Digitale Bibliotheek
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                             121 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells Greulich, Benjamin M.

299 12 p.
artikel
2 A conserved core region of the scaffold NEMO is essential for signal-induced conformational change and liquid-liquid phase separation DiRusso, Christopher J.

299 12 p.
artikel
3 Adenine base editor–mediated splicing remodeling activates noncanonical splice sites Liu, Yuanyuan

299 12 p.
artikel
4 Adipocyte-derived exosomal miR-22-3p modulated by circadian rhythm disruption regulates insulin sensitivity in skeletal muscle cells Zhang, Haohao

299 12 p.
artikel
5 ADP-ribose contributions to genome stability and PARP enzyme trapping on sites of DNA damage; paradigm shifts for a coming-of-age modification Rouleau-Turcotte, Élise

299 12 p.
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6 A gastrointestinal locally activating Janus kinase inhibitor to treat ulcerative colitis Bu, Yingzi

299 12 p.
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7 A highly specific antibody against the core fucose of the N-glycan in IgG identifies the pulmonary diseases and its regulation by CCL2 Kanto, Noriko

299 12 p.
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8 AMPKα1 negatively regulates osteoclastogenesis and mitigates pathological bone loss Ribeiro, Mariana S.P.

299 12 p.
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9 A novel family of sugar-specific phosphodiesterases that remove zwitterionic modifications of GlcNAc Fossa, Samantha L.

299 12 p.
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10 An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses Cheng, Norton

299 12 p.
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11 Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation Aggarwal, Geetika

299 12 p.
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12 β-arrestin1 is an E3 ubiquitin ligase adaptor for substrate linear polyubiquitination McElrath, Chandler J.

299 12 p.
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13 Assembly of SARS-CoV-2 ribonucleosomes by truncated N∗ variant of the nucleocapsid protein Adly, Armin N.

299 12 p.
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14 Association of DDX5/p68 protein with the upstream erythroid enhancer element (EHS1) of the gene encoding the KLF1 transcription factor Chen, Xiaoyong

299 12 p.
artikel
15 Atypical genotoxicity of carcinogenic nickel(II): Linkage to dNTP biosynthesis, DNA-incorporated rNMPs, and impaired repair of TOP1-DNA crosslinks Krawic, Casey

299 12 p.
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16 Barley Nodulin 26-like intrinsic protein permeates water, metalloids, saccharides, and ion pairs due to structural plasticity and diversification Venkataraghavan, Akshayaa

299 12 p.
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17 Beta-cell compensation and gestational diabetes Usman, Taofeek O.

299 12 p.
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18 Binding of perilipin 3 to membranes containing diacylglycerol is mediated by conserved residues within its PAT domain Stribny, Jiri

299 12 p.
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19 “Boundary residues” between the folded RNA recognition motif and disordered RGG domains are critical for FUS–RNA binding Balasubramanian, Sangeetha

299 12 p.
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20 cAMP competitively inhibits periplasmic phosphatases to coordinate nutritional growth with competence of Haemophilus influenzae Kronborg, Kristina

299 12 p.
artikel
21 Cardioprotective O-GlcNAc signaling is elevated in murine female hearts via enhanced O-GlcNAc transferase activity Narayanan, Bhargavi

299 12 p.
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22 CBAP regulates the function of Akt-associated TSC protein complexes to modulate mTORC1 signaling Liao, Wei-Ting

299 12 p.
artikel
23 Cell aggregation activates small GTPase Rac1 and induces CD44 cleavage by maintaining lipid raft integrity Li, Dong

299 12 p.
artikel
24 Characterization of erythroferrone structural domains relevant to its iron-regulatory function Srole, Daniel N.

299 12 p.
artikel
25 Chikungunya virus nonstructural protein 1 is a versatile RNA capping and decapping enzyme Law, Michelle Cheok Yien

299 12 p.
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26 Collagen IV of basement membranes: II. Emergence of collagen IVα345 enabled the assembly of a compact GBM as an ultrafilter in mammalian kidneys Pokidysheva, Elena N.

299 12 p.
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27 Collagen IV of basement membranes: IV. Adaptive mechanism of collagen IV scaffold assembly in Drosophila Summers, Jacob A.

299 12 p.
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28 Contribution of the yeast bi-chaperone system in the restoration of the RNA helicase Ded1 and translational activity under severe ethanol stress Ando, Ryoko

299 12 p.
artikel
29 Correction: GC × GC-TOFMS metabolomics analysis identifies elevated levels of plasma sugars and sugar alcohols in diabetic mellitus patients with kidney failure Duangkumpha, Kassaporn

299 12 p.
artikel
30 Cover
299 12 p.
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31 Cryo-EM structures of RNA polymerase II–nucleosome complexes rewrapping transcribed DNA Akatsu, Munetaka

299 12 p.
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32 c-Src regulates δ-secretase activation and truncated Tau production by phosphorylating the E3 ligase Traf6 Jiang, Yanli

299 12 p.
artikel
33 Cyclase-associated protein interacts with actin filament barbed ends to promote depolymerization and formin displacement Alimov, Nikita

299 12 p.
artikel
34 Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes Wu, Heng

299 12 p.
artikel
35 Deciphering specificity and cross-reactivity in tachykinin NK1 and NK2 receptors Madsen, Jesper J.

299 12 p.
artikel
36 Deletion of prolyl hydroxylase domain-containing enzyme 3 (phd3) in zebrafish facilitates hypoxia tolerance Liao, Qian

299 12 p.
artikel
37 Developing multispecies quorum-sensing modulators based on the Streptococcus mitis competence-stimulating peptide Milly, Tahmina A.

299 12 p.
artikel
38 Discovery of an unusual copper homeostatic mechanism in yeast cells respiring on minimal medium and an unexpectedly diverse labile copper pool Kim, Joshua E.

299 12 p.
artikel
39 Discovery of FERM domain protein–protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer’s disease Du, Yuhong

299 12 p.
artikel
40 Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation Roman, Joseph V.

299 12 p.
artikel
41 Diverse gut pathogens exploit the host engulfment pathway via a conserved mechanism Anandachar, Mahitha Shree

299 12 p.
artikel
42 DNA conformational dynamics in the context-dependent non-CG CHH methylation by plant methyltransferase DRM2 Chen, Jianbin

299 12 p.
artikel
43 Drug discovery for heart failure targeting myosin-binding protein C Bunch, Thomas A.

299 12 p.
artikel
44 Enhanced Akt3 kinase activity reduces atherosclerosis in hyperlipidemic mice in a gender-dependent manner Zhang, Lifang

299 12 p.
artikel
45 E3 ubiquitin ligase ZBTB25 suppresses beta coronavirus infection through ubiquitination of the main viral protease MPro Lear, Travis B.

299 12 p.
artikel
46 Evaluation of potential role of R-loop and G-quadruplex DNA in the fragility of c-MYC during chromosomal translocation associated with Burkitt’s lymphoma Kumari, Nitu

299 12 p.
artikel
47 Exosomes drive ferroptosis by stimulating iron accumulation to inhibit bacterial infection in crustaceans Sun, Qian

299 12 p.
artikel
48 Fanconi anemia-associated mutation in RAD51 compromises the coordinated action of DNA-binding and ATPase activities Liu, Sijia

299 12 p.
artikel
49 FOSL1 modulates Schwann cell responses in the wound microenvironment and regulates peripheral nerve regeneration Chen, Qianqian

299 12 p.
artikel
50 Functional characterization of the CRY2 circadian clock component variant p.Ser420Phe revealed a new degradation pathway for CRY2 Parlak, Gizem Cagla

299 12 p.
artikel
51 Gene purging and the evolution of Neoave metabolism and longevity Ng, Deanna

299 12 p.
artikel
52 HilE represses the activity of the Salmonella virulence regulator HilD via a mechanism distinct from that of intestinal long-chain fatty acids Joiner, Joe D.

299 12 p.
artikel
53 Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission Nolden, Kelsey A.

299 12 p.
artikel
54 Human V-ATPase a-subunit isoforms bind specifically to distinct phosphoinositide phospholipids Mitra, Connie

299 12 p.
artikel
55 Hydrophobic interaction between the TM1 and H8 is essential for rhodopsin trafficking to vertebrate photoreceptor outer segments Verma, Dipesh Kumar

299 12 p.
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56 Identification of novel plant cysteine oxidase inhibitors from a yeast chemical genetic screen Lavilla-Puerta, Mikel

299 12 p.
artikel
57 Identification of the functional PD-L1 interface region responsible for PD-1 binding and initiation of PD-1 signaling Carter, Rachel

299 12 p.
artikel
58 Interaction between the mitochondrial adaptor MIRO and the motor adaptor TRAK Baltrusaitis, Elana E.

299 12 p.
artikel
59 In vivo evidence for GDP-fucose transport in the absence of transporter SLC35C1 and putative transporter SLC35C2 Lu, Linchao

299 12 p.
artikel
60 Iron homeostasis proteins Grx4 and Fra2 control activity of the Schizosaccharomyces pombe iron repressor Fep1 by facilitating [2Fe-2S] cluster removal Hati, Debolina

299 12 p.
artikel
61 Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma Baqai, Usman

299 12 p.
artikel
62 Leishmania PNUTS discriminates between PP1 catalytic subunits through an RVxF–ΦΦ–F motif and polymorphisms in the PP1 C-tail and catalytic domain Zhang, Yang

299 12 p.
artikel
63 Lipid environment modulates processivity and kinetics of a presenilin homolog acting on multiple substrates in vitro Wu, Yuqi

299 12 p.
artikel
64 Loss of muscle PDH induces lactic acidosis and adaptive anaplerotic compensation via pyruvate-alanine cycling and glutaminolysis Gopal, Keshav

299 12 p.
artikel
65 Macromolecular crowding potently stimulates DNA supercoiling activity of Mycobacterium tuberculosis DNA gyrase Deng, Zifang

299 12 p.
artikel
66 Mapping immunological and host receptor binding determinants of SARS-CoV spike protein utilizing the Qubevirus platform Sanders, Carrie

299 12 p.
artikel
67 Metformin inhibits digestive proteases and impairs protein digestion in mice Kelly, Caleb J.

299 12 p.
artikel
68 miR-125a-5p/miR-125b-5p contributes to pathological activation of angiotensin II-AT1R in mouse distal convoluted tubule cells by the suppression of Atrap Hirota, Keigo

299 12 p.
artikel
69 Mitochondrial hydrogen peroxide production by pyruvate dehydrogenase and α-ketoglutarate dehydrogenase in oxidative eustress and oxidative distress Chalifoux, Olivia

299 12 p.
artikel
70 Mitochondrial permeability transition regulator, cyclophilin D, is transcriptionally activated by C/EBP during adipogenesis Yu, Chen

299 12 p.
artikel
71 Molecular mechanism of EAG1 channel inhibition by imipramine binding to the PAS domain Wang, Ze-Jun

299 12 p.
artikel
72 More is different: Reconstituting complexity in microtubule regulation Lawrence, Elizabeth J.

299 12 p.
artikel
73 mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome Low, Jason K.K.

299 12 p.
artikel
74 Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms Benner, Orion

299 12 p.
artikel
75 Multistep conformational changes leading to the gate opening of light-driven sodium pump rhodopsin Sato, Yukino

299 12 p.
artikel
76 Neuron-specific gene NSG1 binds to and positively regulates sortilin ectodomain shedding via a metalloproteinase-dependent mechanism Overby, Malene

299 12 p.
artikel
77 NOTCH2 sensitizes the chondrocyte to the inflammatory response of tumor necrosis factor α Canalis, Ernesto

299 12 p.
artikel
78 Palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling activity and minor effects on cardiac hypertrophy Baldwin, Tanya A.

299 12 p.
artikel
79 Peptides designed from a bacteriophage capsid protein function as synthetic transcription repressors Sharma, Pankaj V.

299 12 p.
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80 Phosphate uptake restriction, phosphate export, and polyphosphate synthesis contribute synergistically to cellular proliferation and survival Takado, Masahiro

299 12 p.
artikel
81 Posttranslational modification and heme cavity architecture of human eosinophil peroxidase—insights from first crystal structure and biochemical characterization Pfanzagl, Vera

299 12 p.
artikel
82 Prioritizing cardiovascular disease-associated variants altering NKX2-5 and TBX5 binding through an integrative computational approach Peña-Martínez, Edwin G.

299 12 p.
artikel
83 Progesterone receptor membrane component 1 facilitates Ca2+ signal amplification between endosomes and the endoplasmic reticulum Gunaratne, Gihan S.

299 12 p.
artikel
84 Proteases influence colony aggregation behavior in Vibrio cholerae Detomasi, Tyler C.

299 12 p.
artikel
85 Protein arginine N-methyltransferase 2 plays a noncatalytic role in the histone methylation activity of PRMT1 Rowley, Michael J.

299 12 p.
artikel
86 Rapid-reaction kinetics of the bifurcating NAD+-dependent NADPH:ferredoxin oxidoreductase NfnI from Pyrococcus furiosus Ortiz, Steve

299 12 p.
artikel
87 RecN spatially and temporally controls RecA-mediated repair of DNA double-strand breaks Noda, Shunsuke

299 12 p.
artikel
88 Redirecting the specificity of tripartite motif containing-21 scaffolds using a novel discovery and design approach VanDyke, Derek

299 12 p.
artikel
89 Reduction of oligomer size modulates the competition between cluster formation and phase separation of the tumor suppressor SPOP Sabri, Nafiseh

299 12 p.
artikel
90 Regulatory mechanisms of one-carbon metabolism enzymes Petrova, Boryana

299 12 p.
artikel
91 Resolving binding pathways and solvation thermodynamics of plant hormone receptors Zhao, Chuankai

299 12 p.
artikel
92 SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum Yang, Mei

299 12 p.
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93 Singlet oxygen induces cell wall thickening and stomatal density reducing by transcriptome reprogramming Zhang, Zhong-Wei

299 12 p.
artikel
94 SLC3A2 N-glycosylation and Golgi remodeling regulate SLC7A amino acid exchangers and stress mitigation Zhang, Cunjie

299 12 p.
artikel
95 Smurf1 polyubiquitinates on K285/K282 of the kinases Mst1/2 to attenuate their tumor-suppressor functions Xu, Yana

299 12 p.
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96 Spleen Tyrosine Kinase phosphorylates VE-cadherin to cause endothelial barrier disruption in acute lung injury Shadab, Mohammad

299 12 p.
artikel
97 Steady-state regulation of COPII-dependent secretory cargo sorting by inositol trisphosphate receptors, calcium, and penta EF hand proteins Held, Aaron

299 12 p.
artikel
98 Sterol-activated amyloid beta fibril formation Cook, Ian

299 12 p.
artikel
99 Structural and functional studies reveal the molecular basis of substrate promiscuity of a glycosyltransferase originating from a major agricultural pest Arriaza, Ricardo Hernandez

299 12 p.
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100 Structure of phosphorylated-like RssB, the adaptor delivering σs to the ClpXP proteolytic machinery, reveals an interface switch for activation Brugger, Christiane

299 12 p.
artikel
101 Systematic evaluation of multiple NGS platforms for structural variants detection Meng, Xuan

299 12 p.
artikel
102 TBK1-stabilized ZNF268a recruits SETD4 to methylate TBK1 for efficient interferon signaling Liu, Yi

299 12 p.
artikel
103 The adaptor protein 14-3-3zeta modulates intestinal immunity and aging in Drosophila Fan, Xiaolan

299 12 p.
artikel
104 The Arabidopsis SWEET1 and SWEET2 uniporters recognize similar substrates while differing in subcellular localization Gwon, Sojeong

299 12 p.
artikel
105 The dimerized pentraxin-like domain of the adhesion G protein–coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces Kieslich, Björn

299 12 p.
artikel
106 The heparin-binding hemagglutinin protein of Mycobacterium tuberculosis is a nucleoid-associated protein Keshavam, Chetkar Chandra

299 12 p.
artikel
107 The Legionella autoinducer LAI-1 is delivered by outer membrane vesicles to promote interbacterial and interkingdom signaling Fan, Mingzhen

299 12 p.
artikel
108 The leucine zipper domain of the transcriptional repressor Opi1 underlies a signal transduction mechanism regulating lipid synthesis Fernández-Murray, J. Pedro

299 12 p.
artikel
109 The molecular basis of dapsone activation of CYP2C9-catalyzed nonsteroidal anti-inflammatory drug oxidation Nair, Pramod C.

299 12 p.
artikel
110 The Rax homeoprotein in Müller glial cells is required for homeostasis maintenance of the postnatal mouse retina Yoshimoto, Takuya

299 12 p.
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111 The toxicities of A30P and A53T α-synuclein fibrils can be uniquely altered by the length and saturation of fatty acids in phosphatidylserine Ali, Abid

299 12 p.
artikel
112 The underlying mechanical properties of membranes tune their ability to fuse Lira, Rafael B.

299 12 p.
artikel
113 The universe of galectin-binding partners and their functions in health and disease Troncoso, María F.

299 12 p.
artikel
114 The YmgB-SpoT interaction triggers the stringent response in Escherichia coli Guiraud, Paul

299 12 p.
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115 tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10 Strassler, Sarah E.

299 12 p.
artikel
116 TTC17 is an endoplasmic reticulum resident TPR-containing adaptor protein Canniff, Nathan P.

299 12 p.
artikel
117 Understanding and exploiting the roles of O-GlcNAc in neurodegenerative diseases Pratt, Matthew R.

299 12 p.
artikel
118 Unifying and versatile features of flavin-dependent monooxygenases: Diverse catalysis by a common C4a-(hydro)peroxyflavin Phintha, Aisaraphon

299 12 p.
artikel
119 Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization Ilmain, Juliana K.

299 12 p.
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120 Using CRISPR-Cas9/phosphoproteomics to identify substrates of calcium/calmodulin-dependent kinase 2δ Park, Euijung

299 12 p.
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121 Withdrawal: Sulforaphane attenuates muscle inflammation in dystrophin-deficient mdx mice via NF-E2-related factor 2 (Nrf2)-mediated inhibition of NF-κB signaling pathway Sun, Cheng-Cao

299 12 p.
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                             121 gevonden resultaten
 
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