| nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
| 1 |
A catalytic dyad modulates conformational change in the CO2-fixing flavoenzyme 2-ketopropyl coenzyme M oxidoreductase/carboxylase
|
Mattice, Jenna R.
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298 |
5 |
p.
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artikel
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| 2 |
Accessibility of ENaC extracellular domain central core residues
|
Zhang, Lei
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298 |
5 |
p.
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artikel
|
| 3 |
A computational model of cardiomyocyte metabolism predicts unique reperfusion protocols capable of reducing cell damage during ischemia/reperfusion
|
Grass, Matthias
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298 |
5 |
p.
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artikel
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| 4 |
A genetically targeted sensor reveals spatial and temporal dynamics of acrosomal calcium and sperm acrosome exocytosis
|
Cohen, Roy
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298 |
5 |
p.
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artikel
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| 5 |
A kinetic model of phospholipase C-γ1 linking structure-based insights to dynamics of enzyme autoinhibition and activation
|
Nosbisch, Jamie L.
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298 |
5 |
p.
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artikel
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| 6 |
Allosteric regulation by membranes and hydrophobic subsites in phospholipase A2 enzymes determine their substrate specificity
|
Dennis, Edward A.
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298 |
5 |
p.
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artikel
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| 7 |
Ammonia induces amyloidogenesis in astrocytes by promoting amyloid precursor protein translocation into the endoplasmic reticulum
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Komatsu, Ayaka
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298 |
5 |
p.
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artikel
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| 8 |
A new technique for genome-wide mapping of nucleotide excision repair without immunopurification of damaged DNA
|
Wu, Sizhong
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298 |
5 |
p.
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artikel
|
| 9 |
An miRNA derived from amelogenin exon4 regulates expression of transcription factor Runx2 by directly targeting upstream activators Nfia and Prkch
|
Shemirani, Rozana
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298 |
5 |
p.
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artikel
|
| 10 |
An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins
|
Gada, Kirin D.
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298 |
5 |
p.
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artikel
|
| 11 |
Antigen binding by conformational selection in near-germline antibodies
|
Blackler, Ryan J.
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298 |
5 |
p.
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artikel
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| 12 |
A primer to traction force microscopy
|
Zancla, Andrea
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298 |
5 |
p.
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artikel
|
| 13 |
A single phenylalanine residue in β-arrestin2 critically regulates its binding to G protein–coupled receptors
|
Jean-Charles, Pierre-Yves
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298 |
5 |
p.
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artikel
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| 14 |
Biochemical purification uncovers mammalian sterile 3 (MST3) as a new protein kinase for multifunctional protein kinases AMPK and SIK3
|
Liu, Yuxiang
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298 |
5 |
p.
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artikel
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| 15 |
Bioinformatic identification of previously unrecognized amyloidogenic proteins
|
Rosenberg, Gregory M.
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298 |
5 |
p.
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artikel
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| 16 |
Calmodulin activates the Hippo signaling pathway by promoting LATS1 kinase–mediated inhibitory phosphorylation of the transcriptional coactivator YAP
|
Thines, Louise
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|
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298 |
5 |
p.
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artikel
|
| 17 |
Capsaicin inhibits intestinal Cl- secretion and promotes Na+ absorption by blocking TRPV4 channels in healthy and colitic mice
|
Wan, Hanxing
|
|
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298 |
5 |
p.
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artikel
|
| 18 |
Carbamazepine promotes surface expression of mutant Kir6.2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy
|
Lin, Ching-Han
|
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|
298 |
5 |
p.
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artikel
|
| 19 |
Cathepsin D interacts with adenosine A2A receptors in mouse macrophages to modulate cell surface localization and inflammatory signaling
|
Skopál, Adrienn
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298 |
5 |
p.
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artikel
|
| 20 |
Characterization of a phylogenetically distinct extradiol dioxygenase involved in the bacterial catabolism of lignin-derived aromatic compounds
|
Navas, Laura E.
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298 |
5 |
p.
|
artikel
|
| 21 |
Characterization of interactions within the Igα/Igβ transmembrane domains of the human B-cell receptor provides insights into receptor assembly
|
Lockey, Christine
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|
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298 |
5 |
p.
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artikel
|
| 22 |
Correction: High cell surface death receptor expression determines type I versus type II signaling
|
Meng, Xue Wei
|
|
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298 |
5 |
p.
|
artikel
|
| 23 |
Cover
|
|
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298 |
5 |
p.
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artikel
|
| 24 |
CPR-C4 is a highly conserved novel protease from the Candidate Phyla Radiation with remote structural homology to human vasohibins
|
Cornish, Katy A.S.
|
|
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298 |
5 |
p.
|
artikel
|
| 25 |
Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel
|
Ren, Yue
|
|
|
298 |
5 |
p.
|
artikel
|
| 26 |
Crystal structures of pertussis toxin with NAD+ and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity
|
Sakari, Moona
|
|
|
298 |
5 |
p.
|
artikel
|
| 27 |
Deciphering functional redundancy and energetics of malate oxidation in mycobacteria
|
Harold, Liam K.
|
|
|
298 |
5 |
p.
|
artikel
|
| 28 |
Degron-mediated proteolysis of CrhR-like DEAD-box RNA helicases in cyanobacteria
|
Whitman, Brendan T.
|
|
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298 |
5 |
p.
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artikel
|
| 29 |
Degron tagging of BleoR and other antibiotic-resistance genes selects for higher expression of linked transgenes and improved exosome engineering
|
Tsai, Shang Jui
|
|
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298 |
5 |
p.
|
artikel
|
| 30 |
Design, synthesis, and biological evaluation of a small molecule oral agonist of the glucagon-like-peptide-1 receptor
|
Girdhar, Khyati
|
|
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298 |
5 |
p.
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artikel
|
| 31 |
DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap1
|
Ma, Xiaolu
|
|
|
298 |
5 |
p.
|
artikel
|
| 32 |
Downregulation of the endothelial histone demethylase JMJD3 is associated with neointimal hyperplasia of arteriovenous fistulas in kidney failure
|
Feng, Shaozhen
|
|
|
298 |
5 |
p.
|
artikel
|
| 33 |
Entecavir competitively inhibits deoxyguanosine and deoxyadenosine phosphorylation in isolated mitochondria and the perfused rat heart
|
Ward, Avery S.
|
|
|
298 |
5 |
p.
|
artikel
|
| 34 |
Enzymatic analysis of WWP2 E3 ubiquitin ligase using protein microarrays identifies autophagy-related substrates
|
Jiang, Hanjie
|
|
|
298 |
5 |
p.
|
artikel
|
| 35 |
Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase–pyrophosphatases that act via a covalent aspartyl–phosphate intermediate
|
Sanchez, Ana M.
|
|
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298 |
5 |
p.
|
artikel
|
| 36 |
Fluorescence lifetime imaging microscopy reveals sodium pump dimers in live cells
|
Seflova, Jaroslava
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|
|
298 |
5 |
p.
|
artikel
|
| 37 |
Folding or holding?—Hsp70 and Hsp90 chaperoning of misfolded proteins in neurodegenerative disease
|
Rutledge, Benjamin S.
|
|
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298 |
5 |
p.
|
artikel
|
| 38 |
Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties
|
Kim, Seon Beom
|
|
|
298 |
5 |
p.
|
artikel
|
| 39 |
FSH mediates estradiol synthesis in hypoxic granulosa cells by activating glycolytic metabolism through the HIF-1α–AMPK–GLUT1 signaling pathway
|
Wu, Gang
|
|
|
298 |
5 |
p.
|
artikel
|
| 40 |
Functional inhibition of c-Myc using novel inhibitors identified through “hot spot” targeting
|
Singh, Ashutosh
|
|
|
298 |
5 |
p.
|
artikel
|
| 41 |
Gasdermin E is required for induction of pyroptosis and severe disease during enterovirus 71 infection
|
Dong, Siwen
|
|
|
298 |
5 |
p.
|
artikel
|
| 42 |
Glycation modulates alpha-synuclein fibrillization kinetics: A sweet spot for inhibition
|
Farzadfard, Azad
|
|
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298 |
5 |
p.
|
artikel
|
| 43 |
Gonadal white adipose tissue is important for gametogenesis in mice through maintenance of local metabolic and immune niches
|
Yang, Chao-Fan
|
|
|
298 |
5 |
p.
|
artikel
|
| 44 |
Human constitutive androstane receptor represses liver cancer development and hepatoma cell proliferation by inhibiting erythropoietin signaling
|
Li, Zhihui
|
|
|
298 |
5 |
p.
|
artikel
|
| 45 |
Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea
|
Goldsmith, Moshe
|
|
|
298 |
5 |
p.
|
artikel
|
| 46 |
Identification and characterization of two novel noncoding tyrosinase (TYR) gene variants leading to oculocutaneous albinism type 1
|
Li, Chaoyi
|
|
|
298 |
5 |
p.
|
artikel
|
| 47 |
Identification of a poly-cyclopropylglycine–containing peptide via bioinformatic mapping of radical S-adenosylmethionine enzymes
|
Kostenko, Anastasiia
|
|
|
298 |
5 |
p.
|
artikel
|
| 48 |
In situ artificial contact sites (ISACS) between synthetic and endogenous organelle membranes allow for quantification of protein-tethering activities
|
Milanini, Julie
|
|
|
298 |
5 |
p.
|
artikel
|
| 49 |
In vivo growth of Staphylococcus lugdunensis is facilitated by the concerted function of heme and non-heme iron acquisition mechanisms
|
Flannagan, Ronald S.
|
|
|
298 |
5 |
p.
|
artikel
|
| 50 |
Long noncoding RNA ELDR promotes cell cycle progression in normal oral keratinocytes through induction of a CTCF-FOXM1-AURKA signaling axis
|
Sur, Subhayan
|
|
|
298 |
5 |
p.
|
artikel
|
| 51 |
Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation
|
Collins, Galen Andrew
|
|
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298 |
5 |
p.
|
artikel
|
| 52 |
Mechanism of proteasome gate modulation by assembly chaperones Pba1 and Pba2
|
Schnell, Helena M.
|
|
|
298 |
5 |
p.
|
artikel
|
| 53 |
Mechanisms tailoring the expression of heat shock proteins to proteostasis challenges
|
Alagar Boopathy, Lokha R.
|
|
|
298 |
5 |
p.
|
artikel
|
| 54 |
Metabolic changes accompanying the loss of fumarate hydratase and malate–quinone oxidoreductase in the asexual blood stage of Plasmodium falciparum
|
Rajaram, Krithika
|
|
|
298 |
5 |
p.
|
artikel
|
| 55 |
Mitochondria-associated myosin 19 processively transports mitochondria on actin tracks in living cells
|
Sato, Osamu
|
|
|
298 |
5 |
p.
|
artikel
|
| 56 |
Mitochondrial ATP synthase inhibitory factor 1 interacts with the p53–cyclophilin D complex and promotes opening of the permeability transition pore
|
Guo, Lishu
|
|
|
298 |
5 |
p.
|
artikel
|
| 57 |
Mitochondrial protein translocation machinery: From TOM structural biogenesis to functional regulation
|
Sayyed, Ulfat Mohd. Hanif
|
|
|
298 |
5 |
p.
|
artikel
|
| 58 |
Mitogen-activated protein kinase phosphatase-1 controls PD-L1 expression by regulating type I interferon during systemic Escherichia coli infection
|
Barley, Timothy J.
|
|
|
298 |
5 |
p.
|
artikel
|
| 59 |
Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis
|
Roig-Zamboni, Véronique
|
|
|
298 |
5 |
p.
|
artikel
|
| 60 |
Monitoring the induction of ferroptosis following dissociation in human embryonic stem cells
|
Babaei-Abraki, Shahnaz
|
|
|
298 |
5 |
p.
|
artikel
|
| 61 |
Multienzyme interactions of the de novo purine biosynthetic protein PAICS facilitate purinosome formation and metabolic channeling
|
He, Jingxuan
|
|
|
298 |
5 |
p.
|
artikel
|
| 62 |
Mycobacterium tuberculosis encodes a YhhN family membrane protein with lysoplasmalogenase activity that protects against toxic host lysolipids
|
Jurkowitz, Marianne S.
|
|
|
298 |
5 |
p.
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artikel
|
| 63 |
Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site
|
Sanders, Matthew J.
|
|
|
298 |
5 |
p.
|
artikel
|
| 64 |
Next-generation sequencing: A new avenue to understand viral RNA–protein interactions
|
Zhou, Yiyang
|
|
|
298 |
5 |
p.
|
artikel
|
| 65 |
Paip2A inhibits translation by competitively binding to the RNA recognition motifs of PABPC1 and promoting its dissociation from the poly(A) tail
|
Sagae, Takeru
|
|
|
298 |
5 |
p.
|
artikel
|
| 66 |
PALMD regulates aortic valve calcification via altered glycolysis and NF-κB–mediated inflammation
|
Wang, Siying
|
|
|
298 |
5 |
p.
|
artikel
|
| 67 |
Periosteum-derived podoplanin-expressing stromal cells regulate nascent vascularization during epiphyseal marrow development
|
Tamura, Shogo
|
|
|
298 |
5 |
p.
|
artikel
|
| 68 |
Protein folding stabilities are a major determinant of oxidation rates for buried methionine residues
|
Walker, Ethan J.
|
|
|
298 |
5 |
p.
|
artikel
|
| 69 |
Protein phosphatase 2A regulates cytotoxicity and drug resistance by dephosphorylating AHR and MDR1
|
Chen, Liping
|
|
|
298 |
5 |
p.
|
artikel
|
| 70 |
Purine biosynthetic enzymes assemble into liquid-like condensates dependent on the activity of chaperone protein HSP90
|
Pedley, Anthony M.
|
|
|
298 |
5 |
p.
|
artikel
|
| 71 |
Recent structural insights into the mechanism of ClpP protease regulation by AAA+ chaperones and small molecules
|
Mabanglo, Mark F.
|
|
|
298 |
5 |
p.
|
artikel
|
| 72 |
Regulatory subunit NEMO promotes polyubiquitin-dependent induction of NF-κB through a targetable second interaction with upstream activator IKK2
|
Ko, Myung Soo
|
|
|
298 |
5 |
p.
|
artikel
|
| 73 |
Replication of the coronavirus genome: A paradox among positive-strand RNA viruses
|
Grellet, Emeline
|
|
|
298 |
5 |
p.
|
artikel
|
| 74 |
RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein
|
Friedman, Peter A.
|
|
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298 |
5 |
p.
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artikel
|
| 75 |
Ribosomal protein S18 acetyltransferase RimI is responsible for the acetylation of elongation factor Tu
|
Pletnev, Philipp I.
|
|
|
298 |
5 |
p.
|
artikel
|
| 76 |
RNA polymerase I (Pol I) lobe-binding subunit Rpa12.2 promotes RNA cleavage and proofreading
|
Schwank, Katrin
|
|
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298 |
5 |
p.
|
artikel
|
| 77 |
Sas20 is a highly flexible starch-binding protein in the Ruminococcus bromii cell-surface amylosome
|
Cerqueira, Filipe M.
|
|
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298 |
5 |
p.
|
artikel
|
| 78 |
Selective phosphorylation of threonine residues defines GPR84–arrestin interactions of biased ligands
|
Marsango, Sara
|
|
|
298 |
5 |
p.
|
artikel
|
| 79 |
Sialoglycan-binding patterns of bacterial AB5 toxin B subunits correlate with host range and toxicity, indicating evolution independent of A subunits
|
Khan, Naazneen
|
|
|
298 |
5 |
p.
|
artikel
|
| 80 |
Solution structure ensemble of human obesity-associated protein FTO reveals druggable surface pockets at the interface between the N- and C-terminal domain
|
Khatiwada, Balabhadra
|
|
|
298 |
5 |
p.
|
artikel
|
| 81 |
Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
|
Cross, Alice R.
|
|
|
298 |
5 |
p.
|
artikel
|
| 82 |
Spirocyclic dimer SpiD7 activates the unfolded protein response to selectively inhibit growth and induce apoptosis of cancer cells
|
Kour, Smit
|
|
|
298 |
5 |
p.
|
artikel
|
| 83 |
STE20 phosphorylation of AMPK-related kinases revealed by biochemical purifications combined with genetics
|
Liu, Yuxiang
|
|
|
298 |
5 |
p.
|
artikel
|
| 84 |
Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing
|
Chen, Qiujia
|
|
|
298 |
5 |
p.
|
artikel
|
| 85 |
Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity
|
Detry, Sam
|
|
|
298 |
5 |
p.
|
artikel
|
| 86 |
Structural basis of the strict specificity of a bacterial GH31 α-1,3-glucosidase for nigerooligosaccharides
|
Ikegaya, Marina
|
|
|
298 |
5 |
p.
|
artikel
|
| 87 |
Structural characterization of the homotropic cooperative binding of azamulin to human cytochrome P450 3A5
|
Hsu, Mei-Hui
|
|
|
298 |
5 |
p.
|
artikel
|
| 88 |
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
|
Shon, D. Judy
|
|
|
298 |
5 |
p.
|
artikel
|
| 89 |
Substrate-binding loop interactions with pseudouridine trigger conformational changes that promote catalytic efficiency of pseudouridine kinase PUKI
|
Kim, Sang-Hoon
|
|
|
298 |
5 |
p.
|
artikel
|
| 90 |
The CLIP-170 N-terminal domain binds directly to both F-actin and microtubules in a mutually exclusive manner
|
Wu, Yueh-Fu O.
|
|
|
298 |
5 |
p.
|
artikel
|
| 91 |
The dimerization mechanism of the N-terminal domain of spider silk proteins is conserved despite extensive sequence divergence
|
Sarr, Médoune
|
|
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298 |
5 |
p.
|
artikel
|
| 92 |
The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP
|
Umano, A.
|
|
|
298 |
5 |
p.
|
artikel
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| 93 |
The mouse nicotinamide mononucleotide adenylyltransferase chaperones diverse pathological amyloid client proteins
|
Huang, Chengan
|
|
|
298 |
5 |
p.
|
artikel
|
| 94 |
The N-terminal domain of the Agrobacterium tumefaciens telomere resolvase, TelA, regulates its DNA cleavage and rejoining activities
|
McGrath, Siobhan L.
|
|
|
298 |
5 |
p.
|
artikel
|
| 95 |
The role of cellular proteostasis in antitumor immunity
|
Mercier, Rebecca
|
|
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298 |
5 |
p.
|
artikel
|
| 96 |
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains
|
Peña-Díaz, Samuel
|
|
|
298 |
5 |
p.
|
artikel
|
| 97 |
The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs
|
Liu, Liping
|
|
|
298 |
5 |
p.
|
artikel
|
| 98 |
Transcriptional coactivator PGC-1α contributes to decidualization by forming a histone-modifying complex with C/EBPβ and p300
|
Takagi, Haruka
|
|
|
298 |
5 |
p.
|
artikel
|
| 99 |
Trophic factor BDNF inhibits GABAergic signaling by facilitating dendritic enrichment of SUMO E3 ligase PIAS3 and altering gephyrin scaffold
|
Thirouin, Zahra S.
|
|
|
298 |
5 |
p.
|
artikel
|
| 100 |
Understanding the physical basis of memory: Molecular mechanisms of the engram
|
Ortega-de San Luis, Clara
|
|
|
298 |
5 |
p.
|
artikel
|
| 101 |
Unique properties of a Dictyostelium discoideum carbohydrate-binding module expand our understanding of CBM–ligand interactions
|
Liberato, Marcelo Vizona
|
|
|
298 |
5 |
p.
|
artikel
|
| 102 |
Withdrawal: Novel role for p21-activated kinase 2 in thrombin-induced monocyte migration
|
Gadepalli, Ravisekhar
|
|
|
298 |
5 |
p.
|
artikel
|
| 103 |
You cannot oxidize what you cannot reach: Oxidative susceptibility of buried methionine residues
|
Kulczyk, Arkadiusz W.
|
|
|
298 |
5 |
p.
|
artikel
|
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