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                             96 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A conserved, noncanonical insert in FIS1 mediates TBC1D15 and DRP1 recruitment for mitochondrial fission Ihenacho, Ugochukwu K.

299 11 p.
artikel
2 “Affimer” synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation Roper, Barnaby W.R.

299 11 p.
artikel
3 A multiple-oscillator mechanism underlies antigen-induced Ca2+ oscillations in Jurkat T-cells Benson, J. Cory

299 11 p.
artikel
4 An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing Pan, Haihui

299 11 p.
artikel
5 Anti-tau antibodies targeting a conformation-dependent epitope selectively bind seeds Hitt, Brian D.

299 11 p.
artikel
6 A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels Icso, Janneke Doedée

299 11 p.
artikel
7 A PrP EGFR signaling axis controls neural stem cell senescence through modulating cellular energy pathways Groveman, Bradley R.

299 11 p.
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8 A real-time analysis of protein transport via the twin arginine translocation pathway in response to different components of the protonmotive force Zhou, Wenjie

299 11 p.
artikel
9 Arg177 and Asp159 from dog prion protein slow liquid–liquid phase separation and inhibit amyloid formation of human prion protein Li, Xiang-Ning

299 11 p.
artikel
10 Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients Sahlström, Peter

299 11 p.
artikel
11 Babesia BdFE1 esterase is required for the anti-parasitic activity of the ACE inhibitor fosinopril Vydyam, Pratap

299 11 p.
artikel
12 Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P Wilhelm, Catherine A.

299 11 p.
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13 BATF2 inhibits PD-L1 expression and regulates CD8+ T-cell infiltration in non–small cell lung cancer Liu, Junwei

299 11 p.
artikel
14 Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding Grädler, Ulrich

299 11 p.
artikel
15 Biophysical characterization of chloride intracellular channel 6 (CLIC6) Loyo-Celis, Veronica

299 11 p.
artikel
16 Bispecific soluble cytokine receptor-nanobody fusions inhibit Interleukin (IL-)6 trans-signaling and IL-12/23 or tumor necrosis factor (TNF) signaling Gesiorowski, Annika

299 11 p.
artikel
17 CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions Tennakoon, Mithila

299 11 p.
artikel
18 Co-folding and RNA activation of poliovirus 3Cpro polyprotein precursors Campagnola, Grace

299 11 p.
artikel
19 Collagen IV of basement membranes: III. Chloride pressure is a primordial innovation that drives and maintains the assembly of scaffolds Boudko, Sergei P.

299 11 p.
artikel
20 Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7 Harrison, Simone A.

299 11 p.
artikel
21 Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis Kiss, Robert S.

299 11 p.
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22 Cover
299 11 p.
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23 Crosstalk between the tRNA methyltransferase Trm1 and RNA chaperone La influences eukaryotic tRNA maturation Porat, Jennifer

299 11 p.
artikel
24 Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons Shimada, Atsuhiro

299 11 p.
artikel
25 Defining the molecular architecture, metal dependence, and distribution of metal-dependent class II sulfofructose-1-phosphate aldolases Sharma, Mahima

299 11 p.
artikel
26 Depletion of IQ motif-containing GTPase activating protein 2 (IQGAP2) reduces hepatic glycogen and impairs insulin signaling Sen, Anushna

299 11 p.
artikel
27 Deubiquitinase UCHL1 regulates estradiol synthesis by stabilizing voltage-dependent anion channel 2 Shi, Shengjie

299 11 p.
artikel
28 Disrupting actin filaments enhances glucose-stimulated insulin secretion independent of the cortical actin cytoskeleton Polino, Alexander J.

299 11 p.
artikel
29 Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity Theophall, Gregory G.

299 11 p.
artikel
30 Diversity in connexin biology Lucaciu, Sergiu A.

299 11 p.
artikel
31 Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43 Tanaka, Yoshinori

299 11 p.
artikel
32 4EBP2-regulated protein translation has a critical role in high-fat diet–induced insulin resistance in hepatocytes Han, Xiao

299 11 p.
artikel
33 Elongation rate of RNA polymerase II affects pausing patterns across 3′ UTRs Khitun, Alexandra

299 11 p.
artikel
34 Growing and dividing: how O-GlcNAcylation leads the way Saunders, Harmony

299 11 p.
artikel
35 Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor Burghi, Valeria

299 11 p.
artikel
36 HDGF stimulates liver tumorigenesis by enhancing reactive oxygen species generation in mitochondria Hu, Tsung-Hui

299 11 p.
artikel
37 Helicases in R-loop Formation and Resolution Yang, Shizhuo

299 11 p.
artikel
38 Hepatocyte-specific Wtap deficiency promotes hepatocellular carcinoma by activating GRB2–ERK depending on downregulation of proteasome-related genes Li, Xinzhi

299 11 p.
artikel
39 High-speed AFM imaging reveals DNA capture and loop extrusion dynamics by cohesin-NIPBL Kaur, Parminder

299 11 p.
artikel
40 HPIP and RUFY3 are noncanonical guanine nucleotide exchange factors of Rab5 to regulate endocytosis-coupled focal adhesion turnover Khumukcham, Saratchandra Singh

299 11 p.
artikel
41 Hybrid insulin peptide isomers spontaneously form in pancreatic beta-cells from an aspartic anhydride intermediate Crawford, Samantha A.

299 11 p.
artikel
42 Hydrophobic moment drives penetration of bacterial membranes by transmembrane peptides Johnson, Tyler S.

299 11 p.
artikel
43 Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription Downes, Nicholas

299 11 p.
artikel
44 IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies Frick, Inga-Maria

299 11 p.
artikel
45 Insulin-like growth factor binding protein-3 mediates hyperosmolar stress–induced mitophagy through the mechanistic target of rapamycin Stuard Sambhariya, Whitney

299 11 p.
artikel
46 Intralumenal docking of connexin 36 channels in the ER isolates mistrafficked protein Tetenborg, Stephan

299 11 p.
artikel
47 Mechanistic characterization of disulfide bond reduction of an ERAD substrate mediated by cooperation between ERdj5 and BiP Cai, Xiaohan

299 11 p.
artikel
48 Metaorganismal choline metabolism shapes olfactory perception Massey, William J.

299 11 p.
artikel
49 Molecular mechanism for endo-type action of glycoside hydrolase family 55 endo-β-1,3-glucanase on β1-3/1-6-glucan Ota, Tomoya

299 11 p.
artikel
50 Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most Mycolicibacterium smegmatis mRNAs Zhou, Ying

299 11 p.
artikel
51 Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways van Wigcheren, Glenn F.

299 11 p.
artikel
52 O-GlcNAc has crosstalk with ADP-ribosylation via PARG Li, Jie

299 11 p.
artikel
53 On a sugar high: Role of O-GlcNAcylation in cancer Le Minh, Giang

299 11 p.
artikel
54 Outer membrane protein 25 of Brucella suppresses TLR-mediated expression of proinflammatory cytokines through degradation of TLRs and adaptor proteins Murugan, Subathra

299 11 p.
artikel
55 8-Oxoguanine DNA glycosylase 1 selectively modulates ROS-responsive NF-κB targets through recruitment of MSK1 and phosphorylation of RelA/p65 at Ser276 Xue, Yaoyao

299 11 p.
artikel
56 Phase plane dynamics of ERK phosphorylation Shvartsman, Stanislav Y.

299 11 p.
artikel
57 Phenotypic analysis with trans-recombination–based genetic mosaic models Zhang, Yu

299 11 p.
artikel
58 Proline provides a nitrogen source in the retinal pigment epithelium to synthesize and export amino acids for the neural retina Zhu, Siyan

299 11 p.
artikel
59 Protection of eIF2B from inhibitory phosphorylated eIF2: A viral strategy to maintain mRNA translation during the PKR-triggered integrated stress response Ito, Takuhiro

299 11 p.
artikel
60 Protein interaction network analysis of mTOR signaling reveals modular organization Wehle, Devin T.

299 11 p.
artikel
61 Pseudomonas aeruginosa AlgF is a protein–protein interaction mediator required for acetylation of the alginate exopolysaccharide Low, Kristin E.

299 11 p.
artikel
62 P-type ATPases: Many more enigmas left to solve Palmgren, Michael

299 11 p.
artikel
63 Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism Arp, Nicholas L.

299 11 p.
artikel
64 Respiratory syncytial virus–approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors Ettich, Julia

299 11 p.
artikel
65 Retardation of Aβ42 fibril formation by apolipoprotein A-I and recombinant HDL particles Frankel, Rebecca

299 11 p.
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66 Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease Chen, Jerry

299 11 p.
artikel
67 ROR2 homodimerization is sufficient to activate a neuronal Wnt/calcium signaling pathway Riquelme, Raul

299 11 p.
artikel
68 Selective targeting and clustering of phosphatidylserine lipids by RSV M protein is critical for virus particle production Swain, Jitendriya

299 11 p.
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69 Sequence tolerance of immunoglobulin variable domain framework regions to noncanonical intradomain disulfide linkages Kim, Dae Young

299 11 p.
artikel
70 SGCE promotes breast cancer stemness by promoting the transcription of FGF-BP1 by Sp1 Qiu, Ting

299 11 p.
artikel
71 STPP-UP: An alternative method for drug target identification using protein thermal stability Zijlmans, Dick W.

299 11 p.
artikel
72 Structural basis of aggregate binding by the AAA+ disaggregase ClpG Katikaridis, Panagiotis

299 11 p.
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73 Structural basis of membrane machines that traffick and attach heme to cytochromes Huynh, Jonathan Q.

299 11 p.
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74 Structural insights into Rad18 targeting by the SLF1 BRCT domains Huang, Wei

299 11 p.
artikel
75 Structural insights of the p97/VCP AAA+ ATPase: How adapter interactions coordinate diverse cellular functionality Braxton, Julian R.

299 11 p.
artikel
76 SUMOylation indirectly suppresses activity of the HIF-1α pathway in intestinal epithelial cells Malkov, Mykyta I.

299 11 p.
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77 The adaptability of the ion-binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF Lithgo, Ryan M.

299 11 p.
artikel
78 The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks Herrera, Luis Reza

299 11 p.
artikel
79 The capsaicin binding affinity of wildtype and mutant TRPV1 ion channels Li, Shisheng

299 11 p.
artikel
80 The C-terminal domain of the antiamyloid chaperone DNAJB6 binds to amyloid-β peptide fibrils and inhibits secondary nucleation Österlund, Nicklas

299 11 p.
artikel
81 The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase Forsberg, Zarah

299 11 p.
artikel
82 The kinesin-14 family motor protein KIFC2 promotes prostate cancer progression by regulating p65 Liu, Xinyu

299 11 p.
artikel
83 The long noncoding RNA lnc-H19 is important for endurance exercise by maintaining slow muscle fiber types Yue, Yongqi

299 11 p.
artikel
84 The microtubule quartet protein SNAP1 in Trypanosoma brucei facilitates flagellum and cell division plane positioning by promoting basal body segregation Souza Onofre, Thiago

299 11 p.
artikel
85 The microtubule-severing protein UNC-45A preferentially binds to curved microtubules and counteracts the microtubule-straightening effects of Taxol Hoshino, Asumi

299 11 p.
artikel
86 The mitochondrial amidoxime reducing component—from prodrug-activation mechanism to drug-metabolizing enzyme and onward to drug target Struwe, Michel A.

299 11 p.
artikel
87 The mutations on the envelope glycoprotein D contribute to the enhanced neurotropism of the pseudorabies virus variant Wu, Hongxia

299 11 p.
artikel
88 The nexus between reactive oxygen species and the mechanism of action of herbicides Traxler, Catherine

299 11 p.
artikel
89 The preferential transport of NO3 − by full-length Guillardia theta anion channelrhodopsin 1 is enhanced by its extended cytoplasmic domain Ohki, Yuya

299 11 p.
artikel
90 The solution structure of the heavy chain–only C5-Fc nanobody reveals exposed variable regions that are optimal for COVID-19 antigen interactions Gao, Xin

299 11 p.
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91 The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations Klontz, Erik

299 11 p.
artikel
92 Time-resolved study on signaling pathway of photoactivated adenylate cyclase and its nonlinear optical response Nakasone, Yusuke

299 11 p.
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93 Turnover and bypass of p21-activated kinase during Cdc42-dependent MAPK signaling in yeast González, Beatriz

299 11 p.
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94 Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity Maurer, Sigrun K.

299 11 p.
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95 Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development Su, Dan

299 11 p.
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96 Zymograph profiling reveals a divergent evolution of sirtuin that may originate from class III enzymes Yang, Yujiao

299 11 p.
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                             96 gevonden resultaten
 
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