Digitale Bibliotheek
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                             94 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A conserved set of mutations for stabilizing soluble envelope protein dimers from dengue and Zika viruses to advance the development of subunit vaccines Phan, Thanh T.N.

298 7 p.
artikel
2 Adipose-derived exosomes block muscular stem cell proliferation in aged mouse by delivering miRNA Let-7d-3p that targets transcription factor HMGA2 Itokazu, Maki

298 7 p.
artikel
3 A metal ion–dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase Webb, Chaille T.

298 7 p.
artikel
4 A multi-omics analysis reveals that the lysine deacetylase ABHD14B influences glucose metabolism in mammals Rajendran, Abinaya

298 7 p.
artikel
5 A novel antiproliferative PKCα-Ras-ERK signaling axis in intestinal epithelial cells Kaur, Navneet

298 7 p.
artikel
6 A novel LncRNA PTH-AS upregulates interferon-related DNA damage resistance signature genes and promotes metastasis in human breast cancer xenografts Akimoto, Miho

298 7 p.
artikel
7 A novel tubulin inhibitor, 6h, suppresses tumor-associated angiogenesis and shows potent antitumor activity against non–small cell lung cancers Liu, Zi

298 7 p.
artikel
8 A Spef1-interacting microtubule quartet protein in Trypanosoma brucei promotes flagellar inheritance by regulating basal body segregation Pham, Kieu T.M.

298 7 p.
artikel
9 A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome Hsiao, Jeffrey C.

298 7 p.
artikel
10 Cardiac ventricular myosin and slow skeletal myosin exhibit dissimilar chemomechanical properties despite bearing the same myosin heavy chain isoform Wang, Tianbang

298 7 p.
artikel
11 Characterization of a [4Fe-4S]-dependent LarE sulfur insertase that facilitates nickel-pincer nucleotide cofactor biosynthesis in Thermotoga maritima Chatterjee, Shramana

298 7 p.
artikel
12 Characterization of a novel β-alanine biosynthetic pathway consisting of promiscuous metabolic enzymes Perchat, Nadia

298 7 p.
artikel
13 Clinical, genetic, and functional characterization of the glycine receptor β-subunit A455P variant in a family affected by hyperekplexia syndrome Aboheimed, Ghada I.

298 7 p.
artikel
14 Comparative analysis defines a broader FMRFamide-gated sodium channel family and determinants of neuropeptide sensitivity Dandamudi, Mowgli

298 7 p.
artikel
15 Competitive inhibition of the classical complement pathway using exogenous single-chain C1q recognition proteins Vadászi, Henrietta

298 7 p.
artikel
16 Conformational flexibility in carbapenem hydrolysis drives substrate specificity of the class D carbapenemase OXA-24/40 Mitchell, Joshua M.

298 7 p.
artikel
17 Correction: Exostosin glycosyltransferase 1 reduces porcine reproductive and respiratory syndrome virus infection through proteasomal degradation of nsp3 and nsp5 Zhang, Xiaoxiao

298 7 p.
artikel
18 Cover
298 7 p.
artikel
19 Critical roles of protein disulfide isomerases in balancing proteostasis in the nervous system Medinas, Danilo B.

298 7 p.
artikel
20 Cross-seeding of WT amyloid-β with Arctic but not Italian familial mutants accelerates fibril formation in Alzheimer's disease Liang, Ruina

298 7 p.
artikel
21 Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways Aoki, Mizuki

298 7 p.
artikel
22 Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding Asa, Minori

298 7 p.
artikel
23 c-Src–mediated phosphorylation and activation of kinesin KIF1C promotes elongation of invadopodia in cancer cells Saji, Takeshi

298 7 p.
artikel
24 3D cryo-EM imaging of bacterial flagella: Novel structural and mechanistic insights into cell motility Mondino, Sonia

298 7 p.
artikel
25 Delineation of a minimal topoisomerase II binding protein 1 for regulated activation of ATR at DNA double-strand breaks Ruis, Kenna

298 7 p.
artikel
26 Development of a universal antibiotic resistance screening reporter for improving efficiency of cytosine and adenine base editing Ma, Lixia

298 7 p.
artikel
27 Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons Han, Ye

298 7 p.
artikel
28 Distinct functional roles for the M4 α-helix from each homologous subunit in the heteropentameric ligand-gated ion channel nAChR Thompson, Mackenzie J.

298 7 p.
artikel
29 Diverse reaction behaviors of artificial ubiquinones in mitochondrial respiratory complex I Uno, Shinpei

298 7 p.
artikel
30 Elesclomol elevates cellular and mitochondrial iron levels by delivering copper to the iron import machinery Garza, Natalie M.

298 7 p.
artikel
31 Extended conformational states dominate the Hsp90 chaperone dynamics Jussupow, Alexander

298 7 p.
artikel
32 Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/β-catenin signaling in obstructed kidneys in vivo Zhang, Yu

298 7 p.
artikel
33 FOXF2 oppositely regulates stemness in luminal and basal-like breast cancer cells through the Wnt/beta-catenin pathway Zhang, Xiao

298 7 p.
artikel
34 Fringe GlcNAc-transferases differentially extend O-fucose on endogenous NOTCH1 in mouse activated T cells Matsumoto, Kenjiroo

298 7 p.
artikel
35 Glycogen-autophagy: Molecular machinery and cellular mechanisms of glycophagy Koutsifeli, Parisa

298 7 p.
artikel
36 Guanine nucleotide exchange factor DOCK11-binding peptide fused with a single chain antibody inhibits hepatitis B virus infection and replication Ide, Mayuko

298 7 p.
artikel
37 High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP Klemm, Bradley P.

298 7 p.
artikel
38 Histone methyltransferase Dot1L recruits O-GlcNAc transferase to target chromatin sites to regulate histone O-GlcNAcylation Xu, Bo

298 7 p.
artikel
39 Hydrophobic mismatch is a key factor in protein transport across lipid bilayer membranes via the Tat pathway Hao, Binhan

298 7 p.
artikel
40 Hypoxia-inducible factor-1α and poly [ADP ribose] polymerase 1 cooperatively regulate Notch3 expression under hypoxia via a noncanonical mechanism Nakamura, Hideaki

298 7 p.
artikel
41 Identification and functional implications of pseudouridine RNA modification on small noncoding RNAs in the mammalian pathogen Trypanosoma brucei Rajan, K. Shanmugha

298 7 p.
artikel
42 Ingestion of single guide RNAs induces gene overexpression and extends lifespan in Caenorhabditis elegans via CRISPR activation Fischer, Fabian

298 7 p.
artikel
43 Inhibitory and stimulatory micropeptides preferentially bind to different conformations of the cardiac calcium pump Cleary, Sean R.

298 7 p.
artikel
44 Interplay between H3K36me3, methyltransferase SETD2, and mismatch recognition protein MutSα facilitates processing of oxidative DNA damage in human cells Guo, Sida

298 7 p.
artikel
45 Intracellular localization of the proteasome in response to stress conditions Enenkel, Cordula

298 7 p.
artikel
46 In vitro eradication of abasic site-mediated DNA–peptide/protein cross-links by Escherichia coli long-patch base excision repair Bryan, Cameron

298 7 p.
artikel
47 Iron nitrosyl complexes are formed from nitrite in the human placenta Mukosera, George T.

298 7 p.
artikel
48 Iron-regulated assembly of the cytosolic iron–sulfur cluster biogenesis machinery Fan, Xiaorui

298 7 p.
artikel
49 Maintaining the thyroid gland in mutant thyroglobulin–induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood Zhang, Xiaohan

298 7 p.
artikel
50 Mechanisms of phosphatidylserine influence on viral production: A computational model of Ebola virus matrix protein assembly Liu, Xiao

298 7 p.
artikel
51 Mechanistic insights into accelerated α-synuclein aggregation mediated by human microbiome-associated functional amyloids Bhoite, Sujeet S.

298 7 p.
artikel
52 Membrane translocation of folded proteins Pei, Dehua

298 7 p.
artikel
53 miR-134-5p inhibits osteoclastogenesis through a novel miR-134-5p/Itgb1/MAPK pathway Huang, Meng

298 7 p.
artikel
54 mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine Alam, Mahabub

298 7 p.
artikel
55 Multifaceted regulation of the sumoylation of the Sgs1 DNA helicase Li, Shibai

298 7 p.
artikel
56 Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential Zhang, Min

298 7 p.
artikel
57 Oxidative stress activates transcription of Salmonella pathogenicity island-2 genes in macrophages Kim, Ju-Sim

298 7 p.
artikel
58 PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c Dogan, Asli E.

298 7 p.
artikel
59 Peroxiredoxin IV plays a critical role in cancer cell growth and radioresistance through the activation of the Akt/GSK3 signaling pathways Ding, Na

298 7 p.
artikel
60 Phosphatidic acid species 34:1 mediates expression of the myo-inositol 3-phosphate synthase gene INO1 for lipid synthesis in yeast Gaspar, Maria Laura

298 7 p.
artikel
61 Phosphatidylinositol phosphates modulate interactions between the StarD4 sterol trafficking protein and lipid membranes Zhang, Xiaoxue

298 7 p.
artikel
62 Phosphatidylserine externalization by apoptotic cells is dispensable for specific recognition leading to innate apoptotic immune responses Gomes, Marta T.

298 7 p.
artikel
63 Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses Loef, Evert J.

298 7 p.
artikel
64 Probe ultrasonification of egg yolk plasma forms low-density lipoprotein nanoparticles that efficiently protect canine semen during cryofreezing Anastácio da Silva, Edenara

298 7 p.
artikel
65 Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intracellular and extracellular regulatory circuits Saitoski, Kevin

298 7 p.
artikel
66 Protein interaction networks in neurodegenerative diseases: From physiological function to aggregation Calabrese, Gaetano

298 7 p.
artikel
67 Recognition of 3′ nucleotide context and stop codon readthrough are determined during mRNA translation elongation Biziaev, Nikita

298 7 p.
artikel
68 Redox regulation by TXNRD3 during epididymal maturation underlies capacitation-associated mitochondrial activity and sperm motility in mice Wang, Huafeng

298 7 p.
artikel
69 Regulation of calcium homeostasis and flux between the endoplasmic reticulum and the cytosol Daverkausen-Fischer, Lea

298 7 p.
artikel
70 Regulation of the lysosome by sphingolipids: Potential role in aging Tang, Haiqing

298 7 p.
artikel
71 Retinoid orphan nuclear receptor alpha (RORα) suppresses the epithelial–mesenchymal transition (EMT) by directly repressing Snail transcription Xiong, Gaofeng

298 7 p.
artikel
72 Selective PPARδ agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway Kouno, Tetsuya

298 7 p.
artikel
73 SifR is an Rrf2-family quinone sensor associated with catechol iron uptake in Streptococcus pneumoniae D39 Zhang, Yifan

298 7 p.
artikel
74 SmiA is a hybrid priming/scaffolding adaptor for the LonA protease in Bacillus subtilis Olney, Stephen G.

298 7 p.
artikel
75 Structural and mechanistic insights into the inhibition of type I-F CRISPR-Cas system by anti-CRISPR protein AcrIF23 Ren, Junhui

298 7 p.
artikel
76 Structural basis for c-di-AMP–dependent regulation of the bacterial stringent response by receptor protein DarB Heidemann, Jana L.

298 7 p.
artikel
77 Structural characterization of fungus-specific histone deacetylase Hos3 provides insights into developing selective inhibitors with antifungal activity Pang, Ningning

298 7 p.
artikel
78 Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response Bisiak, Francesco

298 7 p.
artikel
79 Structure-based interface engineering methodology in designing a thermostable amylose-forming transglucosylase Tian, Yuqing

298 7 p.
artikel
80 Structure of the second phosphoubiquitin–binding site in parkin Fakih, Rayan

298 7 p.
artikel
81 Suppressor mutations in Escherichia coli RNA polymerase alter transcription initiation but do not affect translesion RNA synthesis in vitro Miropolskaya, Nataliya

298 7 p.
artikel
82 TET2–BCLAF1 transcription repression complex epigenetically regulates the expression of colorectal cancer gene Ascl2 via methylation of its promoter Shang, Yangyang

298 7 p.
artikel
83 The neurosteroid pregnenolone is synthesized by a mitochondrial P450 enzyme other than CYP11A1 in human glial cells Lin, Yiqi Christina

298 7 p.
artikel
84 The regulatory role of the Aspergillus flavus core retromer complex in aflatoxin metabolism Wang, Sen

298 7 p.
artikel
85 The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors Murphy, Robert D.

298 7 p.
artikel
86 TIP60 acts as a regulator of genes involved in filopodia formation and cell migration during wound healing Dubey, Shraddha

298 7 p.
artikel
87 Transcription factor GATA2 may potentiate follicle-stimulating hormone production in mice via induction of the BMP antagonist gremlin in gonadotrope cells Schang, Gauthier

298 7 p.
artikel
88 Translation initiation factor eIF3a regulates glucose metabolism and cell proliferation via promoting small GTPase Rheb synthesis and AMPK activation Ma, Shijie

298 7 p.
artikel
89 Tumor protein D54 binds intracellular nanovesicles via an extended amphipathic region Reynaud, Antoine

298 7 p.
artikel
90 Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition Chu, Kit-Yee

298 7 p.
artikel
91 Vibrio splendidus flagellin C binds tropomodulin to induce p38 MAPK-mediated p53-dependent coelomocyte apoptosis in Echinodermata Dai, Fa

298 7 p.
artikel
92 Withdrawal: Mitochondrial pyruvate carrier blockade results in decreased osteoclastogenesis and bone resorption via regulating mitochondrial energy production Guo, Qian

298 7 p.
artikel
93 Withdrawal: Reactive oxygen species (ROS) mediate p300-dependent STAT1 protein interaction with peroxisome proliferator-activated receptor (PPAR)-γ in CD36 protein expression and foam cell formation Kotla, Sivareddy

298 7 p.
artikel
94 Withdrawal: The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer Wang, Jianhua

298 7 p.
artikel
                             94 gevonden resultaten
 
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