| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
AAA-ATPase valosin-containing protein binds the transcription factor SREBP1 and promotes its proteolytic activation by rhomboid protease RHBDL4
|
Shibuya, Koji
|
|
|
298 |
6 |
p.
|
artikel
|
| 2 |
A Ca2+-binding motif underlies the unusual properties of certain photosynthetic bacterial core light-harvesting complexes
|
Tani, Kazutoshi
|
|
|
298 |
6 |
p.
|
artikel
|
| 3 |
Activation of the adhesion G protein–coupled receptor GPR133 by antibodies targeting its N-terminus
|
Stephan, Gabriele
|
|
|
298 |
6 |
p.
|
artikel
|
| 4 |
Activity-dependent modulation of neuronal KV channels by retinoic acid enhances CaV channel activity
|
de Hoog, Eric
|
|
|
298 |
6 |
p.
|
artikel
|
| 5 |
Allosteric coupling between transmembrane segment 4 and the selectivity filter of TALK1 potassium channels regulates their gating by extracellular pH
|
Tsai, Wen-Hao
|
|
|
298 |
6 |
p.
|
artikel
|
| 6 |
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation
|
Ji, Renpeng
|
|
|
298 |
6 |
p.
|
artikel
|
| 7 |
A mechanochemical model of the forward/backward movement of motor protein kinesin-1
|
Shen, Beibei
|
|
|
298 |
6 |
p.
|
artikel
|
| 8 |
A membrane ATPase without transporter activity
|
Oldach, Laurel
|
|
|
298 |
6 |
p.
|
artikel
|
| 9 |
Amino acids in transmembrane helix 1 confer major functional differences between human and mouse orthologs of the polyspecific membrane transporter OCT1
|
Meyer, Marleen J.
|
|
|
298 |
6 |
p.
|
artikel
|
| 10 |
2-Aminoacrylate stress damages diverse PLP-dependent enzymes in vivo
|
Shen, Wangchen
|
|
|
298 |
6 |
p.
|
artikel
|
| 11 |
Analysis of functional surfaces on the actin nucleation promoting factor Dip1 required for Arp2/3 complex activation and endocytic actin network assembly
|
Liu, Su-Ling
|
|
|
298 |
6 |
p.
|
artikel
|
| 12 |
A novel Cbx1, PurB, and Sp3 complex mediates long-term silencing of tissue- and lineage-specific genes
|
Baksh, Syeda Samara
|
|
|
298 |
6 |
p.
|
artikel
|
| 13 |
A novel small-molecule selective activator of homomeric GIRK4 channels
|
Cui, Meng
|
|
|
298 |
6 |
p.
|
artikel
|
| 14 |
Antibody recognition of complement factor H reveals a flexible loop involved in atypical hemolytic uremic syndrome pathogenesis
|
Yokoo, Takanori
|
|
|
298 |
6 |
p.
|
artikel
|
| 15 |
Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK
|
Clayton, Natasha S.
|
|
|
298 |
6 |
p.
|
artikel
|
| 16 |
Association of the receptor for activated C-kinase 1 with ribosomes in Plasmodium falciparum
|
Erath, Jessey
|
|
|
298 |
6 |
p.
|
artikel
|
| 17 |
Binding of the erlin1/2 complex to the third intralumenal loop of IP3R1 triggers its ubiquitin-proteasomal degradation
|
Gao, Xiaokong
|
|
|
298 |
6 |
p.
|
artikel
|
| 18 |
Brain-derived neurotrophic factor regulates LYN kinase–mediated myosin light chain kinase activation to modulate nonmuscle myosin II activity in hippocampal neurons
|
Li, Xiaobing
|
|
|
298 |
6 |
p.
|
artikel
|
| 19 |
Calpain-mediated proteolytic production of free amino acids in vascular endothelial cells augments obesity-induced hepatic steatosis
|
Akasu, Risako
|
|
|
298 |
6 |
p.
|
artikel
|
| 20 |
Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain
|
Ghosh, Krishna
|
|
|
298 |
6 |
p.
|
artikel
|
| 21 |
Cellular abundance of sodium phosphate cotransporter SLC20A1/PiT1 and phosphate uptake are controlled post-transcriptionally by ESCRT
|
Zechner, Christoph
|
|
|
298 |
6 |
p.
|
artikel
|
| 22 |
Concerted actions of DnaA complexes with DNA-unwinding sequences within and flanking replication origin oriC promote DnaB helicase loading
|
Sakiyama, Yukari
|
|
|
298 |
6 |
p.
|
artikel
|
| 23 |
Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-β to its receptors, TβRI and TβRII
|
Mukundan, Ananya
|
|
|
298 |
6 |
p.
|
artikel
|
| 24 |
Correction: Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling
|
Artan, Murat
|
|
|
298 |
6 |
p.
|
artikel
|
| 25 |
Cover
|
|
|
|
298 |
6 |
p.
|
artikel
|
| 26 |
Cryo-EM structure of the fatty acid reductase LuxC–LuxE complex provides insights into bacterial bioluminescence
|
Tian, Qingwei
|
|
|
298 |
6 |
p.
|
artikel
|
| 27 |
Deformation of caveolae impacts global transcription and translation processes through relocalization of cavin-1
|
Qifti, Androniqi
|
|
|
298 |
6 |
p.
|
artikel
|
| 28 |
Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase
|
Butrin, Arseniy
|
|
|
298 |
6 |
p.
|
artikel
|
| 29 |
Development of antiviral carbon quantum dots that target the Japanese encephalitis virus envelope protein
|
Chen, Han-Hsiang
|
|
|
298 |
6 |
p.
|
artikel
|
| 30 |
Discovery of two distinct aminoacyl-tRNA synthetase complexes anchored to the Plasmodium surface tRNA import protein
|
Jaramillo Ponce, José R.
|
|
|
298 |
6 |
p.
|
artikel
|
| 31 |
Domain architecture and catalysis of the Staphylococcus aureus fatty acid kinase
|
Subramanian, Chitra
|
|
|
298 |
6 |
p.
|
artikel
|
| 32 |
Dual Cre and Dre recombinases mediate synchronized lineage tracing and cell subset ablation in v ivo
|
Wang, Haixiao
|
|
|
298 |
6 |
p.
|
artikel
|
| 33 |
EGLN1 prolyl hydroxylation of hypoxia-induced transcription factor HIF1α is repressed by SET7-catalyzed lysine methylation
|
Tang, Jinhua
|
|
|
298 |
6 |
p.
|
artikel
|
| 34 |
E3 ligase HUWE1 promotes PDGF D-mediated osteoblastic differentiation of mesenchymal stem cells by effecting polyubiquitination of β-PDGFR
|
Pham, Tri
|
|
|
298 |
6 |
p.
|
artikel
|
| 35 |
Elucidation of physico-chemical principles of high-density lipoprotein–small RNA binding interactions
|
Michell, Danielle L.
|
|
|
298 |
6 |
p.
|
artikel
|
| 36 |
Endothelial expression of human amyloid precursor protein leads to amyloid β in the blood and induces cerebral amyloid angiopathy in knock-in mice
|
Tachida, Yuriko
|
|
|
298 |
6 |
p.
|
artikel
|
| 37 |
Enhanced Orai1-mediated store-operated Ca2+ channel/calpain signaling contributes to high glucose-induced podocyte injury
|
Tao, Yu
|
|
|
298 |
6 |
p.
|
artikel
|
| 38 |
ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1
|
Zhong, Xiaodan
|
|
|
298 |
6 |
p.
|
artikel
|
| 39 |
Evolution of Streptococcus pyogenes has maximized the efficiency of the Sortase A cleavage motif for cell wall transpeptidation
|
Readnour, Bradley M.
|
|
|
298 |
6 |
p.
|
artikel
|
| 40 |
Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins
|
Leissing, Thomas M.
|
|
|
298 |
6 |
p.
|
artikel
|
| 41 |
Fueling genome maintenance: On the versatile roles of NAD+ in preserving DNA integrity
|
Ruszkiewicz, Joanna A.
|
|
|
298 |
6 |
p.
|
artikel
|
| 42 |
Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis
|
Yan, Kaizhou
|
|
|
298 |
6 |
p.
|
artikel
|
| 43 |
Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery
|
Krakovka, Sascha
|
|
|
298 |
6 |
p.
|
artikel
|
| 44 |
Heparin activation of protein Z-dependent protease inhibitor (ZPI) allosterically blocks protein Z activation through an extended heparin-binding site
|
Huang, Xin
|
|
|
298 |
6 |
p.
|
artikel
|
| 45 |
Histone chaperone ASF1 acts with RIF1 to promote DNA end joining in BRCA1-deficient cells
|
Tang, Mengfan
|
|
|
298 |
6 |
p.
|
artikel
|
| 46 |
αα-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes
|
Friis Theisen, Frederik
|
|
|
298 |
6 |
p.
|
artikel
|
| 47 |
Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer’s disease
|
Gonzalez-Gil, Anabel
|
|
|
298 |
6 |
p.
|
artikel
|
| 48 |
Human C1orf27 protein interacts with α2A-adrenergic receptor and regulates its anterograde transport
|
Xu, Xin
|
|
|
298 |
6 |
p.
|
artikel
|
| 49 |
Human UFSP1 translated from an upstream near-cognate initiation codon functions as an active UFM1-specific protease
|
Liang, Qian
|
|
|
298 |
6 |
p.
|
artikel
|
| 50 |
Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase
|
Tabassum, Zarin
|
|
|
298 |
6 |
p.
|
artikel
|
| 51 |
Identification of distinct N-glycosylation patterns on extracellular vesicles from small-cell and non–small-cell lung cancer cells
|
Kondo, Kiyotaka
|
|
|
298 |
6 |
p.
|
artikel
|
| 52 |
Intersubunit and intrasubunit interactions driving the MukBEF ATPase
|
Bahng, Soon
|
|
|
298 |
6 |
p.
|
artikel
|
| 53 |
In vivo regulation of bacterial Rho-dependent transcription termination by the nascent RNA
|
Chhakchhuak, Passong Immanual R.
|
|
|
298 |
6 |
p.
|
artikel
|
| 54 |
Iron accumulation with age alters metabolic pattern and circadian clock gene expression through the reduction of AMP-modulated histone methylation
|
Liu, Junhao
|
|
|
298 |
6 |
p.
|
artikel
|
| 55 |
Key dimer interface residues impact the catalytic activity of 3CLpro, the main protease of SARS-CoV-2
|
Ferreira, Juliana C.
|
|
|
298 |
6 |
p.
|
artikel
|
| 56 |
KLIF-associated cytoskeletal proteins in Trypanosoma brucei regulate cytokinesis by promoting cleavage furrow positioning and ingression
|
Zhou, Qing
|
|
|
298 |
6 |
p.
|
artikel
|
| 57 |
Leukemia inhibitory factor protects against liver steatosis in nonalcoholic fatty liver disease patients and obese mice
|
Yuan, Youwen
|
|
|
298 |
6 |
p.
|
artikel
|
| 58 |
Loss of mitochondrial ATPase ATAD3A contributes to nonalcoholic fatty liver disease through accumulation of lipids and damaged mitochondria
|
Chen, Liting
|
|
|
298 |
6 |
p.
|
artikel
|
| 59 |
Lysophosphatidylcholine acyltransferase 1 controls mitochondrial reactive oxygen species generation and survival of retinal photoreceptor cells
|
Nagata, Katsuyuki
|
|
|
298 |
6 |
p.
|
artikel
|
| 60 |
Mechanistic insights into the activation of the IKK kinase complex by the Kaposi’s sarcoma herpes virus oncoprotein vFLIP
|
Bagnéris, Claire
|
|
|
298 |
6 |
p.
|
artikel
|
| 61 |
microRNA-27b regulates hepatic lipase enzyme LIPC and reduces triglyceride degradation during hepatitis C virus infection
|
Desrochers, Geneviève.F.
|
|
|
298 |
6 |
p.
|
artikel
|
| 62 |
MicroRNA-200c coordinates HNF1 homeobox B and apolipoprotein O functions to modulate lipid homeostasis in alcoholic fatty liver disease
|
Mostofa, Md Golam
|
|
|
298 |
6 |
p.
|
artikel
|
| 63 |
Molecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules
|
Zhang, Nannan
|
|
|
298 |
6 |
p.
|
artikel
|
| 64 |
MRAP2 inhibits β-arrestin recruitment to the ghrelin receptor by preventing GHSR1a phosphorylation
|
Rouault, Alix A.J.
|
|
|
298 |
6 |
p.
|
artikel
|
| 65 |
mRNA and tRNA modification states influence ribosome speed and frame maintenance during poly(lysine) peptide synthesis
|
Smith, Tyler J.
|
|
|
298 |
6 |
p.
|
artikel
|
| 66 |
mTORC1 regulates high levels of protein synthesis in retinal ganglion cells of adult mice
|
Fort, Patrice E.
|
|
|
298 |
6 |
p.
|
artikel
|
| 67 |
Nej1 interacts with Sae2 at DNA double-stranded breaks to inhibit DNA resection
|
Mojumdar, Aditya
|
|
|
298 |
6 |
p.
|
artikel
|
| 68 |
Novel salivary antihemostatic activities of long-form D7 proteins from the malaria vector Anopheles gambiae facilitate hematophagy
|
Smith, Leticia Barion
|
|
|
298 |
6 |
p.
|
artikel
|
| 69 |
Nuclear focal adhesion kinase induces APC/C activator protein CDH1-mediated cyclin-dependent kinase 4/6 degradation and inhibits melanoma proliferation
|
Murphy, James M.
|
|
|
298 |
6 |
p.
|
artikel
|
| 70 |
O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond
|
Berardinelli, Steven J.
|
|
|
298 |
6 |
p.
|
artikel
|
| 71 |
Oxidized high-density lipoprotein promotes CD36 palmitoylation and increases lipid uptake in macrophages
|
Zhang, Yun
|
|
|
298 |
6 |
p.
|
artikel
|
| 72 |
Palmitoylation of the small GTPase Cdc42 by DHHC5 modulates spine formation and gene transcription
|
Wirth, Alexander
|
|
|
298 |
6 |
p.
|
artikel
|
| 73 |
Phosphorylation at Ser724 of the ER stress sensor IRE1α governs its activation state and limits ER stress–induced hepatosteatosis
|
Li, Yang
|
|
|
298 |
6 |
p.
|
artikel
|
| 74 |
PKC regulation of ion channels: The involvement of PIP2
|
Gada, Kirin D.
|
|
|
298 |
6 |
p.
|
artikel
|
| 75 |
Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression
|
Beauvais, DeannaLee M.
|
|
|
298 |
6 |
p.
|
artikel
|
| 76 |
Positively charged amino acids at the N terminus of select mitochondrial proteins mediate early recognition by import proteins αβ′-NAC and Sam37
|
Avendaño-Monsalve, Maria Clara
|
|
|
298 |
6 |
p.
|
artikel
|
| 77 |
Posttranslational regulation of mitochondrial frataxin and identification of compounds that increase frataxin levels in Friedreich’s ataxia
|
Hackett, Peter T.
|
|
|
298 |
6 |
p.
|
artikel
|
| 78 |
Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways
|
Delgado, Magdalena
|
|
|
298 |
6 |
p.
|
artikel
|
| 79 |
Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1
|
Buel, Gwen R.
|
|
|
298 |
6 |
p.
|
artikel
|
| 80 |
Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling
|
Agajanian, Megan J.
|
|
|
298 |
6 |
p.
|
artikel
|
| 81 |
Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease
|
Serganov, Artem A.
|
|
|
298 |
6 |
p.
|
artikel
|
| 82 |
Regulator of G protein signaling 2 inhibits Gαq-dependent uveal melanoma cell growth
|
Zhang, Qian
|
|
|
298 |
6 |
p.
|
artikel
|
| 83 |
Residues located in the primase domain of the bacteriophage T7 primase-helicase are essential for loading the hexameric complex onto DNA
|
Hernandez, Alfredo J.
|
|
|
298 |
6 |
p.
|
artikel
|
| 84 |
Resurrection of an ancient inflammatory locus reveals switch to caspase-1 specificity on a caspase-4 scaffold
|
Bibo-Verdugo, Betsaida
|
|
|
298 |
6 |
p.
|
artikel
|
| 85 |
SGK1 negatively regulates inflammatory immune responses and protects against alveolar bone loss through modulation of TRAF3 activity
|
Han, Xiao
|
|
|
298 |
6 |
p.
|
artikel
|
| 86 |
Stable G-quadruplex DNA structures promote replication-dependent genome instability
|
Rider Jr., S. Dean
|
|
|
298 |
6 |
p.
|
artikel
|
| 87 |
Sticking to starch
|
Brumer, Harry
|
|
|
298 |
6 |
p.
|
artikel
|
| 88 |
Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants
|
Greasley, Samantha E.
|
|
|
298 |
6 |
p.
|
artikel
|
| 89 |
Structure and role of the linker domain of the iron surface-determinant protein IsdH in heme transportation in Staphylococcus aureus
|
Valenciano-Bellido, Sandra
|
|
|
298 |
6 |
p.
|
artikel
|
| 90 |
Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m1A22-tRNA methyltransferase TrmK
|
Sweeney, Pamela
|
|
|
298 |
6 |
p.
|
artikel
|
| 91 |
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation
|
Nagy, Zoltán Attila
|
|
|
298 |
6 |
p.
|
artikel
|
| 92 |
The activity of the serotonergic 5-HT1A receptor is modulated by voltage and sodium levels
|
Tauber, Merav
|
|
|
298 |
6 |
p.
|
artikel
|
| 93 |
The bacterial yjdF riboswitch regulates translation through its tRNA-like fold
|
Trachman III, Robert J.
|
|
|
298 |
6 |
p.
|
artikel
|
| 94 |
The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection
|
Schor, Stanford
|
|
|
298 |
6 |
p.
|
artikel
|
| 95 |
The central inflammasome adaptor protein ASC activates the inflammasome after transition from a soluble to an insoluble state
|
Prather, Evan R.
|
|
|
298 |
6 |
p.
|
artikel
|
| 96 |
The cryo-EM structure of the S-layer deinoxanthin-binding complex of Deinococcus radiodurans informs properties of its environmental interactions
|
Farci, Domenica
|
|
|
298 |
6 |
p.
|
artikel
|
| 97 |
The dual fates of exogenous tau seeds: Lysosomal clearance versus cytoplasmic amplification
|
Kolay, Sourav
|
|
|
298 |
6 |
p.
|
artikel
|
| 98 |
The early molecular events leading to COFILIN phosphorylation during mouse sperm capacitation are essential for acrosomal exocytosis
|
Schiavi-Ehrenhaus, Liza J.
|
|
|
298 |
6 |
p.
|
artikel
|
| 99 |
The JMJD3 histone demethylase inhibitor GSK-J1 ameliorates lipopolysaccharide-induced inflammation in a mastitis model
|
Wang, Jing-Jing
|
|
|
298 |
6 |
p.
|
artikel
|
| 100 |
The long β2,3-sheets encoded by redundant sequences play an integral role in the channel function of P2X7 receptors
|
Ma, Xue-Fei
|
|
|
298 |
6 |
p.
|
artikel
|
| 101 |
The mammalian rhomboid protein RHBDL4 protects against endoplasmic reticulum stress by regulating the morphology and distribution of ER sheets
|
Lastun, Viorica L.
|
|
|
298 |
6 |
p.
|
artikel
|
| 102 |
The metalloprotease ADAM10 generates soluble interleukin-2 receptor alpha (sCD25) in v ivo
|
Kirschke, Sophia
|
|
|
298 |
6 |
p.
|
artikel
|
| 103 |
The reductive half-reaction of two bifurcating electron-transferring flavoproteins
|
Vigil Jr., Wayne
|
|
|
298 |
6 |
p.
|
artikel
|
| 104 |
The transmembrane domain of the amyloid precursor protein is required for antiamyloidogenic processing by α-secretase ADAM10
|
Hitschler, Lisa
|
|
|
298 |
6 |
p.
|
artikel
|
| 105 |
Transcription factors KLF15 and PPARδ cooperatively orchestrate genome-wide regulation of lipid metabolism in skeletal muscle
|
Fan, Liyan
|
|
|
298 |
6 |
p.
|
artikel
|
| 106 |
Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel’s γ-subunit
|
Sure, Florian
|
|
|
298 |
6 |
p.
|
artikel
|
| 107 |
Ubiquitin-conjugating activity by PEX4 is required for efficient protein transport to peroxisomes in Arabidopsis thaliana
|
Mano, Shoji
|
|
|
298 |
6 |
p.
|
artikel
|
| 108 |
Ubiquitin-directed AAA+ ATPase p97/VCP unfolds stable proteins crosslinked to DNA for proteolysis by SPRTN
|
Kröning, Alexander
|
|
|
298 |
6 |
p.
|
artikel
|
| 109 |
Withdrawal: Ceramide stabilizes β-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid β-peptide biogenesis
|
Puglielli, Luigi
|
|
|
298 |
6 |
p.
|
artikel
|
| 110 |
Yeast cells depleted of the frataxin homolog Yfh1 redistribute cellular iron: Studies using Mössbauer spectroscopy and mathematical modeling
|
Fernandez, Salvador
|
|
|
298 |
6 |
p.
|
artikel
|
| 111 |
Zinc transport via ZNT5-6 and ZNT7 is critical for cell surface glycosylphosphatidylinositol-anchored protein expression
|
Wagatsuma, Takumi
|
|
|
298 |
6 |
p.
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artikel
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