Digitale Bibliotheek
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                             87 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A broad specificity β-propeller enzyme from Rhodopseudomonas palustris that hydrolyzes many lactones including γ-valerolactone Hall, Benjamin W.

299 1 p.
artikel
2 Acetyl-CoA carboxylase 1 depletion suppresses de novo fatty acid synthesis and mitochondrial β-oxidation in castration-resistant prostate cancer cells Liu, Shaoyou

299 1 p.
artikel
3 Activation of amygdala prokineticin receptor 2 neurons drives the anorexigenic activity of the neuropeptide PK2 Yin, Terry C.

299 1 p.
artikel
4 Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors Lee, Ee-Soo

299 1 p.
artikel
5 A midposition NOTCH3 truncation in inherited cerebral small vessel disease may affect the protein interactome Lee, Soo Jung

299 1 p.
artikel
6 An evolutionarily conserved N-terminal leucine is essential for MX1 GTPase antiviral activity against different families of RNA viruses McKellar, Joe

299 1 p.
artikel
7 A peptide derived from adaptor protein STAP-2 inhibits tumor progression by downregulating epidermal growth factor receptor signaling Maemoto, Taiga

299 1 p.
artikel
8 Application of mutational profiling: New functional analyses reveal the tRNA recognition mechanism of tRNA m1A22 methyltransferase Yamagami, Ryota

299 1 p.
artikel
9 Archeal tRNA meets biotechnology: From vaccines to genetic code expansion Ribas de Pouplana, Lluís

299 1 p.
artikel
10 Arginine-rich C9ORF72 ALS proteins stall ribosomes in a manner distinct from a canonical ribosome-associated quality control substrate Kriachkov, Viacheslav

299 1 p.
artikel
11 A splicing-dependent ER retention signal regulates surface expression of the mechanosensitive TMEM63B cation channel Wu, Dan

299 1 p.
artikel
12 A tumor microenvironment-activated metal-organic framework–based nanoplatform for amplified oxidative stress–induced enhanced chemotherapy Li, Bo

299 1 p.
artikel
13 Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer Acharya, Srijan

299 1 p.
artikel
14 BY-kinases: Protein tyrosine kinases like no other Hajredini, Fatlum

299 1 p.
artikel
15 Calmodulin variant E140G associated with long QT syndrome impairs CaMKIIδ autophosphorylation and L-type calcium channel inactivation Prakash, Ohm

299 1 p.
artikel
16 Characterization of the Escherichia coli XPD/Rad3 iron-sulfur helicase YoaA in complex with the DNA polymerase III clamp loader subunit chi (χ) Weeks-Pollenz, Savannah J.

299 1 p.
artikel
17 Correction: Parkin ubiquitinates TAR-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6) Hebron, Michaeline L.

299 1 p.
artikel
18 Correction: Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation Nagy, Zoltán Attila

299 1 p.
artikel
19 Correction: The Wnt target protein Peter Pan defines a novel p53-independent nucleolar stress-response pathway Pfister, Astrid S.

299 1 p.
artikel
20 Cover
299 1 p.
artikel
21 Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction Kulczyk, Arkadiusz W.

299 1 p.
artikel
22 Deep mutational analysis of elongation factor eEF2 residues implicated in human disease to identify functionally important contacts with the ribosome Olson, Alexandra N.

299 1 p.
artikel
23 Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains Hay, Iain M.

299 1 p.
artikel
24 Deubiquitinase USP2 stabilizes the MRE11–RAD50–NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1 Kim, Hyunsup

299 1 p.
artikel
25 Difluoromethyl-1,3,4-oxadiazoles are slow-binding substrate analog inhibitors of histone deacetylase 6 with unprecedented isotype selectivity Cellupica, Edoardo

299 1 p.
artikel
26 Diptoindonesin G, a new Hsp90 drug Wickramaratne, Anushka

299 1 p.
artikel
27 DNA damage to bone marrow stromal cells by antileukemia drugs induces chemoresistance in acute myeloid leukemia via paracrine FGF10–FGFR2 signaling Yu, Shuang

299 1 p.
artikel
28 DNA repair protein RAD52 is required for protecting G-quadruplexes in mammalian cells Liu, Shuo

299 1 p.
artikel
29 Exploration of the cysteine reactivity of human inducible Hsp70 and cognate Hsc70 Hong, Zhouping

299 1 p.
artikel
30 Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth Wisniewski, David J.

299 1 p.
artikel
31 Free fatty acids stabilize integrin β1 via S-nitrosylation to promote monocyte–endothelial adhesion Yao, Qinyu

299 1 p.
artikel
32 Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles Lee, Lindsey A.

299 1 p.
artikel
33 Glucose transporter GLUT1 expression is important for oriental river prawn (Macrobrachium nipponense) hemocyte adaptation to hypoxic conditions Sun, Xichao

299 1 p.
artikel
34 GLUT1 is a highly efficient L-fucose transporter Ng, Bobby G.

299 1 p.
artikel
35 Hydroxylation site–specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: Implications for SREBP-2 and LXR Saito, Hodaka

299 1 p.
artikel
36 Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80 Kang-Pettinger, Tara

299 1 p.
artikel
37 Identification of an inhibitory domain in GTPase-activating protein p190RhoGAP responsible for masking its functional GAP domain Héraud, Capucine

299 1 p.
artikel
38 IFITM proteins: Understanding their diverse roles in viral infection, cancer, and immunity Gómez-Herranz, Maria

299 1 p.
artikel
39 Impact of inherent biases built into proteomic techniques: Proximity labeling and affinity capture compared Moreira, Claudia Maria do Nascimento

299 1 p.
artikel
40 Intrinsically disordered regions that drive phase separation form a robustly distinct protein class Ibrahim, Ayyam Y.

299 1 p.
artikel
41 Kinetics of DNA strand transfer between polymerase and proofreading exonuclease active sites regulates error correction during high-fidelity replication Dangerfield, Tyler L.

299 1 p.
artikel
42 Lack of ApoE inhibits ADan amyloidosis in a mouse model of familial Danish dementia Fernandez, Anllely

299 1 p.
artikel
43 Leucine 434 is essential for docosahexaenoic acid–induced augmentation of L-glutamate transporter current Takahashi, Kanako

299 1 p.
artikel
44 Mapping the KRAS proteoform landscape in colorectal cancer identifies truncated KRAS4B that decreases MAPK signaling Adams, Lauren M.

299 1 p.
artikel
45 Mechanistic insights into the nickel-dependent allosteric response of the Helicobacter pylori NikR transcription factor Baksh, Karina A.

299 1 p.
artikel
46 Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11 Thibodeau, Matthew C.

299 1 p.
artikel
47 Nanobody derived using a peptide epitope from the spike protein receptor-binding motif inhibits entry of SARS-CoV-2 variants Mendon, Nivya

299 1 p.
artikel
48 Negative cooperativity underlies dynamic assembly of the Par complex regulators Cdc42 and Par-3 Vargas, Elizabeth

299 1 p.
artikel
49 Neutron crystallography and quantum chemical analysis of bilin reductase PcyA mutants reveal substrate and catalytic residue protonation states Joutsuka, Tatsuya

299 1 p.
artikel
50 Next-generation retinoid X receptor agonists increase ATRA signaling in organotypic epithelium cultures and have distinct effects on receptor dynamics Melo, Nathalia

299 1 p.
artikel
51 Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine Shang, Qin

299 1 p.
artikel
52 NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet Vickers, Schuyler D.

299 1 p.
artikel
53 Obtaining the necessary molybdenum cofactor for sulfite oxidase activity in the nematode Caenorhabditis elegans surprisingly involves a dietary source Oliphant, Kevin D.

299 1 p.
artikel
54 Off the deep end: What can deep learning do for the gene expression field? Raicu, Ana-Maria

299 1 p.
artikel
55 Oxidative stress in the mitochondrial matrix underlies ischemia/reperfusion-induced mitochondrial instability Solhjoo, Soroosh

299 1 p.
artikel
56 Phosphatidylinositol (3,5)-bisphosphate machinery regulates neurite thickness through neuron-specific endosomal protein NSG1/NEEP21 Qi, Lijuan

299 1 p.
artikel
57 Phosphorylation-dependent interactions of myosin-binding protein C and troponin coordinate the myofilament response to protein kinase A Sevrieva, Ivanka R.

299 1 p.
artikel
58 Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis Baskaran, Pranetha

299 1 p.
artikel
59 Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function Butler, Andrew S.

299 1 p.
artikel
60 Proteomics analysis uncovers plasminogen activator PLAU as a target of the STING pathway for suppression of cancer cell migration and invasion Tan, Jingmin

299 1 p.
artikel
61 Pumping the brakes: A noncanonical RNA-binding domain in FMRP stalls elongating ribosomes Young-Baird, Sara K.

299 1 p.
artikel
62 rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues selective disease features in Smith-Magenis syndrome mice Chang, Hao-Cheng

299 1 p.
artikel
63 Rapid excision of oxidized adenine by human thymine DNA glycosylase Servius, Hardler W.

299 1 p.
artikel
64 Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway Franklin, Derek A.

299 1 p.
artikel
65 RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs Yamamoto, Hiroto

299 1 p.
artikel
66 S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme–substrate interaction Butler, Liam

299 1 p.
artikel
67 Seawater fish use an electrogenic boric acid transporter, Slc4a11A, for boric acid excretion by the kidney Kato, Akira

299 1 p.
artikel
68 SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer Ramakrishnan, Aravinda-Bharathi

299 1 p.
artikel
69 Structure of a dimeric photosystem II complex from a cyanobacterium acclimated to far-red light Gisriel, Christopher J.

299 1 p.
artikel
70 Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties Toyama, Yuki

299 1 p.
artikel
71 Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action Chan, Jocelyn

299 1 p.
artikel
72 Temperature instability of a mutation at a multidomain junction in Na,K-ATPase isoform ATP1A3 (p.Arg756His) produces a fever-induced neurological syndrome Arystarkhova, Elena

299 1 p.
artikel
73 The AF-2 cofactor binding region is key for the selective SUMOylation of estrogen receptor alpha by antiestrogens Vallet, Amandine

299 1 p.
artikel
74 The bacteriophage lambda integrase catalytic domain can be modified to act with the regulatory domain as a recombination-competent binary recombinase Williams, Joe D.

299 1 p.
artikel
75 The carboxyl-terminal TSP1-homology domain is the biologically active effector peptide of matricellular protein CCN5 that counteracts profibrotic CCN2 Zolfaghari, Sima

299 1 p.
artikel
76 The crystal structure of the EspB-EspK virulence factor-chaperone complex suggests an additional type VII secretion mechanism in Mycobacterium tuberculosis Gijsbers, Abril

299 1 p.
artikel
77 The crystal structure of Vibrio cholerae (6-4) photolyase reveals interactions with cofactors and a DNA-binding region Cakilkaya, Baris

299 1 p.
artikel
78 The fates of internalized NaV1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation Higerd-Rusli, Grant P.

299 1 p.
artikel
79 The inhibitor of κB kinase β (IKKβ) phosphorylates IκBα twice in a single binding event through a sequential mechanism Stephenson, Anthony A.

299 1 p.
artikel
80 The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase γ Johnson, Laura C.

299 1 p.
artikel
81 The permanently chaperone-active small heat shock protein Hsp17 from Caenorhabditis elegans exhibits topological separation of its N-terminal regions Strauch, Annika

299 1 p.
artikel
82 The SDBC is active in quenching oxidative conditions and bridges the cell envelope layers in Deinococcus radiodurans Farci, Domenica

299 1 p.
artikel
83 The structure of caseinolytic protease subunit ClpP2 reveals a functional model of the caseinolytic protease system from Chlamydia trachomatis Azadmanesh, Jahaun

299 1 p.
artikel
84 Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer Su, Yingjie

299 1 p.
artikel
85 Yeast 9-1-1 complex acts as a sliding clamp for DNA synthesis by DNA polymerase ε Acharya, Narottam

299 1 p.
artikel
86 Zinc dynamics regulate early ovarian follicle development Chen, Yu-Ying

299 1 p.
artikel
87 Zinc-finger protein CXXC5 promotes breast carcinogenesis by regulating the TSC1/mTOR signaling pathway Wang, Wenjuan

299 1 p.
artikel
                             87 gevonden resultaten
 
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