Digitale Bibliotheek
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                             141 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A copper chaperone–mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis McAlary, L.

298 3 p.
artikel
2 ADAR1- and ADAR2-mediated regulation of maturation and targeting of miR-376b to modulate GABA neurotransmitter catabolism Widmark, Albin

298 3 p.
artikel
3 AdipoRon exerts opposing effects on insulin sensitivity via fibroblast growth factor 21–mediated time-dependent mechanisms Wang, Yongliang

298 3 p.
artikel
4 Agonist-induced phosphorylation of orthologues of the orphan receptor GPR35 functions as an activation sensor Divorty, Nina

298 3 p.
artikel
5 A hydrophilic microenvironment in the substrate-translocating groove of the YidC membrane insertase is essential for enzyme function Chen, Yuanyuan

298 3 p.
artikel
6 A lysine-rich cluster in the N-BAR domain of ARF GTPase-activating protein ASAP1 is necessary for binding and bundling actin filaments Gasilina, Anjelika

298 3 p.
artikel
7 A mouse model of inherited choline kinase β-deficiency presents with specific cardiac abnormalities and a predisposition to arrhythmia Tavasoli, Mahtab

298 3 p.
artikel
8 Antibodies binding diverse pertactin epitopes protect mice from Bordetella pertussis infection Silva, Rui P.

298 3 p.
artikel
9 A pGpG-specific phosphodiesterase regulates cyclic di-GMP signaling in Vibrio cholerae Heo, Kyoo

298 3 p.
artikel
10 Assembly and architecture of Escherichia coli divisome proteins FtsA and FtsZ Morrison, Josiah J.

298 3 p.
artikel
11 Can two wrongs make a right? F508del-CFTR ion channel rescue by second-site mutations in its transmembrane domains Prins, Stella

298 3 p.
artikel
12 Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation Minogue, Peter J.

298 3 p.
artikel
13 Cellular prion protein in human plasma–derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor–LRP1 receptor system Gonias, Steven L.

298 3 p.
artikel
14 Characterization and structural analyses of a novel glycosyltransferase acting on the β-1,2-glucosidic linkages Kobayashi, Kaito

298 3 p.
artikel
15 Chronic exposure to the anti-M3 muscarinic acetylcholine receptor autoantibody in pemphigus vulgaris contributes to disease pathophysiology Chernyavsky, Alex

298 3 p.
artikel
16 Comparison of glycoside hydrolase family 3 β-xylosidases from basidiomycetes and ascomycetes reveals evolutionarily distinct xylan degradation systems Kojima, Keisuke

298 3 p.
artikel
17 Competitively disrupting the neutrophil-specific receptor–autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation Marino, Stephen F.

298 3 p.
artikel
18 Complexities of complex II: Sulfide metabolism in vivo Cecchini, Gary

298 3 p.
artikel
19 Copper(II) import and reduction are dependent on His-Met clusters in the extracellular amino terminus of human copper transporter-1 Kar, Sumanta

298 3 p.
artikel
20 Correction: Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel Burton, Mark J.

298 3 p.
artikel
21 Correction: Structure, function, and substrates of Clp AAA+ protease systems in cyanobacteria, plastids, and apicoplasts: A comparative analysis Bouchnak, Imen

298 3 p.
artikel
22 Cover
298 3 p.
artikel
23 Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I Grba, Daniel N.

298 3 p.
artikel
24 Cryo-EM structure of hexameric yeast Lon protease (PIM1) highlights the importance of conserved structural elements Yang, Jie

298 3 p.
artikel
25 Deciphering the evolution of metallo-β-lactamases: A journey from the test tube to the bacterial periplasm López, Carolina

298 3 p.
artikel
26 Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G Byun, Jung Ah

298 3 p.
artikel
27 Dual-functional significance of ATM-mediated phosphorylation of spindle assembly checkpoint component Bub3 in mitosis and the DNA damage response Xiao, Mingming

298 3 p.
artikel
28 eIF3k inhibits NF-κB signaling by targeting MyD88 for ATG5-mediated autophagic degradation in teleost fish Chen, Ya

298 3 p.
artikel
29 Elimination of Aicardi–Goutières syndrome protein SAMHD1 activates cellular innate immunity and suppresses SARS-CoV-2 replication Oo, Adrian

298 3 p.
artikel
30 Endosomal TLR3 signaling in stromal osteoblasts induces prostaglandin E2–mediated inflammatory periodontal bone resorption Tominari, Tsukasa

298 3 p.
artikel
31 Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10 Raeeszadeh-Sarmazdeh, Maryam

298 3 p.
artikel
32 Enhanced immunoprecipitation techniques for the identification of RNA-binding protein partners: IGF2BP1 interactions in mammary epithelial cells Fakhraldeen, Saja A.

298 3 p.
artikel
33 Escherichia coli alanyl-tRNA synthetase maintains proofreading activity and translational accuracy under oxidative stress Kavoor, Arundhati

298 3 p.
artikel
34 Exosomal miR-673-5p from fibroblasts promotes Schwann cell-mediated peripheral neuron myelination by targeting the TSC2/mTORC1/SREBP2 axis Zhao, Yahong

298 3 p.
artikel
35 Expanded substrate specificity supported by P1′ and P2′ residues enables bacterial dipeptidyl-peptidase 7 to degrade bioactive peptides Ohara-Nemoto, Yuko

298 3 p.
artikel
36 Expanding polysaccharide–protein coupling of glycoconjugate vaccines Berti, Francesco

298 3 p.
artikel
37 Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle Walklate, Jonathan

298 3 p.
artikel
38 Expression of gamma-glutamyltransferase 1 in glioblastoma cells confers resistance to cystine deprivation–induced ferroptosis Hayashima, Kazuki

298 3 p.
artikel
39 Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation Medeiros, Philip J.

298 3 p.
artikel
40 FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury Lee, Bohm

298 3 p.
artikel
41 Flavivirus recruits the valosin-containing protein–NPL4 complex to induce stress granule disassembly for efficient viral genome replication Arakawa, Masashi

298 3 p.
artikel
42 Fluorescent sensors of siderophores produced by bacterial pathogens Kumar, Ashish

298 3 p.
artikel
43 FNDC5/irisin facilitates muscle−adipose−bone connectivity through ubiquitination-dependent activation of runt-related transcriptional factors RUNX1/2 He, Xinyu

298 3 p.
artikel
44 Functionally additive fixed positive and negative charges in the CFTR channel pore control anion binding and conductance Linsdell, Paul

298 3 p.
artikel
45 HBXIP is a novel regulator of the unfolded protein response that sustains tamoxifen resistance in ER+ breast cancer Zhang, Shenghong

298 3 p.
artikel
46 High-affinity TrkA and p75 neurotrophin receptor complexes: A twisted affair Conroy, Jacinta N.

298 3 p.
artikel
47 Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes Gullett, Jessica M.

298 3 p.
artikel
48 Immunosuppressive calcineurin inhibitor cyclosporine A induces proapoptotic endoplasmic reticulum stress in renal tubular cells Yilmaz, Duygu Elif

298 3 p.
artikel
49 Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation Byts, Nadiya

298 3 p.
artikel
50 Inflammasome regulation by adaptor isoforms, ASC and ASCb, via differential self-assembly Diaz-Parga, Pedro

298 3 p.
artikel
51 Inhibition of mitochondrial LonP1 protease by allosteric blockade of ATP binding and hydrolysis via CDDO and its derivatives Lee, Jae

298 3 p.
artikel
52 Inhibition of the Na+/K+-ATPase by cardiac glycosides suppresses expression of the IDO1 immune checkpoint in cancer cells by reducing STAT1 activation Shandell, Mia A.

298 3 p.
artikel
53 Inositol triphosphate–triggered calcium release from the endoplasmic reticulum induces lysosome biogenesis via TFEB/TFE3 Malek, Mouhannad

298 3 p.
artikel
54 Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE2 Liu, Jiamnin

298 3 p.
artikel
55 Interaction of transcription factor FoxO3 with histone acetyltransferase complex subunit TRRAP modulates gene expression and apoptosis Fusi, Lorenza

298 3 p.
artikel
56 Intricate coupling between the transactivation and basic-leucine zipper domains governs phosphorylation of transcription factor ATF4 by casein kinase 2 Siang, Steven

298 3 p.
artikel
57 In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-γ1 in T cells Wada, Junya

298 3 p.
artikel
58 Loss of phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (Pip5k1c) in mesenchymal stem cells leads to osteopenia by impairing bone remodeling Yan, Qinnan

298 3 p.
artikel
59 Loss of the N-acetylgalactosamine side chain of the GPI-anchor impairs bone formation and brain functions and accelerates the prion disease pathology Hirata, Tetsuya

298 3 p.
artikel
60 LPGAT1 controls the stearate/palmitate ratio of phosphatidylethanolamine and phosphatidylcholine in sn-1 specific remodeling Xu, Yang

298 3 p.
artikel
61 Measurement of deaminated cytosine adducts in DNA using a novel hybrid thymine DNA glycosylase Hsu, Chia Wei

298 3 p.
artikel
62 Mechanistic insights into the inhibition of the CRISPR-Cas surveillance complex by anti-CRISPR protein AcrIF13 Wang, Hao

298 3 p.
artikel
63 Metabolic regulation of ferroptosis in the tumor microenvironment Mbah, Nneka E.

298 3 p.
artikel
64 Methyl-lysine readers PHF20 and PHF20L1 define two distinct gene expression–regulating NSL complexes Van, Hieu T.

298 3 p.
artikel
65 Mitochondrial respiratory chain dysfunction alters ER sterol sensing and mevalonate pathway activity Wall, Christopher Tadhg James

298 3 p.
artikel
66 Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol Niu, Canyang

298 3 p.
artikel
67 Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4 Gasparrini, Massimiliano

298 3 p.
artikel
68 Molecular insights into the maturation of phosphodiesterase 6 by the specialized chaperone complex of HSP90 with AIPL1 Yadav, Ravi P.

298 3 p.
artikel
69 Molecular mechanism of intramolecular electron transfer in dimeric sulfite oxidase Eh, Malin

298 3 p.
artikel
70 Multimodal regulation of myosin VI ensemble transport by cargo adaptor protein GIPC Rai, Ashim

298 3 p.
artikel
71 Myotubularin-related protein protects against neuronal degeneration mediated by oxidative stress or infection Kaur, Supender

298 3 p.
artikel
72 N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates Osuka, Reina F.

298 3 p.
artikel
73 New insights into the type A glycan modification of Clostridioides difficile flagellar protein flagellin C by phosphoproteomics analysis Hensbergen, Paul J.

298 3 p.
artikel
74 Nutrient-responsive O-GlcNAcylation dynamically modulates the secretion of glycan-binding protein galectin 3 Mathew, Mohit P.

298 3 p.
artikel
75 Occlusion of the human serotonin transporter is mediated by serotonin-induced conformational changes in the bundle domain Gradisch, Ralph

298 3 p.
artikel
76 Oligomerization of DNA replication regulatory protein RADX is essential to maintain replication fork stability Mohamed, Taha

298 3 p.
artikel
77 Oxidation of specific tryptophan residues inhibits high-affinity binding of cocaine and its metabolites to a humanized anticocaine mAb Kirley, Terence L.

298 3 p.
artikel
78 Oxidized alkyl phospholipids stimulate sodium transport in proximal tubules via a nongenomic PPARγ-dependent pathway Mizuno, Tomohito

298 3 p.
artikel
79 Peroxisome-generated succinate induces lipid accumulation and oxidative stress in the kidneys of diabetic mice Wang, Yaoqing

298 3 p.
artikel
80 Pharmacological chaperones for the oxytocin receptor increase oxytocin responsiveness in myometrial cells Malik, Manasi

298 3 p.
artikel
81 Phase separation by the SARS-CoV-2 nucleocapsid protein: Consensus and open questions Cascarina, Sean M.

298 3 p.
artikel
82 Prostate secretory protein 94 inhibits sterol binding and export by the mammalian CAP protein CRISP2 in a calcium-sensitive manner El Atab, Ola

298 3 p.
artikel
83 Proteomics, phylogenetics, and coexpression analyses indicate novel interactions in the plastid CLP chaperone-protease system Rei Liao, Jui-Yun

298 3 p.
artikel
84 Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE Tooker, Brian C.

298 3 p.
artikel
85 Recharacterization of the mammalian cytosolic type 2 (R)-β-hydroxybutyrate dehydrogenase as 4-oxo-l-proline reductase (EC 1.1.1.104) Kwiatkowski, Sebastian

298 3 p.
artikel
86 Recreating the natural evolutionary trend in key microdomains provides an effective strategy for engineering of a thermomicrobial N-demethylase Xin, Yu

298 3 p.
artikel
87 Redesigning therapies for pantothenate kinase–associated neurodegeneration Munshi, Muhammad I.

298 3 p.
artikel
88 Redox imbalance induces remodeling of glucose metabolism in Rhipicephalus microplus embryonic cell line Della Noce, Bárbara

298 3 p.
artikel
89 Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation Liao, Xiangwen

298 3 p.
artikel
90 Regulatory domains controlling high intestinal vitamin D receptor gene expression are conserved in mouse and human Fleet, James C.

298 3 p.
artikel
91 Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion Verma, Gaurav

298 3 p.
artikel
92 RNA-dependent synthesis of ergosteryl-3β-O-glycine in Ascomycota expands the diversity of steryl-amino acids Yakobov, Nathaniel

298 3 p.
artikel
93 SARS-CoV-2 accessory protein ORF8 is secreted extracellularly as a glycoprotein homodimer Matsuoka, Kazuhiro

298 3 p.
artikel
94 Separable structural requirements for cDNA synthesis, nontemplated extension, and template jumping by a non-LTR retroelement reverse transcriptase Pimentel, Sydney C.

298 3 p.
artikel
95 Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer Smithson, Mary

298 3 p.
artikel
96 SIRT6 stabilization and cytoplasmic localization in macrophages regulates acute and chronic inflammation in mice Bresque, Mariana

298 3 p.
artikel
97 SRC kinase activator CDCP1 promotes hepatocyte growth factor–induced cell migration/invasion of a subset of breast cancer cells Kawase, Naoyuki

298 3 p.
artikel
98 Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants Garcia, Adriana Ann

298 3 p.
artikel
99 Structural and functional analyses of the Porphyromonas gingivalis type IX secretion system PorN protein Fuchsbauer, Olivier

298 3 p.
artikel
100 Structural and functional analysis of the roles of influenza C virus membrane proteins in assembly and budding Zhang, Xu

298 3 p.
artikel
101 Structural and functional insights into the inhibition of human voltage-gated sodium channels by μ-conotoxin KIIIA disulfide isomers Tran, Hue N.T.

298 3 p.
artikel
102 Structural basis for dysregulation of aminolevulinic acid synthase in human disease Taylor, Jessica L.

298 3 p.
artikel
103 Structural basis for the recognition of methylated histone H3 by the Arabidopsis LHP1 chromodomain Liu, Yanli

298 3 p.
artikel
104 Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease Ciacchi, Laura

298 3 p.
artikel
105 Structural characterization of Linum usitatissimum hydroxynitrile lyase: A new cyanohydrin decomposition mechanism involving a cyano-zinc complex Zheng, Daijun

298 3 p.
artikel
106 Structural characterization of proton-pumping rhodopsin lacking a cytoplasmic proton donor residue by X-ray crystallography Suzuki, Kano

298 3 p.
artikel
107 Structural determinants of the dominant conformational epitopes of phospholipase A2 receptor in primary membranous nephropathy Tang, Hong

298 3 p.
artikel
108 Structural insights into how GlcNAc-1-phosphotransferase directs lysosomal protein transport Du, Shuo

298 3 p.
artikel
109 Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6 Ma, Lulu

298 3 p.
artikel
110 Subcellular regulation of glucose metabolism through multienzyme glucosome assemblies by EGF–ERK1/2 signaling pathways Jeon, Miji

298 3 p.
artikel
111 Substrate specificity and proposed structure of the proofreading complex of T7 DNA polymerase Dangerfield, Tyler L.

298 3 p.
artikel
112 Survival and infectivity of second-stage root-knot nematode Meloidogyne incognita juveniles depend on lysosome-mediated lipolysis Lu, Chao-Jun

298 3 p.
artikel
113 Tafenoquine and its derivatives as inhibitors for the severe acute respiratory syndrome coronavirus 2 Chen, Yeh

298 3 p.
artikel
114 Tailor made: New insights into lipoarabinomannan structure may improve TB diagnosis Lowary, Todd L.

298 3 p.
artikel
115 Targeting Wnt/tenascin C-mediated cross talk between pancreatic cancer cells and stellate cells via activation of the metastasis suppressor NDRG1 Geleta, Bekesho

298 3 p.
artikel
116 T-cell activation decreases miRNA-15a/16 levels to promote MEK1–ERK1/2–Elk1 signaling and proliferative capacity Urena, Frank

298 3 p.
artikel
117 T cell receptors employ diverse strategies to target a p53 cancer neoantigen Wu, Daichao

298 3 p.
artikel
118 TFPI2 suppresses the interaction of TGF-β2 pathway regulators to promote endothelial–mesenchymal transition in diabetic nephropathy Guan, Guoying

298 3 p.
artikel
119 The calcium-free form of atorvastatin inhibits amyloid-β(1–42) aggregation in vitro Nedaei, Hadi

298 3 p.
artikel
120 The cap-proximal RNA secondary structure inhibits preinitiation complex formation on HAC1 mRNA Uppala, Jagadeesh Kumar

298 3 p.
artikel
121 The carboxyl-terminal region of SDCCAG8 comprises a functional module essential for cilia formation as well as organ development and homeostasis Tsutsumi, Ryotaro

298 3 p.
artikel
122 The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity Schweininger, Johannes

298 3 p.
artikel
123 The hemerythrin-like diiron protein from Mycobacterium kansasii is a nitric oxide peroxidase Ma, Zhongxin

298 3 p.
artikel
124 The leucine-rich repeat domains of BK channel auxiliary γ subunits regulate their expression, trafficking, and channel-modulation functions Chen, Guanxing

298 3 p.
artikel
125 The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis Wong, Bernice H.

298 3 p.
artikel
126 The mammalian trafficking chaperone protein UNC93B1 maintains the ER calcium sensor STIM1 in a dimeric state primed for translocation to the ER cortex Wang, Wen-An

298 3 p.
artikel
127 The METTL5-TRMT112 N 6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation Sepich-Poore, Caraline

298 3 p.
artikel
128 The MuvB complex safeguards embryonic stem cell identity through regulation of the cell cycle machinery Wang, Congcong

298 3 p.
artikel
129 The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor Peng, Jinghua

298 3 p.
artikel
130 The Ragulator complex serves as a substrate-specific mTORC1 scaffold in regulating the nuclear translocation of transcription factor EB Kimura, Tetsuya

298 3 p.
artikel
131 The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression Protze, Johanna

298 3 p.
artikel
132 The spike protein of SARS-CoV-2 induces endothelial inflammation through integrin α5β1 and NF-κB signaling Robles, Juan Pablo

298 3 p.
artikel
133 The tetrameric structure of Plasmodium falciparum phosphoglycerate mutase is critical for optimal enzymatic activity Tehlan, Ankita

298 3 p.
artikel
134 The tocopherol transfer protein mediates vitamin E trafficking between cerebellar astrocytes and neurons Ulatowski, L.

298 3 p.
artikel
135 Transcription factor GATA4 drives RNA polymerase III-directed transcription and transformed cell proliferation through a filamin A/GATA4/SP1 pathway Zhang, Cheng

298 3 p.
artikel
136 Transforming growth factor-β challenge alters the N-, O-, and glycosphingolipid glycomes in PaTu-S pancreatic adenocarcinoma cells Zhang, Jing

298 3 p.
artikel
137 Trimethylguanosine synthase 1 is a novel regulator of pancreatic beta-cell mass and function Blandino-Rosano, Manuel

298 3 p.
artikel
138 TRIM34 modulates influenza virus-activated programmed cell death by targeting Z-DNA-binding protein 1 for K63-linked polyubiquitination Wang, Xiaoyan

298 3 p.
artikel
139 Two distinct classes of cochaperones compete for the EEVD motif in heat shock protein 70 to tune its chaperone activities Johnson, Oleta T.

298 3 p.
artikel
140 Xenophagy of invasive bacteria is differentially activated and modulated via a TLR-TRAF6-Beclin1 axis in echinoderms Shao, Yina

298 3 p.
artikel
141 Zafirlukast inhibits the growth of lung adenocarcinoma via inhibiting TMEM16A channel activity Shi, Sai

298 3 p.
artikel
                             141 gevonden resultaten
 
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