nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A broad specificity β-propeller enzyme from Rhodopseudomonas palustris that hydrolyzes many lactones including γ-valerolactone
|
Hall, Benjamin W. |
|
|
299 |
1 |
p. |
artikel |
2 |
Acetyl-CoA carboxylase 1 depletion suppresses de novo fatty acid synthesis and mitochondrial β-oxidation in castration-resistant prostate cancer cells
|
Liu, Shaoyou |
|
|
299 |
1 |
p. |
artikel |
3 |
Activation of amygdala prokineticin receptor 2 neurons drives the anorexigenic activity of the neuropeptide PK2
|
Yin, Terry C. |
|
|
299 |
1 |
p. |
artikel |
4 |
Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors
|
Lee, Ee-Soo |
|
|
299 |
1 |
p. |
artikel |
5 |
A midposition NOTCH3 truncation in inherited cerebral small vessel disease may affect the protein interactome
|
Lee, Soo Jung |
|
|
299 |
1 |
p. |
artikel |
6 |
An evolutionarily conserved N-terminal leucine is essential for MX1 GTPase antiviral activity against different families of RNA viruses
|
McKellar, Joe |
|
|
299 |
1 |
p. |
artikel |
7 |
A peptide derived from adaptor protein STAP-2 inhibits tumor progression by downregulating epidermal growth factor receptor signaling
|
Maemoto, Taiga |
|
|
299 |
1 |
p. |
artikel |
8 |
Application of mutational profiling: New functional analyses reveal the tRNA recognition mechanism of tRNA m1A22 methyltransferase
|
Yamagami, Ryota |
|
|
299 |
1 |
p. |
artikel |
9 |
Archeal tRNA meets biotechnology: From vaccines to genetic code expansion
|
Ribas de Pouplana, Lluís |
|
|
299 |
1 |
p. |
artikel |
10 |
Arginine-rich C9ORF72 ALS proteins stall ribosomes in a manner distinct from a canonical ribosome-associated quality control substrate
|
Kriachkov, Viacheslav |
|
|
299 |
1 |
p. |
artikel |
11 |
A splicing-dependent ER retention signal regulates surface expression of the mechanosensitive TMEM63B cation channel
|
Wu, Dan |
|
|
299 |
1 |
p. |
artikel |
12 |
A tumor microenvironment-activated metal-organic framework–based nanoplatform for amplified oxidative stress–induced enhanced chemotherapy
|
Li, Bo |
|
|
299 |
1 |
p. |
artikel |
13 |
Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer
|
Acharya, Srijan |
|
|
299 |
1 |
p. |
artikel |
14 |
BY-kinases: Protein tyrosine kinases like no other
|
Hajredini, Fatlum |
|
|
299 |
1 |
p. |
artikel |
15 |
Calmodulin variant E140G associated with long QT syndrome impairs CaMKIIδ autophosphorylation and L-type calcium channel inactivation
|
Prakash, Ohm |
|
|
299 |
1 |
p. |
artikel |
16 |
Characterization of the Escherichia coli XPD/Rad3 iron-sulfur helicase YoaA in complex with the DNA polymerase III clamp loader subunit chi (χ)
|
Weeks-Pollenz, Savannah J. |
|
|
299 |
1 |
p. |
artikel |
17 |
Correction: Parkin ubiquitinates TAR-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6)
|
Hebron, Michaeline L. |
|
|
299 |
1 |
p. |
artikel |
18 |
Correction: Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation
|
Nagy, Zoltán Attila |
|
|
299 |
1 |
p. |
artikel |
19 |
Correction: The Wnt target protein Peter Pan defines a novel p53-independent nucleolar stress-response pathway
|
Pfister, Astrid S. |
|
|
299 |
1 |
p. |
artikel |
20 |
Cover
|
|
|
|
299 |
1 |
p. |
artikel |
21 |
Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction
|
Kulczyk, Arkadiusz W. |
|
|
299 |
1 |
p. |
artikel |
22 |
Deep mutational analysis of elongation factor eEF2 residues implicated in human disease to identify functionally important contacts with the ribosome
|
Olson, Alexandra N. |
|
|
299 |
1 |
p. |
artikel |
23 |
Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains
|
Hay, Iain M. |
|
|
299 |
1 |
p. |
artikel |
24 |
Deubiquitinase USP2 stabilizes the MRE11–RAD50–NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1
|
Kim, Hyunsup |
|
|
299 |
1 |
p. |
artikel |
25 |
Difluoromethyl-1,3,4-oxadiazoles are slow-binding substrate analog inhibitors of histone deacetylase 6 with unprecedented isotype selectivity
|
Cellupica, Edoardo |
|
|
299 |
1 |
p. |
artikel |
26 |
Diptoindonesin G, a new Hsp90 drug
|
Wickramaratne, Anushka |
|
|
299 |
1 |
p. |
artikel |
27 |
DNA damage to bone marrow stromal cells by antileukemia drugs induces chemoresistance in acute myeloid leukemia via paracrine FGF10–FGFR2 signaling
|
Yu, Shuang |
|
|
299 |
1 |
p. |
artikel |
28 |
DNA repair protein RAD52 is required for protecting G-quadruplexes in mammalian cells
|
Liu, Shuo |
|
|
299 |
1 |
p. |
artikel |
29 |
Exploration of the cysteine reactivity of human inducible Hsp70 and cognate Hsc70
|
Hong, Zhouping |
|
|
299 |
1 |
p. |
artikel |
30 |
Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth
|
Wisniewski, David J. |
|
|
299 |
1 |
p. |
artikel |
31 |
Free fatty acids stabilize integrin β1 via S-nitrosylation to promote monocyte–endothelial adhesion
|
Yao, Qinyu |
|
|
299 |
1 |
p. |
artikel |
32 |
Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles
|
Lee, Lindsey A. |
|
|
299 |
1 |
p. |
artikel |
33 |
Glucose transporter GLUT1 expression is important for oriental river prawn (Macrobrachium nipponense) hemocyte adaptation to hypoxic conditions
|
Sun, Xichao |
|
|
299 |
1 |
p. |
artikel |
34 |
GLUT1 is a highly efficient L-fucose transporter
|
Ng, Bobby G. |
|
|
299 |
1 |
p. |
artikel |
35 |
Hydroxylation site–specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: Implications for SREBP-2 and LXR
|
Saito, Hodaka |
|
|
299 |
1 |
p. |
artikel |
36 |
Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80
|
Kang-Pettinger, Tara |
|
|
299 |
1 |
p. |
artikel |
37 |
Identification of an inhibitory domain in GTPase-activating protein p190RhoGAP responsible for masking its functional GAP domain
|
Héraud, Capucine |
|
|
299 |
1 |
p. |
artikel |
38 |
IFITM proteins: Understanding their diverse roles in viral infection, cancer, and immunity
|
Gómez-Herranz, Maria |
|
|
299 |
1 |
p. |
artikel |
39 |
Impact of inherent biases built into proteomic techniques: Proximity labeling and affinity capture compared
|
Moreira, Claudia Maria do Nascimento |
|
|
299 |
1 |
p. |
artikel |
40 |
Intrinsically disordered regions that drive phase separation form a robustly distinct protein class
|
Ibrahim, Ayyam Y. |
|
|
299 |
1 |
p. |
artikel |
41 |
Kinetics of DNA strand transfer between polymerase and proofreading exonuclease active sites regulates error correction during high-fidelity replication
|
Dangerfield, Tyler L. |
|
|
299 |
1 |
p. |
artikel |
42 |
Lack of ApoE inhibits ADan amyloidosis in a mouse model of familial Danish dementia
|
Fernandez, Anllely |
|
|
299 |
1 |
p. |
artikel |
43 |
Leucine 434 is essential for docosahexaenoic acid–induced augmentation of L-glutamate transporter current
|
Takahashi, Kanako |
|
|
299 |
1 |
p. |
artikel |
44 |
Mapping the KRAS proteoform landscape in colorectal cancer identifies truncated KRAS4B that decreases MAPK signaling
|
Adams, Lauren M. |
|
|
299 |
1 |
p. |
artikel |
45 |
Mechanistic insights into the nickel-dependent allosteric response of the Helicobacter pylori NikR transcription factor
|
Baksh, Karina A. |
|
|
299 |
1 |
p. |
artikel |
46 |
Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11
|
Thibodeau, Matthew C. |
|
|
299 |
1 |
p. |
artikel |
47 |
Nanobody derived using a peptide epitope from the spike protein receptor-binding motif inhibits entry of SARS-CoV-2 variants
|
Mendon, Nivya |
|
|
299 |
1 |
p. |
artikel |
48 |
Negative cooperativity underlies dynamic assembly of the Par complex regulators Cdc42 and Par-3
|
Vargas, Elizabeth |
|
|
299 |
1 |
p. |
artikel |
49 |
Neutron crystallography and quantum chemical analysis of bilin reductase PcyA mutants reveal substrate and catalytic residue protonation states
|
Joutsuka, Tatsuya |
|
|
299 |
1 |
p. |
artikel |
50 |
Next-generation retinoid X receptor agonists increase ATRA signaling in organotypic epithelium cultures and have distinct effects on receptor dynamics
|
Melo, Nathalia |
|
|
299 |
1 |
p. |
artikel |
51 |
Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine
|
Shang, Qin |
|
|
299 |
1 |
p. |
artikel |
52 |
NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet
|
Vickers, Schuyler D. |
|
|
299 |
1 |
p. |
artikel |
53 |
Obtaining the necessary molybdenum cofactor for sulfite oxidase activity in the nematode Caenorhabditis elegans surprisingly involves a dietary source
|
Oliphant, Kevin D. |
|
|
299 |
1 |
p. |
artikel |
54 |
Off the deep end: What can deep learning do for the gene expression field?
|
Raicu, Ana-Maria |
|
|
299 |
1 |
p. |
artikel |
55 |
Oxidative stress in the mitochondrial matrix underlies ischemia/reperfusion-induced mitochondrial instability
|
Solhjoo, Soroosh |
|
|
299 |
1 |
p. |
artikel |
56 |
Phosphatidylinositol (3,5)-bisphosphate machinery regulates neurite thickness through neuron-specific endosomal protein NSG1/NEEP21
|
Qi, Lijuan |
|
|
299 |
1 |
p. |
artikel |
57 |
Phosphorylation-dependent interactions of myosin-binding protein C and troponin coordinate the myofilament response to protein kinase A
|
Sevrieva, Ivanka R. |
|
|
299 |
1 |
p. |
artikel |
58 |
Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis
|
Baskaran, Pranetha |
|
|
299 |
1 |
p. |
artikel |
59 |
Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function
|
Butler, Andrew S. |
|
|
299 |
1 |
p. |
artikel |
60 |
Proteomics analysis uncovers plasminogen activator PLAU as a target of the STING pathway for suppression of cancer cell migration and invasion
|
Tan, Jingmin |
|
|
299 |
1 |
p. |
artikel |
61 |
Pumping the brakes: A noncanonical RNA-binding domain in FMRP stalls elongating ribosomes
|
Young-Baird, Sara K. |
|
|
299 |
1 |
p. |
artikel |
62 |
rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues selective disease features in Smith-Magenis syndrome mice
|
Chang, Hao-Cheng |
|
|
299 |
1 |
p. |
artikel |
63 |
Rapid excision of oxidized adenine by human thymine DNA glycosylase
|
Servius, Hardler W. |
|
|
299 |
1 |
p. |
artikel |
64 |
Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway
|
Franklin, Derek A. |
|
|
299 |
1 |
p. |
artikel |
65 |
RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs
|
Yamamoto, Hiroto |
|
|
299 |
1 |
p. |
artikel |
66 |
S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme–substrate interaction
|
Butler, Liam |
|
|
299 |
1 |
p. |
artikel |
67 |
Seawater fish use an electrogenic boric acid transporter, Slc4a11A, for boric acid excretion by the kidney
|
Kato, Akira |
|
|
299 |
1 |
p. |
artikel |
68 |
SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer
|
Ramakrishnan, Aravinda-Bharathi |
|
|
299 |
1 |
p. |
artikel |
69 |
Structure of a dimeric photosystem II complex from a cyanobacterium acclimated to far-red light
|
Gisriel, Christopher J. |
|
|
299 |
1 |
p. |
artikel |
70 |
Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties
|
Toyama, Yuki |
|
|
299 |
1 |
p. |
artikel |
71 |
Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action
|
Chan, Jocelyn |
|
|
299 |
1 |
p. |
artikel |
72 |
Temperature instability of a mutation at a multidomain junction in Na,K-ATPase isoform ATP1A3 (p.Arg756His) produces a fever-induced neurological syndrome
|
Arystarkhova, Elena |
|
|
299 |
1 |
p. |
artikel |
73 |
The AF-2 cofactor binding region is key for the selective SUMOylation of estrogen receptor alpha by antiestrogens
|
Vallet, Amandine |
|
|
299 |
1 |
p. |
artikel |
74 |
The bacteriophage lambda integrase catalytic domain can be modified to act with the regulatory domain as a recombination-competent binary recombinase
|
Williams, Joe D. |
|
|
299 |
1 |
p. |
artikel |
75 |
The carboxyl-terminal TSP1-homology domain is the biologically active effector peptide of matricellular protein CCN5 that counteracts profibrotic CCN2
|
Zolfaghari, Sima |
|
|
299 |
1 |
p. |
artikel |
76 |
The crystal structure of the EspB-EspK virulence factor-chaperone complex suggests an additional type VII secretion mechanism in Mycobacterium tuberculosis
|
Gijsbers, Abril |
|
|
299 |
1 |
p. |
artikel |
77 |
The crystal structure of Vibrio cholerae (6-4) photolyase reveals interactions with cofactors and a DNA-binding region
|
Cakilkaya, Baris |
|
|
299 |
1 |
p. |
artikel |
78 |
The fates of internalized NaV1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation
|
Higerd-Rusli, Grant P. |
|
|
299 |
1 |
p. |
artikel |
79 |
The inhibitor of κB kinase β (IKKβ) phosphorylates IκBα twice in a single binding event through a sequential mechanism
|
Stephenson, Anthony A. |
|
|
299 |
1 |
p. |
artikel |
80 |
The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase γ
|
Johnson, Laura C. |
|
|
299 |
1 |
p. |
artikel |
81 |
The permanently chaperone-active small heat shock protein Hsp17 from Caenorhabditis elegans exhibits topological separation of its N-terminal regions
|
Strauch, Annika |
|
|
299 |
1 |
p. |
artikel |
82 |
The SDBC is active in quenching oxidative conditions and bridges the cell envelope layers in Deinococcus radiodurans
|
Farci, Domenica |
|
|
299 |
1 |
p. |
artikel |
83 |
The structure of caseinolytic protease subunit ClpP2 reveals a functional model of the caseinolytic protease system from Chlamydia trachomatis
|
Azadmanesh, Jahaun |
|
|
299 |
1 |
p. |
artikel |
84 |
Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer
|
Su, Yingjie |
|
|
299 |
1 |
p. |
artikel |
85 |
Yeast 9-1-1 complex acts as a sliding clamp for DNA synthesis by DNA polymerase ε
|
Acharya, Narottam |
|
|
299 |
1 |
p. |
artikel |
86 |
Zinc dynamics regulate early ovarian follicle development
|
Chen, Yu-Ying |
|
|
299 |
1 |
p. |
artikel |
87 |
Zinc-finger protein CXXC5 promotes breast carcinogenesis by regulating the TSC1/mTOR signaling pathway
|
Wang, Wenjuan |
|
|
299 |
1 |
p. |
artikel |