Digitale Bibliotheek
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                             78 gevonden resultaten
nr titel auteur tijdschrift jaar jaarg. afl. pagina('s) type
1 A capped Tudor domain within a core subunit of the Sin3L/Rpd3L histone deacetylase complex binds to nucleic acid G-quadruplexes Marcum, Ryan Dale

298 2 p.
artikel
2 A cell culture platform for quantifying metabolic substrate oxidation in bicarbonate-buffered medium Krycer, James R.

298 2 p.
artikel
3 Adaptive chromatin remodeling and transcriptional changes of the functional kinome in tumor cells in response to targeted kinase inhibition East, Michael P.

298 2 p.
artikel
4 An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins Brennan, Andrew

298 2 p.
artikel
5 Analysis of normal levels of free glycosaminoglycans in urine and plasma in adults Bratulic, Sinisa

298 2 p.
artikel
6 A novel C-terminal DxRSDxE motif in ceramide synthases involved in dimer formation Kim, Jiyoon L.

298 2 p.
artikel
7 A novel leishmanial copper P-type ATPase plays a vital role in parasite infection and intracellular survival Paul, Rupam

298 2 p.
artikel
8 A small stem-loop-forming region within the 3′-UTR of a nonpolyadenylated LCMV mRNA promotes translation Hashizume, Mei

298 2 p.
artikel
9 Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4 Luo, Jiansong

298 2 p.
artikel
10 Cover
298 2 p.
artikel
11 Cryo-EM structure of mouse TRPML2 in lipid nanodiscs Song, Xiaojing

298 2 p.
artikel
12 Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site Goh, Boon Chong

298 2 p.
artikel
13 Degradation of the E. coli antitoxin MqsA by the proteolytic complex ClpXP is regulated by zinc occupancy and oxidation Vos, Margaret R.

298 2 p.
artikel
14 Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer Lee, Wing-Kee

298 2 p.
artikel
15 Development of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence–based affinity maturation Kielczewska, Agnieszka

298 2 p.
artikel
16 Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic Hagenston, Anna M.

298 2 p.
artikel
17 During FeS cluster biogenesis, ferredoxin and frataxin use overlapping binding sites on yeast cysteine desulfurase Nfs1 Uzarska, Marta A.

298 2 p.
artikel
18 Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir Gordon, Calvin J.

298 2 p.
artikel
19 Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria-causing parasites Frasse, Philip M.

298 2 p.
artikel
20 Exostosin glycosyltransferase 1 reduces porcine reproductive and respiratory syndrome virus infection through proteasomal degradation of nsp3 and nsp5 Zhang, Xiaoxiao

298 2 p.
artikel
21 Gasdermin E mediates photoreceptor damage by all-trans-retinal in the mouse retina Cai, Binxiang

298 2 p.
artikel
22 Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells Hanna, David A.

298 2 p.
artikel
23 High-resolution structures of mitochondrial glutaminase C tetramers indicate conformational changes upon phosphate binding Nguyen, Thuy-Tien T.

298 2 p.
artikel
24 Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation Zhou, Yuzheng

298 2 p.
artikel
25 Hypoxia inhibits colonic uptake of the microbiota-generated forms of vitamin B1 via HIF-1α-mediated transcriptional regulation of their transporters Sabui, Subrata

298 2 p.
artikel
26 Identification and characterization of a noncanonical menaquinone-linked formate dehydrogenase Arias-Cartín, Rodrigo

298 2 p.
artikel
27 Induction, inhibition, and incorporation: Different roles for anionic and zwitterionic lysolipids in the fibrillation of the functional amyloid FapC Rasmussen, Helena Østergaard

298 2 p.
artikel
28 Inhibition of high-fat diet–induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms Wang, Xiaolin

298 2 p.
artikel
29 Inhibition of Jumonji demethylases reprograms severe dilated cardiomyopathy and prolongs survival Tran, Tram Anh

298 2 p.
artikel
30 Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA Martinez, Orlando E.

298 2 p.
artikel
31 Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins Sun, Lingbo

298 2 p.
artikel
32 Interaction of DBC1 with polyoma small T antigen promotes its degradation and negatively regulates tumorigenesis Sarwar, Zarka

298 2 p.
artikel
33 Interleukin-22 regulates B3GNT7 expression to induce fucosylation of glycoproteins in intestinal epithelial cells Carroll, Daniela J.

298 2 p.
artikel
34 Intra-islet glucagon confers β-cell glucose competence for first-phase insulin secretion and favors GLP-1R stimulation by exogenous glucagon Cabrera, Over

298 2 p.
artikel
35 Investigation of sugar binding kinetics of the E. coli sugar/H+ symporter XylE using solid-supported membrane-based electrophysiology Bazzone, Andre

298 2 p.
artikel
36 m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis Gao, Ming

298 2 p.
artikel
37 MCU (mitochondrial Ca2+ uniporter) makes the calcium go round Walters, Grant C.

298 2 p.
artikel
38 Mechanism of Atg9 recruitment by Atg11 in the cytoplasm-to-vacuole targeting pathway Coudevylle, Nicolas

298 2 p.
artikel
39 Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface Karuppan, Sebastian J.

298 2 p.
artikel
40 Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice Hodges, Wesley T.

298 2 p.
artikel
41 Molecular and in vivo phenotyping of missense variants of the human glucagon receptor van der Velden, Wijnand J.C.

298 2 p.
artikel
42 Monomethyl branched-chain fatty acids are critical for Caenorhabitis elegans survival in elevated glucose conditions Vieira, Andre F.C.

298 2 p.
artikel
43 Mutant phosphatidate phosphatase Pah1-W637A exhibits altered phosphorylation, membrane association, and enzyme function in yeast Park, Yeonhee

298 2 p.
artikel
44 New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography Milano, Shawn K.

298 2 p.
artikel
45 Nonselective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903 Baradaran-Heravi, Alireza

298 2 p.
artikel
46 Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose Overway, Emily M.

298 2 p.
artikel
47 Not a “they” but a “we”: The microbiome helps promote our well-being Ragsdale, Stephen W.

298 2 p.
artikel
48 Peroxisomal β-oxidation stimulates cholesterol biosynthesis in the liver in diabetic mice Zhang, Xiao

298 2 p.
artikel
49 Phosphorylation of the aggregate-forming protein alpha-synuclein on serine-129 inhibits its DNA-bending properties Dent, Sydney E.

298 2 p.
artikel
50 Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding Timmermans, Steven

298 2 p.
artikel
51 p53 regulates skeletal muscle mitophagy and mitochondrial quality control following denervation-induced muscle disuse Memme, Jonathan M.

298 2 p.
artikel
52 Protein acetylation-mediated cross regulation of acetic acid and ethanol synthesis in the gas-fermenting Clostridium ljungdahlii Liu, Yanqiang

298 2 p.
artikel
53 RNA-binding protein RBM28 can translocate from the nucleolus to the nucleoplasm to inhibit the transcriptional activity of p53 Lin, Xin

298 2 p.
artikel
54 Selective activation of TRPA1 ion channels by nitrobenzene skin sensitizers DNFB and DNCB Wu, Han

298 2 p.
artikel
55 Signaling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages Williams, Niamh C.

298 2 p.
artikel
56 Skeletal muscle myosin promotes coagulation by binding factor XI via its A3 domain and enhancing thrombin-induced factor XI activation Morla, Shravan

298 2 p.
artikel
57 Stepwise assembly of the eukaryotic translation initiation factor 2 complex Vanselow, Sven

298 2 p.
artikel
58 Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems Xia, Pengjun

298 2 p.
artikel
59 Structural determinants of the interactions of catechins with Aβ oligomers and lipid membranes Ahmed, Rashik

298 2 p.
artikel
60 Structural insights into the specific interaction between Geobacillus stearothermophilus tryptophanyl-tRNA synthetase and antimicrobial Chuangxinmycin Fan, Shuai

298 2 p.
artikel
61 Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family: Tidying up diversity Borza, Razvan

298 2 p.
artikel
62 The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase Heppler, Lisa N.

298 2 p.
artikel
63 The ASCC2 CUE domain in the ALKBH3–ASCC DNA repair complex recognizes adjacent ubiquitins in K63-linked polyubiquitin Lombardi, Patrick M.

298 2 p.
artikel
64 The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms Paiardi, Giulia

298 2 p.
artikel
65 The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation Moretti, Leandro

298 2 p.
artikel
66 The protease SENP2 controls hepatic gluconeogenesis by regulating the SUMOylation of the fuel sensor AMPKα Dou, Xin

298 2 p.
artikel
67 The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesis Gheorghita, Andreea A.

298 2 p.
artikel
68 The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation Kulicke, Corinna A.

298 2 p.
artikel
69 The Rho guanine nucleotide exchange factor PLEKHG1 is activated by interaction with and phosphorylation by Src family kinase member FYN Nakano, Shun

298 2 p.
artikel
70 The ubiquitin-binding domain of DNA polymerase η directly binds to DNA clamp PCNA and regulates translesion DNA synthesis Manohar, Kodavati

298 2 p.
artikel
71 The vital hormone 20-hydroxyecdysone controls ATP production by upregulating binding of trehalase 1 with ATP synthase subunit α in Helicoverpa armigera Chang, Yanpeng

298 2 p.
artikel
72 The yapsin family of aspartyl proteases regulate glucose homeostasis in Candida glabrata Askari, Fizza

298 2 p.
artikel
73 Tribbles 2 pseudokinase confers enzalutamide resistance in prostate cancer by promoting lineage plasticity Monga, Jitender

298 2 p.
artikel
74 Tumor necrosis factor α upregulates the bile acid efflux transporter OATP3A1 via multiple signaling pathways in cholestasis Li, Mingqiao

298 2 p.
artikel
75 Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd Lee, Hyeyoon

298 2 p.
artikel
76 Unique B-1 cells specific for both N-pyrrolated proteins and DNA evolve with apolipoprotein E deficiency Lim, Sei-Young

298 2 p.
artikel
77 Unraveling three-dimensional chromatin structural dynamics during spermatogonial differentiation Zheng, Yi

298 2 p.
artikel
78 Watching liquid droplets of TDP-43CTD age by Raman spectroscopy Shuster, Sydney O.

298 2 p.
artikel
                             78 gevonden resultaten
 
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