |
12 |
p. |
artikel |
61 |
Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma
|
Baqai, Usman |
|
|
299 |
12 |
p. |
artikel |
62 |
Leishmania PNUTS discriminates between PP1 catalytic subunits through an RVxF–ΦΦ–F motif and polymorphisms in the PP1 C-tail and catalytic domain
|
Zhang, Yang |
|
|
299 |
12 |
p. |
artikel |
63 |
Lipid environment modulates processivity and kinetics of a presenilin homolog acting on multiple substrates in vitro
|
Wu, Yuqi |
|
|
299 |
12 |
p. |
artikel |
64 |
Loss of muscle PDH induces lactic acidosis and adaptive anaplerotic compensation via pyruvate-alanine cycling and glutaminolysis
|
Gopal, Keshav |
|
|
299 |
12 |
p. |
artikel |
65 |
Macromolecular crowding potently stimulates DNA supercoiling activity of Mycobacterium tuberculosis DNA gyrase
|
Deng, Zifang |
|
|
299 |
12 |
p. |
artikel |
66 |
Mapping immunological and host receptor binding determinants of SARS-CoV spike protein utilizing the Qubevirus platform
|
Sanders, Carrie |
|
|
299 |
12 |
p. |
artikel |
67 |
Metformin inhibits digestive proteases and impairs protein digestion in mice
|
Kelly, Caleb J. |
|
|
299 |
12 |
p. |
artikel |
68 |
miR-125a-5p/miR-125b-5p contributes to pathological activation of angiotensin II-AT1R in mouse distal convoluted tubule cells by the suppression of Atrap
|
Hirota, Keigo |
|
|
299 |
12 |
p. |
artikel |
69 |
Mitochondrial hydrogen peroxide production by pyruvate dehydrogenase and α-ketoglutarate dehydrogenase in oxidative eustress and oxidative distress
|
Chalifoux, Olivia |
|
|
299 |
12 |
p. |
artikel |
70 |
Mitochondrial permeability transition regulator, cyclophilin D, is transcriptionally activated by C/EBP during adipogenesis
|
Yu, Chen |
|
|
299 |
12 |
p. |
artikel |
71 |
Molecular mechanism of EAG1 channel inhibition by imipramine binding to the PAS domain
|
Wang, Ze-Jun |
|
|
299 |
12 |
p. |
artikel |
72 |
More is different: Reconstituting complexity in microtubule regulation
|
Lawrence, Elizabeth J. |
|
|
299 |
12 |
p. |
artikel |
73 |
mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome
|
Low, Jason K.K. |
|
|
299 |
12 |
p. |
artikel |
74 |
Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms
|
Benner, Orion |
|
|
299 |
12 |
p. |
artikel |
75 |
Multistep conformational changes leading to the gate opening of light-driven sodium pump rhodopsin
|
Sato, Yukino |
|
|
299 |
12 |
p. |
artikel |
76 |
Neuron-specific gene NSG1 binds to and positively regulates sortilin ectodomain shedding via a metalloproteinase-dependent mechanism
|
Overby, Malene |
|
|
299 |
12 |
p. |
artikel |
77 |
NOTCH2 sensitizes the chondrocyte to the inflammatory response of tumor necrosis factor α
|
Canalis, Ernesto |
|
|
299 |
12 |
p. |
artikel |
78 |
Palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling activity and minor effects on cardiac hypertrophy
|
Baldwin, Tanya A. |
|
|
299 |
12 |
p. |
artikel |
79 |
Peptides designed from a bacteriophage capsid protein function as synthetic transcription repressors
|
Sharma, Pankaj V. |
|
|
299 |
12 |
p. |
artikel |
80 |
Phosphate uptake restriction, phosphate export, and polyphosphate synthesis contribute synergistically to cellular proliferation and survival
|
Takado, Masahiro |
|
|
299 |
12 |
p. |
artikel |
81 |
Posttranslational modification and heme cavity architecture of human eosinophil peroxidase—insights from first crystal structure and biochemical characterization
|
Pfanzagl, Vera |
|
|
299 |
12 |
p. |
artikel |
82 |
Prioritizing cardiovascular disease-associated variants altering NKX2-5 and TBX5 binding through an integrative computational approach
|
Peña-Martínez, Edwin G. |
|
|
299 |
12 |
p. |
artikel |
83 |
Progesterone receptor membrane component 1 facilitates Ca2+ signal amplification between endosomes and the endoplasmic reticulum
|
Gunaratne, Gihan S. |
|
|
299 |
12 |
p. |
artikel |
84 |
Proteases influence colony aggregation behavior in Vibrio cholerae
|
Detomasi, Tyler C. |
|
|
299 |
12 |
p. |
artikel |
85 |
Protein arginine N-methyltransferase 2 plays a noncatalytic role in the histone methylation activity of PRMT1
|
Rowley, Michael J. |
|
|
299 |
12 |
p. |
artikel |
86 |
Rapid-reaction kinetics of the bifurcating NAD+-dependent NADPH:ferredoxin oxidoreductase NfnI from Pyrococcus furiosus
|
Ortiz, Steve |
|
|
299 |
12 |
p. |
artikel |
87 |
RecN spatially and temporally controls RecA-mediated repair of DNA double-strand breaks
|
Noda, Shunsuke |
|
|
299 |
12 |
p. |
artikel |
88 |
Redirecting the specificity of tripartite motif containing-21 scaffolds using a novel discovery and design approach
|
VanDyke, Derek |
|
|
299 |
12 |
p. |
artikel |
89 |
Reduction of oligomer size modulates the competition between cluster formation and phase separation of the tumor suppressor SPOP
|
Sabri, Nafiseh |
|
|
299 |
12 |
p. |
artikel |
90 |
Regulatory mechanisms of one-carbon metabolism enzymes
|
Petrova, Boryana |
|
|
299 |
12 |
p. |
artikel |
91 |
Resolving binding pathways and solvation thermodynamics of plant hormone receptors
|
Zhao, Chuankai |
|
|
299 |
12 |
p. |
artikel |
92 |
SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum
|
Yang, Mei |
|
|
299 |
12 |
p. |
artikel |
93 |
Singlet oxygen induces cell wall thickening and stomatal density reducing by transcriptome reprogramming
|
Zhang, Zhong-Wei |
|
|
299 |
12 |
p. |
artikel |
94 |
SLC3A2 N-glycosylation and Golgi remodeling regulate SLC7A amino acid exchangers and stress mitigation
|
Zhang, Cunjie |
|
|
299 |
12 |
p. |
artikel |
95 |
Smurf1 polyubiquitinates on K285/K282 of the kinases Mst1/2 to attenuate their tumor-suppressor functions
|
Xu, Yana |
|
|
299 |
12 |
p. |
artikel |
96 |
Spleen Tyrosine Kinase phosphorylates VE-cadherin to cause endothelial barrier disruption in acute lung injury
|
Shadab, Mohammad |
|
|
299 |
12 |
p. |
artikel |
97 |
Steady-state regulation of COPII-dependent secretory cargo sorting by inositol trisphosphate receptors, calcium, and penta EF hand proteins
|
Held, Aaron |
|
|
299 |
12 |
p. |
artikel |
98 |
Sterol-activated amyloid beta fibril formation
|
Cook, Ian |
|
|
299 |
12 |
p. |
artikel |
99 |
Structural and functional studies reveal the molecular basis of substrate promiscuity of a glycosyltransferase originating from a major agricultural pest
|
Arriaza, Ricardo Hernandez |
|
|
299 |
12 |
p. |
artikel |
100 |
Structure of phosphorylated-like RssB, the adaptor delivering σs to the ClpXP proteolytic machinery, reveals an interface switch for activation
|
Brugger, Christiane |
|
|
299 |
12 |
p. |
artikel |
101 |
Systematic evaluation of multiple NGS platforms for structural variants detection
|
Meng, Xuan |
|
|
299 |
12 |
p. |
artikel |
102 |
TBK1-stabilized ZNF268a recruits SETD4 to methylate TBK1 for efficient interferon signaling
|
Liu, Yi |
|
|
299 |
12 |
p. |
artikel |
103 |
The adaptor protein 14-3-3zeta modulates intestinal immunity and aging in Drosophila
|
Fan, Xiaolan |
|
|
299 |
12 |
p. |
artikel |
104 |
The Arabidopsis SWEET1 and SWEET2 uniporters recognize similar substrates while differing in subcellular localization
|
Gwon, Sojeong |
|
|
299 |
12 |
p. |
artikel |
105 |
The dimerized pentraxin-like domain of the adhesion G protein–coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces
|
Kieslich, Björn |
|
|
299 |
12 |
p. |
artikel |
106 |
The heparin-binding hemagglutinin protein of Mycobacterium tuberculosis is a nucleoid-associated protein
|
Keshavam, Chetkar Chandra |
|
|
299 |
12 |
p. |
artikel |
107 |
The Legionella autoinducer LAI-1 is delivered by outer membrane vesicles to promote interbacterial and interkingdom signaling
|
Fan, Mingzhen |
|
|
299 |
12 |
p. |
artikel |
108 |
The leucine zipper domain of the transcriptional repressor Opi1 underlies a signal transduction mechanism regulating lipid synthesis
|
Fernández-Murray, J. Pedro |
|
|
299 |
12 |
p. |
artikel |
109 |
The molecular basis of dapsone activation of CYP2C9-catalyzed nonsteroidal anti-inflammatory drug oxidation
|
Nair, Pramod C. |
|
|
299 |
12 |
p. |
artikel |
110 |
The Rax homeoprotein in Müller glial cells is required for homeostasis maintenance of the postnatal mouse retina
|
Yoshimoto, Takuya |
|
|
299 |
12 |
p. |
artikel |
111 |
The toxicities of A30P and A53T α-synuclein fibrils can be uniquely altered by the length and saturation of fatty acids in phosphatidylserine
|
Ali, Abid |
|
|
299 |
12 |
p. |
artikel |
112 |
The underlying mechanical properties of membranes tune their ability to fuse
|
Lira, Rafael B. |
|
|
299 |
12 |
p. |
artikel |
113 |
The universe of galectin-binding partners and their functions in health and disease
|
Troncoso, María F. |
|
|
299 |
12 |
p. |
artikel |
114 |
The YmgB-SpoT interaction triggers the stringent response in Escherichia coli
|
Guiraud, Paul |
|
|
299 |
12 |
p. |
artikel |
115 |
tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10
|
Strassler, Sarah E. |
|
|
299 |
12 |
p. |
artikel |
116 |
TTC17 is an endoplasmic reticulum resident TPR-containing adaptor protein
|
Canniff, Nathan P. |
|
|
299 |
12 |
p. |
artikel |
117 |
Understanding and exploiting the roles of O-GlcNAc in neurodegenerative diseases
|
Pratt, Matthew R. |
|
|
299 |
12 |
p. |
artikel |
118 |
Unifying and versatile features of flavin-dependent monooxygenases: Diverse catalysis by a common C4a-(hydro)peroxyflavin
|
Phintha, Aisaraphon |
|
|
299 |
12 |
p. |
artikel |
119 |
Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization
|
Ilmain, Juliana K. |
|
|
299 |
12 |
p. |
artikel |
120 |
Using CRISPR-Cas9/phosphoproteomics to identify substrates of calcium/calmodulin-dependent kinase 2δ
|
Park, Euijung |
|
|
299 |
12 |
p. |
artikel |
121 |
Withdrawal: Sulforaphane attenuates muscle inflammation in dystrophin-deficient mdx mice via NF-E2-related factor 2 (Nrf2)-mediated inhibition of NF-κB signaling pathway
|
Sun, Cheng-Cao |
|
|
299 |
12 |
p. |
artikel |