nr |
titel |
auteur |
tijdschrift |
jaar |
jaarg. |
afl. |
pagina('s) |
type |
1 |
A capped Tudor domain within a core subunit of the Sin3L/Rpd3L histone deacetylase complex binds to nucleic acid G-quadruplexes
|
Marcum, Ryan Dale |
|
|
298 |
2 |
p. |
artikel |
2 |
A cell culture platform for quantifying metabolic substrate oxidation in bicarbonate-buffered medium
|
Krycer, James R. |
|
|
298 |
2 |
p. |
artikel |
3 |
Adaptive chromatin remodeling and transcriptional changes of the functional kinome in tumor cells in response to targeted kinase inhibition
|
East, Michael P. |
|
|
298 |
2 |
p. |
artikel |
4 |
An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins
|
Brennan, Andrew |
|
|
298 |
2 |
p. |
artikel |
5 |
Analysis of normal levels of free glycosaminoglycans in urine and plasma in adults
|
Bratulic, Sinisa |
|
|
298 |
2 |
p. |
artikel |
6 |
A novel C-terminal DxRSDxE motif in ceramide synthases involved in dimer formation
|
Kim, Jiyoon L. |
|
|
298 |
2 |
p. |
artikel |
7 |
A novel leishmanial copper P-type ATPase plays a vital role in parasite infection and intracellular survival
|
Paul, Rupam |
|
|
298 |
2 |
p. |
artikel |
8 |
A small stem-loop-forming region within the 3′-UTR of a nonpolyadenylated LCMV mRNA promotes translation
|
Hashizume, Mei |
|
|
298 |
2 |
p. |
artikel |
9 |
Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4
|
Luo, Jiansong |
|
|
298 |
2 |
p. |
artikel |
10 |
Cover
|
|
|
|
298 |
2 |
p. |
artikel |
11 |
Cryo-EM structure of mouse TRPML2 in lipid nanodiscs
|
Song, Xiaojing |
|
|
298 |
2 |
p. |
artikel |
12 |
Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site
|
Goh, Boon Chong |
|
|
298 |
2 |
p. |
artikel |
13 |
Degradation of the E. coli antitoxin MqsA by the proteolytic complex ClpXP is regulated by zinc occupancy and oxidation
|
Vos, Margaret R. |
|
|
298 |
2 |
p. |
artikel |
14 |
Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer
|
Lee, Wing-Kee |
|
|
298 |
2 |
p. |
artikel |
15 |
Development of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence–based affinity maturation
|
Kielczewska, Agnieszka |
|
|
298 |
2 |
p. |
artikel |
16 |
Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic
|
Hagenston, Anna M. |
|
|
298 |
2 |
p. |
artikel |
17 |
During FeS cluster biogenesis, ferredoxin and frataxin use overlapping binding sites on yeast cysteine desulfurase Nfs1
|
Uzarska, Marta A. |
|
|
298 |
2 |
p. |
artikel |
18 |
Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir
|
Gordon, Calvin J. |
|
|
298 |
2 |
p. |
artikel |
19 |
Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria-causing parasites
|
Frasse, Philip M. |
|
|
298 |
2 |
p. |
artikel |
20 |
Exostosin glycosyltransferase 1 reduces porcine reproductive and respiratory syndrome virus infection through proteasomal degradation of nsp3 and nsp5
|
Zhang, Xiaoxiao |
|
|
298 |
2 |
p. |
artikel |
21 |
Gasdermin E mediates photoreceptor damage by all-trans-retinal in the mouse retina
|
Cai, Binxiang |
|
|
298 |
2 |
p. |
artikel |
22 |
Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells
|
Hanna, David A. |
|
|
298 |
2 |
p. |
artikel |
23 |
High-resolution structures of mitochondrial glutaminase C tetramers indicate conformational changes upon phosphate binding
|
Nguyen, Thuy-Tien T. |
|
|
298 |
2 |
p. |
artikel |
24 |
Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation
|
Zhou, Yuzheng |
|
|
298 |
2 |
p. |
artikel |
25 |
Hypoxia inhibits colonic uptake of the microbiota-generated forms of vitamin B1 via HIF-1α-mediated transcriptional regulation of their transporters
|
Sabui, Subrata |
|
|
298 |
2 |
p. |
artikel |
26 |
Identification and characterization of a noncanonical menaquinone-linked formate dehydrogenase
|
Arias-Cartín, Rodrigo |
|
|
298 |
2 |
p. |
artikel |
27 |
Induction, inhibition, and incorporation: Different roles for anionic and zwitterionic lysolipids in the fibrillation of the functional amyloid FapC
|
Rasmussen, Helena Østergaard |
|
|
298 |
2 |
p. |
artikel |
28 |
Inhibition of high-fat diet–induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms
|
Wang, Xiaolin |
|
|
298 |
2 |
p. |
artikel |
29 |
Inhibition of Jumonji demethylases reprograms severe dilated cardiomyopathy and prolongs survival
|
Tran, Tram Anh |
|
|
298 |
2 |
p. |
artikel |
30 |
Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA
|
Martinez, Orlando E. |
|
|
298 |
2 |
p. |
artikel |
31 |
Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins
|
Sun, Lingbo |
|
|
298 |
2 |
p. |
artikel |
32 |
Interaction of DBC1 with polyoma small T antigen promotes its degradation and negatively regulates tumorigenesis
|
Sarwar, Zarka |
|
|
298 |
2 |
p. |
artikel |
33 |
Interleukin-22 regulates B3GNT7 expression to induce fucosylation of glycoproteins in intestinal epithelial cells
|
Carroll, Daniela J. |
|
|
298 |
2 |
p. |
artikel |
34 |
Intra-islet glucagon confers β-cell glucose competence for first-phase insulin secretion and favors GLP-1R stimulation by exogenous glucagon
|
Cabrera, Over |
|
|
298 |
2 |
p. |
artikel |
35 |
Investigation of sugar binding kinetics of the E. coli sugar/H+ symporter XylE using solid-supported membrane-based electrophysiology
|
Bazzone, Andre |
|
|
298 |
2 |
p. |
artikel |
36 |
m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis
|
Gao, Ming |
|
|
298 |
2 |
p. |
artikel |
37 |
MCU (mitochondrial Ca2+ uniporter) makes the calcium go round
|
Walters, Grant C. |
|
|
298 |
2 |
p. |
artikel |
38 |
Mechanism of Atg9 recruitment by Atg11 in the cytoplasm-to-vacuole targeting pathway
|
Coudevylle, Nicolas |
|
|
298 |
2 |
p. |
artikel |
39 |
Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface
|
Karuppan, Sebastian J. |
|
|
298 |
2 |
p. |
artikel |
40 |
Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice
|
Hodges, Wesley T. |
|
|
298 |
2 |
p. |
artikel |
41 |
Molecular and in vivo phenotyping of missense variants of the human glucagon receptor
|
van der Velden, Wijnand J.C. |
|
|
298 |
2 |
p. |
artikel |
42 |
Monomethyl branched-chain fatty acids are critical for Caenorhabitis elegans survival in elevated glucose conditions
|
Vieira, Andre F.C. |
|
|
298 |
2 |
p. |
artikel |
43 |
Mutant phosphatidate phosphatase Pah1-W637A exhibits altered phosphorylation, membrane association, and enzyme function in yeast
|
Park, Yeonhee |
|
|
298 |
2 |
p. |
artikel |
44 |
New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography
|
Milano, Shawn K. |
|
|
298 |
2 |
p. |
artikel |
45 |
Nonselective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903
|
Baradaran-Heravi, Alireza |
|
|
298 |
2 |
p. |
artikel |
46 |
Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose
|
Overway, Emily M. |
|
|
298 |
2 |
p. |
artikel |
47 |
Not a “they” but a “we”: The microbiome helps promote our well-being
|
Ragsdale, Stephen W. |
|
|
298 |
2 |
p. |
artikel |
48 |
Peroxisomal β-oxidation stimulates cholesterol biosynthesis in the liver in diabetic mice
|
Zhang, Xiao |
|
|
298 |
2 |
p. |
artikel |
49 |
Phosphorylation of the aggregate-forming protein alpha-synuclein on serine-129 inhibits its DNA-bending properties
|
Dent, Sydney E. |
|
|
298 |
2 |
p. |
artikel |
50 |
Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding
|
Timmermans, Steven |
|
|
298 |
2 |
p. |
artikel |
51 |
p53 regulates skeletal muscle mitophagy and mitochondrial quality control following denervation-induced muscle disuse
|
Memme, Jonathan M. |
|
|
298 |
2 |
p. |
artikel |
52 |
Protein acetylation-mediated cross regulation of acetic acid and ethanol synthesis in the gas-fermenting Clostridium ljungdahlii
|
Liu, Yanqiang |
|
|
298 |
2 |
p. |
artikel |
53 |
RNA-binding protein RBM28 can translocate from the nucleolus to the nucleoplasm to inhibit the transcriptional activity of p53
|
Lin, Xin |
|
|
298 |
2 |
p. |
artikel |
54 |
Selective activation of TRPA1 ion channels by nitrobenzene skin sensitizers DNFB and DNCB
|
Wu, Han |
|
|
298 |
2 |
p. |
artikel |
55 |
Signaling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages
|
Williams, Niamh C. |
|
|
298 |
2 |
p. |
artikel |
56 |
Skeletal muscle myosin promotes coagulation by binding factor XI via its A3 domain and enhancing thrombin-induced factor XI activation
|
Morla, Shravan |
|
|
298 |
2 |
p. |
artikel |
57 |
Stepwise assembly of the eukaryotic translation initiation factor 2 complex
|
Vanselow, Sven |
|
|
298 |
2 |
p. |
artikel |
58 |
Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems
|
Xia, Pengjun |
|
|
298 |
2 |
p. |
artikel |
59 |
Structural determinants of the interactions of catechins with Aβ oligomers and lipid membranes
|
Ahmed, Rashik |
|
|
298 |
2 |
p. |
artikel |
60 |
Structural insights into the specific interaction between Geobacillus stearothermophilus tryptophanyl-tRNA synthetase and antimicrobial Chuangxinmycin
|
Fan, Shuai |
|
|
298 |
2 |
p. |
artikel |
61 |
Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family: Tidying up diversity
|
Borza, Razvan |
|
|
298 |
2 |
p. |
artikel |
62 |
The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase
|
Heppler, Lisa N. |
|
|
298 |
2 |
p. |
artikel |
63 |
The ASCC2 CUE domain in the ALKBH3–ASCC DNA repair complex recognizes adjacent ubiquitins in K63-linked polyubiquitin
|
Lombardi, Patrick M. |
|
|
298 |
2 |
p. |
artikel |
64 |
The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms
|
Paiardi, Giulia |
|
|
298 |
2 |
p. |
artikel |
65 |
The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation
|
Moretti, Leandro |
|
|
298 |
2 |
p. |
artikel |
66 |
The protease SENP2 controls hepatic gluconeogenesis by regulating the SUMOylation of the fuel sensor AMPKα
|
Dou, Xin |
|
|
298 |
2 |
p. |
artikel |
67 |
The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesis
|
Gheorghita, Andreea A. |
|
|
298 |
2 |
p. |
artikel |
68 |
The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation
|
Kulicke, Corinna A. |
|
|
298 |
2 |
p. |
artikel |
69 |
The Rho guanine nucleotide exchange factor PLEKHG1 is activated by interaction with and phosphorylation by Src family kinase member FYN
|
Nakano, Shun |
|
|
298 |
2 |
p. |
artikel |
70 |
The ubiquitin-binding domain of DNA polymerase η directly binds to DNA clamp PCNA and regulates translesion DNA synthesis
|
Manohar, Kodavati |
|
|
298 |
2 |
p. |
artikel |
71 |
The vital hormone 20-hydroxyecdysone controls ATP production by upregulating binding of trehalase 1 with ATP synthase subunit α in Helicoverpa armigera
|
Chang, Yanpeng |
|
|
298 |
2 |
p. |
artikel |
72 |
The yapsin family of aspartyl proteases regulate glucose homeostasis in Candida glabrata
|
Askari, Fizza |
|
|
298 |
2 |
p. |
artikel |
73 |
Tribbles 2 pseudokinase confers enzalutamide resistance in prostate cancer by promoting lineage plasticity
|
Monga, Jitender |
|
|
298 |
2 |
p. |
artikel |
74 |
Tumor necrosis factor α upregulates the bile acid efflux transporter OATP3A1 via multiple signaling pathways in cholestasis
|
Li, Mingqiao |
|
|
298 |
2 |
p. |
artikel |
75 |
Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd
|
Lee, Hyeyoon |
|
|
298 |
2 |
p. |
artikel |
76 |
Unique B-1 cells specific for both N-pyrrolated proteins and DNA evolve with apolipoprotein E deficiency
|
Lim, Sei-Young |
|
|
298 |
2 |
p. |
artikel |
77 |
Unraveling three-dimensional chromatin structural dynamics during spermatogonial differentiation
|
Zheng, Yi |
|
|
298 |
2 |
p. |
artikel |
78 |
Watching liquid droplets of TDP-43CTD age by Raman spectroscopy
|
Shuster, Sydney O. |
|
|
298 |
2 |
p. |
artikel |